This is a Validated Antibody Database (VAD) review about mouse Tnfsf11, based on 25 published articles (read how Labome selects the articles), using Tnfsf11 antibody in all methods. It is aimed to help Labome visitors find the most suited Tnfsf11 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tnfsf11 synonym: Ly109l; ODF; OPGL; RANKL; Trance; tumor necrosis factor ligand superfamily member 11; OPG ligand; TNF-related activation-induced cytokine; osteoclast differentiation factor; osteoprotegerin ligand; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa-B ligand; tumor necrosis factor-related activation-induced cytokine

Knockout validation
R&D Systems
rat monoclonal (88227)
  • immunohistochemistry knockout validation; mouse; fig 1
  • immunohistochemistry - frozen section; mouse; fig 1
In order to investigate how TRANCE on stromal cells contributes to the differentiation and maintenance of organized lymphoid aggregates in the small intestine, R&D Systems Tnfsf11 antibody (R&D, 88227) was used in immunohistochemistry knockout validation on mouse samples (fig 1) and in immunohistochemistry - frozen section on mouse samples (fig 1). J Immunol (2007) ncbi
Abcam
mouse monoclonal (12A668)
  • western blot; mouse; loading ...; fig 5a
Abcam Tnfsf11 antibody (Abcam, ab45039) was used in western blot on mouse samples (fig 5a). BMC Musculoskelet Disord (2017) ncbi
mouse monoclonal (12A668)
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1m
Abcam Tnfsf11 antibody (Abcam, 12A668) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1m). Arch Dermatol Res (2017) ncbi
mouse monoclonal (12A668)
  • western blot; mouse; fig 3
In order to infer a RANKL-dependent osteoclastogenesis after debridement of osteomyelitis coinciding with elevated B cells and simultaneously decreased osteogenesis, Abcam Tnfsf11 antibody (Abcam, ab45039) was used in western blot on mouse samples (fig 3). J Orthop Res (2017) ncbi
mouse monoclonal (12A668)
  • western blot; mouse; 1:1000; fig 4p
Abcam Tnfsf11 antibody (Abcam, ab45039) was used in western blot on mouse samples at 1:1000 (fig 4p). Nat Commun (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 6i
In order to study the contribution of IL-10 producing B cells on periodontal inflammation and bone loss in ligature-induced experimental periodontitis, Abcam Tnfsf11 antibody (Abcam, ab62516) was used in immunohistochemistry - paraffin section on mouse samples at 1:500 (fig 6i). Infect Immun (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 3
Abcam Tnfsf11 antibody (Abcam, ab183910) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 3). Mol Med Rep (2016) ncbi
mouse monoclonal (12A668)
  • immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1c
Abcam Tnfsf11 antibody (Abcam, AB45039) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig 1c). Oral Surg Oral Med Oral Pathol Oral Radiol (2015) ncbi
Invitrogen
rat monoclonal (IK22/5)
  • flow cytometry; mouse; loading ...; fig 6c
Invitrogen Tnfsf11 antibody (eBioscience, IK22/5) was used in flow cytometry on mouse samples (fig 6c). Eur J Immunol (2018) ncbi
rat monoclonal (IK22/5)
  • immunohistochemistry; mouse; 1:100; fig 4
Invitrogen Tnfsf11 antibody (eBioscience, 14-5952-8) was used in immunohistochemistry on mouse samples at 1:100 (fig 4). J Crohns Colitis (2017) ncbi
rat monoclonal (IK22/5)
  • immunohistochemistry - frozen section; mouse; fig 3a
In order to report the effects of aging on maturation of M cells, Invitrogen Tnfsf11 antibody (eBioscience, IK22/5) was used in immunohistochemistry - frozen section on mouse samples (fig 3a). Mucosal Immunol (2013) ncbi
rat monoclonal (IK22/5)
  • immunohistochemistry - frozen section; mouse; fig 1
  • immunohistochemistry; mouse; fig 1
In order to investigate how TRANCE on stromal cells contributes to the differentiation and maintenance of organized lymphoid aggregates in the small intestine, Invitrogen Tnfsf11 antibody (eBioscience, IK22/5) was used in immunohistochemistry - frozen section on mouse samples (fig 1) and in immunohistochemistry on mouse samples (fig 1). J Immunol (2007) ncbi
rat monoclonal (IK22/5)
  • flow cytometry; mouse; fig 2
In order to characterize and compare T helper 1 and 17 cells, Invitrogen Tnfsf11 antibody (eBiosciences, IK22/5) was used in flow cytometry on mouse samples (fig 2). J Leukoc Biol (2007) ncbi
BioLegend
rat monoclonal (IK22/5)
  • flow cytometry; mouse; loading ...; fig 9d
BioLegend Tnfsf11 antibody (BioLegend, IK22/5) was used in flow cytometry on mouse samples (fig 9d). J Exp Med (2018) ncbi
rat monoclonal (IK22/5)
  • flow cytometry; mouse
In order to study the involvement of RANKL in decidual M2 macrophage polarization, BioLegend Tnfsf11 antibody (Biolegend, 510005) was used in flow cytometry on mouse samples . Cell Death Dis (2017) ncbi
rat monoclonal (IK22/5)
  • flow cytometry; mouse; fig 3
BioLegend Tnfsf11 antibody (Biolegend, 510006) was used in flow cytometry on mouse samples (fig 3). J Clin Invest (2016) ncbi
rat monoclonal (IK22/5)
  • flow cytometry; mouse; tbl s1
In order to study the role of ICOS in group 2 innate lymphoid cell responses, BioLegend Tnfsf11 antibody (BioLegend, IK22/5) was used in flow cytometry on mouse samples (tbl s1). Biochem Biophys Res Commun (2015) ncbi
R&D Systems
goat polyclonal
  • immunohistochemistry - paraffin section; human; fig 1
In order to propose that RANK dictates WNT responsiveness to hormone-induced changes in adult mammary cells, R&D Systems Tnfsf11 antibody (R&D, AF462) was used in immunohistochemistry - paraffin section on human samples (fig 1). Stem Cell Reports (2015) ncbi
goat polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200
In order to study the function of RANKL/RANK signaling pathway during the salivary gland tumorigenicity, R&D Systems Tnfsf11 antibody (R&D Systems, AF462) was used in immunohistochemistry - paraffin section on mouse samples at 1:200. PLoS ONE (2015) ncbi
goat polyclonal
  • immunohistochemistry; mouse
R&D Systems Tnfsf11 antibody (R&D, AF462) was used in immunohistochemistry on mouse samples . PLoS ONE (2014) ncbi
rat monoclonal (88227)
  • immunohistochemistry knockout validation; mouse; fig 1
  • immunohistochemistry - frozen section; mouse; fig 1
In order to investigate how TRANCE on stromal cells contributes to the differentiation and maintenance of organized lymphoid aggregates in the small intestine, R&D Systems Tnfsf11 antibody (R&D, 88227) was used in immunohistochemistry knockout validation on mouse samples (fig 1) and in immunohistochemistry - frozen section on mouse samples (fig 1). J Immunol (2007) ncbi
Enzo Life Sciences
mouse monoclonal (12A380)
  • immunohistochemistry; rat; 1:800; fig 5a,5c
Enzo Life Sciences Tnfsf11 antibody (Alexis Biochemicals, ALX-804-244-C100) was used in immunohistochemistry on rat samples at 1:800 (fig 5a,5c). Mol Med Rep (2015) ncbi
mouse monoclonal (12A668)
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 2b
Enzo Life Sciences Tnfsf11 antibody (Enzo Life Sciences, 12A668) was used in immunohistochemistry - paraffin section on rat samples at 1:200 (fig 2b). J Biomed Mater Res B Appl Biomater (2015) ncbi
Active Motif
mouse monoclonal (12A380)
  • western blot; mouse
Active Motif Tnfsf11 antibody (Active Motif, 40940) was used in western blot on mouse samples . J Bone Miner Res (2011) ncbi
Cell Signaling Technology
rabbit polyclonal
  • western blot; human; fig 5
Cell Signaling Technology Tnfsf11 antibody (Cell Signaling Tech, 4816) was used in western blot on human samples (fig 5). Oncotarget (2015) ncbi
BD Biosciences
rat monoclonal (IK22-5)
  • flow cytometry; mouse; loading ...; fig 2-s1g
In order to propose that the ERK-AP-1 axis is important for translating TCR signal strength into proportional activation of downstream events, BD Biosciences Tnfsf11 antibody (BD Biosciences, 560296) was used in flow cytometry on mouse samples (fig 2-s1g). elife (2016) ncbi
rat monoclonal (IK22-5)
  • flow cytometry; mouse; 1:100
BD Biosciences Tnfsf11 antibody (BD Bioscience, IK22-5) was used in flow cytometry on mouse samples at 1:100. J Endod (2016) ncbi
Articles Reviewed
  1. Jones R, Cosway E, Willis C, White A, Jenkinson W, Fehling H, et al. Dynamic changes in intrathymic ILC populations during murine neonatal development. Eur J Immunol. 2018;48:1481-1491 pubmed publisher
  2. Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed publisher
  3. Chen X, Chen J, Xu D, Zhao S, Song H, Peng Y. Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs. BMC Musculoskelet Disord. 2017;18:423 pubmed publisher
  4. Meng Y, Zhou W, Jin L, Liu L, Chang K, Mei J, et al. RANKL-mediated harmonious dialogue between fetus and mother guarantees smooth gestation by inducing decidual M2 macrophage polarization. Cell Death Dis. 2017;8:e3105 pubmed publisher
  5. Matsuyama K, Mizutani Y, Takahashi T, Shu E, Kanoh H, Miyazaki T, et al. Enhanced dendritic cells and regulatory T cells in the dermis of porokeratosis. Arch Dermatol Res. 2017;309:749-756 pubmed publisher
  6. Wagner J, Jaurich H, Wallner C, Abraham S, Becerikli M, Dadras M, et al. Diminished bone regeneration after debridement of posttraumatic osteomyelitis is accompanied by altered cytokine levels, elevated B cell activity, and increased osteoclast activity. J Orthop Res. 2017;35:2425-2434 pubmed publisher
  7. Xu Z, Greenblatt M, Yan G, Feng H, Sun J, Lotinun S, et al. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nat Commun. 2017;8:14570 pubmed publisher
  8. Parnell E, Walch E, Lo D. Inducible Colonic M Cells Are Dependent on TNFR2 but Not Lt?r, Identifying Distinct Signalling Requirements for Constitutive Versus Inducible M Cells. J Crohns Colitis. 2017;11:751-760 pubmed publisher
  9. Yu P, Hu Y, Liu Z, Kawai T, Taubman M, Li W, et al. Local Induction of B Cell Interleukin-10 Competency Alleviates Inflammation and Bone Loss in Ligature-Induced Experimental Periodontitis in Mice. Infect Immun. 2017;85: pubmed publisher
  10. Allison K, Sajti E, Collier J, Gosselin D, Troutman T, Stone E, et al. Affinity and dose of TCR engagement yield proportional enhancer and gene activity in CD4+ T cells. elife. 2016;5: pubmed publisher
  11. He M, Wang J, Wang G, Tian Y, Jiang L, Ren Z, et al. Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis. Mol Med Rep. 2016;14:1054-60 pubmed publisher
  12. Li J, Chassaing B, Tyagi A, Vaccaro C, Luo T, Adams J, et al. Sex steroid deficiency-associated bone loss is microbiota dependent and prevented by probiotics. J Clin Invest. 2016;126:2049-63 pubmed publisher
  13. Francisconi C, Vieira A, Biguetti C, Glowacki A, Trombone A, Letra A, et al. Characterization of the Protective Role of Regulatory T Cells in Experimental Periapical Lesion Development and Their Chemoattraction Manipulation as a Therapeutic Tool. J Endod. 2016;42:120-6 pubmed publisher
  14. Pitari M, Rossi M, Amodio N, Botta C, Morelli E, Federico C, et al. Inhibition of miR-21 restores RANKL/OPG ratio in multiple myeloma-derived bone marrow stromal cells and impairs the resorbing activity of mature osteoclasts. Oncotarget. 2015;6:27343-58 pubmed publisher
  15. Joshi P, Waterhouse P, Kannan N, Narala S, Fang H, Di Grappa M, et al. RANK Signaling Amplifies WNT-Responsive Mammary Progenitors through R-SPONDIN1. Stem Cell Reports. 2015;5:31-44 pubmed publisher
  16. Szwarc M, Kommagani R, Jacob A, Dougall W, Ittmann M, Lydon J. Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS ONE. 2015;10:e0128467 pubmed publisher
  17. Kamachi F, Isshiki T, Harada N, Akiba H, Miyake S. ICOS promotes group 2 innate lymphoid cell activation in lungs. Biochem Biophys Res Commun. 2015;463:739-45 pubmed publisher
  18. Liu Z, Liu L, Kang C, Xie Q, Zhang B, Li Y. Effects of estrogen deficiency on microstructural changes in rat alveolar bone proper and periodontal ligament. Mol Med Rep. 2015;12:3508-3514 pubmed publisher
  19. Siar C, Tsujigiwa H, Ishak I, Hussin N, Nagatsuka H, Ng K. RANK, RANKL, and OPG in recurrent solid/multicystic ameloblastoma: their distribution patterns and biologic significance. Oral Surg Oral Med Oral Pathol Oral Radiol. 2015;119:83-91 pubmed publisher
  20. Bhattarai G, Lee Y, Yi H. Peroxisome proliferator activated receptor gamma loaded dental implant improves osteogenesis of rat mandible. J Biomed Mater Res B Appl Biomater. 2015;103:587-95 pubmed publisher
  21. Wang J, Eguchi K, Matsumoto S, Fujiu K, Komuro I, Nagai R, et al. The ?-3 polyunsaturated fatty acid, eicosapentaenoic acid, attenuates abdominal aortic aneurysm development via suppression of tissue remodeling. PLoS ONE. 2014;9:e96286 pubmed publisher
  22. Kobayashi A, Donaldson D, Erridge C, Kanaya T, Williams I, Ohno H, et al. The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice. Mucosal Immunol. 2013;6:1027-37 pubmed publisher
  23. Rousseau J, Escriou V, Lamoureux F, Brion R, Chesneau J, Battaglia S, et al. Formulated siRNAs targeting Rankl prevent osteolysis and enhance chemotherapeutic response in osteosarcoma models. J Bone Miner Res. 2011;26:2452-62 pubmed publisher
  24. Taylor R, Patel S, Lin E, Butler B, Lake J, Newberry R, et al. Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patches. J Immunol. 2007;178:5659-67 pubmed
  25. Nakae S, Iwakura Y, Suto H, Galli S. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol. 2007;81:1258-68 pubmed