This is a Validated Antibody Database (VAD) review about mouse Xrcc5, based on 10 published articles (read how Labome selects the articles), using Xrcc5 antibody in all methods. It is aimed to help Labome visitors find the most suited Xrcc5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Xrcc5 synonym: AI314015; CTC85; CTCBF; Ku80; Ku86

Invitrogen
mouse monoclonal (111)
  • western blot; human; 1:1000; loading ...; fig 4d
Invitrogen Xrcc5 antibody (Thermo Fisher Scientific, MA5-12933) was used in western blot on human samples at 1:1000 (fig 4d). Cell Rep (2018) ncbi
mouse monoclonal (5C5)
  • western blot; mouse; fig s9a
In order to evaluate the effectiveness of a combinatory approach to eradicate leukemia cells, Invitrogen Xrcc5 antibody (Thermo Fisher Scientific, MA5-15873) was used in western blot on mouse samples (fig s9a). J Clin Invest (2017) ncbi
mouse monoclonal (111)
  • western blot; mouse; loading ...; fig 1f
In order to assess the contributions of single-strand annealing factors HR Rad52 and translesion DNA polymerase q to CSR, Invitrogen Xrcc5 antibody (Thermo Fisher Scientific, 111) was used in western blot on mouse samples (fig 1f). Nat Commun (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 3
In order to study how miR-622 promotes resistance to PARP inhibitors and platinum in BRCA1 mutant high-grade serous ovarian carcinomas, Invitrogen Xrcc5 antibody (Thermo Scientific, PA5-17454) was used in western blot on human samples (fig 3). Cell Rep (2016) ncbi
mouse monoclonal (111)
  • immunoprecipitation; human; fig 1a
  • western blot; human
In order to investigate the role of phospho-Ku70 in DNA repair, Invitrogen Xrcc5 antibody (Thermo Scientific, 111) was used in immunoprecipitation on human samples (fig 1a) and in western blot on human samples . Oncotarget (2015) ncbi
mouse monoclonal (111)
  • western blot; human; fig 5
In order to analyze effective tumor control in human lung cancer cells by the combination of heavy-ion irradiation and Hsp90 inhibitor 17AAG, Invitrogen Xrcc5 antibody (Thermo Scientific, 111) was used in western blot on human samples (fig 5). Cancer Med (2015) ncbi
mouse monoclonal (111)
In order to investigate regulation of antigens NY-ESO-1 and MAGE-C1 within cancer cell lines, Invitrogen Xrcc5 antibody (Neomarker, Ab-2) was used . PLoS ONE (2013) ncbi
mouse monoclonal (111)
  • immunocytochemistry; human; 1:100; tbl 2
  • western blot; human; 1:2000; tbl 2
In order to develop a new method to visualize DNA double-strand break complexes, Invitrogen Xrcc5 antibody (Thermo Fisher, 111) was used in immunocytochemistry on human samples at 1:100 (tbl 2) and in western blot on human samples at 1:2000 (tbl 2). J Cell Biol (2013) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s4c
Cell Signaling Technology Xrcc5 antibody (Cell Signaling, 2753) was used in western blot on mouse samples (fig s4c). iScience (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig s1a
Cell Signaling Technology Xrcc5 antibody (Cell Signaling, 2753) was used in western blot on human samples (fig s1a). Cell Death Dis (2016) ncbi
Articles Reviewed
  1. Chu S, Chabon J, Matovina C, Minehart J, Chen B, Zhang J, et al. Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development. iScience. 2020;23:100941 pubmed publisher
  2. Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  3. Nieborowska Skorska M, Sullivan K, Dasgupta Y, Podszywalow Bartnicka P, Hoser G, Maifrede S, et al. Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells. J Clin Invest. 2017;127:2392-2406 pubmed publisher
  4. Zan H, Tat C, Qiu Z, Taylor J, Guerrero J, Shen T, et al. Rad52 competes with Ku70/Ku86 for binding to S-region DSB ends to modulate antibody class-switch DNA recombination. Nat Commun. 2017;8:14244 pubmed publisher
  5. Narayanaswamy P, Tkachuk S, Haller H, Dumler I, Kiyan Y. CHK1 and RAD51 activation after DNA damage is regulated via urokinase receptor/TLR4 signaling. Cell Death Dis. 2016;7:e2383 pubmed publisher
  6. Choi Y, Meghani K, Brault M, Leclerc L, He Y, Day T, et al. Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. Cell Rep. 2016;14:429-439 pubmed publisher
  7. Bouley J, Saad L, Grall R, Schellenbauer A, Biard D, Paget V, et al. A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines. Oncotarget. 2015;6:27980-8000 pubmed publisher
  8. Hirakawa H, Fujisawa H, Masaoka A, Noguchi M, Hirayama R, Takahashi M, et al. The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells. Cancer Med. 2015;4:426-36 pubmed publisher
  9. Pagotto A, Caballero O, Volkmar N, Devalle S, Simpson A, Lu X, et al. Centrosomal localisation of the cancer/testis (CT) antigens NY-ESO-1 and MAGE-C1 is regulated by proteasome activity in tumour cells. PLoS ONE. 2013;8:e83212 pubmed publisher
  10. Britton S, Coates J, Jackson S. A new method for high-resolution imaging of Ku foci to decipher mechanisms of DNA double-strand break repair. J Cell Biol. 2013;202:579-95 pubmed publisher