This is a Validated Antibody Database (VAD) review about mouse klotho, based on 3 published articles (read how Labome selects the articles), using klotho antibody in all methods. It is aimed to help Labome visitors find the most suited klotho antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
klotho synonym: alpha-kl; klotho; secreted form of Klotho protein

Abcam
rabbit monoclonal (EPR6856)
  • immunohistochemistry - paraffin section; human; 1:20; loading ...; fig 5a
  • immunocytochemistry; human; 1:20; fig 6a
  • western blot; human; 1:500; fig 6c
Abcam klotho antibody (Abcam, ab181373) was used in immunohistochemistry - paraffin section on human samples at 1:20 (fig 5a), in immunocytochemistry on human samples at 1:20 (fig 6a) and in western blot on human samples at 1:500 (fig 6c). Arthritis Res Ther (2017) ncbi
Invitrogen
rabbit polyclonal
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 4c
In order to show that ROS-induced DNA damage reduces metabolic activity, inhibits proliferation, and induces cell cycle arrest followed by activation of p16-, p21-, and p27- mediated DNA damage response pathways, premature senescence, and apoptosis induction, Invitrogen klotho antibody (Thermo Scientific, PA5-21078) was used in immunocytochemistry on human samples (fig 4b) and in western blot on human samples (fig 4c). Exp Cell Res (2017) ncbi
R&D Systems
rat monoclonal (236214)
  • immunohistochemistry - free floating section; mouse; 1:500
  • western blot; mouse; 1:500
R&D Systems klotho antibody (R&D, MAB1819) was used in immunohistochemistry - free floating section on mouse samples at 1:500 and in western blot on mouse samples at 1:500. Sci Rep (2015) ncbi
Articles Reviewed
  1. Mazzotta C, Manetti M, Rosa I, Romano E, Blagojevic J, Bellando Randone S, et al. Proangiogenic effects of soluble ?-Klotho on systemic sclerosis dermal microvascular endothelial cells. Arthritis Res Ther. 2017;19:27 pubmed publisher
  2. Mytych J, Wos I, Solek P, Koziorowski M. Protective role of klotho protein on epithelial cells upon co-culture with activated or senescent monocytes. Exp Cell Res. 2017;350:358-367 pubmed publisher
  3. Xin Y, Yuan B, Yu B, Wang Y, Wu J, Zhou W, et al. Tet1-mediated DNA demethylation regulates neuronal cell death induced by oxidative stress. Sci Rep. 2015;5:7645 pubmed publisher