This is a Validated Antibody Database (VAD) review about pig CASQ1, based on 7 published articles (read how Labome selects the articles), using CASQ1 antibody in all methods. It is aimed to help Labome visitors find the most suited CASQ1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
CASQ1 synonym: calsequestrin-1; calsequestrin 1 (fast-twitch, skeletal muscle); calsquestrin 1

Invitrogen
mouse monoclonal (VIIID12)
  • western blot; mouse; loading ...; fig 5a
In order to report the effects of short- and long-term high-fat diets on fast-twitch skeletal muscles, Invitrogen CASQ1 antibody (Thermo Scientific, MA3-913) was used in western blot on mouse samples (fig 5a). Physiol Rep (2017) ncbi
mouse monoclonal (VIIID12)
  • western blot; mouse; loading ...; fig 2f
In order to report the physiological role of sarcolipin upregulation in muscle myopathy, Invitrogen CASQ1 antibody (Pierce Antibodies, MA3-913) was used in western blot on mouse samples (fig 2f). PLoS ONE (2017) ncbi
mouse monoclonal (VIIID12)
  • western blot; mouse; 1:2000; fig 3
In order to study affects of acute minimization of brown adipose tissue function by increased reliance on muscle based thermogenesis, Invitrogen CASQ1 antibody (Thermo Fisher Scientific, MA3-913) was used in western blot on mouse samples at 1:2000 (fig 3). J Biol Chem (2016) ncbi
mouse monoclonal (VIIID12)
  • western blot; rat; 1:3000; fig 3
In order to study the effects of caloric restriction skeletal muscle contraction, thyroid hormone metabolism, and fiber composition upon refeeding, Invitrogen CASQ1 antibody (Thermo Fisher Scientific, MA3-913) was used in western blot on rat samples at 1:3000 (fig 3). Front Physiol (2015) ncbi
mouse monoclonal (VIIID12)
  • immunohistochemistry; mouse; 1:300
In order to study a missense mutation in the calsequestrin-1 gene discovered in a group of patients with a myopathy, Invitrogen CASQ1 antibody (Thermo Scientific, MA3-913) was used in immunohistochemistry on mouse samples at 1:300. Hum Mutat (2014) ncbi
mouse monoclonal (VIIID12)
  • western blot; human
In order to investigate the abnormalities of calcium handling proteins in skeletal and heart muscle during heart failure, Invitrogen CASQ1 antibody (Pierce, VIIID12) was used in western blot on human samples . J Card Fail (2012) ncbi
mouse monoclonal (VIIID12)
  • western blot; rabbit; 1:2500; fig 8
In order to characterize the interaction between junctophilin 1 and the RyR1 channel complex, Invitrogen CASQ1 antibody (Affinity BioReagents, MA3-913) was used in western blot on rabbit samples at 1:2500 (fig 8). J Biol Chem (2007) ncbi
Articles Reviewed
  1. Eshima H, Tamura Y, Kakehi S, Kurebayashi N, Murayama T, Nakamura K, et al. Long-term, but not short-term high-fat diet induces fiber composition changes and impaired contractile force in mouse fast-twitch skeletal muscle. Physiol Rep. 2017;5: pubmed publisher
  2. Fajardo V, Gamu D, Mitchell A, Bloemberg D, Bombardier E, Chambers P, et al. Sarcolipin deletion exacerbates soleus muscle atrophy and weakness in phospholamban overexpressing mice. PLoS ONE. 2017;12:e0173708 pubmed publisher
  3. Bal N, Maurya S, Singh S, Wehrens X, Periasamy M. Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function. J Biol Chem. 2016;291:17247-57 pubmed publisher
  4. de Andrade P, Neff L, Strosova M, Arsenijevic D, Patthey Vuadens O, Scapozza L, et al. Caloric restriction induces energy-sparing alterations in skeletal muscle contraction, fiber composition and local thyroid hormone metabolism that persist during catch-up fat upon refeeding. Front Physiol. 2015;6:254 pubmed publisher
  5. Rossi D, Vezzani B, Galli L, Paolini C, Toniolo L, Pierantozzi E, et al. A mutation in the CASQ1 gene causes a vacuolar myopathy with accumulation of sarcoplasmic reticulum protein aggregates. Hum Mutat. 2014;35:1163-70 pubmed publisher
  6. Middlekauff H, Vigna C, Verity M, Fonarow G, Horwich T, Hamilton M, et al. Abnormalities of calcium handling proteins in skeletal muscle mirror those of the heart in humans with heart failure: a shared mechanism?. J Card Fail. 2012;18:724-33 pubmed publisher
  7. Phimister A, Lango J, Lee E, Ernst Russell M, Takeshima H, Ma J, et al. Conformation-dependent stability of junctophilin 1 (JP1) and ryanodine receptor type 1 (RyR1) channel complex is mediated by their hyper-reactive thiols. J Biol Chem. 2007;282:8667-77 pubmed