This is a Validated Antibody Database (VAD) review about mouse Tbx5, based on 4 published articles (read how Labome selects the articles), using Tbx5 antibody in all methods. It is aimed to help Labome visitors find the most suited Tbx5 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Tbx5 synonym: T-box transcription factor TBX5; T-box protein 5

Santa Cruz Biotechnology
mouse monoclonal (A-4)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1c
Santa Cruz Biotechnology Tbx5 antibody (Santa Cruz Biotechnology Inc, sc-376952) was used in immunocytochemistry on mouse samples at 1:100 (fig 1c). Mol Med Rep (2018) ncbi
Invitrogen
rabbit polyclonal
  • immunocytochemistry; human
In order to determine the molecular mechanisms underlying Fbxo25-mediated ubiquitination of cardiac transcription factors, Invitrogen Tbx5 antibody (Invitrogen, 42-6500) was used in immunocytochemistry on human samples . Biochim Biophys Acta (2015) ncbi
rabbit polyclonal
  • immunohistochemistry; mouse; 1:500
  • western blot; mouse; 1:200
In order to investigate the mechanisms by which disruption of the Gata4 and Tbx5 interaction in the myocardium contributes to cardiac septation defects, Invitrogen Tbx5 antibody (Invitrogen, 426500) was used in immunohistochemistry on mouse samples at 1:500 and in western blot on mouse samples at 1:200. Hum Mol Genet (2014) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; fig 1
In order to identify Fbxo25 as a cardiac-specific ubiquitin E3 ligase that targets cardiac transcription factors, Invitrogen Tbx5 antibody (Invitrogen, 42-6500) was used in immunohistochemistry - frozen section on mouse samples (fig 1). Biochem Biophys Res Commun (2011) ncbi
Articles Reviewed
  1. Tian J, Wang R, Hou Q, Li M, Chen L, Deng X, et al. Optimization and enrichment of induced cardiomyocytes derived from mouse fibroblasts by reprogramming with cardiac transcription factors. Mol Med Rep. 2018;17:3912-3920 pubmed publisher
  2. Jeong H, Jung E, Sim Y, Kim S, Jang J, Hong K, et al. Fbxo25 controls Tbx5 and Nkx2-5 transcriptional activity to regulate cardiomyocyte development. Biochim Biophys Acta. 2015;1849:709-21 pubmed publisher
  3. Misra C, Chang S, Basu M, Huang N, Garg V. Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation. Hum Mol Genet. 2014;23:5025-35 pubmed publisher
  4. Jang J, Lee W, Lee J, Moon S, Kim C, Chung H. A novel Fbxo25 acts as an E3 ligase for destructing cardiac specific transcription factors. Biochem Biophys Res Commun. 2011;410:183-8 pubmed publisher