This is a Validated Antibody Database (VAD) review about mouse Sun2, based on 7 published articles (read how Labome selects the articles), using Sun2 antibody in all methods. It is aimed to help Labome visitors find the most suited Sun2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Sun2 synonym: B230369L08Rik; C030011B15; Unc84b; SUN domain-containing protein 2; protein unc-84 homolog B; sad1/unc-84 protein-like 2

Knockout validation
Abcam
rabbit monoclonal (EPR6557)
  • western blot knockout validation; mouse; 1:1000; fig s2
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
Abcam Sun2 antibody (Abcam, ab124916) was used in western blot knockout validation on mouse samples at 1:1000 (fig s2) and in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). J Cell Biol (2015) ncbi
Abcam
rabbit monoclonal (EPR6557)
  • western blot; human; 1:500; loading ...; fig s10c
Abcam Sun2 antibody (Abcam, ab124916) was used in western blot on human samples at 1:500 (fig s10c). Nature (2018) ncbi
rabbit monoclonal (EPR6557)
  • immunocytochemistry; human; 1:100; loading ...; fig s9a
In order to investigate the effect of actomyosin on cell nuclear morphology and genome stability, Abcam Sun2 antibody (Abcam, ab124916) was used in immunocytochemistry on human samples at 1:100 (fig s9a). Nat Commun (2017) ncbi
rabbit monoclonal (EPR6557)
  • western blot; hamsters; loading ...; fig s19a
In order to propose that local stresses applied to integrins propagate from the tensed actin cytoskeleton to the LINC complex and then through lamina-chromatin interactions to directly stretch chromatin and upregulate transcription, Abcam Sun2 antibody (Abcam, ab124916) was used in western blot on hamsters samples (fig s19a). Nat Mater (2016) ncbi
rabbit monoclonal (EPR6557)
  • western blot knockout validation; mouse; 1:1000; fig s2
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 1
Abcam Sun2 antibody (Abcam, ab124916) was used in western blot knockout validation on mouse samples at 1:1000 (fig s2) and in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 1). J Cell Biol (2015) ncbi
rabbit monoclonal (EPR6557)
  • immunocytochemistry; human
Abcam Sun2 antibody (Abcam, ab124916) was used in immunocytochemistry on human samples . Histochem Cell Biol (2014) ncbi
rabbit monoclonal (EPR6557)
  • western blot; human; loading ...; fig 2d
Abcam Sun2 antibody (Abcam, ab124916) was used in western blot on human samples (fig 2d). Sci Rep (2014) ncbi
ImmuQuest
mouse monoclonal ('LN43)
  • western blot; human; fig 1
ImmuQuest Sun2 antibody (Immuquest, LN43) was used in western blot on human samples (fig 1). Aging Cell (2015) ncbi
Articles Reviewed
  1. Frattini V, Pagnotta S, Tala -, Fan J, Russo M, Lee S, et al. A metabolic function of FGFR3-TACC3 gene fusions in cancer. Nature. 2018;553:222-227 pubmed publisher
  2. Takaki T, Montagner M, Serres M, Le Berre M, Russell M, Collinson L, et al. Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability. Nat Commun. 2017;8:16013 pubmed publisher
  3. Tajik A, Zhang Y, Wei F, Sun J, Jia Q, Zhou W, et al. Transcription upregulation via force-induced direct stretching of chromatin. Nat Mater. 2016;15:1287-1296 pubmed publisher
  4. Stewart R, Zubek A, Rosowski K, Schreiner S, Horsley V, King M. Nuclear-cytoskeletal linkages facilitate cross talk between the nucleus and intercellular adhesions. J Cell Biol. 2015;209:403-18 pubmed publisher
  5. Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed publisher
  6. Kalendová A, Kalasová I, Yamazaki S, Uličná L, Harata M, Hozak P. Nuclear actin filaments recruit cofilin and actin-related protein 3, and their formation is connected with a mitotic block. Histochem Cell Biol. 2014;142:139-52 pubmed publisher
  7. Shaiken T, Opekun A. Dissecting the cell to nucleus, perinucleus and cytosol. Sci Rep. 2014;4:4923 pubmed publisher