This is a Validated Antibody Database (VAD) review about mouse Tph1, based on 4 published articles (read how Labome selects the articles), using Tph1 antibody in all methods. It is aimed to help Labome visitors find the most suited Tph1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tph1 synonym: Tph; tryptophan 5-hydroxylase 1; tryptophan 5-monooxygenase 1

Abcam
rabbit monoclonal (EP1311Y)
  • immunohistochemistry - paraffin section; rat
  • western blot; human
Abcam Tph1 antibody (Abcam, ab52954) was used in immunohistochemistry - paraffin section on rat samples and in western blot on human samples . Physiol Rep (2015) ncbi
Cell Signaling Technology
rabbit monoclonal (D10C10)
  • western blot; mouse; 1:1000; loading ...; fig 1g
Cell Signaling Technology Tph1 antibody (Cell Signaling, 12339) was used in western blot on mouse samples at 1:1000 (fig 1g). Sci Rep (2018) ncbi
EMD Millipore
rabbit polyclonal
  • immunohistochemistry - frozen section; rat; 1:1000
In order to study hypoxia-induced chemosensory activity in the carotid body, EMD Millipore Tph1 antibody (chemicon, ab15570) was used in immunohistochemistry - frozen section on rat samples at 1:1000. Brain Res (2015) ncbi
Sigma-Aldrich
sheep polyclonal
  • immunohistochemistry; Mongolian gerbil; 1:1000; fig 1
In order to investigate differential regulation of serotonergic and GABAergic activity in the dorsal raphe nucleus by ON and OFF retinal ganglion cells, Sigma-Aldrich Tph1 antibody (Sigma-Aldrich, T8575) was used in immunohistochemistry on Mongolian gerbil samples at 1:1000 (fig 1). Sci Rep (2016) ncbi
Articles Reviewed
  1. Kim H, Kim Y, Choi W, Moon J, Hwang I, Kim K, et al. Generation of a highly efficient and tissue-specific tryptophan hydroxylase 1 knockout mouse model. Sci Rep. 2018;8:17642 pubmed publisher
  2. Zhang T, Huang L, Zhang L, Tan M, Pu M, Pickard G, et al. ON and OFF retinal ganglion cells differentially regulate serotonergic and GABAergic activity in the dorsal raphe nucleus. Sci Rep. 2016;6:26060 pubmed publisher
  3. Valdés Fuentes M, Vera Rivera G, De Ita Pérez D, Méndez I, Miranda M, Díaz Muñoz M. Effect of daytime-restricted feeding in the daily variations of liver metabolism and blood transport of serotonin in rat. Physiol Rep. 2015;3: pubmed publisher
  4. Yokoyama T, Nakamuta N, Kusakabe T, Yamamoto Y. Sympathetic regulation of vascular tone via noradrenaline and serotonin in the rat carotid body as revealed by intracellular calcium imaging. Brain Res. 2015;1596:126-35 pubmed publisher