This is a Validated Antibody Database (VAD) review about mouse Vamp2, based on 37 published articles (read how Labome selects the articles), using Vamp2 antibody in all methods. It is aimed to help Labome visitors find the most suited Vamp2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Vamp2 synonym: Syb-2; Syb2; Vamp-2; sybII; vesicle-associated membrane protein 2; synaptobrevin II; synaptobrevin-2; vesicle-associated membrane 2

Synaptic Systems
rabbit polyclonal (/)
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104202) was used . Science (2019) ncbi
rabbit polyclonal (/)
  • immunohistochemistry; mouse; fig 1g
  • western blot; mouse; fig s1c
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104202) was used in immunohistochemistry on mouse samples (fig 1g) and in western blot on mouse samples (fig s1c). Cell (2018) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; fig 2e
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 211) was used in western blot on mouse samples (fig 2e). Neural Plast (2017) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; cow; fig 1b
  • western blot; cow; fig s1
Synaptic Systems Vamp2 antibody (Synaptic Systems, 69.1) was used in immunocytochemistry on cow samples (fig 1b) and in western blot on cow samples (fig s1). Sci Rep (2017) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 7e
Synaptic Systems Vamp2 antibody (SySy, 69.1) was used in immunocytochemistry on mouse samples at 1:1000 (fig 7e). J Neurosci (2017) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; loading ...; tbl 1
In order to elucidate the contribution of the Sac phosphatase domain of Synaptojanin 1 to neurological symptoms, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 211) was used in western blot on mouse samples (tbl 1). Neuron (2017) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; rat; loading ...; fig 8b
  • western blot; mouse; loading ...; fig 4
In order to generate an atoxic derivative of Botulism neurotoxin/C1 and assess whether it retains neuron-specific targeting without concomitant toxic host responses, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunocytochemistry on rat samples (fig 8b) and in western blot on mouse samples (fig 4). Sci Rep (2017) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 3a
  • western blot; mouse; 1:5000; loading ...; fig 1a
In order to evaluate the application of CRISPR/Cas9 system in postmitotic cells, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 211) was used in immunohistochemistry on mouse samples at 1:1000 (fig 3a) and in western blot on mouse samples at 1:5000 (fig 1a). J Neurosci Methods (2017) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; rat; 1:4000; loading ...; fig 5c
  • western blot; rat; 1:4000; loading ...; fig 5a
In order to develop methods to study vesicle-associated proteins and exocytosis in stellate astrocytes, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunocytochemistry on rat samples at 1:4000 (fig 5c) and in western blot on rat samples at 1:4000 (fig 5a). J Gen Physiol (2017) ncbi
guinea pigs polyclonal (/)
  • immunocytochemistry; rat; 1:500; loading ...; fig 5c
  • western blot; rat; 1:500; loading ...; fig 5a
In order to develop methods to study vesicle-associated proteins and exocytosis in stellate astrocytes, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104204) was used in immunocytochemistry on rat samples at 1:500 (fig 5c) and in western blot on rat samples at 1:500 (fig 5a). J Gen Physiol (2017) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; mouse; fig 4b
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunocytochemistry on mouse samples (fig 4b). J Cell Biol (2016) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5b
  • western blot; mouse; loading ...; fig 7d
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunohistochemistry - paraffin section on mouse samples (fig 5b) and in western blot on mouse samples (fig 7d). J Cell Biol (2016) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; loading ...; fig 3a
In order to investigate the function of extended synaptotagmins in knock out mice, Synaptic Systems Vamp2 antibody (Synaptic systems, 69.1) was used in western blot on mouse samples (fig 3a). PLoS ONE (2016) ncbi
rabbit polyclonal (/)
  • immunocytochemistry; mouse; 1:200; fig 4
Synaptic Systems Vamp2 antibody (Synaptic System, 104203) was used in immunocytochemistry on mouse samples at 1:200 (fig 4). Acta Neuropathol Commun (2016) ncbi
rabbit polyclonal (/)
  • immunocytochemistry; rat; fig 2
In order to study Arf6 and how it regulates cylcing of releasable synaptic vesicles at the hippocampal synapse, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 202) was used in immunocytochemistry on rat samples (fig 2). elife (2016) ncbi
rabbit polyclonal (/)
  • immunocytochemistry; rat; 1:500; fig S4
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104202) was used in immunocytochemistry on rat samples at 1:500 (fig S4). Sci Rep (2015) ncbi
mouse monoclonal (69.1)
  • western blot; human; 1:10,000; fig 6B
Synaptic Systems Vamp2 antibody (Synaptic System, 104211) was used in western blot on human samples at 1:10,000 (fig 6B). Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (69.1)
  • western blot; rat; fig 1
In order to characterize inhibition of clathrin-mediated and bulk endocytosis by synaptotagmin-11, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in western blot on rat samples (fig 1). EMBO Rep (2016) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; fig 6
  • western blot; human; fig 8
Synaptic Systems Vamp2 antibody (Synaptic Systems, cl. 69.1) was used in western blot on mouse samples (fig 6) and in western blot on human samples (fig 8). PLoS Biol (2015) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry - frozen section; mouse; fig 5
  • western blot; mouse; fig 5
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 211) was used in immunohistochemistry - frozen section on mouse samples (fig 5) and in western blot on mouse samples (fig 5). PLoS ONE (2015) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - paraffin section; mouse; 1:1000; loading ...; fig 5c
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104202) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000 (fig 5c). Nat Commun (2015) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry; mouse; 1:1000; fig 5
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104-C211) was used in immunohistochemistry on mouse samples at 1:1000 (fig 5). J Neurosci (2015) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; 1:200; fig 2
Synaptic Systems Vamp2 antibody (Synaptic systems, 104 211) was used in western blot on mouse samples at 1:200 (fig 2). Nat Neurosci (2015) ncbi
rabbit polyclonal (/)
  • western blot; mouse; 1:2500
In order to determine the effect of the G2019S mutation of LRRK2 has on the synaptic release of mammalian neurons, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104 202) was used in western blot on mouse samples at 1:2500. Front Cell Neurosci (2014) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry - frozen section; mouse; fig 2c
  • western blot; mouse; fig 2
In order to elucidate VAMP8- and VAMP2-mediated zymogen granules exocytosis, Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunohistochemistry - frozen section on mouse samples (fig 2c) and in western blot on mouse samples (fig 2). J Biol Chem (2014) ncbi
mouse monoclonal (69.1)
  • western blot; mouse; fig 6
In order to test if presenilin and nicastrin regulate synaptic function in a gamma-secretase-dependent or -independent manner, Synaptic Systems Vamp2 antibody (SYSY, 69.1) was used in western blot on mouse samples (fig 6). Proc Natl Acad Sci U S A (2014) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - frozen section; rat; 1:250
  • western blot; rat; 1:1000
Synaptic Systems Vamp2 antibody (SYSY, 104 202) was used in immunohistochemistry - frozen section on rat samples at 1:250 and in western blot on rat samples at 1:1000. Neuroscience (2014) ncbi
mouse monoclonal (69.1)
  • immunohistochemistry - frozen section; rat; 1:250
  • western blot; rat; 1:1000
Synaptic Systems Vamp2 antibody (SYSY, 104 211) was used in immunohistochemistry - frozen section on rat samples at 1:250 and in western blot on rat samples at 1:1000. Neuroscience (2014) ncbi
mouse monoclonal (69.1)
  • immunocytochemistry; rat
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104211) was used in immunocytochemistry on rat samples . PLoS ONE (2014) ncbi
rabbit polyclonal (/)
  • immunohistochemistry - frozen section; mouse; 1:5000
Synaptic Systems Vamp2 antibody (Synaptic Systems, 104-202) was used in immunohistochemistry - frozen section on mouse samples at 1:5000. J Comp Neurol (2010) ncbi
R&D Systems
mouse monoclonal (541405)
  • western blot; human; 1:2000; loading ...; fig 5c
R&D Systems Vamp2 antibody (R&D Systems, MAB5136) was used in western blot on human samples at 1:2000 (fig 5c). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (541405)
  • western blot; human; fig 10c
R&D Systems Vamp2 antibody (R&D Systems, MAB5136-SP) was used in western blot on human samples (fig 10c). J Biol Chem (2017) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-11)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 2e
Santa Cruz Biotechnology Vamp2 antibody (SantaCruz, sc-133129) was used in immunocytochemistry on mouse samples at 1:100 (fig 2e). J Immunol Methods (2017) ncbi
mouse monoclonal (4E240)
  • western blot; mouse; fig 1
Santa Cruz Biotechnology Vamp2 antibody (Santa Cruz, sc58309) was used in western blot on mouse samples (fig 1). Diabetes (2013) ncbi
Abcam
rabbit monoclonal (EPR12790)
  • western blot; mouse; fig 8
Abcam Vamp2 antibody (Abcam, ab181869) was used in western blot on mouse samples (fig 8). Cell Death Dis (2017) ncbi
Invitrogen
rabbit polyclonal
  • immunoprecipitation; human; loading ...; fig 4c
Invitrogen Vamp2 antibody (Affinity Bioreagents, PA1 766) was used in immunoprecipitation on human samples (fig 4c). J Biol Chem (2017) ncbi
rabbit polyclonal
  • western blot; rat; 1:3000; fig 2
In order to study creatine kinase microcompartments and energy metabolism that recruits B-type creatine kinase to specific subcellular sites, Invitrogen Vamp2 antibody (Pierce, PA1-766) was used in western blot on rat samples at 1:3000 (fig 2). Amino Acids (2016) ncbi
rabbit polyclonal
  • western blot; mouse; fig 4
  • western blot; human; fig 4
In order to identify alterations in the islet proteome that characterize the adaptive response, Invitrogen Vamp2 antibody (Thermo Fisher, PA1-766) was used in western blot on mouse samples (fig 4) and in western blot on human samples (fig 4). J Proteome Res (2015) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; common platanna; loading ...; fig s3a
Proteintech Group Vamp2 antibody (Proteintech, 10135-1-AP) was used in immunocytochemistry on common platanna samples (fig s3a). Neuron (2018) ncbi
Sigma-Aldrich
chicken polyclonal
  • immunohistochemistry - frozen section; mouse; fig 2c
In order to elucidate VAMP8- and VAMP2-mediated zymogen granules exocytosis, Sigma-Aldrich Vamp2 antibody (Sigma, gw21451) was used in immunohistochemistry - frozen section on mouse samples (fig 2c). J Biol Chem (2014) ncbi
Articles Reviewed
  1. Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
  2. Cagnetta R, Frese C, Shigeoka T, Krijgsveld J, Holt C. Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. Neuron. 2018;99:29-46.e4 pubmed publisher
  3. Wang Y, Figueiredo D, Sun X, Dong Z, Chen W, Cui W, et al. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc Natl Acad Sci U S A. 2018;115:2508-2513 pubmed publisher
  4. Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser P. Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites. Cell. 2018;172:706-718.e15 pubmed publisher
  5. Yadirgi G, Stickings P, Rajagopal S, Liu Y, Sesardic D. Immuno-detection of cleaved SNAP-25 from differentiated mouse embryonic stem cells provides a sensitive assay for determination of botulinum A toxin and antitoxin potency. J Immunol Methods. 2017;451:90-99 pubmed publisher
  6. Brasher M, Martynowicz D, Grafinger O, Hucik A, Shanks Skinner E, Uniacke J, et al. Interaction of Munc18c and syntaxin4 facilitates invadopodium formation and extracellular matrix invasion of tumor cells. J Biol Chem. 2017;292:16199-16210 pubmed publisher
  7. Biggi S, Buccarello L, Sclip A, Lippiello P, Tonna N, Rumio C, et al. Evidence of Presynaptic Localization and Function of the c-Jun N-Terminal Kinase. Neural Plast. 2017;2017:6468356 pubmed publisher
  8. Gümürdü A, Yildiz R, Eren E, Karakülah G, Unver T, Genc S, et al. MicroRNA exocytosis by large dense-core vesicle fusion. Sci Rep. 2017;7:45661 pubmed publisher
  9. Santos T, Wierda K, Broeke J, Toonen R, Verhage M. Early Golgi Abnormalities and Neurodegeneration upon Loss of Presynaptic Proteins Munc18-1, Syntaxin-1, or SNAP-25. J Neurosci. 2017;37:4525-4539 pubmed publisher
  10. Cao M, Wu Y, Ashrafi G, McCartney A, Wheeler H, Bushong E, et al. Parkinson Sac Domain Mutation in Synaptojanin 1 Impairs Clathrin Uncoating at Synapses and Triggers Dystrophic Changes in Dopaminergic Axons. Neuron. 2017;93:882-896.e5 pubmed publisher
  11. Vazquez Cintron E, Beske P, Tenezaca L, Tran B, Oyler J, Glotfelty E, et al. Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery. Sci Rep. 2017;7:42923 pubmed publisher
  12. Vashi N, Andrabi S, Ghanwat S, Suar M, Kumar D. Ca2+-dependent Focal Exocytosis of Golgi-derived Vesicles Helps Phagocytic Uptake in Macrophages. J Biol Chem. 2017;292:5144-5165 pubmed publisher
  13. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  14. Horvath P, Kavalali E, Monteggia L. CRISPR/Cas9 system-mediated impairment of synaptobrevin/VAMP function in postmitotic hippocampal neurons. J Neurosci Methods. 2017;278:57-64 pubmed publisher
  15. Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher
  16. Shang S, Zhu F, Liu B, Chai Z, Wu Q, Hu M, et al. Intracellular TRPA1 mediates Ca2+ release from lysosomes in dorsal root ganglion neurons. J Cell Biol. 2016;215:369-381 pubmed
  17. Kunii M, Ohara Imaizumi M, Takahashi N, Kobayashi M, Kawakami R, Kondoh Y, et al. Opposing roles for SNAP23 in secretion in exocrine and endocrine pancreatic cells. J Cell Biol. 2016;215:121-138 pubmed
  18. Sclip A, Bacaj T, Giam L, Sudhof T. Extended Synaptotagmin (ESyt) Triple Knock-Out Mice Are Viable and Fertile without Obvious Endoplasmic Reticulum Dysfunction. PLoS ONE. 2016;11:e0158295 pubmed publisher
  19. Schlattner U, Klaus A, Ramírez Ríos S, Guzun R, Kay L, Tokarska Schlattner M. Cellular compartmentation of energy metabolism: creatine kinase microcompartments and recruitment of B-type creatine kinase to specific subcellular sites. Amino Acids. 2016;48:1751-74 pubmed publisher
  20. Schedin Weiss S, Caesar I, Winblad B, Blom H, Tjernberg L. Super-resolution microscopy reveals ?-secretase at both sides of the neuronal synapse. Acta Neuropathol Commun. 2016;4:29 pubmed publisher
  21. Tagliatti E, Fadda M, Falace A, Benfenati F, Fassio A. Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse. elife. 2016;5: pubmed publisher
  22. Craig T, Anderson D, Evans A, Girach F, Henley J. SUMOylation of Syntaxin1A regulates presynaptic endocytosis. Sci Rep. 2015;5:17669 pubmed publisher
  23. Benítez B, Cairns N, Schmidt R, Morris J, Norton J, Cruchaga C, et al. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathol Commun. 2015;3:73 pubmed publisher
  24. Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed publisher
  25. Bacaj T, Wu D, Burré J, Malenka R, Liu X, Sudhof T. Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. PLoS Biol. 2015;13:e1002267 pubmed publisher
  26. Zulliger R, Conley S, Mwoyosvi M, Stuck M, Azadi S, Naash M. SNAREs Interact with Retinal Degeneration Slow and Rod Outer Segment Membrane Protein-1 during Conventional and Unconventional Outer Segment Targeting. PLoS ONE. 2015;10:e0138508 pubmed publisher
  27. Tang L, Craig T, Henley J. SUMOylation of synapsin Ia maintains synaptic vesicle availability and is reduced in an autism mutation. Nat Commun. 2015;6:7728 pubmed publisher
  28. El Ouaamari A, Zhou J, Liew C, Shirakawa J, Dirice E, Gedeon N, et al. Compensatory Islet Response to Insulin Resistance Revealed by Quantitative Proteomics. J Proteome Res. 2015;14:3111-3122 pubmed publisher
  29. Williams M, DeSpenza T, Li M, Gulledge A, Luikart B. Hyperactivity of newborn Pten knock-out neurons results from increased excitatory synaptic drive. J Neurosci. 2015;35:943-59 pubmed publisher
  30. Blanchard J, Eade K, Szucs A, Lo Sardo V, Tsunemoto R, Williams D, et al. Selective conversion of fibroblasts into peripheral sensory neurons. Nat Neurosci. 2015;18:25-35 pubmed publisher
  31. Beccano Kelly D, Kuhlmann N, Tatarnikov I, Volta M, Munsie L, Chou P, et al. Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice. Front Cell Neurosci. 2014;8:301 pubmed publisher
  32. Messenger S, Falkowski M, Thomas D, Jones E, Hong W, Gaisano H, et al. Vesicle associated membrane protein 8 (VAMP8)-mediated zymogen granule exocytosis is dependent on endosomal trafficking via the constitutive-like secretory pathway. J Biol Chem. 2014;289:28040-53 pubmed publisher
  33. Lee S, Sharma M, S dhof T, Shen J. Synaptic function of nicastrin in hippocampal neurons. Proc Natl Acad Sci U S A. 2014;111:8973-8 pubmed publisher
  34. Manca P, Mameli O, Caria M, Torrej n Escribano B, Blasi J. Distribution of SNAP25, VAMP1 and VAMP2 in mature and developing deep cerebellar nuclei after estrogen administration. Neuroscience. 2014;266:102-15 pubmed publisher
  35. Vazquez Cintron E, Vakulenko M, Band P, Stanker L, Johnson E, Ichtchenko K. Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm. PLoS ONE. 2014;9:e85517 pubmed publisher
  36. Song W, Mondal P, Li Y, Lee S, Hussain M. Pancreatic ?-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A. Diabetes. 2013;62:2796-807 pubmed publisher
  37. Phillips M, Otteson D, Sherry D. Progression of neuronal and synaptic remodeling in the rd10 mouse model of retinitis pigmentosa. J Comp Neurol. 2010;518:2071-89 pubmed publisher