This is a Validated Antibody Database (VAD) review about rat Abca1, based on 41 published articles (read how Labome selects the articles), using Abca1 antibody in all methods. It is aimed to help Labome visitors find the most suited Abca1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Abcam
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 4a, s3
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 4a, s3). Cell Death Dis (2022) ncbi
mouse monoclonal (HJ1)
  • western blot; mouse; 1:1000; loading ...; fig s4a
Abcam Abca1 antibody (Abcam, ab66217) was used in western blot on mouse samples at 1:1000 (fig s4a). Mol Ther Nucleic Acids (2021) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; 1:1000; loading ...; fig 1c
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples at 1:1000 (fig 1c). Proc Natl Acad Sci U S A (2021) ncbi
mouse monoclonal (AB.H10)
  • immunocytochemistry; human; loading ...; fig 5a
Abcam Abca1 antibody (Abcam, ab18180) was used in immunocytochemistry on human samples (fig 5a). Biomolecules (2021) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 2
Abcam Abca1 antibody (abcam, Ab18180) was used in western blot on mouse samples (fig 2). Int J Mol Sci (2020) ncbi
mouse monoclonal (AB.H10)
  • western blot; human; loading ...; fig 8e
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on human samples (fig 8e). Toxicology (2019) ncbi
mouse monoclonal (AB.H10)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s3c
  • western blot; mouse; 1:200; loading ...; fig s3b
Abcam Abca1 antibody (Abcam, ab18180) was used in immunocytochemistry on mouse samples at 1:100 (fig s3c) and in western blot on mouse samples at 1:200 (fig s3b). Nat Commun (2019) ncbi
mouse monoclonal (AB.H10)
  • immunohistochemistry - frozen section; mouse; loading ...; fig 14c
  • western blot; mouse; loading ...; fig 13a
Abcam Abca1 antibody (Abcam, ab18180) was used in immunohistochemistry - frozen section on mouse samples (fig 14c) and in western blot on mouse samples (fig 13a). J Am Heart Assoc (2018) ncbi
mouse monoclonal (AB.H10)
  • western blot; human; loading ...; fig 2b
In order to determine that the transcriptional activities of liver X receptor alpha and beta are activated by raffinose, Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on human samples (fig 2b). Sci Rep (2017) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 1a
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 1a). Sci Rep (2017) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; 1:500; loading ...; fig 5a
In order to analyze the effect of a high-fat diet on liver morphology and physiology, lipid metabolism, immune signaling, energy homeostasis, and stress responses during acute Trypanosoma cruzi infection, Abcam Abca1 antibody (Abcam, AB.H10) was used in western blot on mouse samples at 1:500 (fig 5a). Parasitol Res (2017) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; 1:2000; loading ...; fig 6d
In order to describe how amino acids and Lamtor1 regulate macrophage polarization, Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples at 1:2000 (fig 6d). Nat Commun (2016) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 5d
In order to investigate how leoligin modulates cholesterol levels, Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 5d). J Mol Cell Cardiol (2016) ncbi
mouse monoclonal (AB.H10)
  • immunocytochemistry; mouse; 1:1000; fig 7h
  • western blot; mouse; 1:1000; fig 7f
In order to elucidate how hematopoietic ANGPTL4 deficiency increases atherogenesis, Abcam Abca1 antibody (Abcam, ab18180) was used in immunocytochemistry on mouse samples at 1:1000 (fig 7h) and in western blot on mouse samples at 1:1000 (fig 7f). Nat Commun (2016) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; 1:1000; fig 3
Abcam Abca1 antibody (abcam, ab18180) was used in western blot on mouse samples at 1:1000 (fig 3). J Neuroinflammation (2016) ncbi
mouse monoclonal (HJ1)
  • western blot; mouse; 1:1000; loading ...; fig 4a
In order to test if a LXR agonist affects cognitive impairment in amyloid and Tau Alzheimer's disease mouse models, Abcam Abca1 antibody (Abcam, AB66217) was used in western blot on mouse samples at 1:1000 (fig 4a). PLoS ONE (2015) ncbi
mouse monoclonal (AB.H10)
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 5
Abcam Abca1 antibody (Abcam, ab18180) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 5). Cell Death Differ (2016) ncbi
mouse monoclonal (AB.H10)
  • western blot; human; loading ...; fig 6e
  • western blot; mouse; loading ...; fig 6a
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on human samples (fig 6e) and in western blot on mouse samples (fig 6a). Nat Med (2015) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 3c
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 3c). Nat Commun (2015) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; loading ...; fig 7B
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 7B). Sci Rep (2015) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; fig 3
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples (fig 3). EMBO J (2015) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples . J Mol Cell Cardiol (2015) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse; 1:1000; fig 6
In order to determine the effect of high fat diet on regulating acute T. cruzi infection-induced myocarditis, Abcam Abca1 antibody (Abcam, AB18180) was used in western blot on mouse samples at 1:1000 (fig 6). PLoS Negl Trop Dis (2014) ncbi
mouse monoclonal (AB.H10)
  • immunohistochemistry - paraffin section; human
Abcam Abca1 antibody (Abcam, ab18180) was used in immunohistochemistry - paraffin section on human samples . J Lipid Res (2014) ncbi
mouse monoclonal (AB.H10)
  • western blot; mouse
Abcam Abca1 antibody (Abcam, ab18180) was used in western blot on mouse samples . J Biol Chem (2014) ncbi
Novus Biologicals
mouse monoclonal (HJ1)
  • western blot; rat; 1:2000; loading ...; fig 4e, 8b
Novus Biologicals Abca1 antibody (Novus Biologicals, NB100-2068) was used in western blot on rat samples at 1:2000 (fig 4e, 8b). Life Sci Alliance (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunohistochemistry; mouse; loading ...; fig 4d
  • western blot; mouse; loading ...; fig 4c
Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105SS) was used in immunohistochemistry on mouse samples (fig 4d) and in western blot on mouse samples (fig 4c). Sci Rep (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 1f
Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105) was used in western blot on mouse samples (fig 1f). Nat Commun (2021) ncbi
domestic rabbit polyclonal (OTI2B3)
  • immunocytochemistry; mouse; loading ...; fig 7d
  • western blot; mouse; loading ...; fig 7b
Novus Biologicals Abca1 antibody (Novus, NB400-105) was used in immunocytochemistry on mouse samples (fig 7d) and in western blot on mouse samples (fig 7b). Front Cell Dev Biol (2020) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 5b
Novus Biologicals Abca1 antibody (Novus, NB400-105) was used in western blot on mouse samples (fig 5b). J Neuroinflammation (2018) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; loading ...; fig 5d
  • western blot; mouse; loading ...; fig 6d
In order to identify genes involved in liver X receptor-stimulated cholesterol efflux, Novus Biologicals Abca1 antibody (Novus, NB400-105) was used in western blot on human samples (fig 5d) and in western blot on mouse samples (fig 6d). Arterioscler Thromb Vasc Biol (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; human; 1:500; fig 3a
Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105) was used in western blot on human samples at 1:500 (fig 3a). Mol Nutr Food Res (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; bovine; 1:1000; loading ...; tbl 2
In order to study the transport of cholesterol and phospholipids in mammary epithelial cells, Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105) was used in western blot on bovine samples at 1:1000 (tbl 2). Mol Cell Endocrinol (2017) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig s5a
In order to study the effects of apolipoprotein B inhibition on VLDL levels and hepatic lipids in mice., Novus Biologicals Abca1 antibody (Novus, 400-105) was used in western blot on mouse samples (fig s5a). J Clin Invest (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; rat; fig 4
Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105) was used in western blot on rat samples (fig 4). Physiol Rep (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; loading ...; fig 1a
In order to describe the ubiquitination and degradation of liver X receptor, Novus Biologicals Abca1 antibody (Novus Biologicals, NB400-105) was used in western blot on mouse samples (fig 1a). Nature (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
  • western blot; mouse; 1:1000; fig 3
  • western blot; human; 1:1000; fig 3
In order to investigate the impact of PUFAs membrane incorporation on ABCA1-mediated cholesterol efflux, Novus Biologicals Abca1 antibody (Novus Biologicals, NB 400-105) was used in western blot on mouse samples at 1:1000 (fig 3) and in western blot on human samples at 1:1000 (fig 3). Biochim Biophys Acta (2016) ncbi
domestic rabbit polyclonal (OTI2B3)
Novus Biologicals Abca1 antibody (Novus Biologicals, 400-105) was used . PLoS ONE (2015) ncbi
domestic rabbit polyclonal (OTI2B3)
In order to report that liver X receptors modulate inflammation by altering lipid metabolism, Novus Biologicals Abca1 antibody (Novus, NB400-105) was used . elife (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • flow cytometry; mouse; loading ...; fig 5a
In order to show that the MEK1/2 pathway is a key regulator of macrophage reparative properties, Invitrogen Abca1 antibody (Pierce, PA5-22908) was used in flow cytometry on mouse samples (fig 5a). J Immunol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 2
In order to elucidate the role of calpains from T lymphocytes and IL-17 expression, Invitrogen Abca1 antibody (Thermo Fisher, PA1-16789) was used in western blot on mouse samples at 1:500 (fig 2). J Immunol (2016) ncbi
Articles Reviewed
  1. Jin Y, Liu Y, Xu L, Xu J, Xiong Y, Peng Y, et al. Novel role for caspase 1 inhibitor VX765 in suppressing NLRP3 inflammasome assembly and atherosclerosis via promoting mitophagy and efferocytosis. Cell Death Dis. 2022;13:512 pubmed publisher
  2. Guix F, Capitán A, Casadomé Perales Á, Palomares Perez I, López Del Castillo I, Miguel V, et al. Increased exosome secretion in neurons aging in vitro by NPC1-mediated endosomal cholesterol buildup. Life Sci Alliance. 2021;4: pubmed publisher
  3. Zhang Z, Wen H, Peng B, Weng J, Zeng F. HFD-induced TRAF6 upregulation promotes liver cholesterol accumulation and fatty liver development via EZH2-mediated miR-429/PPARα axis. Mol Ther Nucleic Acids. 2021;24:711-727 pubmed publisher
  4. Brampton C, Pomozi V, Chen L, Apana A, McCurdy S, Zoll J, et al. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Sci Rep. 2021;11:3881 pubmed publisher
  5. Horie T, Nakao T, Miyasaka Y, Nishino T, Matsumura S, Nakazeki F, et al. microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity. Nat Commun. 2021;12:843 pubmed publisher
  6. Price N, Zhang X, Fernández Tussy P, Singh A, Burnap S, Rotllan N, et al. Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  7. Lv J, Wang H, Cui H, Liu Z, Zhang R, Lu M, et al. Blockade of Macrophage CD147 Protects Against Foam Cell Formation in Atherosclerosis. Front Cell Dev Biol. 2020;8:609090 pubmed publisher
  8. Wanschel A, Guizoni D, Lorza Gil E, Salerno A, Paiva A, Dorighello G, et al. The Presence of Cholesteryl Ester Transfer Protein (CETP) in Endothelial Cells Generates Vascular Oxidative Stress and Endothelial Dysfunction. Biomolecules. 2021;11: pubmed publisher
  9. Kim Y, Oh S, Ahn J, Yook J, Kim C, Park S, et al. The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia. Int J Mol Sci. 2020;21: pubmed publisher
  10. Zhang G, Zhou J, Huang W, Fang M, Yu L, Wang H, et al. Prenatal ethanol exposure-induced a low level of foetal blood cholesterol and its mechanism of IGF1-related placental cholesterol transport dysfunction. Toxicology. 2019;:152237 pubmed publisher
  11. Fan J, Liu L, Liu Q, Cui Y, Yao B, Zhang M, et al. CKIP-1 limits foam cell formation and inhibits atherosclerosis by promoting degradation of Oct-1 by REGγ. Nat Commun. 2019;10:425 pubmed publisher
  12. Casali B, Reed Geaghan E, Landreth G. Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer's disease. J Neuroinflammation. 2018;15:43 pubmed publisher
  13. Wen G, An W, Chen J, Maguire E, Chen Q, Yang F, et al. Genetic and Pharmacologic Inhibition of the Neutrophil Elastase Inhibits Experimental Atherosclerosis. J Am Heart Assoc. 2018;7: pubmed publisher
  14. Na T, Kim G, Oh H, Lee M, Han Y, Kim K, et al. The trisaccharide raffinose modulates epidermal differentiation through activation of liver X receptor. Sci Rep. 2017;7:43823 pubmed publisher
  15. Vienken H, Mabrouki N, Grabau K, Claas R, Rudowski A, Schömel N, et al. Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage. Sci Rep. 2017;7:43575 pubmed publisher
  16. Nelson J, Koenis D, Scheij S, Cook E, Moeton M, Santos A, et al. EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. Arterioscler Thromb Vasc Biol. 2017;37:423-432 pubmed publisher
  17. Long M, Eddy W, Gong K, Lovelace Macon L, McMahan R, Charron J, et al. MEK1/2 Inhibition Promotes Macrophage Reparative Properties. J Immunol. 2017;198:862-872 pubmed publisher
  18. Lizardo K, Almonte V, Law C, Aiyyappan J, Cui M, Nagajyothi J. Diet regulates liver autophagy differentially in murine acute Trypanosoma cruzi infection. Parasitol Res. 2017;116:711-723 pubmed publisher
  19. Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, et al. Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages. Mol Nutr Food Res. 2017;61: pubmed publisher
  20. Ontsouka C, Huang X, Aliyev E, Albrecht C. In vitro characterization and endocrine regulation of cholesterol and phospholipid transport in the mammary gland. Mol Cell Endocrinol. 2017;439:35-45 pubmed publisher
  21. Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
  22. Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher
  23. Scharinger B, Messner B, Türkcan A, Schuster D, Vuorinen A, Pitterl F, et al. Leoligin, the major lignan from Edelweiss, inhibits 3-hydroxy-3-methyl-glutaryl-CoA reductase and reduces cholesterol levels in ApoE-/- mice. J Mol Cell Cardiol. 2016;99:35-46 pubmed publisher
  24. Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
  25. Zinkhan E, Zalla J, Carpenter J, Yu B, Yu X, Chan G, et al. Intrauterine growth restriction combined with a maternal high-fat diet increases hepatic cholesterol and low-density lipoprotein receptor activity in rats. Physiol Rep. 2016;4: pubmed publisher
  26. Hsieh J, Koseki M, Molusky M, Yakushiji E, Ichi I, Westerterp M, et al. TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis. Nature. 2016;535:303-7 pubmed publisher
  27. Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed publisher
  28. Fournier N, Tardivel S, Benoist J, Vedie B, Rousseau Ralliard D, Nowak M, et al. Eicosapentaenoic acid membrane incorporation impairs ABCA1-dependent cholesterol efflux via a protein kinase A signaling pathway in primary human macrophages. Biochim Biophys Acta. 2016;1861:331-41 pubmed publisher
  29. Sandoval Hernández A, Buitrago L, Moreno H, Cardona Gómez G, Arboleda G. Role of Liver X Receptor in AD Pathophysiology. PLoS ONE. 2015;10:e0145467 pubmed publisher
  30. Perez J, Dansou B, Hervé R, Levi C, Tamouza H, Vandermeersch S, et al. Calpains Released by T Lymphocytes Cleave TLR2 To Control IL-17 Expression. J Immunol. 2016;196:168-81 pubmed publisher
  31. Dong Y, Hou W, Li Y, Liu D, Hao G, Zhang H, et al. Unexpected requirement for a binding partner of the syntaxin family in phagocytosis by murine testicular Sertoli cells. Cell Death Differ. 2016;23:787-800 pubmed publisher
  32. Goedeke L, Rotllan N, Canfrán Duque A, Aranda J, Ramírez C, Araldi E, et al. MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. Nat Med. 2015;21:1280-9 pubmed publisher
  33. Hussein M, Shrestha E, Ouimet M, Barrett T, Leone S, Moore K, et al. LXR-Mediated ABCA1 Expression and Function Are Modulated by High Glucose and PRMT2. PLoS ONE. 2015;10:e0135218 pubmed publisher
  34. Ito A, Hong C, Rong X, Zhu X, Tarling E, Hedde P, et al. LXRs link metabolism to inflammation through Abca1-dependent regulation of membrane composition and TLR signaling. elife. 2015;4:e08009 pubmed publisher
  35. Singh N, Kotla S, Dyukova E, Traylor J, Orr A, Chernoff J, et al. Disruption of p21-activated kinase 1 gene diminishes atherosclerosis in apolipoprotein E-deficient mice. Nat Commun. 2015;6:7450 pubmed publisher
  36. Zhong C, Sun W, Ma Y, Zhu H, Yang P, Wei H, et al. Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice. Sci Rep. 2015;5:10512 pubmed publisher
  37. Gillespie M, Gold E, Ramsey S, Podolsky I, Aderem A, Ranish J. An LXR-NCOA5 gene regulatory complex directs inflammatory crosstalk-dependent repression of macrophage cholesterol efflux. EMBO J. 2015;34:1244-58 pubmed publisher
  38. Lin Y, Liu P, Adhikari N, Hall J, Wei L. RIP140 contributes to foam cell formation and atherosclerosis by regulating cholesterol homeostasis in macrophages. J Mol Cell Cardiol. 2015;79:287-94 pubmed publisher
  39. Nagajyothi F, Weiss L, Zhao D, Koba W, Jelicks L, Cui M, et al. High fat diet modulates Trypanosoma cruzi infection associated myocarditis. PLoS Negl Trop Dis. 2014;8:e3118 pubmed publisher
  40. Ramírez C, Lin C, Abdelmohsen K, Goedeke L, Yoon J, Madrigal Matute J, et al. RNA binding protein HuR regulates the expression of ABCA1. J Lipid Res. 2014;55:1066-76 pubmed publisher
  41. Zhao J, Fu Y, Liu C, Shinohara M, Nielsen H, Dong Q, et al. Retinoic acid isomers facilitate apolipoprotein E production and lipidation in astrocytes through the retinoid X receptor/retinoic acid receptor pathway. J Biol Chem. 2014;289:11282-92 pubmed publisher