This is a Validated Antibody Database (VAD) review about rabbit SYT1, based on 2 published articles (read how Labome selects the articles), using SYT1 antibody in all methods. It is aimed to help Labome visitors find the most suited SYT1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
SYT1 synonym: synaptotagmin-1; synaptotagmin I

Invitrogen
mouse monoclonal (ASV30)
  • immunoprecipitation; mouse; fig 4b
  • western blot; mouse; fig 3b
In order to study the activity-driven interaction between presenilin 1 and synaptotagmin 1 and links to calcium, amyloid beta, and synapse, Invitrogen SYT1 antibody (Pierce, MA125568) was used in immunoprecipitation on mouse samples (fig 4b) and in western blot on mouse samples (fig 3b). BMC Biol (2016) ncbi
mouse monoclonal (ASV30)
  • immunocytochemistry; rat; fig 3
  • western blot; hamsters; 1:1000; fig 2
In order to assess the interaction of APP with synaptotagmins that promotes A-beta generation, Invitrogen SYT1 antibody (Thermo Fisher, ASV30) was used in immunocytochemistry on rat samples (fig 3) and in western blot on hamsters samples at 1:1000 (fig 2). Mol Neurodegener (2015) ncbi
Articles Reviewed
  1. Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
  2. Gautam V, D Avanzo C, Berezovska O, Tanzi R, Kovacs D. Synaptotagmins interact with APP and promote Aβ generation. Mol Neurodegener. 2015;10:31 pubmed publisher