This is a Validated Antibody Database (VAD) review about mouse Stx6, based on 21 published articles (read how Labome selects the articles), using Stx6 antibody in all methods. It is aimed to help Labome visitors find the most suited Stx6 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Stx6 synonym: 2310039E05Rik; 2410005I16Rik; AA437559; AI415714; AI845861

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (C34B2)
  • western blot knockout validation; human; fig 2
  • immunocytochemistry; human; fig 1
Cell Signaling Technology Stx6 antibody (Cell Signaling, 2869) was used in western blot knockout validation on human samples (fig 2) and in immunocytochemistry on human samples (fig 1). Autophagy (2017) ncbi
Abcam
mouse monoclonal (3D10)
  • immunocytochemistry; mouse; loading ...; fig 5f
Abcam Stx6 antibody (Abcam, ab12370) was used in immunocytochemistry on mouse samples (fig 5f). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (EP7665)
  • western blot; rat; fig 2f
Abcam Stx6 antibody (Abcam, ab140607) was used in western blot on rat samples (fig 2f). Sci Rep (2015) ncbi
mouse monoclonal (3D10)
  • immunocytochemistry; mouse; fig 1
Abcam Stx6 antibody (Abcam, 3D10) was used in immunocytochemistry on mouse samples (fig 1). J Neurosci (2014) ncbi
Synaptic Systems
domestic rabbit polyclonal
  • immunocytochemistry; rat; loading ...
Synaptic Systems Stx6 antibody (Synaptic Systems, 110 062) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; rat; 1:250; loading ...; fig 5b
  • immunocytochemistry; rat; 1:150; loading ...; fig 6a
  • western blot; rat; 1:600; loading ...; fig 5a
In order to provide a mechanistic link between three early polarity events needed for neuronal polarity, Synaptic Systems Stx6 antibody (Synaptic System, 110,062) was used in immunoprecipitation on rat samples at 1:250 (fig 5b), in immunocytochemistry on rat samples at 1:150 (fig 6a) and in western blot on rat samples at 1:600 (fig 5a). Mol Neurobiol (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C34B2)
  • immunohistochemistry - paraffin section; human; loading ...; fig 5b
Cell Signaling Technology Stx6 antibody (Cell Signaling Technology, C34B2) was used in immunohistochemistry - paraffin section on human samples (fig 5b). Bone Rep (2020) ncbi
domestic rabbit monoclonal (C34B2)
  • immunocytochemistry; human; loading ...; fig 5
Cell Signaling Technology Stx6 antibody (Cell Signaling, 2869) was used in immunocytochemistry on human samples (fig 5). PLoS ONE (2016) ncbi
domestic rabbit monoclonal (C34B2)
  • western blot; human; loading ...; fig 4a
Cell Signaling Technology Stx6 antibody (Cell Signaling Technology, 2869S) was used in western blot on human samples (fig 4a). Sci Signal (2016) ncbi
domestic rabbit monoclonal (C34B2)
  • western blot knockout validation; human; fig 2
  • immunocytochemistry; human; fig 1
Cell Signaling Technology Stx6 antibody (Cell Signaling, 2869) was used in western blot knockout validation on human samples (fig 2) and in immunocytochemistry on human samples (fig 1). Autophagy (2017) ncbi
domestic rabbit monoclonal (C34B2)
  • immunocytochemistry; human; loading ...; fig 3d
Cell Signaling Technology Stx6 antibody (Cell Signaling, 2869) was used in immunocytochemistry on human samples (fig 3d). Cell Death Discov (2016) ncbi
domestic rabbit monoclonal (C34B2)
  • immunocytochemistry; mouse; loading ...; fig s16r
Cell Signaling Technology Stx6 antibody (Cell Signaling Technology, 2869) was used in immunocytochemistry on mouse samples (fig s16r). Nat Genet (2016) ncbi
domestic rabbit monoclonal (C34B2)
  • immunocytochemistry; mouse; 1:200-1:500; fig s4
Cell Signaling Technology Stx6 antibody (Cell Signaling Technology, 2869) was used in immunocytochemistry on mouse samples at 1:200-1:500 (fig s4). PLoS Genet (2015) ncbi
domestic rabbit monoclonal (C34B2)
  • western blot; human; fig 6
In order to assess adeno-associated virus transduction and its requirement for syntaxin 5-dependent retrograde transport to the trans-Golgi network, Cell Signaling Technology Stx6 antibody (Cell Signaling Technologies, C34B2) was used in western blot on human samples (fig 6). J Virol (2015) ncbi
BD Biosciences
mouse monoclonal (30/Syntaxin 6)
  • immunocytochemistry; mouse; loading ...; fig 1a
BD Biosciences Stx6 antibody (BD Transduction, 610635) was used in immunocytochemistry on mouse samples (fig 1a). J Cell Biol (2020) ncbi
mouse monoclonal (30/Syntaxin 6)
  • immunocytochemistry; mouse; 1:100; loading ...; fig s1j
BD Biosciences Stx6 antibody (BD Transduction, 610635) was used in immunocytochemistry on mouse samples at 1:100 (fig s1j). J Cell Sci (2018) ncbi
mouse monoclonal (30/Syntaxin 6)
  • immunocytochemistry; rat; fig 8
BD Biosciences Stx6 antibody (BD Biosciences, 610636) was used in immunocytochemistry on rat samples (fig 8). J Biol Chem (2016) ncbi
mouse monoclonal (30/Syntaxin 6)
  • western blot; human; fig 6b
BD Biosciences Stx6 antibody (BD Biosciences, 610635) was used in western blot on human samples (fig 6b). elife (2016) ncbi
mouse monoclonal (30/Syntaxin 6)
  • western blot; mouse
In order to test if bisecting GlcNAc would stabilize BACE1 protein upon oxidative stress, BD Biosciences Stx6 antibody (BD biosciences, 610635) was used in western blot on mouse samples . Biochem J (2016) ncbi
mouse monoclonal (30/Syntaxin 6)
  • immunohistochemistry; mouse; fig 5a
  • western blot; mouse; fig 5b
In order to elucidate the role of Asna1/TRC40 in endomembrane homeostasis and beta-cell function, BD Biosciences Stx6 antibody (BD Transduction Lab, 610635) was used in immunohistochemistry on mouse samples (fig 5a) and in western blot on mouse samples (fig 5b). Diabetes (2016) ncbi
mouse monoclonal (30/Syntaxin 6)
  • western blot; mouse; fig 1c
In order to study the effect of bisecting N-acetylglucosamine on beta-site amyloid precursor protein cleaving enzyme-1 (BACE1) activity, BD Biosciences Stx6 antibody (BD, 610635) was used in western blot on mouse samples (fig 1c). EMBO Mol Med (2015) ncbi
mouse monoclonal (30/Syntaxin 6)
  • immunohistochemistry - frozen section; mouse; 1:500
BD Biosciences Stx6 antibody (BD Biosciences, 610635) was used in immunohistochemistry - frozen section on mouse samples at 1:500. J Neurosci (2013) ncbi
Articles Reviewed
  1. Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  2. Zhang Z, Le K, La Placa D, Armstrong B, Miller M, Shively J. CXCR2 specific endocytosis of immunomodulatory peptide LL-37 in human monocytes and formation of LL-37 positive large vesicles in differentiated monoosteophils. Bone Rep. 2020;12:100237 pubmed publisher
  3. Alshafie W, Francis V, Bednarz K, Pan Y, Stroh T, McPherson P. Regulated resurfacing of a somatostatin receptor storage compartment fine-tunes pituitary secretion. J Cell Biol. 2020;219: pubmed publisher
  4. Fukushima M, Dasgupta D, Mauer A, Kakazu E, Nakao K, Malhi H. StAR-related lipid transfer domain 11 (STARD11)-mediated ceramide transport mediates extracellular vesicle biogenesis. J Biol Chem. 2018;293:15277-15289 pubmed publisher
  5. Singh V, Erady C, Balasubramanian N. Cell-matrix adhesion controls Golgi organization and function through Arf1 activation in anchorage-dependent cells. J Cell Sci. 2018;131: pubmed publisher
  6. Assadi G, Vesterlund L, Bonfiglio F, Mazzurana L, Cordeddu L, Schepis D, et al. Functional Analyses of the Crohn's Disease Risk Gene LACC1. PLoS ONE. 2016;11:e0168276 pubmed publisher
  7. Shahani N, Swarnkar S, Giovinazzo V, Morgenweck J, Bohn L, Scharager Tapia C, et al. RasGRP1 promotes amphetamine-induced motor behavior through a Rhes interaction network ("Rhesactome") in the striatum. Sci Signal. 2016;9:ra111 pubmed
  8. Nozawa T, Minowa Nozawa A, Aikawa C, Nakagawa I. The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. Autophagy. 2017;13:57-69 pubmed publisher
  9. Oksdath M, Guil A, Grassi D, Sosa L, Quiroga S. The Motor KIF5C Links the Requirements of Stable Microtubules and IGF-1 Receptor Membrane Insertion for Neuronal Polarization. Mol Neurobiol. 2017;54:6085-6096 pubmed publisher
  10. Jinesh G, Molina J, Huang L, Laing N, Mills G, Bar Eli M, et al. Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis. Cell Death Discov. 2016;2:16003 pubmed publisher
  11. Petrie M, Esquibel J, Kabachinski G, Maciuba S, Takahashi H, Edwardson J, et al. The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis. J Biol Chem. 2016;291:21257-21270 pubmed
  12. Deng H, Shi Y, Yang Y, Ahmeti K, Miller N, Huang C, et al. Identification of TMEM230 mutations in familial Parkinson's disease. Nat Genet. 2016;48:733-9 pubmed publisher
  13. Mkhikian H, Mortales C, Zhou R, Khachikyan K, Wu G, Haslam S, et al. Golgi self-correction generates bioequivalent glycans to preserve cellular homeostasis. elife. 2016;5: pubmed publisher
  14. Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed publisher
  15. Kizuka Y, Nakano M, Kitazume S, Saito T, Saido T, Taniguchi N. Bisecting GlcNAc modification stabilizes BACE1 protein under oxidative stress conditions. Biochem J. 2016;473:21-30 pubmed publisher
  16. Norlin S, Parekh V, Naredi P, Edlund H. Asna1/TRC40 Controls β-Cell Function and Endoplasmic Reticulum Homeostasis by Ensuring Retrograde Transport. Diabetes. 2016;65:110-9 pubmed publisher
  17. Seko Y, Fujimura T, Yao T, Taka H, Mineki R, Okumura K, et al. Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis. Sci Rep. 2015;5:13737 pubmed publisher
  18. Kizuka Y, Kitazume S, Fujinawa R, Saito T, Iwata N, Saido T, et al. An aberrant sugar modification of BACE1 blocks its lysosomal targeting in Alzheimer's disease. EMBO Mol Med. 2015;7:175-89 pubmed publisher
  19. Nonnenmacher M, Cintrat J, Gillet D, Weber T. Syntaxin 5-dependent retrograde transport to the trans-Golgi network is required for adeno-associated virus transduction. J Virol. 2015;89:1673-87 pubmed publisher
  20. Pinheiro P, Jansen A, de Wit H, Tawfik B, Madsen K, Verhage M, et al. The BAR domain protein PICK1 controls vesicle number and size in adrenal chromaffin cells. J Neurosci. 2014;34:10688-700 pubmed publisher
  21. Sadakata T, Kakegawa W, Shinoda Y, Hosono M, Katoh Semba R, Sekine Y, et al. CAPS1 deficiency perturbs dense-core vesicle trafficking and Golgi structure and reduces presynaptic release probability in the mouse brain. J Neurosci. 2013;33:17326-34 pubmed publisher