This is a Validated Antibody Database (VAD) review about pig APP, based on 45 published articles (read how Labome selects the articles), using APP antibody in all methods. It is aimed to help Labome visitors find the most suited APP antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
APP synonym: amyloid-beta A4 protein; amyloid beta A4 protein; ABPP; alzheimer disease amyloid A4 protein homolog; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid precursor protein; beta-amyloid precursor protein
Invitrogen
rabbit polyclonal (CT695) |
| In order to characterize gyrencephalic swine brains exposed to true open field blasts, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on pig samples at 1:250 (fig 1a). PLoS ONE (2017) ncbi |
rabbit polyclonal (CT695) |
| In order to describe functional and structural pathology-to-network signatures in the brain after cuprizone treatment, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples (fig 2e). Neuroimage (2017) ncbi |
rabbit polyclonal (CT695) |
| In order to suggest that loss of the Wnt signaling pathway may contribute to Alzheimer's disease pathogenesis, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples (fig 3b). J Neurochem (2016) ncbi |
rabbit polyclonal (CT695) |
| In order to show that Egr-1 plays role in BACE-1 activation, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples (fig 3a). J Biol Chem (2016) ncbi |
rabbit polyclonal (CT695) |
| In order to characterize organelles that bind microtubules in an ATP dependent manner by studying the amyloid precursor protein of Alzheimer's disease clusters at the organelle/microtubule interface, Invitrogen APP antibody (Invitrogen, 51-C2700) was used in immunocytochemistry on longfin inshore squid samples (fig 1). PLoS ONE (2016) ncbi |
rabbit polyclonal (CT695) |
| In order to assess the deletion of Ccr2 and cavity size and tau pathology after mild traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on mouse samples (fig 3). J Neuroinflammation (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to assess Losartan treatment on experimental glaucoma, Invitrogen APP antibody (Novex by Life Technologies, 512700) was used in immunohistochemistry on mouse samples at 0.75 ug/ul (fig 2). PLoS ONE (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to determine the relationship between injured axons after mild traumatic brain injury in pigs and microglia processes, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry on pig samples at 1:700 (fig 6). J Neuroinflammation (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to elucidate the mechanisms by which increased LMNB1 levels cause autosomal dominant leukodystrophy, Invitrogen APP antibody (Invitrogen, 512700) was used in immunohistochemistry - frozen section on mouse samples (fig 3). J Neurosci (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to show that IDN5706 promotes iAPP degradation by activating Atg5-dependent autophagy, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples . PLoS ONE (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to describe the development of a closed-body model of spinal cord injury in mice, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on mouse samples . Exp Neurol (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to discuss the limitations assessing axonal injury by microscopy, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 6) and in immunohistochemistry on mouse samples at 1:50 (fig 5). J Neurosci Methods (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to investigate the contribution of TREM2 to microglia function in vivo, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunocytochemistry on mouse samples at 1:100 (fig 2). Acta Neuropathol (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to characterize axonal injury over time, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples at 1:700. Acta Neuropathol (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to examine the role of the monoaminergic system in mild blast-induced traumatic brain injury, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on rat samples at 1:400. J Neurotrauma (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to identify the relation between fragile X mental retardation protein and Alzheimer disease, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples at 1:500. Front Genet (2014) ncbi |
rabbit polyclonal (CT695) |
| In order to report that Kal9 and Kal12 mediate dendritic maturation in early development, Invitrogen APP antibody (Life Technologies, 51-2700) was used in western blot on rat samples (fig 1). Cereb Cortex (2015) ncbi |
rabbit polyclonal (CT695) |
| In order to discuss the effects of BMS-869780, a gamma secretase inhibitor, in several animal models, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on human samples . Int J Alzheimers Dis (2014) ncbi |
rabbit polyclonal (CT695) |
| In order to assess if subischemic levels of elevated intracranial pressure without hematoma/contusion contribute to increased morbidity/mortality, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - free floating section on rat samples at 1:1000. J Cereb Blood Flow Metab (2014) ncbi |
rabbit polyclonal (CT695) |
| In order to study the contribution of microglia to axon degeneration after repetitive closed-skull traumatic brain injury using CD11b-thymidine kinase mice, Invitrogen APP antibody (Invitrogen, 512700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Neurotrauma (2014) ncbi |
rabbit polyclonal (CT695) |
| In order to assess temporal and spatial onset of the reactive glia response in a clinically relevant form of Pelizaeus-Merzbacher disease, Invitrogen APP antibody (Life Technologies, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:2000 (fig 6). J Neuroinflammation (2013) ncbi |
rabbit polyclonal (CT695) |
| In order to study Abeta agggregation and oligomerization induced in a murine model of Alzheimer's disease by experimental traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:1000. J Neurotrauma (2014) ncbi |
rabbit polyclonal (CT695) |
| In order to assess myelin loss and oligodendrocyte death following traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51 2700) was used in western blot on rat samples (fig 3). Eur J Neurosci (2013) ncbi |
rabbit polyclonal (CT695) |
| In order to study the neuronal somatic and axonal damage that occurs during elevated intracranial pressure, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on rat samples at 1:1000 (fig 2). J Cereb Blood Flow Metab (2012) ncbi |
rabbit polyclonal (CT695) |
| In order to investigate diffuse axonal injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on rat samples (fig 4). J Trauma Acute Care Surg (2012) ncbi |
rabbit polyclonal (CT695) |
| In order to perform a time course to study impaired axoplasmic transport and neurofilament compaction, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1 ug/ml (fig 6). Brain Res (2012) ncbi |
rabbit polyclonal (CT695) |
| In order to discuss the use of helmets to prevent traumatic brain injury, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1:200 (fig 4). Neurosurgery (2012) ncbi |
rabbit polyclonal (CT695) |
| In order to study traumatic axonal injury in rats, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1 ug/ml (fig 7, 8). J Neurotrauma (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to characterize a new rat model of diffuse brain injury in the sagittal plane, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on rat samples at 1:100. Front Neurol (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to characterize a rodent model of direct cranial blast injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - frozen section on rat samples at 1:200 (fig 7). J Neurotrauma (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to investigate the effects of blast injury on the parenchymatous organs of mice, Invitrogen APP antibody (Zymed , 51-2700) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 3). J Neuropathol Exp Neurol (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to examine the oligodendrogenic potential of different human fetal forebrain regions during the first trimester of gestation, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on human samples at 1:100 (fig 5). Brain (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to investigate the effects of using either a rounded- or a flat-tip impactor to apply controlled cortical impact injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry - free floating section on mouse samples at 1:100. J Neurotrauma (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to assess the benefits of O3FA supplementation following diffuse axonal injury in rats, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1:200 (fig 1). J Neurosurg (2011) ncbi |
rabbit polyclonal (CT695) |
| In order to assess the benefits of DHA treatment following diffuse axonal injury in rats, Invitrogen APP antibody (Zymed, 51-2700) was used in immunohistochemistry on rat samples at 1:200 (fig 2). J Neurotrauma (2010) ncbi |
rabbit polyclonal (CT695) |
| In order to elucidate the mechanism of calpain during Alzheimer's disease progression, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples at 1:1000 (fig 5). J Biol Chem (2010) ncbi |
rabbit polyclonal (CT695) |
| In order to test if proprotein convertase subtilisin/kexin type 9 modulates the levels of low-density lipoprotein receptor and other membrane-bound proteins in the adult mouse brain, Invitrogen APP antibody (Invitrogen, 51-2700) was used in western blot on mouse samples at 0.5 ug/ml. J Lipid Res (2010) ncbi |
rabbit polyclonal (CT695) |
| In order to assess the effects of acute treatment with minocycline on traumatic brain injury, Invitrogen APP antibody (Invitrogen, 51-2700) was used in immunohistochemistry on mouse samples at 1:1000 (fig 1). J Neurotrauma (2010) ncbi |
rabbit polyclonal (CT695) | In order to investigate the regulatory link between beta-amyloid precursor protein and dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A in Down syndrome brains, Invitrogen APP antibody (Zymed Laboratories, 51-2700) was used . J Neurochem (2008) ncbi | |
rabbit polyclonal (CT695) | In order to discuss features present in feline myopathy, Invitrogen APP antibody (Zymed, 51?C2700) was used . Acta Neuropathol (2007) ncbi | |
rabbit polyclonal (CT695) | In order to examine the interaction between amyloid precursor protein and ShcA/Grb2, Invitrogen APP antibody (Zymed Laboratories, 51-2700) was used . Ann N Y Acad Sci (2006) ncbi | |
rabbit polyclonal (CT695) | In order to propose that amyloid precursor protein and presenilin1 are part of a common signaling pathway that regulates ERK1,2 and the cell cycle, Invitrogen APP antibody (Zymed, 51-2700) was used . J Biol Chem (2007) ncbi | |
rabbit polyclonal (CT695) | In order to elucidate the molecular mechanism that links Alzheimer disease and fragile X syndrome, Invitrogen APP antibody (Zymed, 51-2700) was used . PLoS Biol (2007) ncbi | |
rabbit polyclonal (CT695) | In order to develop and characterize a tissue culture model of traumatic brain injury, Invitrogen APP antibody (Zymed, 51-2700) was used . Stapp Car Crash J (2003) ncbi | |
rabbit polyclonal (CT695) | In order to develop a new weight-drop head-injury apparatus and assess the treated rats, Invitrogen APP antibody (Zymed, 51-2700) was used . J Neurosci Methods (2006) ncbi |
Articles Reviewed
- Qin X, Wang Y, Paudel H. Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of ?-Secretase 1 (BACE-1) in the Brain. J Biol Chem. 2016;291:22276-22287 pubmed
- Lafrenaye A, McGinn M, Povlishock J. Increased intracranial pressure after diffuse traumatic brain injury exacerbates neuronal somatic membrane poration but not axonal injury: evidence for primary intracranial pressure-induced neuronal perturbation. J Cereb Blood Flow Metab. 2012;32:1919-32 pubmed publisher
- Jia X, Cong B, Wang S, Dong L, Ma C, Li Y. Secondary damage caused by CD11b+ microglia following diffuse axonal injury in rats. J Trauma Acute Care Surg. 2012;73:1168-74 pubmed
- Homsi S, Piaggio T, Croci N, Noble F, Plotkine M, Marchand Leroux C, et al. Blockade of acute microglial activation by minocycline promotes neuroprotection and reduces locomotor hyperactivity after closed head injury in mice: a twelve-week follow-up study. J Neurotrauma. 2010;27:911-21 pubmed publisher
- Ryoo S, Cho H, Lee H, Jeong H, Radnaabazar C, Kim Y, et al. Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease. J Neurochem. 2008;104:1333-44 pubmed
- Shelton G, Sturges B, Lyons L, Williams D, Aleman M, Jiang Y, et al. Myopathy with tubulin-reactive inclusions in two cats. Acta Neuropathol. 2007;114:537-42 pubmed
- Venezia V, Nizzari M, Repetto E, Violani E, Corsaro A, Thellung S, et al. Amyloid precursor protein modulates ERK-1 and -2 signaling. Ann N Y Acad Sci. 2006;1090:455-65 pubmed
- Nizzari M, Venezia V, Repetto E, Caorsi V, Magrassi R, Gagliani M, et al. Amyloid precursor protein and Presenilin1 interact with the adaptor GRB2 and modulate ERK 1,2 signaling. J Biol Chem. 2007;282:13833-44 pubmed
- Westmark C, Malter J. FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS Biol. 2007;5:e52 pubmed
- Morrison B, Cater H, Wang C, Thomas F, Hung C, Ateshian G, et al. A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading. Stapp Car Crash J. 2003;47:93-105 pubmed
- Pal J, Toth Z, Farkas O, Kellenyi L, Doczi T, Gallyas F. Selective induction of ultrastructural (neurofilament) compaction in axons by means of a new head-injury apparatus. J Neurosci Methods. 2006;153:283-9 pubmed
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