This is a Validated Antibody Database (VAD) review about mouse Tyro3, based on 11 published articles (read how Labome selects the articles), using Tyro3 antibody in all methods. It is aimed to help Labome visitors find the most suited Tyro3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tyro3 synonym: AI323366; Brt; Dtk; Etk-2; Rse; Sky; TK19-2; Tif; etk2/tyro3; tk19-1

Abcam
domestic rabbit monoclonal (EPR4308)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 3a
Abcam Tyro3 antibody (Abcam, ab109231) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 3a). Clin Exp Immunol (2022) ncbi
R&D Systems
rat monoclonal (109646)
  • flow cytometry; mouse; loading ...; fig 1a
R&D Systems Tyro3 antibody (R&D, FAB759P) was used in flow cytometry on mouse samples (fig 1a). Cell Commun Signal (2018) ncbi
rat monoclonal (109646)
  • flow cytometry; mouse; loading ...; fig 2b
R&D Systems Tyro3 antibody (R&D Systems, FAB759P) was used in flow cytometry on mouse samples (fig 2b). J Clin Invest (2018) ncbi
domestic goat polyclonal
  • blocking or activating experiments; mouse; fig 1c
In order to assess the role of individual TAM family proteins during autophagy induction and hepatic inflammation, R&D Systems Tyro3 antibody (R&D Systems, AF759) was used in blocking or activating experiments on mouse samples (fig 1c). Autophagy (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2c
Invitrogen Tyro3 antibody (Invitrogen, PA5-14737) was used in western blot on mouse samples (fig 2c). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig s7b
Invitrogen Tyro3 antibody (ThermoFisher, PA5-40270) was used in western blot on mouse samples at 1:2000 (fig s7b). Nat Commun (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D38C6)
  • western blot; mouse; 1:1000; loading ...; fig s7b
Cell Signaling Technology Tyro3 antibody (Cell Signalling, 5585) was used in western blot on mouse samples at 1:1000 (fig s7b). Nat Commun (2020) ncbi
domestic rabbit monoclonal (D38C6)
  • western blot; human; loading ...; fig 4b
Cell Signaling Technology Tyro3 antibody (Cell Signaling, 5585) was used in western blot on human samples (fig 4b). Br J Cancer (2019) ncbi
domestic rabbit monoclonal (D38C6)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Tyro3 antibody (Cell Signaling, 5585) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (D38C6)
  • western blot; human; loading ...; fig 1a
Cell Signaling Technology Tyro3 antibody (Cell Signaling, 5585) was used in western blot on human samples (fig 1a). Mol Oncol (2017) ncbi
domestic rabbit monoclonal (D38C6)
  • western blot; mouse; loading ...; fig 4d
In order to engineer and characterize a second-generation, high-affinity AXL decoy receptor, Cell Signaling Technology Tyro3 antibody (CST, 5585) was used in western blot on mouse samples (fig 4d). J Clin Invest (2017) ncbi
domestic rabbit monoclonal (D38C6)
  • western blot; mouse; fig 1
Cell Signaling Technology Tyro3 antibody (Cell Signaling Technology, 5585S) was used in western blot on mouse samples (fig 1). Mol Biol Cell (2015) ncbi
Articles Reviewed
  1. Zheng L, Xu L, Hu F, Xue J, Bai M, Yao R, et al. Elevated expression of TAM receptor tyrosine kinase in synovial fluid and synovial tissue of rheumatoid arthritis. Clin Exp Immunol. 2022;209:270-279 pubmed publisher
  2. Al Zaeed N, Budai Z, Szondy Z, Sarang Z. TAM kinase signaling is indispensable for proper skeletal muscle regeneration in mice. Cell Death Dis. 2021;12:611 pubmed publisher
  3. Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed publisher
  4. Dufour F, Silina L, Neyret Kahn H, Moreno Vega A, Krucker C, Karboul N, et al. TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer. Br J Cancer. 2019;120:555-564 pubmed publisher
  5. Zhou J, Yang A, Wang Y, Chen F, Zhao Z, Davra V, et al. Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation. Cell Commun Signal. 2018;16:98 pubmed publisher
  6. Ubil E, Caskey L, Holtzhausen A, Hunter D, Story C, Earp H. Tumor-secreted Pros1 inhibits macrophage M1 polarization to reduce antitumor immune response. J Clin Invest. 2018;128:2356-2369 pubmed publisher
  7. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  8. Baumann C, Ullrich A, Torka R. GAS6-expressing and self-sustaining cancer cells in 3D spheroids activate the PDK-RSK-mTOR pathway for survival and drug resistance. Mol Oncol. 2017;11:1430-1447 pubmed publisher
  9. Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  10. Han J, Bae J, Choi C, Choi S, Kang H, Jo E, et al. Autophagy induced by AXL receptor tyrosine kinase alleviates acute liver injury via inhibition of NLRP3 inflammasome activation in mice. Autophagy. 2016;12:2326-2343 pubmed
  11. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed publisher