This is a Validated Antibody Database (VAD) review about mouse Vhl, based on 5 published articles (read how Labome selects the articles), using Vhl antibody in all methods. It is aimed to help Labome visitors find the most suited Vhl antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Vhl synonym: Vhlh; von Hippel-Lindau disease tumor suppressor; pVHL; von Hippel-Lindau syndrome homolog; von Hippel-Lindau syndrome protein homolog

Knockout validation
MyBioSource
rabbit polyclonal
  • western blot knockout validation; human; fig 1
In order to determine the regulation of von Hippel Lindau proteostasis and function by phosphorylation-dependent cleavage, MyBioSource Vhl antibody (MyBioSource, MBS125962) was used in western blot knockout validation on human samples (fig 1). Oncogene (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-7)
  • western blot; human; fig 4
Santa Cruz Biotechnology Vhl antibody (Santa Cruz, D-7) was used in western blot on human samples (fig 4). J Cell Sci (2016) ncbi
mouse monoclonal (G-7)
  • western blot; human
Santa Cruz Biotechnology Vhl antibody (Santa Cruz Biotechnology, SC-17780) was used in western blot on human samples . Br J Pharmacol (2015) ncbi
mouse monoclonal (D-7)
  • immunocytochemistry; human; fig 1
Santa Cruz Biotechnology Vhl antibody (Santa Cruz, sc-55506) was used in immunocytochemistry on human samples (fig 1). Oncotarget (2015) ncbi
MyBioSource
rabbit polyclonal
  • western blot knockout validation; human; fig 1
In order to determine the regulation of von Hippel Lindau proteostasis and function by phosphorylation-dependent cleavage, MyBioSource Vhl antibody (MyBioSource, MBS125962) was used in western blot knockout validation on human samples (fig 1). Oncogene (2016) ncbi
Invitrogen
mouse monoclonal (Ig33)
  • immunohistochemistry - paraffin section; human; 1:200
In order to study the effect of genetic alterations and protein expression of Von Hipple-Lindau and the C1772T SNP of HIF-1alpha gene on prognosis in early-stage clear cell renal cell carcinoma, Invitrogen Vhl antibody (Lab Vision, Ig33) was used in immunohistochemistry - paraffin section on human samples at 1:200. Med Oncol (2014) ncbi
Articles Reviewed
  1. German P, Bai S, Liu X, Sun M, Zhou L, Kalra S, et al. Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function. Oncogene. 2016;35:4973-80 pubmed publisher
  2. Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1α. J Cell Sci. 2016;129:817-30 pubmed publisher
  3. Kim B, Lee J, Choi J, Park D, Song H, Park T, et al. Imidazole-based alkaloid derivative LCB54-0009 suppresses ocular angiogenesis and lymphangiogenesis in models of experimental retinopathy and corneal neovascularization. Br J Pharmacol. 2015;172:3875-89 pubmed publisher
  4. Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, et al. ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer. Oncotarget. 2015;6:6959-76 pubmed
  5. Lessi F, Mazzanti C, Tomei S, Di Cristofano C, Minervini A, Menicagli M, et al. VHL and HIF-1?: gene variations and prognosis in early-stage clear cell renal cell carcinoma. Med Oncol. 2014;31:840 pubmed publisher