This is a Validated Antibody Database (VAD) review about mouse Wnt5a, based on 17 published articles (read how Labome selects the articles), using Wnt5a antibody in all methods. It is aimed to help Labome visitors find the most suited Wnt5a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Wnt5a synonym: 8030457G12Rik; Wnt-5a

Knockout validation
R&D Systems
rat monoclonal (442625)
  • western blot knockout validation; human; 1:300; loading ...; fig 1c
R&D Systems Wnt5a antibody (R&D Systems, MAB645) was used in western blot knockout validation on human samples at 1:300 (fig 1c). Oncogene (2018) ncbi
Santa Cruz Biotechnology
mouse monoclonal (A-5)
  • western blot; mouse; loading ...; fig s3b
  • western blot; human; fig 7b
Santa Cruz Biotechnology Wnt5a antibody (Santa Cruz, sc-365370) was used in western blot on mouse samples (fig s3b) and in western blot on human samples (fig 7b). J Clin Invest (2020) ncbi
mouse monoclonal (A-5)
  • immunohistochemistry - frozen section; human; 1:50; loading ...; fig 4c
Santa Cruz Biotechnology Wnt5a antibody (Santa Cruz, sc-365370) was used in immunohistochemistry - frozen section on human samples at 1:50 (fig 4c). Nat Neurosci (2019) ncbi
mouse monoclonal (A-5)
  • western blot; human; fig s1
Santa Cruz Biotechnology Wnt5a antibody (Santa Cruz, sc-365370) was used in western blot on human samples (fig s1). Int J Mol Sci (2016) ncbi
mouse monoclonal (A-5)
  • western blot; human; fig 2
Santa Cruz Biotechnology Wnt5a antibody (santa Cruz, sc-365370) was used in western blot on human samples (fig 2). BMC Res Notes (2015) ncbi
mouse monoclonal (A-5)
  • western blot; mouse; fig 4a
Santa Cruz Biotechnology Wnt5a antibody (Santa Cruz Biotechnology, sc-365370) was used in western blot on mouse samples (fig 4a). PLoS ONE (2015) ncbi
mouse monoclonal (A-5)
  • western blot; mouse
Santa Cruz Biotechnology Wnt5a antibody (Santa Cruz, sc-365370) was used in western blot on mouse samples . Exp Cell Res (2014) ncbi
R&D Systems
domestic goat polyclonal
  • western blot; human; loading ...; fig 7a
R&D Systems Wnt5a antibody (R&D Systems, AF645) was used in western blot on human samples (fig 7a). EMBO J (2018) ncbi
rat monoclonal (442625)
  • western blot knockout validation; human; 1:300; loading ...; fig 1c
R&D Systems Wnt5a antibody (R&D Systems, MAB645) was used in western blot knockout validation on human samples at 1:300 (fig 1c). Oncogene (2018) ncbi
rat monoclonal (442625)
  • western blot; mouse; loading ...; fig 1a
  • western blot; human; loading ...; fig 2d, 3f
R&D Systems Wnt5a antibody (R&D, MAB645) was used in western blot on mouse samples (fig 1a) and in western blot on human samples (fig 2d, 3f). J Exp Med (2017) ncbi
domestic goat polyclonal
  • western blot; human; 1:300; loading ...; fig s3d
In order to research the Wnt5a/DVL1 signaling pathway and its role on ribosomal DNA transcription, R&D Systems Wnt5a antibody (R&D, AF645) was used in western blot on human samples at 1:300 (fig s3d). PLoS Genet (2016) ncbi
domestic goat polyclonal
  • immunohistochemistry - frozen section; mouse; 1:20; loading ...; fig s2e
In order to study factors that influence the expansion and movement of primordial germ cells, R&D Systems Wnt5a antibody (R&D Systems, AF645) was used in immunohistochemistry - frozen section on mouse samples at 1:20 (fig s2e). J Cell Biol (2016) ncbi
domestic goat polyclonal
  • immunocytochemistry; human; 1:500; fig 3
R&D Systems Wnt5a antibody (R&D Systems, AF645) was used in immunocytochemistry on human samples at 1:500 (fig 3). PLoS ONE (2016) ncbi
rat monoclonal (442625)
  • immunohistochemistry - frozen section; mouse; fig 1
R&D Systems Wnt5a antibody (R&D Systems, MAB645) was used in immunohistochemistry - frozen section on mouse samples (fig 1). Dev Biol (2016) ncbi
rat monoclonal (442625)
  • western blot; human; fig 1
R&D Systems Wnt5a antibody (R&D, MAB645) was used in western blot on human samples (fig 1). Clin Exp Metastasis (2016) ncbi
rat monoclonal (442625)
  • western blot; mouse; 1:250; fig 3
In order to assess MTV-Wnt1 tumors and how Wnt5a suppresses tumor formation and redirects tumor phenotype, R&D Systems Wnt5a antibody (R&D Systems, MAB645) was used in western blot on mouse samples at 1:250 (fig 3). PLoS ONE (2014) ncbi
rat monoclonal (442625)
  • western blot; human; 1:5000; fig 2a
R&D Systems Wnt5a antibody (R&D, Mab-645) was used in western blot on human samples at 1:5000 (fig 2a). Dev Biol (2013) ncbi
Cell Signaling Technology
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4c
Cell Signaling Technology Wnt5a antibody (Cell Signaling, 2392S) was used in western blot on mouse samples (fig 4c). EBioMedicine (2019) ncbi
Articles Reviewed
  1. Theivanthiran B, Evans K, Devito N, Plebanek M, Sturdivant M, Wachsmuth L, et al. A tumor-intrinsic PD-L1/NLRP3 inflammasome signaling pathway drives resistance to anti-PD-1 immunotherapy. J Clin Invest. 2020;130:2570-2586 pubmed publisher
  2. Giandomenico S, Mierau S, Gibbons G, Wenger L, Masullo L, Sit T, et al. Cerebral organoids at the air-liquid interface generate diverse nerve tracts with functional output. Nat Neurosci. 2019;22:669-679 pubmed publisher
  3. Li J, Wang Y, Ma M, Jiang S, Zhang X, Zhang Y, et al. Autocrine CTHRC1 activates hepatic stellate cells and promotes liver fibrosis by activating TGF-β signaling. EBioMedicine. 2019;40:43-55 pubmed publisher
  4. Glaeser K, Urban M, Fenech E, Voloshanenko O, Kranz D, Lari F, et al. ERAD-dependent control of the Wnt secretory factor Evi. EMBO J. 2018;37: pubmed publisher
  5. Han B, Zhou B, Qu Y, Gao B, Xu Y, Chung S, et al. FOXC1-induced non-canonical WNT5A-MMP7 signaling regulates invasiveness in triple-negative breast cancer. Oncogene. 2018;37:1399-1408 pubmed publisher
  6. Baarsma H, Skronska Wasek W, Mutze K, Ciolek F, Wagner D, John Schuster G, et al. Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD. J Exp Med. 2017;214:143-163 pubmed publisher
  7. Dass R, Sarshad A, Carson B, Feenstra J, Kaur A, Obrdlik A, et al. Wnt5a Signals through DVL1 to Repress Ribosomal DNA Transcription by RNA Polymerase I. PLoS Genet. 2016;12:e1006217 pubmed publisher
  8. Cantú A, Altshuler Keylin S, Laird D. Discrete somatic niches coordinate proliferation and migration of primordial germ cells via Wnt signaling. J Cell Biol. 2016;214:215-29 pubmed publisher
  9. Skaria T, Burgener J, Bächli E, Schoedon G. IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling. PLoS ONE. 2016;11:e0156002 pubmed publisher
  10. Li D, Sinha T, Ajima R, Seo H, Yamaguchi T, Wang J. Spatial regulation of cell cohesion by Wnt5a during second heart field progenitor deployment. Dev Biol. 2016;412:18-31 pubmed publisher
  11. Bleckmann A, Conradi L, Menck K, Schmick N, Schubert A, Rietkötter E, et al. β-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastases. Clin Exp Metastasis. 2016;33:309-23 pubmed publisher
  12. Ozeki N, Mogi M, Hase N, Hiyama T, Yamaguchi H, Kawai R, et al. Wnt16 Signaling Is Required for IL-1β-Induced Matrix Metalloproteinase-13-Regulated Proliferation of Human Stem Cell-Derived Osteoblastic Cells. Int J Mol Sci. 2016;17:221 pubmed publisher
  13. Herzog J, Rid R, Wagner M, Hundsberger H, Eger A, Bauer J, et al. Whole-transcriptome gene expression profiling in an epidermolysis bullosa simplex Dowling-Meara model keratinocyte cell line uncovered novel, potential therapeutic targets and affected pathways. BMC Res Notes. 2015;8:785 pubmed publisher
  14. Ozeki N, Hase N, Hiyama T, Yamaguchi H, Kawai R, Kondo A, et al. Interleukin-1β-induced autophagy-related gene 5 regulates proliferation of embryonic stem cell-derived odontoblastic cells. PLoS ONE. 2015;10:e0124542 pubmed publisher
  15. Easter S, Mitchell E, Baxley S, Desmond R, Frost A, Serra R. Wnt5a suppresses tumor formation and redirects tumor phenotype in MMTV-Wnt1 tumors. PLoS ONE. 2014;9:e113247 pubmed publisher
  16. Ozeki N, Hase N, Hiyama T, Yamaguchi H, Kawai R, Kondo A, et al. IL-1?-induced, matrix metalloproteinase-3-regulated proliferation of embryonic stem cell-derived odontoblastic cells is mediated by the Wnt5 signaling pathway. Exp Cell Res. 2014;328:69-86 pubmed publisher
  17. Buttler K, Becker J, Pukrop T, Wilting J. Maldevelopment of dermal lymphatics in Wnt5a-knockout-mice. Dev Biol. 2013;381:365-76 pubmed publisher