This is a Validated Antibody Database (VAD) review about mouse Tgm2, based on 12 published articles (read how Labome selects the articles), using Tgm2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tgm2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tgm2 synonym: TG2; TGase2; tTG; tTGas

Knockout validation
Abcam
mouse monoclonal (CUB 7402)
  • immunocytochemistry knockout validation; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 1a
Abcam Tgm2 antibody (Abcam, Cub7402) was used in immunocytochemistry knockout validation on human samples (fig 6a) and in western blot on human samples (fig 1a). Amino Acids (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11A6)
  • western blot knockout validation; mouse; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
In order to examine the role of tissue transglutaminase 2 in the biogenesis of exosomes, Cell Signaling Technology Tgm2 antibody (Cell Signaling, D11A6) was used in western blot knockout validation on mouse samples (fig 4a) and in western blot on human samples (fig 4b). Biochim Biophys Acta (2016) ncbi
Abcam
domestic rabbit monoclonal (EP2957)
  • western blot; human; 1:1000; loading ...; fig 1g, 1h, 1i
Abcam Tgm2 antibody (Abcam, ab109200) was used in western blot on human samples at 1:1000 (fig 1g, 1h, 1i). J Exp Clin Cancer Res (2021) ncbi
mouse monoclonal (CUB 7402)
  • immunohistochemistry; human; 1:100; loading ...; fig 1a
Abcam Tgm2 antibody (Abcam, CUB7402) was used in immunohistochemistry on human samples at 1:100 (fig 1a). Oncogene (2021) ncbi
mouse monoclonal (CUB 7402)
  • immunocytochemistry knockout validation; human; loading ...; fig 6a
  • western blot; human; loading ...; fig 1a
Abcam Tgm2 antibody (Abcam, Cub7402) was used in immunocytochemistry knockout validation on human samples (fig 6a) and in western blot on human samples (fig 1a). Amino Acids (2021) ncbi
mouse monoclonal (CUB 7402)
  • western blot; rat; 1:500; loading ...; fig 1a
Abcam Tgm2 antibody (Abcam, ab2386) was used in western blot on rat samples at 1:500 (fig 1a). Science (2020) ncbi
mouse monoclonal (CUB 7402)
  • western blot; human; 1:1000; loading ...; fig 3a
Abcam Tgm2 antibody (Abcam, ab2386) was used in western blot on human samples at 1:1000 (fig 3a). PLoS ONE (2020) ncbi
mouse monoclonal (CUB 7402)
  • western blot; mouse; 1:500; loading ...; fig e2a
  • western blot; human; 1:500; loading ...; fig e2c, e2d
Abcam Tgm2 antibody (Abcam, ab2386) was used in western blot on mouse samples at 1:500 (fig e2a) and in western blot on human samples at 1:500 (fig e2c, e2d). Nature (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D11A6)
  • immunohistochemistry; mouse; 1:500; loading ...; fig 6b
Cell Signaling Technology Tgm2 antibody (Cell Signaling Technology, 3557S) was used in immunohistochemistry on mouse samples at 1:500 (fig 6b). JID Innov (2022) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot; human; 1:500; loading ...; fig 1a
Cell Signaling Technology Tgm2 antibody (Cell Signaling, D11A6) was used in western blot on human samples at 1:500 (fig 1a). Science (2020) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot; human; loading ...; fig 1b
Cell Signaling Technology Tgm2 antibody (Cell Signaling Technology, 3557) was used in western blot on human samples (fig 1b). J Biol Chem (2019) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot; mouse; loading ...; fig 4a
Cell Signaling Technology Tgm2 antibody (Cell Signaling Technology, 3557) was used in western blot on mouse samples (fig 4a). Cell Rep (2018) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot; mouse; 1:1000; loading ...; fig 1f
Cell Signaling Technology Tgm2 antibody (Cell Signaling, D11A6) was used in western blot on mouse samples at 1:1000 (fig 1f). Mol Biol Cell (2018) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot knockout validation; mouse; loading ...; fig 4a
  • western blot; human; loading ...; fig 4b
In order to examine the role of tissue transglutaminase 2 in the biogenesis of exosomes, Cell Signaling Technology Tgm2 antibody (Cell Signaling, D11A6) was used in western blot knockout validation on mouse samples (fig 4a) and in western blot on human samples (fig 4b). Biochim Biophys Acta (2016) ncbi
domestic rabbit monoclonal (D11A6)
  • western blot; mouse; 1:500; tbl 4
Cell Signaling Technology Tgm2 antibody (Cell Signaling Technology, 3557S) was used in western blot on mouse samples at 1:500 (tbl 4). PLoS ONE (2014) ncbi
Articles Reviewed
  1. Eggink L, Hoober J. Resolution of Eczema with Multivalent Peptides. JID Innov. 2022;2:100142 pubmed publisher
  2. Lei X, Cao K, Chen Y, Shen H, Liu Z, Qin H, et al. Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells. J Exp Clin Cancer Res. 2021;40:224 pubmed publisher
  3. Malkomes P, Lunger I, Oppermann E, Abou El Ardat K, Oellerich T, Günther S, et al. Transglutaminase 2 promotes tumorigenicity of colon cancer cells by inactivation of the tumor suppressor p53. Oncogene. 2021;40:4352-4367 pubmed publisher
  4. Fell S, Wang Z, Blanchard A, Nanthakumar C, Griffin M. Transglutaminase 2: a novel therapeutic target for idiopathic pulmonary fibrosis using selective small molecule inhibitors. Amino Acids. 2021;53:205-217 pubmed publisher
  5. Lepack A, Werner C, Stewart A, Fulton S, Zhong P, Farrelly L, et al. Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking. Science. 2020;368:197-201 pubmed publisher
  6. Potilinski M, Ortiz G, Salica J, Lopez E, Fernández Acquier M, Chuluyan E, et al. Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy. PLoS ONE. 2020;15:e0228895 pubmed publisher
  7. Jobin P, Solis N, Machado Y, Bell P, Kwon N, Kim S, et al. Matrix metalloproteinases inactivate the proinflammatory functions of secreted moonlighting tryptophanyl-tRNA synthetase. J Biol Chem. 2019;294:12866-12879 pubmed publisher
  8. Farrelly L, Thompson R, Zhao S, Lepack A, Lyu Y, Bhanu N, et al. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019;567:535-539 pubmed publisher
  9. D Eletto M, Rossin F, Occhigrossi L, Farrace M, Faccenda D, Desai R, et al. Transglutaminase Type 2 Regulates ER-Mitochondria Contact Sites by Interacting with GRP75. Cell Rep. 2018;25:3573-3581.e4 pubmed publisher
  10. Li R, Serrano J, Xing H, Lee T, Azizgolshani H, Zaman M, et al. Interstitial flow promotes macrophage polarization toward an M2 phenotype. Mol Biol Cell. 2018;29:1927-1940 pubmed publisher
  11. Diaz Hidalgo L, Altuntas S, Rossin F, D Eletto M, Marsella C, Farrace M, et al. Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions. Biochim Biophys Acta. 2016;1863:2084-92 pubmed publisher
  12. Menalled L, Kudwa A, Oakeshott S, Farrar A, Paterson N, Filippov I, et al. Genetic deletion of transglutaminase 2 does not rescue the phenotypic deficits observed in R6/2 and zQ175 mouse models of Huntington's disease. PLoS ONE. 2014;9:e99520 pubmed publisher