This is a Validated Antibody Database (VAD) review about pig ATP2B2, based on 6 published articles (read how Labome selects the articles), using ATP2B2 antibody in all methods. It is aimed to help Labome visitors find the most suited ATP2B2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ATP2B2 synonym: plasma membrane calcium-transporting ATPase 2; ATPase, Ca++ transporting, plasma membrane 2

Invitrogen
rabbit polyclonal
  • immunocytochemistry; human; loading ...
  • western blot; human; loading ...; fig 3a
In order to explore how HER2 signaling contributes to the formation and maintenance of membrane protrusions, Invitrogen ATP2B2 antibody (Thermo Scientific, PA1-915) was used in immunocytochemistry on human samples and in western blot on human samples (fig 3a). PLoS ONE (2017) ncbi
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 2i
  • immunocytochemistry; human; loading ...; fig 2b
  • western blot; human; loading ...; fig 2i
In order to show that NHERF1 and PMCA2 modulate HER2 signaling and membrane retention in breast cancers, Invitrogen ATP2B2 antibody (Thermo Scientific, PA1-915) was used in immunoprecipitation on human samples (fig 2i), in immunocytochemistry on human samples (fig 2b) and in western blot on human samples (fig 2i). J Biol Chem (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
In order to propose that PMCA2 is not required for medial nucleus of the trapezoid body neuron survival and investigate other factors that contribute to their survival, Invitrogen ATP2B2 antibody (Affinity Bioreagents, PA1-915) was used in immunohistochemistry - frozen section on mouse samples (fig 1a). J Neurophysiol (2017) ncbi
rabbit polyclonal
  • western blot; mouse; loading ...; fig 4e
In order to investigate how sphingomyelin influence neural pathology in a mouse model of Niemann-Pick disease type A, Invitrogen ATP2B2 antibody (ThermoFisher Scientific, PA1-915) was used in western blot on mouse samples (fig 4e). Mol Psychiatry (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:300; fig 1
In order to investigate the regulation of breast cancer cell proliferation and sensitivity to doxorubicin through the calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2), Invitrogen ATP2B2 antibody (Thermo Scientific, PA1-915) was used in immunohistochemistry - paraffin section on human samples at 1:300 (fig 1). Sci Rep (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 1
In order to study the interactions between PMCA2 and HER2 in breast cancer cells, Invitrogen ATP2B2 antibody (Thermo Scientific, PA1-915) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 1). Proc Natl Acad Sci U S A (2016) ncbi
Articles Reviewed
  1. Jeong J, Kim W, Kim L, VanHouten J, Wysolmerski J. HER2 signaling regulates HER2 localization and membrane retention. PLoS ONE. 2017;12:e0174849 pubmed publisher
  2. Jeong J, VanHouten J, Kim W, Dann P, Sullivan C, Choi J, et al. The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2. J Biol Chem. 2017;292:6555-6568 pubmed publisher
  3. Weatherstone J, Kopp Scheinpflug C, Pilati N, Wang Y, Forsythe I, Rubel E, et al. Maintenance of neuronal size gradient in MNTB requires sound-evoked activity. J Neurophysiol. 2017;117:756-766 pubmed publisher
  4. Pérez Cañamás A, Benvegnù S, Rueda C, Rábano A, Satrústegui J, Ledesma M. Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann-Pick disease. Mol Psychiatry. 2017;22:711-723 pubmed publisher
  5. Peters A, Milevskiy M, Lee W, Curry M, Smart C, Saunus J, et al. The calcium pump plasma membrane Ca(2+)-ATPase 2 (PMCA2) regulates breast cancer cell proliferation and sensitivity to doxorubicin. Sci Rep. 2016;6:25505 pubmed publisher
  6. Jeong J, VanHouten J, Dann P, Kim W, Sullivan C, Yu H, et al. PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016;113:E282-90 pubmed publisher