This is a Validated Antibody Database (VAD) review about mouse Ubc, based on 29 published articles (read how Labome selects the articles), using Ubc antibody in all methods. It is aimed to help Labome visitors find the most suited Ubc antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ubc synonym: 2700054O04Rik; AI194771; Rps27a; TI-225; Uba52; Ubb; polyubiquitin-C; polyubiquitin C

Enzo Life Sciences
mouse monoclonal (HWA4C4)
  • western blot; mouse; loading ...; fig 7f
Enzo Life Sciences Ubc antibody (Enzo, BML-PW0600) was used in western blot on mouse samples (fig 7f). Cell Death Dis (2018) ncbi
mouse monoclonal (HWA4C4)
  • western blot; mouse; 1:500; loading ...; fig 1a
Enzo Life Sciences Ubc antibody (Enzo, HWA4C4) was used in western blot on mouse samples at 1:500 (fig 1a). Mol Metab (2017) ncbi
mouse monoclonal (HWA4C4)
  • western blot; mouse; fig 5
Enzo Life Sciences Ubc antibody (Enzo, HWA4C4) was used in western blot on mouse samples (fig 5). Sci Rep (2015) ncbi
mouse monoclonal (HWA4C4)
  • western blot; scFv; fig 3
Enzo Life Sciences Ubc antibody (Enzo, HWA4C4) was used in western blot on scFv samples (fig 3). J Biol Chem (2015) ncbi
mouse monoclonal (HWA4C4)
  • western blot; mouse; 1:750; fig 1c
In order to elucidate the mechanism by which STAT3 controls NF-kapaB signaling in innate immune cells, Enzo Life Sciences Ubc antibody (Enzo, HWA4C4) was used in western blot on mouse samples at 1:750 (fig 1c). Nat Commun (2014) ncbi
mouse monoclonal (HWA4C4)
  • immunocytochemistry; human
Enzo Life Sciences Ubc antibody (Enzo Life Sciences, BML-PW0600-0025) was used in immunocytochemistry on human samples . PLoS ONE (2012) ncbi
mouse monoclonal (HWA4C4)
  • immunohistochemistry - paraffin section; human; 1:50
Enzo Life Sciences Ubc antibody (Enzo Life Sciences Ltd., HWA4C4) was used in immunohistochemistry - paraffin section on human samples at 1:50. Neurosci Lett (2009) ncbi
BioLegend
mouse monoclonal (P4G7)
  • western blot; human; 1:500; loading ...; fig 6a
In order to elucidate the mechanisms by which ARHGAP36 blocks protein kinase A signaling, BioLegend Ubc antibody (Covance, P4G7) was used in western blot on human samples at 1:500 (fig 6a). Nat Commun (2016) ncbi
mouse monoclonal (P4G7)
  • western blot; human; loading ...; fig 2d
BioLegend Ubc antibody (Covance, P4G7) was used in western blot on human samples (fig 2d). Mol Neurobiol (2016) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; mouse; 1:100; loading ...; fig 1b
Sigma-Aldrich Ubc antibody (Sigma-Aldrich, U5379) was used in western blot on mouse samples at 1:100 (fig 1b). Sci Rep (2018) ncbi
rabbit polyclonal
  • western blot; mouse; fig 5b
In order to investigate the role of inositol-requiring enzyme-1 alpha in glomerular capillary integrity and autophagy in podocytes, Sigma-Aldrich Ubc antibody (Sigma-Aldrich, U5379) was used in western blot on mouse samples (fig 5b). Mol Biol Cell (2017) ncbi
mouse monoclonal (6C1)
  • immunocytochemistry; mouse; loading ...; fig 1g
In order to suggest that ApoL9 is a phosphatidylethanolamine-binding protein, Sigma-Aldrich Ubc antibody (Sigma, U0508) was used in immunocytochemistry on mouse samples (fig 1g). Biochem Biophys Res Commun (2016) ncbi
rabbit polyclonal
  • immunoprecipitation; scFv; fig 3
  • western blot; scFv; fig 3
Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in immunoprecipitation on scFv samples (fig 3) and in western blot on scFv samples (fig 3). PLoS Genet (2016) ncbi
mouse monoclonal (6C1)
  • western blot; human; fig 6
In order to investigate the deficiency that affects SERCA expression and function in the skeletal muscle by Calpain 3, Sigma-Aldrich Ubc antibody (Sigma, U0508) was used in western blot on human samples (fig 6). Expert Rev Mol Med (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
In order to determine how mitochondrial homeostasis is affected by ubiquitin-mediated regulation of E3 ligase GP78 by MGRN1 in trans, Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on human samples at 1:1000 (fig 3). J Cell Sci (2016) ncbi
rabbit polyclonal
  • western blot; human; 1:200; fig 1
In order to examine the role of deubiquitylating enzymes in cholesterol metabolism, Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on human samples at 1:200 (fig 1). J Biol Chem (2016) ncbi
mouse monoclonal (6C1)
  • western blot; tomato; fig 3
In order to study the role of plant drought tolerance by activation of ATG genes and inducing autophagy by Tomato HsfA1a, Sigma-Aldrich Ubc antibody (Sigma-Aldrich, U0508) was used in western blot on tomato samples (fig 3). Autophagy (2015) ncbi
mouse monoclonal (6C1)
  • western blot; human; fig s2
In order to study the fusion between lysosomes and amphisomes/MVBs regulated by mahogunin via ubiquitination of TSG101, Sigma-Aldrich Ubc antibody (Sigma-Aldrich, U0508) was used in western blot on human samples (fig s2). Cell Death Dis (2015) ncbi
rabbit polyclonal
  • western blot; human; fig 2
Sigma-Aldrich Ubc antibody (Sigma, U5319) was used in western blot on human samples (fig 2). PLoS ONE (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:100; fig 6b
In order to investigate how ataxia-telangiectasia mutated signaling regulates pexophagy, Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in immunocytochemistry on human samples at 1:100 (fig 6b). Nat Cell Biol (2015) ncbi
rabbit polyclonal
  • western blot; rat; 1:2000; fig 2
  • western blot; mouse; 1:1000; fig 1
Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on rat samples at 1:2000 (fig 2) and in western blot on mouse samples at 1:1000 (fig 1). PLoS ONE (2015) ncbi
mouse monoclonal (6C1)
  • immunocytochemistry; human; 1:500
Sigma-Aldrich Ubc antibody (Sigma, 6C1) was used in immunocytochemistry on human samples at 1:500. Nucleic Acids Res (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig s5
Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s5). Hum Mol Genet (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:500
Sigma-Aldrich Ubc antibody (SIGMA, U5379) was used in immunohistochemistry - paraffin section on human samples at 1:500. Am J Neurodegener Dis (2014) ncbi
rabbit polyclonal
  • western blot; mouse
In order to examine the accumulation of polyubiquitin conjugates in PiZ mouse liver, Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on mouse samples . PLoS ONE (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:100
Sigma-Aldrich Ubc antibody (Sigma Chemical, U5379) was used in immunocytochemistry on rat samples at 1:100. Toxicol Appl Pharmacol (2014) ncbi
rabbit polyclonal
  • western blot; human; 1:2000
In order to study virus-specific human memory T-cell activation in response to Dribble-mediated cross-presentation of viral antigens, Sigma-Aldrich Ubc antibody (Sigma, 5379) was used in western blot on human samples at 1:2000. J Transl Med (2014) ncbi
rabbit polyclonal
  • western blot; mouse; 1:200; loading ...; fig 1b
Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on mouse samples at 1:200 (fig 1b). J Biol Chem (2014) ncbi
rabbit polyclonal
  • western blot; human
Sigma-Aldrich Ubc antibody (Sigma, U5379) was used in western blot on human samples . FEBS J (2014) ncbi
Articles Reviewed
  1. Su X, Wu C, Ye X, Zeng M, Zhang Z, Che Y, et al. Embryonic lethality in mice lacking Trim59 due to impaired gastrulation development. Cell Death Dis. 2018;9:302 pubmed publisher
  2. Juenemann K, Jansen A, van Riel L, Merkx R, Mulder M, An H, et al. Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies. Sci Rep. 2018;8:1405 pubmed publisher
  3. Kaufman D, Papillon J, Larose L, Iwawaki T, Cybulsky A. Deletion of inositol-requiring enzyme-1? in podocytes disrupts glomerular capillary integrity and autophagy. Mol Biol Cell. 2017;28:1636-1651 pubmed publisher
  4. Cederquist C, Lentucci C, Martinez Calejman C, Hayashi V, Orofino J, GUERTIN D, et al. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017;6:125-137 pubmed publisher
  5. Eccles R, Czajkowski M, Barth C, Müller P, McShane E, Grunwald S, et al. Bimodal antagonism of PKA signalling by ARHGAP36. Nat Commun. 2016;7:12963 pubmed publisher
  6. Arvind T, Rangarajan P. Mouse Apolipoprotein L9 is a phosphatidylethanolamine-binding protein. Biochem Biophys Res Commun. 2016;479:636-642 pubmed publisher
  7. Lin X, Niu D, Hu Z, Kim D, Jin Y, Cai B, et al. An Arabidopsis SUMO E3 Ligase, SIZ1, Negatively Regulates Photomorphogenesis by Promoting COP1 Activity. PLoS Genet. 2016;12:e1006016 pubmed publisher
  8. Toral Ojeda I, Aldanondo G, Lasa Elgarresta J, Lasa Fernández H, Fernandez Torron R, Lopez de Munain A, et al. Calpain 3 deficiency affects SERCA expression and function in the skeletal muscle. Expert Rev Mol Med. 2016;18:e7 pubmed publisher
  9. Mukherjee R, Chakrabarti O. Ubiquitin-mediated regulation of the E3 ligase GP78 by MGRN1 in trans affects mitochondrial homeostasis. J Cell Sci. 2016;129:757-73 pubmed publisher
  10. Nelson J, Cook E, Loregger A, Hoeksema M, Scheij S, Kovacevic I, et al. Deubiquitylase Inhibition Reveals Liver X Receptor-independent Transcriptional Regulation of the E3 Ubiquitin Ligase IDOL and Lipoprotein Uptake. J Biol Chem. 2016;291:4813-25 pubmed publisher
  11. Su X, Yan H, Huang Y, Yun H, Zeng B, Wang E, et al. Expression of FABP4, adipsin and adiponectin in Paneth cells is modulated by gut Lactobacillus. Sci Rep. 2015;5:18588 pubmed publisher
  12. Wang Y, Cai S, Yin L, Shi K, Xia X, Zhou Y, et al. Tomato HsfA1a plays a critical role in plant drought tolerance by activating ATG genes and inducing autophagy. Autophagy. 2015;11:2033-2047 pubmed publisher
  13. Yung C, Sha D, Li L, Chin L. Parkin Protects Against Misfolded SOD1 Toxicity by Promoting Its Aggresome Formation and Autophagic Clearance. Mol Neurobiol. 2016;53:6270-6287 pubmed publisher
  14. Majumder P, Chakrabarti O. Mahogunin regulates fusion between amphisomes/MVBs and lysosomes via ubiquitination of TSG101. Cell Death Dis. 2015;6:e1970 pubmed publisher
  15. Tong X, Zhang D, Guha A, Arthurs B, Cazares V, Gupta N, et al. CUL4-DDB1-CDT2 E3 Ligase Regulates the Molecular Clock Activity by Promoting Ubiquitination-Dependent Degradation of the Mammalian CRY1. PLoS ONE. 2015;10:e0139725 pubmed publisher
  16. Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed publisher
  17. Gilda J, Ghosh R, Cheah J, West T, Bodine S, Gomes A. Western Blotting Inaccuracies with Unverified Antibodies: Need for a Western Blotting Minimal Reporting Standard (WBMRS). PLoS ONE. 2015;10:e0135392 pubmed publisher
  18. Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed publisher
  19. Lim G, Chua D, Basil A, Chan H, Chai C, Arumugam T, et al. Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-κB Pathway and Promotes Non-selective Mitophagy. J Biol Chem. 2015;290:16882-93 pubmed publisher
  20. Zhang H, Hu H, Greeley N, Jin J, Matthews A, Ohashi E, et al. STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13. Nat Commun. 2014;5:5798 pubmed publisher
  21. Baek J, Schmidt E, Viceconte N, Strandgren C, Pernold K, Richard T, et al. Expression of progerin in aging mouse brains reveals structural nuclear abnormalities without detectible significant alterations in gene expression, hippocampal stem cells or behavior. Hum Mol Genet. 2015;24:1305-21 pubmed publisher
  22. Nakamura M, Murray M, Lin W, Kusaka H, Dickson D. Optineurin immunoreactivity in neuronal and glial intranuclear inclusions in adult-onset neuronal intranuclear inclusion disease. Am J Neurodegener Dis. 2014;3:93-102 pubmed
  23. Haddock C, Blomenkamp K, Gautam M, James J, Mielcarska J, Gogol E, et al. PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes. PLoS ONE. 2014;9:e106371 pubmed publisher
  24. Xiong R, Siegel D, Ross D. Quinone-induced protein handling changes: implications for major protein handling systems in quinone-mediated toxicity. Toxicol Appl Pharmacol. 2014;280:285-95 pubmed publisher
  25. Ye W, Xing Y, Paustian C, van de Ven R, Moudgil T, Hilton T, et al. Cross-presentation of viral antigens in dribbles leads to efficient activation of virus-specific human memory T cells. J Transl Med. 2014;12:100 pubmed publisher
  26. Calco G, Stephens O, Donahue L, Tsui C, Pierchala B. CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains. J Biol Chem. 2014;289:7307-19 pubmed publisher
  27. Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed publisher
  28. Xue J, Lv D, Jiao S, Zhao W, Li X, Sun H, et al. pVHL mediates K63-linked ubiquitination of nCLU. PLoS ONE. 2012;7:e35848 pubmed publisher
  29. Paine S, Bedford L, Thorpe J, Mayer R, Cavey J, Bajaj N, et al. Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration. Neurosci Lett. 2009;460:205-8 pubmed publisher