This is a Validated Antibody Database (VAD) review about rabbit UCP1, based on 8 published articles (read how Labome selects the articles), using UCP1 antibody in all methods. It is aimed to help Labome visitors find the most suited UCP1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
UCP1 synonym: mitochondrial brown fat uncoupling protein 1; UCP 1; solute carrier family 25 member 7; thermogenin; uncoupling protein 1 (mitochondrial, proton carrier)

Invitrogen
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 4c
Invitrogen UCP1 antibody (Thermo Fisher Scientific, PA1-24894) was used in western blot on mouse samples at 1:1000 (fig 4c). EMBO Mol Med (2018) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2b
Invitrogen UCP1 antibody (Pierce, PA1-24894) was used in western blot on mouse samples at 1:1000 (fig 2b). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2e
In order to report that maternal resveratrol intervention protects offspring against high-fat diet-induced obesity, Invitrogen UCP1 antibody (Thermo Scientific, PA1-24894) was used in western blot on mouse samples at 1:1000 (fig 2e). J Physiol (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 1
In order to determine use of coupled and uncoupled energy expenditure pathways by proteomic analysis of human brown adipose tissue, Invitrogen UCP1 antibody (Thermo Fisher, PA1-24894) was used in western blot on human samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
rabbit polyclonal
  • western blot; mouse; 1:1000; fig 1
In order to research how beige and brown adipose tissue are inhibited in the Gq signalling pathway, Invitrogen UCP1 antibody (Thermo Fisher Scientific, PA1-24894) was used in western blot on mouse samples at 1:1000 (fig 1). Nat Commun (2016) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2
In order to elucidate how the microbiota-fat signaling axis affects beige-fat development, Invitrogen UCP1 antibody (Pierce, PA1- 24894) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2). Nat Med (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 3a
In order to examine the effect of Roux-en-Y gastric bypass surgery on natriuretic peptides, Invitrogen UCP1 antibody (Fisher Scientific, PA1-24894) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 3a). Mol Metab (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:100-400
  • western blot; human; 1:100-400
In order to investigate apelin signaling in brown adipocyte tissue, Invitrogen UCP1 antibody (Fisher, PA1-24894) was used in western blot on rat samples at 1:100-400 and in western blot on human samples at 1:100-400. J Biol Chem (2015) ncbi
Articles Reviewed
  1. Bayindir Buchhalter I, Wolff G, Lerch S, Sijmonsma T, Schuster M, Gronych J, et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol Med. 2018;10: pubmed publisher
  2. Song Z, Xiaoli A, Zhang Q, Zhang Y, Yang E, Wang S, et al. Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?. J Biol Chem. 2017;292:8918-8932 pubmed publisher
  3. Zou T, Chen D, Yang Q, Wang B, Zhu M, Nathanielsz P, et al. Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring. J Physiol. 2017;595:1547-1562 pubmed publisher
  4. Müller S, Balaz M, Stefanicka P, Varga L, Amri E, Ukropec J, et al. Proteomic Analysis of Human Brown Adipose Tissue Reveals Utilization of Coupled and Uncoupled Energy Expenditure Pathways. Sci Rep. 2016;6:30030 pubmed publisher
  5. Klepac K, Kilić A, Gnad T, Brown L, Herrmann B, Wilderman A, et al. The Gq signalling pathway inhibits brown and beige adipose tissue. Nat Commun. 2016;7:10895 pubmed publisher
  6. Suárez Zamorano N, Fabbiano S, Chevalier C, Stojanović O, Colin D, Stevanović A, et al. Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nat Med. 2015;21:1497-1501 pubmed publisher
  7. Neinast M, Frank A, Zechner J, Li Q, Vishvanath L, Palmer B, et al. Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning. Mol Metab. 2015;4:427-36 pubmed publisher
  8. Than A, He H, Chua S, Xu D, Sun L, Leow M, et al. Apelin Enhances Brown Adipogenesis and Browning of White Adipocytes. J Biol Chem. 2015;290:14679-91 pubmed publisher