This is a Validated Antibody Database (VAD) review about mouse Tph2, based on 12 published articles (read how Labome selects the articles), using Tph2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tph2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tph2 synonym: AU043594; Ntph

Knockout validation
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig e6d
Abcam Tph2 antibody (Abcam, ab111828) was used in western blot knockout validation on mouse samples at 1:1000 (fig e6d). Nature (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1b
Invitrogen Tph2 antibody (Thermo Fisher, PA1-778) was used in immunohistochemistry - frozen section on mouse samples (fig 1b). Front Mol Neurosci (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:500; loading ...
In order to assess how plasticity in the midbrain dorsal raphe nucleus affects maternal behavior, Invitrogen Tph2 antibody (Thermo Scientific, PA1-778) was used in western blot on rat samples at 1:500. Psychoneuroendocrinology (2017) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 7.8
In order to study how variability in maternal care received among female rat siblings affects the siblings' later emotional and maternal behaviors, Invitrogen Tph2 antibody (Thermo Fisher Scientific, #PA1-778) was used in western blot on rat samples at 1:1000 (fig 7.8). Horm Behav (2016) ncbi
domestic rabbit polyclonal
In order to study hypoxia-induced chemosensory activity in the carotid body, Invitrogen Tph2 antibody (thermo, pa1-778) was used . Brain Res (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal (711-66)
  • immunocytochemistry; human; 1:2000; loading ...; fig 4a
Novus Biologicals Tph2 antibody (Novus, NB100-74555) was used in immunocytochemistry on human samples at 1:2000 (fig 4a). J Neural Transm (Vienna) (2021) ncbi
domestic rabbit polyclonal (711-66)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4a
Novus Biologicals Tph2 antibody (Novus, NB100-74555) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4a). Biomolecules (2020) ncbi
domestic rabbit polyclonal (711-66)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6b
In order to develop methods to identify the major projections to the mesolimbic dopamine circuit from the lateral hypothalamus and dorsal raphe nucleus, Novus Biologicals Tph2 antibody (Novus Biologicals, NB100-74555) was used in immunohistochemistry on mouse samples at 1:500 (fig 6b). J Neurosci (2017) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5d
Abcam Tph2 antibody (Abcam, ab111828) was used in immunohistochemistry - frozen section on mouse samples (fig 5d). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:500; fig 3d
Abcam Tph2 antibody (Abcam, ab111828) was used in immunohistochemistry on mouse samples at 1:500 (fig 3d). J Neurosci (2020) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig e6d
Abcam Tph2 antibody (Abcam, ab111828) was used in western blot knockout validation on mouse samples at 1:1000 (fig e6d). Nature (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D3E5I)
  • immunohistochemistry; mouse; 1:700; fig 3
In order to characterize the action of administered ciliary neurotrophic factor the dorsal vagal complex in mice, Cell Signaling Technology Tph2 antibody (Cell Signaling, 51124) was used in immunohistochemistry on mouse samples at 1:700 (fig 3). Front Neurosci (2016) ncbi
MilliporeSigma
mouse monoclonal (CL2990)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4g, 4h, 4i
MilliporeSigma Tph2 antibody (Sigma, AMAB91108) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4g, 4h, 4i). Transl Psychiatry (2021) ncbi
Articles Reviewed
  1. Tesoro Cruz E, Manuel Apolinar L, Oviedo N, Orozco Suarez S, Crespo Ramírez M, Bekker Mendez V, et al. Increase of 5-HT levels is induced both in mouse brain and HEK-293 cells following their exposure to a non-viral tryptophan hydroxylase construct. Transl Psychiatry. 2021;11:515 pubmed publisher
  2. Sahu M, Pazos Boubeta Y, Steinzeig A, Kaurinkoski K, Palmisano M, Borowecki O, et al. Depletion of TrkB Receptors From Adult Serotonergic Neurons Increases Brain Serotonin Levels, Enhances Energy Metabolism and Impairs Learning and Memory. Front Mol Neurosci. 2021;14:616178 pubmed publisher
  3. Yoo H, Yang S, Kim J, Yang E, Park H, Lee S, et al. Down-regulation of habenular calcium-dependent secretion activator 2 induces despair-like behavior. Sci Rep. 2021;11:3700 pubmed publisher
  4. Jansch C, Ziegler G, Forero A, Gredy S, W xe4 ldchen S, Vitale M, et al. Serotonin-specific neurons differentiated from human iPSCs form distinct subtypes with synaptic protein assembly. J Neural Transm (Vienna). 2021;128:225-241 pubmed publisher
  5. Uchida S, Soya S, Saito Y, Hirano A, Koga K, Tsuda M, et al. A discrete glycinergic neuronal population in the ventromedial medulla that induces muscle atonia during REM sleep and cataplexy in mice. J Neurosci. 2020;: pubmed publisher
  6. Lee J, Jeon Y, Park S, Son C. An Adrenalectomy Mouse Model Reflecting Clinical Features for Chronic Fatigue Syndrome. Biomolecules. 2020;10: pubmed publisher
  7. Farrelly L, Thompson R, Zhao S, Lepack A, Lyu Y, Bhanu N, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019;567:535-539 pubmed publisher
  8. Pomeranz L, Ekstrand M, Latcha K, Smith G, Enquist L, Friedman J. Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry. J Neurosci. 2017;37:4128-4144 pubmed publisher
  9. Holschbach M, Lonstein J. Motherhood and infant contact regulate neuroplasticity in the serotonergic midbrain dorsal raphe. Psychoneuroendocrinology. 2017;76:97-106 pubmed publisher
  10. Senzacqua M, Severi I, Perugini J, Acciarini S, Cinti S, Giordano A. Action of Administered Ciliary Neurotrophic Factor on the Mouse Dorsal Vagal Complex. Front Neurosci. 2016;10:289 pubmed publisher
  11. Ragan C, Harding K, Lonstein J. Associations among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical tryptophan hydroxylase-2 expression in female laboratory rats. Horm Behav. 2016;77:62-71 pubmed publisher
  12. Yokoyama T, Nakamuta N, Kusakabe T, Yamamoto Y. Sympathetic regulation of vascular tone via noradrenaline and serotonin in the rat carotid body as revealed by intracellular calcium imaging. Brain Res. 2015;1596:126-35 pubmed publisher