This is a Validated Antibody Database (VAD) review about mouse claudin 7, based on 33 published articles (read how Labome selects the articles), using claudin 7 antibody in all methods. It is aimed to help Labome visitors find the most suited claudin 7 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Abcam
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 6a
Abcam claudin 7 antibody (Abcam, ab27487) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 6a). World J Gastroenterol (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 2.5 ug/ml; loading ...
  • western blot; mouse; 0.5 ug/ml; loading ...; fig 5a
Invitrogen claudin 7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry - paraffin section on mouse samples at 2.5 ug/ml and in western blot on mouse samples at 0.5 ug/ml (fig 5a). Biol Open (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s7
Invitrogen claudin 7 antibody (Thermo-Fisher, 349100) was used in western blot on human samples (fig s7). Cells (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 4d
  • western blot; mouse; 1:20,000; loading ...; fig 4a
Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4d) and in western blot on mouse samples at 1:20,000 (fig 4a). Am J Physiol Gastrointest Liver Physiol (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:100; loading ...; fig s7c
Invitrogen claudin 7 antibody (Thermo Fisher Scientific, 34-9100) was used in immunocytochemistry on human samples at 1:100 (fig s7c). Proc Natl Acad Sci U S A (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; dogs; fig 2
  • western blot; dogs; fig 2
In order to study the role of claudin-4 in tight junctions in MDCK cells, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used in immunocytochemistry on dogs samples (fig 2) and in western blot on dogs samples (fig 2). PLoS ONE (2017) ncbi
domestic rabbit polyclonal
  • western blot; dogs; 1:250; loading ...; fig 2d
In order to investigate that role of zonula occludens-2 in Rho protein activation and epithelial development, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used in western blot on dogs samples at 1:250 (fig 2d). Biochim Biophys Acta Mol Cell Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 6c
In order to test if HAI-2, matriptase, EpCAM, and claudin-7 are functionally linked in the intestine, Invitrogen claudin 7 antibody (Life Technologies, 34-9100) was used in western blot on human samples (fig 6c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1e
  • immunocytochemistry; human; 1:200; loading ...; fig 2h
  • western blot; human; 1:1000; loading ...; fig s2a
In order to show that the absence of EpCAM in enterocytes results in an aberrant apical domain, Invitrogen claudin 7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1e), in immunocytochemistry on human samples at 1:200 (fig 2h) and in western blot on human samples at 1:1000 (fig s2a). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • flow cytometry; human; 1:100; loading ...; fig 3a
In order to ascertain how claudin-6 is associated with MMP-2 activation and cell invasiveness, Invitrogen claudin 7 antibody (Invitrogen, 349100) was used in flow cytometry on human samples at 1:100 (fig 3a). Exp Cell Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6e
  • western blot; mouse; 1:1000; loading ...; fig 6a
In order to examine the role of Salmonella AvrA during infection, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used in western blot on human samples at 1:1000 (fig 2a), in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6e) and in western blot on mouse samples at 1:1000 (fig 6a). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 3
In order to assess claudin-5 expression in ependymoma, Invitrogen claudin 7 antibody (Zymed, 34-9100) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 3). Pathol Oncol Res (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 5
In order to assess the transiently formed junctional nexuses during post-natal mammary gland development by E-cadherins, connexins, beta-catenin, and claudin-7, Invitrogen claudin 7 antibody (Life Technologies, 34-9100) was used in western blot on mouse samples at 1:1000 (fig 5). Dev Biol (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2
In order to elucidate regulation of E-cadherin and CD24 by determination of cell fate transition and impeding tumor initiation and progression in breast cancer via HOXA5, Invitrogen claudin 7 antibody (Thermo Fisher Scientific, 34-9100) was used in western blot on human samples (fig 2). Oncogene (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; fig 1
In order to utilize a microwave antigen retrieval method by using two heating steps for enhanced immunostaining on tissue sections that are aldehyde-fixed and paraffin-embedded, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used in immunohistochemistry - paraffin section on mouse samples (fig 1). Histochem Cell Biol (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; fig 4
  • western blot; human; fig 1c
In order to elucidate the contribution of SPRY2 to colon cancer, Invitrogen claudin 7 antibody (Life Technologies, 34-9100) was used in immunohistochemistry on human samples (fig 4) and in western blot on human samples (fig 1c). Oncogene (2016) ncbi
domestic rabbit polyclonal
In order to characterize TALEN-mediated claudin-2 knockout in MDCK cells, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used . PLoS ONE (2015) ncbi
mouse monoclonal (5D10F3)
  • western blot; human
In order to investigate the effect of homoharringtonine on intestinal epithelial permeability and its mechanism, Invitrogen claudin 7 antibody (Invitrogen, 37-4800) was used in western blot on human samples . Eur J Pharm Biopharm (2015) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry; human; 1:50; fig 1
In order to correlate expression of claudins with clinical outcomes of triple-negative breast cancer, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunohistochemistry on human samples at 1:50 (fig 1). PLoS ONE (2014) ncbi
domestic rabbit polyclonal
In order to study the involvement of autocrine CSF1R signaling in claudin-low breast tumor cells, Invitrogen claudin 7 antibody (Invitrogen, 34-9100) was used . Oncogene (2015) ncbi
mouse monoclonal (5D10F3)
  • western blot; human; fig 11
In order to develop an in vitro model of gelatinous drop-like corneal dystrophy using a new cell line deficient in tumor-associated calcium signal transducer 2, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in western blot on human samples (fig 11). Trans Am Ophthalmol Soc (2012) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry - paraffin section; human; 1:1000; fig 1
In order to examine the complexity of the invasive front of colon carcinoma, Invitrogen claudin 7 antibody (Zymed, clone 5D10F3) was used in immunohistochemistry - paraffin section on human samples at 1:1000 (fig 1). Int J Biomed Sci (2010) ncbi
mouse monoclonal (5D10F3)
  • western blot; human; 1:500; fig S4
In order to identify elements of intestinal polarity regulated by Rab25, Invitrogen claudin 7 antibody (Zymed, 37-4800) was used in western blot on human samples at 1:500 (fig S4). Mol Biol Cell (2013) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry; human; fig 4
In order to explore how to distinguish of renal oncocytoma from chromophobe renal cell carcinoma, Invitrogen claudin 7 antibody (Invitrogen, 5D10F3) was used in immunohistochemistry on human samples (fig 4). Med Mol Morphol (2012) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry; human; fig 3
In order to identify and describe Franceschetti corneal dystrophy, Invitrogen claudin 7 antibody (Invitrogen, 5D10F3) was used in immunohistochemistry on human samples (fig 3). Am J Ophthalmol (2012) ncbi
mouse monoclonal (5D10F3)
  • immunocytochemistry; human; fig 5
In order to investigate the contribution of CA125/MUC16 to metastasis of epithelial ovarian cancer, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunocytochemistry on human samples (fig 5). Br J Cancer (2011) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry - paraffin section; human; 1:400; fig 3
In order to discuss how to distinguish renal oncocytoma from the eosinophilic variant of chromophobe, and papillary and clear cell renal cell carcinoma, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 3). Histopathology (2011) ncbi
mouse monoclonal (5D10F3)
  • immunocytochemistry; human; fig 5
  • immunohistochemistry; human; fig 2
  • western blot; human; fig 2
In order to determine the relationship between the TACSTD2 gene and epithelial barrier function, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunocytochemistry on human samples (fig 5), in immunohistochemistry on human samples (fig 2) and in western blot on human samples (fig 2). Am J Pathol (2010) ncbi
mouse monoclonal (5D10F3)
  • immunohistochemistry - paraffin section; human; 1:50; fig 4a
  • immunocytochemistry; human; fig 4h
In order to explore the use of Claudin-7 as a biomarker for ovarian adenocarcinoma, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 4a) and in immunocytochemistry on human samples (fig 4h). Int J Gynecol Cancer (2008) ncbi
mouse monoclonal (5D10F3)
  • immunocytochemistry; human; 1:200; fig 1
In order to measure Claudin-7 expression in smears from breast carcinomas and correlate expression with grading, nodal status, locoregional and distant metastases, and the cellular cohesion, Invitrogen claudin 7 antibody (Zymed, 5D10F3) was used in immunocytochemistry on human samples at 1:200 (fig 1). Cytopathology (2005) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1d
  • western blot; mouse; 1:1000; loading ...; fig 1e
Abcam claudin 7 antibody (abcam, ab27487) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1d) and in western blot on mouse samples at 1:1000 (fig 1e). Oncoimmunology (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 6a
Abcam claudin 7 antibody (Abcam, ab27487) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 6a). World J Gastroenterol (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 5a
In order to test if Dub3 contributes to Snail1 stability in cancer cells, Abcam claudin 7 antibody (abcam, ab27487) was used in western blot on human samples at 1:1000 (fig 5a). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:200; fig s1
In order to utilize ovarian cancer xenograft models to study dynamic modulation of phosphoprotein expression, Abcam claudin 7 antibody (Abcam, AB27487) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig s1). BMC Cancer (2016) ncbi
Articles Reviewed
  1. Szabo R, Ward J, Artunc F, Bugge T. EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice. Biol Open. 2022;11: pubmed publisher
  2. Naydenov N, Lechuga S, Zalavadia A, Mukherjee P, Gordon I, Skvasik D, et al. P-Cadherin Regulates Intestinal Epithelial Cell Migration and Mucosal Repair, but Is Dispensable for Colitis Associated Colon Cancer. Cells. 2022;11: pubmed publisher
  3. Wang K, Ding Y, Xu C, Hao M, Li H, Ding L. Cldn-7 deficiency promotes experimental colitis and associated carcinogenesis by regulating intestinal epithelial integrity. Oncoimmunology. 2021;10:1923910 pubmed publisher
  4. Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al. Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. Am J Physiol Gastrointest Liver Physiol. 2021;320:G936-G957 pubmed publisher
  5. Wijshake T, Zou Z, Chen B, Zhong L, Xiao G, Xie Y, et al. Tumor-suppressor function of Beclin 1 in breast cancer cells requires E-cadherin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  6. Xu C, Wang K, Ding Y, Li W, Ding L. Claudin-7 gene knockout causes destruction of intestinal structure and animal death in mice. World J Gastroenterol. 2019;25:584-599 pubmed publisher
  7. Tokuda S, Hirai T, Furuse M. Claudin-4 knockout by TALEN-mediated gene targeting in MDCK cells: Claudin-4 is dispensable for the permeability properties of tight junctions in wild-type MDCK cells. PLoS ONE. 2017;12:e0182521 pubmed publisher
  8. Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher
  9. Wu Y, Wang Y, Lin Y, Liu Y, Wang Y, Jia J, et al. Dub3 inhibition suppresses breast cancer invasion and metastasis by promoting Snail1 degradation. Nat Commun. 2017;8:14228 pubmed publisher
  10. Wu C, Feng X, Lu M, Morimura S, Udey M. Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis. J Clin Invest. 2017;127:623-634 pubmed publisher
  11. Salomon J, Gaston C, Magescas J, Duvauchelle B, Canioni D, Sengmanivong L, et al. Contractile forces at tricellular contacts modulate epithelial organization and monolayer integrity. Nat Commun. 2017;8:13998 pubmed publisher
  12. Torres Martínez A, Gallardo Vera J, Lara Holguin A, Montano L, Rendón Huerta E. Claudin-6 enhances cell invasiveness through claudin-1 in AGS human adenocarcinoma gastric cancer cells. Exp Cell Res. 2017;350:226-235 pubmed publisher
  13. Lin Z, Zhang Y, Xia Y, Xu X, Jiao X, Sun J. Salmonella enteritidis Effector AvrA Stabilizes Intestinal Tight Junctions via the JNK Pathway. J Biol Chem. 2016;291:26837-26849 pubmed publisher
  14. Virág J, Haberler C, Baksa G, Piurko V, Hegedûs Z, Reiniger L, et al. Region Specific Differences of Claudin-5 Expression in Pediatric Intracranial Ependymomas: Potential Prognostic Role in Supratentorial Cases. Pathol Oncol Res. 2017;23:245-252 pubmed publisher
  15. Dianati E, Poiraud J, Weber Ouellette A, Plante I. Connexins, E-cadherin, Claudin-7 and ?-catenin transiently form junctional nexuses during the post-natal mammary gland development. Dev Biol. 2016;416:52-68 pubmed publisher
  16. Teo W, Merino V, Cho S, Korangath P, Liang X, Wu R, et al. HOXA5 determines cell fate transition and impedes tumor initiation and progression in breast cancer through regulation of E-cadherin and CD24. Oncogene. 2016;35:5539-5551 pubmed publisher
  17. Gu L, Cong J, Zhang J, Tian Y, Zhai X. A microwave antigen retrieval method using two heating steps for enhanced immunostaining on aldehyde-fixed paraffin-embedded tissue sections. Histochem Cell Biol. 2016;145:675-80 pubmed publisher
  18. Koussounadis A, Langdon S, Um I, Kay C, Francis K, Harrison D, et al. Dynamic modulation of phosphoprotein expression in ovarian cancer xenograft models. BMC Cancer. 2016;16:205 pubmed publisher
  19. Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed publisher
  20. Tokuda S, Furuse M. Claudin-2 knockout by TALEN-mediated gene targeting in MDCK cells: claudin-2 independently determines the leaky property of tight junctions in MDCK cells. PLoS ONE. 2015;10:e0119869 pubmed publisher
  21. Watari A, Hashegawa M, Yagi K, Kondoh M. Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers. Eur J Pharm Biopharm. 2015;89:232-8 pubmed publisher
  22. Ma F, Ding X, Fan Y, Ying J, Zheng S, Lu N, et al. A CLDN1-negative phenotype predicts poor prognosis in triple-negative breast cancer. PLoS ONE. 2014;9:e112765 pubmed publisher
  23. Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, et al. Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGF? in claudin-low breast tumor cells. Oncogene. 2015;34:2721-31 pubmed publisher
  24. Kinoshita S, Kawasaki S, Kitazawa K, Shinomiya K. Establishment of a human conjunctival epithelial cell line lacking the functional TACSTD2 gene (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc. 2012;110:166-77 pubmed
  25. Victoria H, Henrik E, Lennart B, Lennart F. Claudin 1 and Claudin 7 Gene Polymorphisms and Protein Derangement are Unrelated to the Growth Pattern and Tumor Volume of Colon Carcinoma. Int J Biomed Sci. 2010;6:96-102 pubmed
  26. Krishnan M, Lapierre L, Knowles B, Goldenring J. Rab25 regulates integrin expression in polarized colonic epithelial cells. Mol Biol Cell. 2013;24:818-31 pubmed publisher
  27. Ohe C, Kuroda N, Takasu K, Senzaki H, Shikata N, Yamaguchi T, et al. Utility of immunohistochemical analysis of KAI1, epithelial-specific antigen, and epithelial-related antigen for distinction of chromophobe renal cell carcinoma, an eosinophilic variant from renal oncocytoma. Med Mol Morphol. 2012;45:98-104 pubmed publisher
  28. Lisch W, Bron A, Munier F, Schorderet D, Tiab L, Lange C, et al. Franceschetti hereditary recurrent corneal erosion. Am J Ophthalmol. 2012;153:1073-81.e4 pubmed publisher
  29. Comamala M, Pinard M, Theriault C, Matte I, Albert A, Boivin M, et al. Downregulation of cell surface CA125/MUC16 induces epithelial-to-mesenchymal transition and restores EGFR signalling in NIH:OVCAR3 ovarian carcinoma cells. Br J Cancer. 2011;104:989-99 pubmed publisher
  30. Carvalho J, Wasco M, Kunju L, Thomas D, Shah R. Cluster analysis of immunohistochemical profiles delineates CK7, vimentin, S100A1 and C-kit (CD117) as an optimal panel in the differential diagnosis of renal oncocytoma from its mimics. Histopathology. 2011;58:169-79 pubmed publisher
  31. Nakatsukasa M, Kawasaki S, Yamasaki K, Fukuoka H, Matsuda A, Tsujikawa M, et al. Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy. Am J Pathol. 2010;177:1344-55 pubmed publisher
  32. Tassi R, Bignotti E, Falchetti M, Ravanini M, Calza S, Ravaggi A, et al. Claudin-7 expression in human epithelial ovarian cancer. Int J Gynecol Cancer. 2008;18:1262-71 pubmed publisher
  33. Sauer T, Pedersen M, Ebeltoft K, Naess O. Reduced expression of Claudin-7 in fine needle aspirates from breast carcinomas correlate with grading and metastatic disease. Cytopathology. 2005;16:193-8 pubmed