This is a Validated Antibody Database (VAD) review about mouse ZO 2, based on 43 published articles (read how Labome selects the articles), using ZO 2 antibody in all methods. It is aimed to help Labome visitors find the most suited ZO 2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
ZO 2 synonym: ZO-2; tight junction protein ZO-2; Tight junction protein ZO-2 (Zonula occludens 2 protein) (Zona occludens 2 protein) (Tight junction protein 2); zona occludens protein 2; zonula occludens protein 2
Knockout validation
Invitrogen rabbit polyclonal |
| In order to visualize the interaction of claudin, ZO-1 and actin in epithelial tight juntions., Invitrogen ZO 2 antibody (GE Healthcare, 38-9100) was used in western blot knockout validation on rat samples (fig 4d). Mol Biol Cell (2017) ncbi |
Invitrogen
rabbit polyclonal |
| Invitrogen ZO 2 antibody (ThermoFisher, 711400) was used in western blot on human samples at 1:1000 (fig 3s2a). elife (2019) ncbi |
rabbit polyclonal |
| In order to investigate that role of zonula occludens-2 in Rho protein activation and epithelial development, Invitrogen ZO 2 antibody (Invitrogen, 711400) was used in proximity ligation assay on dog samples at 1:100, in immunocytochemistry on dog samples at 1:100 (fig 1a) and in western blot on dog samples at 1:1000 (fig 1a). Biochim Biophys Acta Mol Cell Res (2017) ncbi |
rabbit polyclonal |
| In order to visualize the interaction of claudin, ZO-1 and actin in epithelial tight juntions., Invitrogen ZO 2 antibody (GE Healthcare, 38-9100) was used in western blot knockout validation on rat samples (fig 4d). Mol Biol Cell (2017) ncbi |
rabbit polyclonal |
| In order to assess induction of renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway due to ZO-2 silencing, Invitrogen ZO 2 antibody (Invitrogen, 711400) was used in immunocytochemistry on dog samples (fig 1A). Mol Biol Cell (2016) ncbi |
rabbit polyclonal |
| In order to characterize two clones from triple negative breast MDA-MB-231 cancer cells, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on human samples at 1:50 (fig 2b) and in western blot on human samples at 1:1000 (fig 2a). Exp Cell Res (2015) ncbi |
rabbit polyclonal |
| In order to describe a miRNA-dependent mechanism of Dicer in reestablishing the barrier function of the skin post-wounding, Invitrogen ZO 2 antibody (Invitrogen, 38-9,100) was used in immunohistochemistry - frozen section on mouse samples at 1:200. Mol Ther (2015) ncbi |
rabbit polyclonal |
| In order to characterize TALEN-mediated claudin-2 knockout in MDCK cells, Invitrogen ZO 2 antibody (Invitrogen, 38-9100) was used in immunocytochemistry on dog samples . PLoS ONE (2015) ncbi |
rabbit polyclonal |
| In order to investigate the effect of homoharringtonine on intestinal epithelial permeability and its mechanism, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in western blot on human samples . Eur J Pharm Biopharm (2015) ncbi |
rabbit polyclonal |
| In order to study the contribution of ZO-1, -2, and -3 on collecting duct cell proliferation, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry - paraffin section on rat samples at 1:500 (fig 7), in immunocytochemistry on mouse samples at 1:500 (fig 3) and in western blot on mouse samples at 1:500 (fig 6). Cell Cycle (2014) ncbi |
rabbit polyclonal |
| In order to study the role of down syndrome cell adhesion molecule during mice retina development, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on mouse samples at 1:400. Mol Vis (2014) ncbi |
rabbit polyclonal |
| In order to characterize the TALEN-mediated ZO-1 knockout in MDCK cells, Invitrogen ZO 2 antibody (Invitrogen, 38-9100) was used in immunocytochemistry on dog samples and in western blot on dog samples . PLoS ONE (2014) ncbi |
rabbit polyclonal |
| In order to analyze the barrier properties of mouse brain endothelial cells and stabilizing adherens junctions due to heparan sulfate proteoglycan agrin, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunocytochemistry on mouse samples at 1:100 (fig s5). Cell Tissue Res (2014) ncbi |
rabbit polyclonal |
| In order to study the role of ZO proteins in the regulation of transcription factor DbpA/ZONAB, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in western blot on dog samples . J Biol Chem (2014) ncbi |
rabbit polyclonal |
| In order to investigate the expression of the tight junction proteins occludin, claudin-1 and ZO-2 in the epidermis of female mice, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2) and in western blot on mouse samples at 1:1000 (fig 1). Exp Cell Res (2013) ncbi |
rabbit polyclonal |
| In order to study the effect of endotoxemia on the progression of encephalopathy in relation to BBB permeability during acute liver failure, Invitrogen ZO 2 antibody (Invitrogen, 38-9100) was used in western blot on mouse samples at 1:1000. Liver Int (2014) ncbi |
rabbit polyclonal |
| In order to investigate the regulation of ZO-1 by p38delta mitogen-activated protein kinase in differentiating human epidermal keratinocytes, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in western blot on human samples at 1:1000. Arch Dermatol Res (2014) ncbi |
rabbit polyclonal |
| In order to identify the mechanism for the vascular permeability syndrome and respiratory distress in severe dengue, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on dog samples at 1:100. J Virol (2013) ncbi |
rabbit polyclonal |
| In order to use Isl1-Cre to investigate the roles of Foxa2 in the prechordal plate and ventral endoderm, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on mouse samples at 1:200 (fig 7). Biol Open (2012) ncbi |
rabbit polyclonal |
| In order to assess the relationship between zona occludens-2 and the Wnt/beta-catenin pathway in podocyte injury and proteinuria, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunohistochemistry - free floating section on mouse samples at 1:50 (fig 3). Am J Physiol Renal Physiol (2013) ncbi |
rabbit polyclonal |
| In order to determine the expression pattern of selected components involved in the formation of tight junctions in relation to gastroesophageal reflux disease, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on human samples at 1:30 (fig 2). BMC Gastroenterol (2012) ncbi |
rabbit polyclonal |
| In order to investigate the roles of ZO-1 in mouse embryonic stem cells, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunocytochemistry on mouse samples (fig 2). Stem Cells (2012) ncbi |
rabbit polyclonal |
| In order to study the junctional complexes of liver sinusoidal endothelial cells, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunohistochemistry on rat samples (fig 5). PLoS ONE (2012) ncbi |
rabbit polyclonal |
| In order to investigate the effect of ouabain on cilia development in epithelial cells, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on dog samples (fig 2e). Proc Natl Acad Sci U S A (2011) ncbi |
rabbit polyclonal |
| In order to assess the effects of stabilizing the blood brain barrier function by therapeutic targeting tight junction proteins for experimental autoimmune encephalomyelitis, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunohistochemistry - frozen section on mouse samples (tbl 1). Acta Neuropathol (2011) ncbi |
rabbit polyclonal |
| In order to elucidate the role of zonula occludens-2 in trophectoderm differentiation and blastocyst formation in hamsters, Invitrogen ZO 2 antibody (Invitrogen, 71-1400) was used in immunocytochemistry on mouse samples (fig 1). Theriogenology (2011) ncbi |
rabbit polyclonal |
| In order to discuss the mechanisms by which the blood brain barrier and the blood-cerebrospinal fluid barrier are dysregulated during inflammation, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunohistochemistry on mouse samples (fig 4). Antioxid Redox Signal (2011) ncbi |
rabbit polyclonal |
| In order to study the role of CD44 in tight-junction assembly and barrier function, Invitrogen ZO 2 antibody (Zymed, 38-9100) was used in immunohistochemistry on mouse samples (fig s2) and in western blot on mouse samples (fig s2). J Invest Dermatol (2011) ncbi |
rabbit polyclonal |
| In order to identify ZASP as a binding partner of ZO-2, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in immunoprecipitation on dog samples (fig 3), in immunocytochemistry on dog samples at 1:100 (fig 4) and in western blot on dog samples at 1:1000 (fig 3). Exp Cell Res (2010) ncbi |
rabbit polyclonal |
| In order to measure the expression of tight junction proteins in the cerebral cortex, cerebellum, and spinal cord of fetuses after maternal treatment with dexamethasone, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used in western blot on sheep samples at 1:5000. Am J Physiol Heart Circ Physiol (2010) ncbi |
rabbit polyclonal | In order to examine the architecture of cellular junctions present in blood and lymphatic vessel endothelium in peripheral lymph nodes, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . Eur J Immunol (2008) ncbi | |
rabbit polyclonal | In order to study the effects of cingulin overexpression, Invitrogen ZO 2 antibody (Zymed, 71- 1400) was used . Mol Membr Biol (2008) ncbi | |
rabbit polyclonal | In order to investigate the role of zona occludens-2 in the regulation of cyclin D1 transcription, Invitrogen ZO 2 antibody (Zymed Laboratories, 71-1400) was used . Mol Biol Cell (2007) ncbi | |
rabbit polyclonal | In order to ascertain the role of ZO-2 in epithelial cells, Invitrogen ZO 2 antibody (Zymed Laboratories, 71-1400) was used . Exp Cell Res (2007) ncbi | |
rabbit polyclonal | In order to study the co-association of connexin36, zonula occludens-1, zonula occludens-2, and Y-box transcription factor 3 in mouse and rat retina, Invitrogen ZO 2 antibody (Invitrogen/Zymed, 71-1400) was used . Neuroscience (2006) ncbi | |
rabbit polyclonal | In order to test if HDAC inhibitors affect the expression of tight junction proteins, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . Mol Cancer Res (2004) ncbi | |
rabbit polyclonal | In order to test if lack of junctional cingulin affects tight-junction organization and function, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . J Cell Sci (2004) ncbi | |
rabbit polyclonal | In order to characterize the nuclear functions of ZO-2, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . Exp Cell Res (2004) ncbi | |
rabbit polyclonal | In order to characterize the disruption of the barrier integrity in rat ileum after irradiation, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . Can J Physiol Pharmacol (2004) ncbi | |
rabbit polyclonal | In order to examine the role of nuclear ZO-2, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . Exp Cell Res (2004) ncbi | |
rabbit polyclonal | In order to investigate the use of vitamin D analogues to treat colon cancer, Invitrogen ZO 2 antibody (Zymed, 71-1400) was used . J Cell Biol (2001) ncbi |
Cell Signaling Technology
rabbit polyclonal |
| Cell Signaling Technology ZO 2 antibody (Cell Signaling Technology, 2847) was used in western blot on human samples at 1:1000 (fig s8). J Clin Invest (2016) ncbi |
rabbit polyclonal |
| Cell Signaling Technology ZO 2 antibody (Cell Signaling Technology, 2847) was used in immunohistochemistry on mouse samples at 1:100 (fig 5b) and in western blot on mouse samples at 1:1000 (fig 5f). Endocrinology (2015) ncbi |
rabbit polyclonal |
| In order to determine the precise role of actin in the neural epithelium, Cell Signaling Technology ZO 2 antibody (Cell Signaling, 2847) was used in immunohistochemistry on mouse samples at 1:200 (fig 7). Development (2015) ncbi |
Articles Reviewed
- Raya Sandino A, Castillo Kauil A, Domínguez Calderón A, Alarcón L, Flores Benitez D, Cuellar Perez F, et al. Zonula occludens-2 regulates Rho proteins activity and the development of epithelial cytoarchitecture and barrier function. Biochim Biophys Acta Mol Cell Res. 2017;1864:1714-1733 pubmed publisher
- de Andrade G, Kunzelman L, Merrill M, Fuerst P. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina. Mol Vis. 2014;20:1422-33 pubmed
- Puerta Guardo H, Raya Sandino A, Gonzalez Mariscal L, Rosales V, Ayala Davila J, Chávez Mungía B, et al. The cytokine response of U937-derived macrophages infected through antibody-dependent enhancement of dengue virus disrupts cell apical-junction complexes and increases vascular permeability. J Virol. 2013;87:7486-501 pubmed publisher
- Paschoud S, Citi S. Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008;25:1-13 pubmed
- Huerta M, Munoz R, Tapia R, Soto Reyes E, Ramírez L, Recillas Targa F, et al. Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. Mol Biol Cell. 2007;18:4826-36 pubmed
- Hernandez S, Chavez Munguia B, Gonzalez Mariscal L. ZO-2 silencing in epithelial cells perturbs the gate and fence function of tight junctions and leads to an atypical monolayer architecture. Exp Cell Res. 2007;313:1533-47 pubmed
- Ciolofan C, Li X, Olson C, Kamasawa N, Gebhardt B, Yasumura T, et al. Association of connexin36 and zonula occludens-1 with zonula occludens-2 and the transcription factor zonula occludens-1-associated nucleic acid-binding protein at neuronal gap junctions in rodent retina. Neuroscience. 2006;140:433-51 pubmed
- Bordin M, D Atri F, Guillemot L, Citi S. Histone deacetylase inhibitors up-regulate the expression of tight junction proteins. Mol Cancer Res. 2004;2:692-701 pubmed
- Guillemot L, Hammar E, Kaister C, Ritz J, Caille D, Jond L, et al. Disruption of the cingulin gene does not prevent tight junction formation but alters gene expression. J Cell Sci. 2004;117:5245-56 pubmed
- Jaramillo B, Ponce A, Moreno J, Betanzos A, Huerta M, Lopez Bayghen E, et al. Characterization of the tight junction protein ZO-2 localized at the nucleus of epithelial cells. Exp Cell Res. 2004;297:247-58 pubmed
- Dublineau I, Lebrun F, Grison S, Griffiths N. Functional and structural alterations of epithelial barrier properties of rat ileum following X-irradiation. Can J Physiol Pharmacol. 2004;82:84-93 pubmed
- Betanzos A, Huerta M, Lopez Bayghen E, Azuara E, Amerena J, Gonzalez Mariscal L. The tight junction protein ZO-2 associates with Jun, Fos and C/EBP transcription factors in epithelial cells. Exp Cell Res. 2004;292:51-66 pubmed
- Pálmer H, González Sancho J, Espada J, Berciano M, Puig I, Baulida J, et al. Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol. 2001;154:369-87 pubmed
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