This is a Validated Antibody Database (VAD) review about mouse Tgfbr2, based on 26 published articles (read how Labome selects the articles), using Tgfbr2 antibody in all methods. It is aimed to help Labome visitors find the most suited Tgfbr2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tgfbr2 synonym: 1110020H15Rik; AU042018; DNIIR; RIIDN; TBR-II; TbetaR-II; TbetaRII

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (D-2)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5e
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot knockout validation on human samples at 1:1000 (fig 5e). Nat Commun (2021) ncbi
Abcam
domestic rabbit monoclonal (EPR23148-21)
  • western blot; mouse; 1:500; loading ...; fig 7b
Abcam Tgfbr2 antibody (Abcam, ab269279) was used in western blot on mouse samples at 1:500 (fig 7b). J Clin Invest (2022) ncbi
mouse monoclonal (MM0056-4F14)
  • immunocytochemistry; human; loading ...; fig 6
Abcam Tgfbr2 antibody (Abcam, ab78419) was used in immunocytochemistry on human samples (fig 6). Cancers (Basel) (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:2000; loading ...; fig 5c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in western blot on human samples at 1:2000 (fig 5c). Int J Oncol (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 2e, 5a
  • western blot; mouse; loading ...; fig 4h
Abcam Tgfbr2 antibody (Abcam, ab61213) was used in immunohistochemistry on human samples (fig 2c), in western blot on human samples (fig 2e, 5a) and in western blot on mouse samples (fig 4h). Clin Transl Med (2021) ncbi
mouse monoclonal (MM0056-4F14)
  • immunohistochemistry - paraffin section; human; 1:100; fig 2b
Abcam Tgfbr2 antibody (Abcam, ab78419) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2b). Pflugers Arch (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; loading ...; fig 4a
  • western blot; human; loading ...; fig 4c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in immunohistochemistry on human samples (fig 4a) and in western blot on human samples (fig 4c). Front Oncol (2020) ncbi
domestic rabbit polyclonal
  • other; mouse; 1:200; loading ...; fig 2c
Abcam Tgfbr2 antibody (Abcam, Ab61213) was used in other on mouse samples at 1:200 (fig 2c). Sci Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5c
Abcam Tgfbr2 antibody (Abcam, ab186838) was used in western blot on mouse samples (fig 5c). Proc Natl Acad Sci U S A (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 6c
In order to explore the roles of activated portal fibroblasts and myofibroblasts in the pathogenesis of liver fibrosis induced by bile duct ligation, Abcam Tgfbr2 antibody (Abcam, ab61213) was used in western blot on mouse samples at 1:500 (fig 6c). J Clin Invest (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; fig 1a, 1d
  • western blot; human; 1:1000; loading ...; fig 2b
Abcam Tgfbr2 antibody (Abcam, ab61213) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a, 1d) and in western blot on human samples at 1:1000 (fig 2b). Sci Rep (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2c
Abcam Tgfbr2 antibody (abcam, ab61213) was used in immunohistochemistry on mouse samples (fig 2c). Circulation (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:500; fig 5
Abcam Tgfbr2 antibody (Abcam, ab61213) was used in western blot on mouse samples at 1:500 (fig 5). PLoS ONE (2016) ncbi
mouse monoclonal (MM0056-4F14)
  • flow cytometry; human; 1:20; fig s10
In order to analyze propagation of oestrogen-responsive and oestrogen receptor-positive normal human breast cells in culture, Abcam Tgfbr2 antibody (Abcam, ab78419) was used in flow cytometry on human samples at 1:20 (fig s10). Nat Commun (2015) ncbi
mouse monoclonal (MM0056-4F14)
  • immunohistochemistry; human; fig 1
Abcam Tgfbr2 antibody (abcam, ab78419) was used in immunohistochemistry on human samples (fig 1). Mol Cancer (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (C-4)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 7a
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17791) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 7a). Mol Med Rep (2022) ncbi
mouse monoclonal (D-2)
  • western blot knockout validation; human; 1:1000; loading ...; fig 5e
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot knockout validation on human samples at 1:1000 (fig 5e). Nat Commun (2021) ncbi
mouse monoclonal (D-2)
  • western blot; mouse; 1:300; loading ...; fig 5a, 5c
  • western blot; human; 1:1000; loading ...; fig 5a
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot on mouse samples at 1:300 (fig 5a, 5c) and in western blot on human samples at 1:1000 (fig 5a). J Biol Chem (2021) ncbi
mouse monoclonal (E-6)
  • western blot; human; 1:500; fig 4
In order to examine TGFBR1 and TGFBR2 mutations in human vemurafenib-induced skin lesions and in sporadic cutaneous squamous cell carcinoma, Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, 17792) was used in western blot on human samples at 1:500 (fig 4). Nat Commun (2016) ncbi
mouse monoclonal (D-2)
  • western blot; human; 1:500
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17799) was used in western blot on human samples at 1:500. PLoS ONE (2015) ncbi
mouse monoclonal (E-6)
  • western blot; human; fig s2
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, sc-17792) was used in western blot on human samples (fig s2). Sci Rep (2015) ncbi
mouse monoclonal (D-2)
  • western blot; human; fig s3
Santa Cruz Biotechnology Tgfbr2 antibody (santa Cruz, sc-17799) was used in western blot on human samples (fig s3). Oncotarget (2015) ncbi
mouse monoclonal (C-4)
  • western blot; human; fig 3
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz, Sc-17791) was used in western blot on human samples (fig 3). Sci Rep (2015) ncbi
mouse monoclonal (E-6)
  • western blot; human; fig 2
Santa Cruz Biotechnology Tgfbr2 antibody (Santa Cruz Biotechnology, sc-17792) was used in western blot on human samples (fig 2). FASEB J (2014) ncbi
R&D Systems
domestic goat polyclonal
  • western blot; mouse; 1:400; loading ...; fig s2
R&D Systems Tgfbr2 antibody (R&D Systems, AF532) was used in western blot on mouse samples at 1:400 (fig s2). Nat Commun (2018) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6j
Invitrogen Tgfbr2 antibody (Invitrogen, PA5-36115) was used in western blot on mouse samples (fig 6j). Sci Adv (2021) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; human; 1:2500; loading ...; fig 4a
MilliporeSigma Tgfbr2 antibody (Sigma-Aldrich, SAB4504269) was used in western blot on human samples at 1:2500 (fig 4a). Mol Med Rep (2018) ncbi
Articles Reviewed
  1. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  2. Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
  3. Nakamura I, Asumda F, Moser C, Kang Y, Lai J, Roberts L. Sulfatase-2 Regulates Liver Fibrosis through the TGF-β Signaling Pathway. Cancers (Basel). 2021;13: pubmed publisher
  4. Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed publisher
  5. Huang J, Xiao R, Wang X, Khadka B, Fang Z, Yu M, et al. MicroRNA‑93 knockdown inhibits acute myeloid leukemia cell growth via inactivating the PI3K/AKT pathway by upregulating DAB2. Int J Oncol. 2021;59: pubmed publisher
  6. Gu P, Wang D, Zhang J, Wang X, Chen Z, Gu L, et al. Protective function of interleukin-22 in pulmonary fibrosis. Clin Transl Med. 2021;11:e509 pubmed publisher
  7. Bruce J, To K, Lui V, Chung G, Chan Y, Tsang C, et al. Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape. Nat Commun. 2021;12:4193 pubmed publisher
  8. Pan Y, Iejima D, Nakayama M, Suga A, Noda T, Kaur I, et al. Binding of Gtf2i-β/δ transcription factors to the ARMS2 gene leads to increased circulating HTRA1 in AMD patients and in vitro. J Biol Chem. 2021;296:100456 pubmed publisher
  9. Schilpp C, Lochbaum R, Braubach P, Jonigk D, Frick M, Dietl P, et al. TGF-β1 increases permeability of ciliated airway epithelia via redistribution of claudin 3 from tight junction into cell nuclei. Pflugers Arch. 2021;473:287-311 pubmed publisher
  10. Fu X, Qie J, Fu Q, Chen J, Jin Y, Ding Z. miR-20a-5p/TGFBR2 Axis Affects Pro-inflammatory Macrophages and Aggravates Liver Fibrosis. Front Oncol. 2020;10:107 pubmed publisher
  11. Voisin A, Damon Soubeyrand C, Bravard S, Saez F, Drevet J, Guiton R. Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis. Sci Rep. 2020;10:995 pubmed publisher
  12. Wang W, Chun H, Baek J, Sadik J, Shirazyan A, Razavi P, et al. The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019;116:15570-15579 pubmed publisher
  13. Lam J, van den Bosch M, Wegrzyn J, Parker J, Ibrahim R, Slowski K, et al. miR-143/145 differentially regulate hematopoietic stem and progenitor activity through suppression of canonical TGFβ signaling. Nat Commun. 2018;9:2418 pubmed publisher
  14. Li T, Zhao J. Knockdown of elF3a inhibits TGF??1?induced extracellular matrix protein expression in keloid fibroblasts. Mol Med Rep. 2018;17:4057-4061 pubmed publisher
  15. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed publisher
  16. Yang H, Zhang H, Zhong Y, Wang Q, Yang L, Kang H, et al. Concomitant underexpression of TGFBR2 and overexpression of hTERT are associated with poor prognosis in cervical cancer. Sci Rep. 2017;7:41670 pubmed publisher
  17. Zangi L, Oliveira M, Ye L, Ma Q, Sultana N, Hadas Y, et al. Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury. Circulation. 2017;135:59-72 pubmed publisher
  18. Cammareri P, Rose A, Vincent D, Wang J, Nagano A, Libertini S, et al. Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma. Nat Commun. 2016;7:12493 pubmed publisher
  19. Bianchi E, Boekelheide K, Sigman M, Lamb D, Hall S, Hwang K. Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-β Signaling Pathway. PLoS ONE. 2016;11:e0153968 pubmed publisher
  20. Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed publisher
  21. Bauer J, Ozden O, Akagi N, Carroll T, Principe D, Staudacher J, et al. Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer. Mol Cancer. 2015;14:182 pubmed publisher
  22. Lee J, Fricke F, Warnken U, Schnölzer M, Kopitz J, Gebert J. Reconstitution of TGFBR2-Mediated Signaling Causes Upregulation of GDF-15 in HCT116 Colorectal Cancer Cells. PLoS ONE. 2015;10:e0131506 pubmed publisher
  23. Rojas Fernandez A, Herhaus L, MacArtney T, Lachaud C, Hay R, Sapkota G. Rapid generation of endogenously driven transcriptional reporters in cells through CRISPR/Cas9. Sci Rep. 2015;5:9811 pubmed publisher
  24. Uppal A, Wightman S, Mallon S, Oshima G, Pitroda S, Zhang Q, et al. 14q32-encoded microRNAs mediate an oligometastatic phenotype. Oncotarget. 2015;6:3540-52 pubmed
  25. Rao R, Dhele N, Cheemadan S, Ketkar A, Jayandharan G, Palakodeti D, et al. Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming. Sci Rep. 2015;5:8229 pubmed publisher
  26. Holtzhausen A, Golzio C, How T, Lee Y, Schiemann W, Katsanis N, et al. Novel bone morphogenetic protein signaling through Smad2 and Smad3 to regulate cancer progression and development. FASEB J. 2014;28:1248-67 pubmed publisher