This is a Validated Antibody Database (VAD) review about mouse Tgoln2, based on 18 published articles (read how Labome selects the articles), using Tgoln2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tgoln2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tgoln2 synonym: TGN38B; TGN41; TGN46; Ttgn2; trans-Golgi network integral membrane protein 2

Abcam
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig s4c
Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig s4c). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (2F7.1)
  • immunocytochemistry; human; loading ...; fig 3f
Abcam Tgoln2 antibody (Abcam, 2F7.1) was used in immunocytochemistry on human samples (fig 3f). Nature (2017) ncbi
mouse monoclonal (2F7.1)
  • immunocytochemistry; human; fig 7a
In order to study amyloid precursor protein Tyr phosphorylation in mouse model of Alzheimer's disease, Abcam Tgoln2 antibody (Abcam, ab2809) was used in immunocytochemistry on human samples (fig 7a). Front Mol Neurosci (2017) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 4a
In order to find that CNS-specific snx6-knockout mice exhibit deficits in spatial learning and memory, accompanied with loss of spines from distal dendrites of hippocampal CA1 pyramidal cells, Abcam Tgoln2 antibody (Abcam, ab50595) was used in immunohistochemistry on mouse samples (fig 4a). elife (2017) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig 7d
Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunohistochemistry - frozen section on mouse samples (fig 7d). Cell Death Dis (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 7
Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunocytochemistry on human samples (fig 7). J Biol Chem (2017) ncbi
rabbit polyclonal
  • immunocytochemistry; human; 1:250; fig s3
In order to compare regulation of a Golgi-activated pool of Src during G2 by centrosomal maturation and Aurora-A recruitment, Abcam Tgoln2 antibody (Abcam, Ab50595) was used in immunocytochemistry on human samples at 1:250 (fig s3). Nat Commun (2016) ncbi
rabbit polyclonal
In order to determine control of clathrin coat recruitment to early endosomes for fast endocytic recycling by NECAP2, Abcam Tgoln2 antibody (Abcam, ab50595) was used . J Cell Sci (2016) ncbi
rabbit polyclonal
  • western blot; rat; fig 5b
In order to study the activity-driven interaction between presenilin 1 and synaptotagmin 1 and links to calcium, amyloid beta, and synapse, Abcam Tgoln2 antibody (Abcam, AB16059) was used in western blot on rat samples (fig 5b). BMC Biol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:200; fig 6e
In order to research Alzheimer's disease brain and neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau, Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunocytochemistry on mouse samples at 1:200 (fig 6e). Nat Commun (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; fig 3a
In order to elucidate the role of Asna1/TRC40 in endomembrane homeostasis and beta-cell function, Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunohistochemistry on mouse samples (fig 3a). Diabetes (2016) ncbi
rabbit polyclonal
  • immunohistochemistry; human
In order to identify and characterize the TALPID3 (KIAA0586) mutation in patients with Joubert syndrome, Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunohistochemistry on human samples . elife (2015) ncbi
rabbit polyclonal
  • immunocytochemistry; human; fig 5
Abcam Tgoln2 antibody (Abcam, ab50595) was used in immunocytochemistry on human samples (fig 5). elife (2015) ncbi
rabbit polyclonal
  • proximity ligation assay; human; 1:200; fig 3
Abcam Tgoln2 antibody (Abcam, ab50595) was used in proximity ligation assay on human samples at 1:200 (fig 3). PLoS Pathog (2015) ncbi
rabbit polyclonal
  • immunohistochemistry - free floating section; rat; 1:500
  • immunocytochemistry; rat; 1:500
In order to investigate the expression Ttyh1 protein in glia and activated astrocytes, Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunohistochemistry - free floating section on rat samples at 1:500 and in immunocytochemistry on rat samples at 1:500. Neurochem Res (2014) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:1000
Abcam Tgoln2 antibody (Abcam, ab16059) was used in immunocytochemistry on mouse samples at 1:1000. J Comp Neurol (2014) ncbi
rabbit polyclonal
  • western blot; mouse; fig 2c
In order to explore the underlying mechanisms of the variable expressivity of CEP290 in ciliopathies, Abcam Tgoln2 antibody (Abcam, ab16059) was used in western blot on mouse samples (fig 2c). Hum Mol Genet (2014) ncbi
Invitrogen
sheep polyclonal
  • immunocytochemistry; rat; 1:800; fig 9
In order to test if IRAP ligands regulate sst2A receptor trafficking and modulate limbic seizures, Invitrogen Tgoln2 antibody (Thermo Scientific, PA1-84496) was used in immunocytochemistry on rat samples at 1:800 (fig 9). J Neurosci (2015) ncbi
Articles Reviewed
  1. Maurya D, Bohm S, Alenius M. Hedgehog signaling regulates ciliary localization of mouse odorant receptors. Proc Natl Acad Sci U S A. 2017;114:E9386-E9394 pubmed publisher
  2. Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed publisher
  3. Poulsen E, Iannuzzi F, Rasmussen H, Maier T, Enghild J, Jørgensen A, et al. An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients. Front Mol Neurosci. 2017;10:59 pubmed publisher
  4. Niu Y, Dai Z, Liu W, Zhang C, Yang Y, Guo Z, et al. Ablation of SNX6 leads to defects in synaptic function of CA1 pyramidal neurons and spatial memory. elife. 2017;6: pubmed publisher
  5. Han F, Liu C, Zhang L, Zhou Y, Qin Y, Wang Y, et al. Globozoospermia and lack of acrosome formation in GM130-deficient mice. Cell Death Dis. 2017;8:e2532 pubmed publisher
  6. Li J, Wang Y, Matye D, Chavan H, Krishnamurthy P, Li F, et al. Sortilin 1 Modulates Hepatic Cholesterol Lipotoxicity in Mice via Functional Interaction with Liver Carboxylesterase 1. J Biol Chem. 2017;292:146-160 pubmed publisher
  7. Barretta M, Spano D, D Ambrosio C, Cervigni R, Scaloni A, Corda D, et al. Aurora-A recruitment and centrosomal maturation are regulated by a Golgi-activated pool of Src during G2. Nat Commun. 2016;7:11727 pubmed publisher
  8. Chamberland J, Antonow L, Dias Santos M, Ritter B. NECAP2 controls clathrin coat recruitment to early endosomes for fast endocytic recycling. J Cell Sci. 2016;129:2625-37 pubmed publisher
  9. Kuzuya A, Zoltowska K, Post K, Arimon M, Li X, Svirsky S, et al. Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta. BMC Biol. 2016;14:25 pubmed publisher
  10. Takeda S, Wegmann S, Cho H, DeVos S, Commins C, Roe A, et al. Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain. Nat Commun. 2015;6:8490 pubmed publisher
  11. Norlin S, Parekh V, Naredi P, Edlund H. Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport. Diabetes. 2016;65:110-9 pubmed publisher
  12. Stephen L, Tawamie H, Davis G, Tebbe L, Nürnberg P, Nürnberg G, et al. TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23). elife. 2015;4: pubmed publisher
  13. De Bundel D, Fafouri A, Csaba Z, Loyens E, Lebon S, El Ghouzzi V, et al. Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures. J Neurosci. 2015;35:11960-75 pubmed publisher
  14. Radoshevich L, Impens F, Ribet D, Quereda J, Nam Tham T, Nahori M, et al. ISG15 counteracts Listeria monocytogenes infection. elife. 2015;4: pubmed publisher
  15. Popa A, Zhang W, Harrison M, Goodner K, Kazakov T, Goodwin E, et al. Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015;11:e1004699 pubmed publisher
  16. Wiernasz E, Kaliszewska A, Brutkowski W, Bednarczyk J, Gorniak M, Kaza B, et al. Ttyh1 protein is expressed in glia in vitro and shows elevated expression in activated astrocytes following status epilepticus. Neurochem Res. 2014;39:2516-26 pubmed publisher
  17. Oetjen S, Mahlke C, Hermans Borgmeyer I, Hermey G. Spatiotemporal expression analysis of the growth factor receptor SorCS3. J Comp Neurol. 2014;522:3386-402 pubmed publisher
  18. Zhang Y, Seo S, Bhattarai S, Bugge K, Searby C, Zhang Q, et al. BBS mutations modify phenotypic expression of CEP290-related ciliopathies. Hum Mol Genet. 2014;23:40-51 pubmed publisher