This is a Validated Antibody Database (VAD) review about mouse Tgfbr1, based on 20 published articles (read how Labome selects the articles), using Tgfbr1 antibody in all methods. It is aimed to help Labome visitors find the most suited Tgfbr1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tgfbr1 synonym: ALK5; AU017191; Alk-5; ESK2; TGFR-1; TbetaR-I; TbetaRI

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig s4g
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in western blot on mouse samples (fig s4g). Cell Death Dis (2022) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 6f
  • western blot; mouse; loading ...; fig 6j
Abcam Tgfbr1 antibody (Abcam, ab235178) was used in western blot on human samples (fig 6f) and in western blot on mouse samples (fig 6j). Sci Adv (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6c
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 6c). J Am Heart Assoc (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 4c
  • western blot; human; fig 7b
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in immunohistochemistry on mouse samples (fig 4c) and in western blot on human samples (fig 7b). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 1l
  • western blot; mouse; loading ...; fig 1k
  • western blot; human; 1:1000; loading ...; fig 1c
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in immunohistochemistry on mouse samples (fig 1l), in western blot on mouse samples (fig 1k) and in western blot on human samples at 1:1000 (fig 1c). Cell Death Dis (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 11c
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in western blot on mouse samples at 1:1000 (fig 11c). J Clin Invest (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6d
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in immunohistochemistry on mouse samples at 1:1000 (fig 6d). Nat Commun (2020) ncbi
domestic rabbit polyclonal
  • other; mouse; 1:100; loading ...; fig 2c
Abcam Tgfbr1 antibody (Abcam, Ab31013) was used in other on mouse samples at 1:100 (fig 2c). Sci Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:750; loading ...; fig 5e
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in western blot on human samples at 1:750 (fig 5e). Nat Commun (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; rat; loading ...; fig 6a
  • western blot; rat; 1:750; loading ...; fig 6a
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in immunoprecipitation on rat samples (fig 6a) and in western blot on rat samples at 1:750 (fig 6a). Cell Death Differ (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6d
Abcam Tgfbr1 antibody (Abcam, ab31013) was used in western blot on mouse samples (fig 6d). Basic Res Cardiol (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6c
In order to explore the roles of activated portal fibroblasts and myofibroblasts in the pathogenesis of liver fibrosis induced by bile duct ligation, Abcam Tgfbr1 antibody (Abcam, aB31013) was used in western blot on mouse samples (fig 6c). J Clin Invest (2017) ncbi
R&D Systems
rat monoclonal (141231)
  • flow cytometry; mouse; 1:10; loading ...; fig 6a
  • western blot; mouse; loading ...; fig 6b
In order to find that fibulin-6 knockdown fibroblasts affect TGF-beta dependent migration, stress fiber formation, cellular networking, and fibroblast wound contraction, R&D Systems Tgfbr1 antibody (R&D, MAB5871) was used in flow cytometry on mouse samples at 1:10 (fig 6a) and in western blot on mouse samples (fig 6b). Sci Rep (2017) ncbi
rat monoclonal (141231)
  • western blot; human; loading ...; fig 1a
  • western blot; mouse; loading ...; fig 1a
R&D Systems Tgfbr1 antibody (R&D, MAB5871) was used in western blot on human samples (fig 1a) and in western blot on mouse samples (fig 1a). Nat Commun (2016) ncbi
rat monoclonal (141231)
  • immunocytochemistry; mouse; 1:100; fig 3
In order to discuss the role of Beclin 1 in neurodegeneration, R&D Systems Tgfbr1 antibody (R&D Systems, MAB5871) was used in immunocytochemistry on mouse samples at 1:100 (fig 3). Mol Neurodegener (2015) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:500; loading ...; fig 7c
Invitrogen Tgfbr1 antibody (Invitrogen, PA540298) was used in western blot on mouse samples at 1:500 (fig 7c). J Clin Invest (2022) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; loading ...; fig 5c
Invitrogen Tgfbr1 antibody (Thermal scientific, PA5-40298) was used in western blot on rat samples at 1:1000 (fig 5c). Front Pharmacol (2020) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 4b
MilliporeSigma Tgfbr1 antibody (Sigma, SAB450958) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4b). Biomed Pharmacother (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:3000; loading ...; fig 4a
MilliporeSigma Tgfbr1 antibody (Sigma-Aldrich, SAB4502958) was used in western blot on human samples at 1:3000 (fig 4a). Mol Med Rep (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 2c
MilliporeSigma Tgfbr1 antibody (Sigma Aldrich, SAB4502958) was used in immunohistochemistry on mouse samples (fig 2c). Circulation (2017) ncbi
Articles Reviewed
  1. Wu T, Wang W, Shi G, Hao M, Wang Y, Yao M, et al. Targeting HIC1/TGF-β axis-shaped prostate cancer microenvironment restrains its progression. Cell Death Dis. 2022;13:624 pubmed publisher
  2. Humeres C, Shinde A, Hanna A, Alex L, Hern xe1 ndez S, Li R, et al. Smad7 effects on TGF-β and ErbB2 restrain myofibroblast activation and protect from postinfarction heart failure. J Clin Invest. 2022;132: pubmed publisher
  3. Xi Y, Li Y, Xu P, Li S, Liu Z, Tung H, et al. The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1. Sci Adv. 2021;7:eabg9241 pubmed publisher
  4. Srivastava S, Zhou H, Setia O, Dardik A, Fernandez Hernando C, GOODWIN J. Podocyte Glucocorticoid Receptors Are Essential for Glomerular Endothelial Cell Homeostasis in Diabetes Mellitus. J Am Heart Assoc. 2021;10:e019437 pubmed publisher
  5. Srivastava S, Zhou H, Setia O, Liu B, Kanasaki K, Koya D, et al. Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy. Nat Commun. 2021;12:2368 pubmed publisher
  6. Nishad R, Mukhi D, Singh A, Motrapu M, Chintala K, Tammineni P, et al. Growth hormone induces mitotic catastrophe of glomerular podocytes and contributes to proteinuria. Cell Death Dis. 2021;12:342 pubmed publisher
  7. Chen Y, Jhao P, Hung C, Wu Y, Lin S, Chiang W, et al. Endoplasmic reticulum protein TXNDC5 promotes renal fibrosis by enforcing TGF-β signaling in kidney fibroblasts. J Clin Invest. 2021;131: pubmed publisher
  8. Lee T, Yeh C, Lee Y, Shih Y, Chen Y, Hung C, et al. Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization. Nat Commun. 2020;11:4254 pubmed publisher
  9. Yang L, Han B, Zhang M, Wang Y, Tao K, Zhu M, et al. Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways. Front Pharmacol. 2020;11:165 pubmed publisher
  10. Voisin A, Damon Soubeyrand C, Bravard S, Saez F, Drevet J, Guiton R. Differential expression and localisation of TGF-β isoforms and receptors in the murine epididymis. Sci Rep. 2020;10:995 pubmed publisher
  11. Minuesa G, Albanese S, Xie W, Kazansky Y, Worroll D, Chow A, et al. Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 2019;10:2691 pubmed publisher
  12. He S, Nian F, Chen W, Yin L, Auchoybur M, Tao Z, et al. I-κB kinase-ε knockout protects against angiotensin II induced aortic valve thickening in apolipoprotein E deficient mice. Biomed Pharmacother. 2019;109:1287-1295 pubmed publisher
  13. Zhang R, Wu Y, Xie F, Zhong Y, Wang Y, Xu M, et al. RGMa mediates reactive astrogliosis and glial scar formation through TGF?1/Smad2/3 signaling after stroke. Cell Death Differ. 2018;25:1503-1516 pubmed publisher
  14. Li T, Zhao J. Knockdown of elF3a inhibits TGF??1?induced extracellular matrix protein expression in keloid fibroblasts. Mol Med Rep. 2018;17:4057-4061 pubmed publisher
  15. Wang Q, Yu Y, Zhang P, Chen Y, Li C, Chen J, et al. The crucial role of activin A/ALK4 pathway in the pathogenesis of Ang-II-induced atrial fibrosis and vulnerability to atrial fibrillation. Basic Res Cardiol. 2017;112:47 pubmed publisher
  16. Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed publisher
  17. Chowdhury A, Hasselbach L, Echtermeyer F, Jyotsana N, Theilmeier G, Herzog C. Fibulin-6 regulates pro-fibrotic TGF-β responses in neonatal mouse ventricular cardiac fibroblasts. Sci Rep. 2017;7:42725 pubmed publisher
  18. Zangi L, Oliveira M, Ye L, Ma Q, Sultana N, Hadas Y, et al. Insulin-Like Growth Factor 1 Receptor-Dependent Pathway Drives Epicardial Adipose Tissue Formation After Myocardial Injury. Circulation. 2017;135:59-72 pubmed publisher
  19. Yin S, Fan Y, Zhang H, Zhao Z, Hao Y, Li J, et al. Differential TGF? pathway targeting by miR-122 in humans and mice affects liver cancer metastasis. Nat Commun. 2016;7:11012 pubmed publisher
  20. O Brien C, Bonanno L, Zhang H, Wyss Coray T. Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5. Mol Neurodegener. 2015;10:69 pubmed publisher