This is a Validated Antibody Database (VAD) review about mouse Timd4, based on 15 published articles (read how Labome selects the articles), using Timd4 antibody in all methods. It is aimed to help Labome visitors find the most suited Timd4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Timd4 synonym: B430010N18Rik; TIM-4; Tim4

Knockout validation
R&D Systems
domestic goat polyclonal
  • western blot knockout validation; mouse; loading ...; fig 4b
R&D Systems Timd4 antibody (R&D Systems, AF2826) was used in western blot knockout validation on mouse samples (fig 4b). Biochem Biophys Res Commun (2018) ncbi
BioLegend
rat monoclonal (RMT4-54)
  • mass cytometry; mouse; loading ...; fig s2
BioLegend Timd4 antibody (BioLegend, 130005) was used in mass cytometry on mouse samples (fig s2). Front Immunol (2021) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; fig 3c
BioLegend Timd4 antibody (Biolegend, RMT4-54) was used in flow cytometry on mouse samples (fig 3c). PLoS Pathog (2021) ncbi
rat monoclonal (RMT4-54)
  • mass cytometry; mouse; loading ...; fig s3
BioLegend Timd4 antibody (BioLegend, 130002) was used in mass cytometry on mouse samples (fig s3). EMBO J (2021) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; 1:200; loading ...; fig e6e
BioLegend Timd4 antibody (Biolegend, 130008) was used in flow cytometry on mouse samples at 1:200 (fig e6e). Nature (2019) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; 1:50; loading ...; fig 3e
BioLegend Timd4 antibody (BioLegend, RMT4-54) was used in flow cytometry on mouse samples at 1:50 (fig 3e). Front Immunol (2018) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; fig 2a
BioLegend Timd4 antibody (BioLegend, RMT4-54) was used in flow cytometry on mouse samples (fig 2a). J Exp Med (2018) ncbi
rat monoclonal (F31-5G3)
  • flow cytometry; mouse; loading ...; fig s1a
BioLegend Timd4 antibody (Biolegend, F31-5G3) was used in flow cytometry on mouse samples (fig s1a). Proc Natl Acad Sci U S A (2018) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; loading ...; fig 5c
BioLegend Timd4 antibody (BioLegend, RMT4-54) was used in flow cytometry on mouse samples (fig 5c). J Exp Med (2017) ncbi
rat monoclonal (RMT4-54)
  • flow cytometry; mouse; loading ...; fig s1
In order to research the role of Tim-1 and Tim-4 blockade in the atherosclerotic pathogenesis, BioLegend Timd4 antibody (Biolegend, RMT4-54) was used in flow cytometry on mouse samples (fig s1). Arterioscler Thromb Vasc Biol (2016) ncbi
Invitrogen
rat monoclonal (54 (RMT4-54))
  • flow cytometry; mouse; loading ...; fig 2g
In order to discover a mechanism that clears erythrocytes and recycles iron, Invitrogen Timd4 antibody (ebioscience, RMT 4-54) was used in flow cytometry on mouse samples (fig 2g). Nat Med (2016) ncbi
rat monoclonal (54 (RMT4-54))
  • flow cytometry; mouse; loading ...; tbl s6
In order to characterize and determine the origin of arterial macrophages, Invitrogen Timd4 antibody (eBiosciences, 46-5866-80) was used in flow cytometry on mouse samples (tbl s6). Nat Immunol (2016) ncbi
rat monoclonal (54 (RMT4-54))
  • flow cytometry; mouse
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4d
In order to discover a new tissue macrophage subset in the thymus that is dependent on transcription factor NR4A1 for development, Invitrogen Timd4 antibody (eBioscience, RMT4-54) was used in flow cytometry on mouse samples and in immunohistochemistry on mouse samples at 1:50 (fig 4d). Sci Rep (2015) ncbi
rat monoclonal (54 (RMT4-54))
  • flow cytometry; mouse; loading ...; fig 4e
In order to determine if specific B cell subsets or if B cell-derived interleukin-10 contributes to tolerance, Invitrogen Timd4 antibody (eBioscience, RMT4-54) was used in flow cytometry on mouse samples (fig 4e). Transplantation (2015) ncbi
R&D Systems
domestic goat polyclonal
  • western blot knockout validation; mouse; loading ...; fig 4b
R&D Systems Timd4 antibody (R&D Systems, AF2826) was used in western blot knockout validation on mouse samples (fig 4b). Biochem Biophys Res Commun (2018) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig s7
Abcam Timd4 antibody (Abcam, ab47637) was used in western blot on mouse samples at 1:500 (fig s7). Nat Commun (2016) ncbi
Articles Reviewed
  1. Félix I, Jokela H, Karhula J, Kotaja N, Savontaus E, Salmi M, et al. Single-Cell Proteomics Reveals the Defined Heterogeneity of Resident Macrophages in White Adipose Tissue. Front Immunol. 2021;12:719979 pubmed publisher
  2. Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed publisher
  3. Lagnado A, Leslie J, Ruchaud Sparagano M, Victorelli S, Hirsova P, Ogrodnik M, et al. Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner. EMBO J. 2021;40:e106048 pubmed publisher
  4. Ramachandran P, Dobie R, Wilson Kanamori J, Dora E, Henderson B, Luu N, et al. Resolving the fibrotic niche of human liver cirrhosis at single-cell level. Nature. 2019;575:512-518 pubmed publisher
  5. Mouhadeb O, Ben Shlomo S, Cohen K, Farkash I, Gruber S, Maharshak N, et al. Impaired COMMD10-Mediated Regulation of Ly6Chi Monocyte-Driven Inflammation Disrupts Gut Barrier Function. Front Immunol. 2018;9:2623 pubmed publisher
  6. Shaw T, Houston S, Wemyss K, Bridgeman H, Barbera T, Zangerle Murray T, et al. Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression. J Exp Med. 2018;215:1507-1518 pubmed publisher
  7. Panduro M, Benoist C, Mathis D. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:E2585-E2593 pubmed publisher
  8. Wakui H, Fuseya S, Suzuki R, Shimbo M, Okada R, Hamada M, et al. Incomplete clearance of apoptotic cells by core 1-derived O-glycan-deficient resident peritoneal macrophages. Biochem Biophys Res Commun. 2018;495:2017-2023 pubmed publisher
  9. A Gonzalez N, Quintana J, Garcia Silva S, Mazariegos M, González de la Aleja A, Nicolás Ávila J, et al. Phagocytosis imprints heterogeneity in tissue-resident macrophages. J Exp Med. 2017;214:1281-1296 pubmed publisher
  10. Theurl I, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, et al. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver. Nat Med. 2016;22:945-51 pubmed publisher
  11. Park S, Yun Y, Lim J, Kim M, Kim S, Kim J, et al. Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration. Nat Commun. 2016;7:10871 pubmed publisher
  12. Foks A, Engelbertsen D, Kuperwaser F, Alberts Grill N, Gonen A, Witztum J, et al. Blockade of Tim-1 and Tim-4 Enhances Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice. Arterioscler Thromb Vasc Biol. 2016;36:456-65 pubmed publisher
  13. Ensan S, Li A, Besla R, Degousee N, Cosme J, Roufaiel M, et al. Self-renewing resident arterial macrophages arise from embryonic CX3CR1(+) precursors and circulating monocytes immediately after birth. Nat Immunol. 2016;17:159-68 pubmed publisher
  14. Tacke R, Hilgendorf I, Garner H, Waterborg C, Park K, Nowyhed H, et al. The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus. Sci Rep. 2015;5:10055 pubmed publisher
  15. Lal G, Nakayama Y, Sethi A, Singh A, Burrell B, Kulkarni N, et al. Interleukin-10 From Marginal Zone Precursor B-Cell Subset Is Required for Costimulatory Blockade-Induced Transplantation Tolerance. Transplantation. 2015;99:1817-28 pubmed publisher