This is a Validated Antibody Database (VAD) review about mouse Uchl5, based on 6 published articles (read how Labome selects the articles), using Uchl5 antibody in all methods. It is aimed to help Labome visitors find the most suited Uchl5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Uchl5 synonym: 5830413B11Rik; Uch37; ubiquitin carboxyl-terminal hydrolase isozyme L5; UCH-L5; ubiquitin C-terminal hydrolase 37; ubiquitin C-terminal hydrolase UCH37; ubiquitin thioesterase L5

Abcam
rabbit monoclonal (EP4897)
  • western blot; mouse; 1:2000; loading ...; fig 5a
In order to elucidate the role of HAP40 in Huntington's disease, Abcam Uchl5 antibody (Abcam, ab133508) was used in western blot on mouse samples at 1:2000 (fig 5a). Mol Neurobiol (2017) ncbi
rabbit monoclonal (EP4897)
  • immunohistochemistry - paraffin section; rat; fig 3
  • western blot; rat; fig 3
In order to characterize amelioration of neuronal cell death in a rat model of spontaneous obesity that is dietary-restricted through modulation of ubiquitin proteasome system, Abcam Uchl5 antibody (Abcam, ab133508) was used in immunohistochemistry - paraffin section on rat samples (fig 3) and in western blot on rat samples (fig 3). J Nutr Biochem (2016) ncbi
rabbit monoclonal (EPR4896)
  • western blot; human; fig 4a
In order to elucidate the roles of hRpn13 and Uch37 in cell cycle progression, Abcam Uchl5 antibody (Abcam, ab124931) was used in western blot on human samples (fig 4a). J Biol Chem (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 3
Abcam Uchl5 antibody (Abcam, ab38528) was used in western blot on human samples (fig 3). J Biol Chem (2015) ncbi
Bethyl
rabbit polyclonal
  • RNA immunoprecipitation; human
  • immunocytochemistry; human; 2 ug/ml
  • western blot; human; 0.2 ug/ml
In order to develop reagents to study RNA binding proteins, Bethyl Uchl5 antibody (Bethyl, A304-099A) was used in RNA immunoprecipitation on human samples , in immunocytochemistry on human samples at 2 ug/ml and in western blot on human samples at 0.2 ug/ml. Mol Cell (2016) ncbi
rabbit polyclonal
  • western blot; human; fig 5
Bethyl Uchl5 antibody (Bethyl laboratories, A304-099A) was used in western blot on human samples (fig 5). Chem Biol Drug Des (2015) ncbi
Articles Reviewed
  1. Huang Z, Her L. The Ubiquitin Receptor ADRM1 Modulates HAP40-Induced Proteasome Activity. Mol Neurobiol. 2017;54:7382-7400 pubmed publisher
  2. Shruthi K, Reddy S, Reddy P, Shivalingam P, Harishankar N, Reddy G. Amelioration of neuronal cell death in a spontaneous obese rat model by dietary restriction through modulation of ubiquitin proteasome system. J Nutr Biochem. 2016;33:73-81 pubmed publisher
  3. Sundararaman B, Zhan L, Blue S, Stanton R, Elkins K, Olson S, et al. Resources for the Comprehensive Discovery of Functional RNA Elements. Mol Cell. 2016;61:903-13 pubmed publisher
  4. Randles L, Anchoori R, Roden R, Walters K. The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression. J Biol Chem. 2016;291:8773-83 pubmed publisher
  5. Mahanic C, Budhavarapu V, Graves J, Li G, Lin W. Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37. J Biol Chem. 2015;290:26508-22 pubmed publisher
  6. Wang X, D Arcy P, Caulfield T, Paulus A, Chitta K, Mohanty C, et al. Synthesis and evaluation of derivatives of the proteasome deubiquitinase inhibitor b-AP15. Chem Biol Drug Des. 2015;86:1036-48 pubmed publisher