This is a Validated Antibody Database (VAD) review about mouse Tmem173, based on 5 published articles (read how Labome selects the articles), using Tmem173 antibody in all methods. It is aimed to help Labome visitors find the most suited Tmem173 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tmem173 synonym: 2610307O08Rik; ERIS; MPYS; Mita; STING; stimulator of interferon genes protein; endoplasmic reticulum interferon stimulator; mediator of IRF3 activation; mitochondrial mediator of IRF3 activation; stimulator of interferon protein

Knockout validation
Proteintech Group
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
  • western blot knockout validation; mouse; 1:1000; fig 3
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, Proteintech Group Tmem173 antibody (Proteintech, 19851-1-AP) was used in western blot on human samples at 1:1000 (fig 3) and in western blot knockout validation on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
Abcam
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3c
  • immunocytochemistry; mouse; 1:50; loading ...; fig 5h, 6e
  • immunohistochemistry - frozen section; human; 1:50; loading ...; fig 2c
  • immunocytochemistry; human; 1:200; loading ...; fig 2k
  • western blot; human; 1:1000; loading ...; fig 2d, 2l
Abcam Tmem173 antibody (Abcam, ab92605) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3c), in immunocytochemistry on mouse samples at 1:50 (fig 5h, 6e), in immunohistochemistry - frozen section on human samples at 1:50 (fig 2c), in immunocytochemistry on human samples at 1:200 (fig 2k) and in western blot on human samples at 1:1000 (fig 2d, 2l). Nat Commun (2018) ncbi
Proteintech Group
rabbit polyclonal
  • immunocytochemistry; human; 1:500; loading ...; fig 6d
Proteintech Group Tmem173 antibody (Proteintech, 19851-1-AP) was used in immunocytochemistry on human samples at 1:500 (fig 6d). Nat Commun (2017) ncbi
rabbit polyclonal
  • western blot; human; loading ...; fig 1c
Proteintech Group Tmem173 antibody (Proteintech, 19851?C1-AP) was used in western blot on human samples (fig 1c). Proc Natl Acad Sci U S A (2017) ncbi
rabbit polyclonal
  • western blot; human; 1:1000; fig 3
  • western blot knockout validation; mouse; 1:1000; fig 3
In order to learn the requirement of palmitoylation at the Golgi by activation of STING, Proteintech Group Tmem173 antibody (Proteintech, 19851-1-AP) was used in western blot on human samples at 1:1000 (fig 3) and in western blot knockout validation on mouse samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
Abcam
rabbit polyclonal
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3c
  • immunocytochemistry; mouse; 1:50; loading ...; fig 5h, 6e
  • immunohistochemistry - frozen section; human; 1:50; loading ...; fig 2c
  • immunocytochemistry; human; 1:200; loading ...; fig 2k
  • western blot; human; 1:1000; loading ...; fig 2d, 2l
Abcam Tmem173 antibody (Abcam, ab92605) was used in western blot knockout validation on mouse samples at 1:1000 (fig 3c), in immunocytochemistry on mouse samples at 1:50 (fig 5h, 6e), in immunohistochemistry - frozen section on human samples at 1:50 (fig 2c), in immunocytochemistry on human samples at 1:200 (fig 2k) and in western blot on human samples at 1:1000 (fig 2d, 2l). Nat Commun (2018) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:100; fig 5a
Abcam Tmem173 antibody (Abcam, ab92605) was used in immunohistochemistry on mouse samples at 1:100 (fig 5a). Sci Rep (2016) ncbi
Articles Reviewed
  1. Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed publisher
  2. Xing J, Zhang A, Zhang H, Wang J, Li X, Zeng M, et al. TRIM29 promotes DNA virus infections by inhibiting innate immune response. Nat Commun. 2017;8:945 pubmed publisher
  3. Liu Y, Qu L, Liu Y, Roizman B, Zhou G. PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. Proc Natl Acad Sci U S A. 2017;114:E6902-E6911 pubmed publisher
  4. Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
  5. Li T, Cheng H, Yuan H, Xu Q, Shu C, Zhang Y, et al. Antitumor Activity of cGAMP via Stimulation of cGAS-cGAMP-STING-IRF3 Mediated Innate Immune Response. Sci Rep. 2016;6:19049 pubmed publisher