This is a Validated Antibody Database (VAD) review about mouse Stx1a, based on 28 published articles (read how Labome selects the articles), using Stx1a antibody in all methods. It is aimed to help Labome visitors find the most suited Stx1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Stx1a synonym: HPC-1

Synaptic Systems
mouse monoclonal (78.3)
  • western blot; mouse; 1:10,000; loading ...; fig 3e
Synaptic Systems Stx1a antibody (Synaptic Systems, 110111) was used in western blot on mouse samples at 1:10,000 (fig 3e). Biol Open (2021) ncbi
mouse monoclonal (78.2)
  • immunocytochemistry; rat; loading ...
Synaptic Systems Stx1a antibody (Synaptic Systems, 110 011) was used in immunocytochemistry on rat samples . Sci Adv (2021) ncbi
mouse monoclonal (78.2)
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 2a
  • western blot; mouse; loading ...; fig 1b
Synaptic Systems Stx1a antibody (Synaptic Systems, 110 011) was used in immunohistochemistry on mouse samples at 1:2000 (fig 2a) and in western blot on mouse samples (fig 1b). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; 1:1000; loading ...
Synaptic Systems Stx1a antibody (Synaptic Systems, 110 302) was used in immunohistochemistry on mouse samples at 1:1000. Physiol Rep (2020) ncbi
mouse monoclonal (78.2)
  • western blot; mouse; 1:1000; loading ...; fig 1
Synaptic Systems Stx1a antibody (Synaptic Systems, 110 011) was used in western blot on mouse samples at 1:1000 (fig 1). elife (2019) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; loading ...; fig 8b
Synaptic Systems Stx1a antibody (Synaptic Systems, 110 302) was used in immunohistochemistry on rat samples (fig 8b). EMBO J (2018) ncbi
mouse monoclonal (78.3)
  • immunohistochemistry; mouse; loading ...; fig 6a
Synaptic Systems Stx1a antibody (Synaptic Systems, 110,111) was used in immunohistochemistry on mouse samples (fig 6a). Acta Neuropathol Commun (2017) ncbi
mouse monoclonal (78.3)
  • western blot; mouse; 1:1000; fig 3i
Synaptic Systems Stx1a antibody (Synaptic Systems, 78.3) was used in western blot on mouse samples at 1:1000 (fig 3i). Nat Commun (2017) ncbi
mouse monoclonal (78.3)
  • western blot; mouse; loading ...; fig 2a
Synaptic Systems Stx1a antibody (Synaptic Systems, 110111) was used in western blot on mouse samples (fig 2a). elife (2017) ncbi
mouse monoclonal (78.2)
  • immunocytochemistry; rat; loading ...; fig 9
  • western blot; mouse; loading ...; fig 4
In order to generate an atoxic derivative of Botulism neurotoxin/C1 and assess whether it retains neuron-specific targeting without concomitant toxic host responses, Synaptic Systems Stx1a antibody (Synaptic Systems, 110011) was used in immunocytochemistry on rat samples (fig 9) and in western blot on mouse samples (fig 4). Sci Rep (2017) ncbi
mouse monoclonal (78.2)
  • western blot; rat; 1:2000; loading ...; fig 5a
In order to develop methods to study vesicle-associated proteins and exocytosis in stellate astrocytes, Synaptic Systems Stx1a antibody (Synaptic Systems, 110011) was used in western blot on rat samples at 1:2000 (fig 5a). J Gen Physiol (2017) ncbi
mouse monoclonal (78.2)
  • western blot; mouse; 1:1000; fig 3a
Synaptic Systems Stx1a antibody (SySy, 110011) was used in western blot on mouse samples at 1:1000 (fig 3a). EMBO Mol Med (2017) ncbi
mouse monoclonal (78.3)
  • immunoprecipitation; rat; fig 4a
  • western blot; rat; 1:2000; fig 3a
Synaptic Systems Stx1a antibody (Synaptic Systems, 110111) was used in immunoprecipitation on rat samples (fig 4a) and in western blot on rat samples at 1:2000 (fig 3a). PLoS ONE (2016) ncbi
mouse monoclonal (78.2)
  • immunocytochemistry; mouse; fig 6a
Synaptic Systems Stx1a antibody (Synaptic Systems, 110011) was used in immunocytochemistry on mouse samples (fig 6a). Mol Biol Cell (2016) ncbi
mouse monoclonal (78.2)
  • western blot; human; 1:10,000; fig 6B
Synaptic Systems Stx1a antibody (Synaptic System, 110011) was used in western blot on human samples at 1:10,000 (fig 6B). Acta Neuropathol Commun (2015) ncbi
mouse monoclonal (78.3)
  • western blot; rat; 1:250; fig 1
  • western blot; human; 1:100
Synaptic Systems Stx1a antibody (Synaptic Systems, 78.3) was used in western blot on rat samples at 1:250 (fig 1) and in western blot on human samples at 1:100. Neuroscience (2015) ncbi
mouse monoclonal (78.2)
  • immunohistochemistry; mouse; 1:100; fig 4
  • immunohistochemistry; rat; 1:100; fig 4
Synaptic Systems Stx1a antibody (Synaptic Systems, 78.2) was used in immunohistochemistry on mouse samples at 1:100 (fig 4) and in immunohistochemistry on rat samples at 1:100 (fig 4). Neuroscience (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (HPC-1)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...
Santa Cruz Biotechnology Stx1a antibody (Santa Cruz, sc-12736) was used in immunohistochemistry - paraffin section on human samples at 1:200. Int J Mol Sci (2020) ncbi
mouse monoclonal (HPC-1)
  • western blot; human; 1:1000; loading ...; fig 5c
Santa Cruz Biotechnology Stx1a antibody (Santa Cruz, SC12736) was used in western blot on human samples at 1:1000 (fig 5c). Proc Natl Acad Sci U S A (2018) ncbi
mouse monoclonal (HPC-1)
  • western blot; rat
Santa Cruz Biotechnology Stx1a antibody (Santa Cruz, SC 12736) was used in western blot on rat samples . Arq Bras Oftalmol (2015) ncbi
mouse monoclonal (HPC-1)
  • western blot; human; 1:600
Santa Cruz Biotechnology Stx1a antibody (Santa Cruz, sc-12736) was used in western blot on human samples at 1:600. PLoS ONE (2015) ncbi
mouse monoclonal (SP8)
  • western blot; rat
In order to test if alpha-synuclein modulates neurotransmitter release, Santa Cruz Biotechnology Stx1a antibody (Santa Cruz Biotechnology, sc-58299) was used in western blot on rat samples . J Neurosci (2014) ncbi
mouse monoclonal (HPC-1)
  • western blot; mouse; 1:2500
Santa Cruz Biotechnology Stx1a antibody (Santa Cruz, sc-12736) was used in western blot on mouse samples at 1:2500. J Comp Neurol (2013) ncbi
mouse monoclonal (HPC-1)
  • western blot; mouse
Santa Cruz Biotechnology Stx1a antibody (Santa, sc-12736) was used in western blot on mouse samples . Biochim Biophys Acta (2013) ncbi
Invitrogen
mouse monoclonal (SP6)
  • immunocytochemistry; human; 1:200; loading ...; tbl 1
In order to describe a method to produce human embryonic stem cell-derived Beta-like cells, Invitrogen Stx1a antibody (Thermo Fisher, MA5-17612) was used in immunocytochemistry on human samples at 1:200 (tbl 1). PLoS ONE (2016) ncbi
mouse monoclonal (SP6)
  • immunohistochemistry - paraffin section; human; 1:250
In order to study how proliferative restrictions of supporting cells are linked with DNA damage signaling, Invitrogen Stx1a antibody (LabVision/Thermo Scientific, #RM-9106, clone SP6) was used in immunohistochemistry - paraffin section on human samples at 1:250. Aging (Albany NY) (2014) ncbi
mouse monoclonal (SP6)
  • immunohistochemistry; rat; 1:300
In order to measure the expression of individual HDACs in the oligodendrocyte lineage during stroke-induced oligodendrogenesis, Invitrogen Stx1a antibody (Thermo Scientific, RM-9106) was used in immunohistochemistry on rat samples at 1:300. Neurochem Int (2014) ncbi
Abcam
domestic rabbit polyclonal
Abcam Stx1a antibody (Abcam, ab41453) was used . elife (2019) ncbi
Alomone Labs
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:200; loading ...; fig 2
  • western blot; rat; 1:40,000; loading ...; fig 1a
Alomone Labs Stx1a antibody (Alomone, ANR-002) was used in immunohistochemistry on rat samples at 1:200 (fig 2) and in western blot on rat samples at 1:40,000 (fig 1a). Front Mol Neurosci (2016) ncbi
Articles Reviewed
  1. Frei J, Brandenburg C, Nestor J, Hodzic D, Plachez C, McNeill H, et al. Postnatal expression profiles of atypical cadherin FAT1 suggest its role in autism. Biol Open. 2021;10: pubmed publisher
  2. Ivanova D, Dobson K, Gajbhiye A, Davenport E, Hacker D, Ultanir S, et al. Control of synaptic vesicle release probability via VAMP4 targeting to endolysosomes. Sci Adv. 2021;7: pubmed publisher
  3. Ishii C, Shibano N, Yamazaki M, Arima T, Kato Y, Ishii Y, et al. CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. Sci Rep. 2021;11:8656 pubmed publisher
  4. Arias Hervert E, Xu N, Njus M, Murphy G, Hou Y, Williams J, et al. Actions of Rab27B-GTPase on mammalian central excitatory synaptic transmission. Physiol Rep. 2020;8:e14428 pubmed publisher
  5. Kővári B, Turkevi Nagy S, Báthori Á, Fekete Z, Krenacs L. Syntaxin 1: A Novel Robust Immunophenotypic Marker of Neuroendocrine Tumors. Int J Mol Sci. 2020;21: pubmed publisher
  6. Raja M, Preobraschenski J, Del Olmo Cabrera S, Martínez Turrillas R, Jahn R, Pérez Otaño I, et al. Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts. elife. 2019;8: pubmed publisher
  7. Li Y, Li K, Hu W, Ojcius D, Fang J, Li S, et al. Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. elife. 2019;8: pubmed publisher
  8. Truckenbrodt S, Viplav A, Jähne S, Vogts A, Denker A, Wildhagen H, et al. Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission. EMBO J. 2018;37: pubmed publisher
  9. Wang Y, Figueiredo D, Sun X, Dong Z, Chen W, Cui W, et al. Controlling of glutamate release by neuregulin3 via inhibiting the assembly of the SNARE complex. Proc Natl Acad Sci U S A. 2018;115:2508-2513 pubmed publisher
  10. Hamada N, Iwamoto I, Tabata H, Nagata K. MUNC18-1 gene abnormalities are involved in neurodevelopmental disorders through defective cortical architecture during brain development. Acta Neuropathol Commun. 2017;5:92 pubmed publisher
  11. Lüningschrör P, Binotti B, Dombert B, Heimann P, Pérez Lara A, Slotta C, et al. Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease. Nat Commun. 2017;8:678 pubmed publisher
  12. Daniel J, Cooper B, Palvimo J, Zhang F, Brose N, Tirard M. Analysis of SUMO1-conjugation at synapses. elife. 2017;6: pubmed publisher
  13. Vazquez Cintron E, Beske P, Tenezaca L, Tran B, Oyler J, Glotfelty E, et al. Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery. Sci Rep. 2017;7:42923 pubmed publisher
  14. Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher
  15. Sambri I, D Alessio R, Ezhova Y, Giuliano T, Sorrentino N, Cacace V, et al. Lysosomal dysfunction disrupts presynaptic maintenance and restoration of presynaptic function prevents neurodegeneration in lysosomal storage diseases. EMBO Mol Med. 2017;9:112-132 pubmed publisher
  16. Massumi M, Pourasgari F, Nalla A, Batchuluun B, Nagy K, Neely E, et al. An Abbreviated Protocol for In Vitro Generation of Functional Human Embryonic Stem Cell-Derived Beta-Like Cells. PLoS ONE. 2016;11:e0164457 pubmed publisher
  17. Takeuchi S, Iwama S, Takagi H, Kiyota A, Nakashima K, Izumida H, et al. Tomosyn Negatively Regulates Arginine Vasopressin Secretion in Embryonic Stem Cell-Derived Neurons. PLoS ONE. 2016;11:e0164544 pubmed publisher
  18. Toft Bertelsen T, Ziomkiewicz I, Houy S, Pinheiro P, Sørensen J. Regulation of Ca2+ channels by SNAP-25 via recruitment of syntaxin-1 from plasma membrane clusters. Mol Biol Cell. 2016;27:3329-3341 pubmed
  19. Hussain S, Ringsevjen H, Egbenya D, Skjervold T, Davanger S. SNARE Protein Syntaxin-1 Colocalizes Closely with NMDA Receptor Subunit NR2B in Postsynaptic Spines in the Hippocampus. Front Mol Neurosci. 2016;9:10 pubmed publisher
  20. Benítez B, Cairns N, Schmidt R, Morris J, Norton J, Cruchaga C, et al. Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss. Acta Neuropathol Commun. 2015;3:73 pubmed publisher
  21. Dias A, Batista T, Roma L, Módulo C, Malki L, Dias L, et al. Insulin replacement restores the vesicular secretory apparatus in the diabetic rat lacrimal gland. Arq Bras Oftalmol. 2015;78:158-63 pubmed publisher
  22. Tsukamoto K, Ozeki C, Kohda T, Tsuji T. CRISPR/Cas9-Mediated Genomic Deletion of the Beta-1, 4 N-acetylgalactosaminyltransferase 1 Gene in Murine P19 Embryonal Carcinoma Cells Results in Low Sensitivity to Botulinum Neurotoxin Type C. PLoS ONE. 2015;10:e0132363 pubmed publisher
  23. Tao Cheng J, Pham A, Yang Y, Winters C, Gallant P, Reese T. Syntaxin 4 is concentrated on plasma membrane of astrocytes. Neuroscience. 2015;286:264-71 pubmed publisher
  24. Ronzitti G, Bucci G, Emanuele M, Leo D, Sotnikova T, Mus L, et al. Exogenous ?-synuclein decreases raft partitioning of Cav2.2 channels inducing dopamine release. J Neurosci. 2014;34:10603-15 pubmed publisher
  25. Laos M, Anttonen T, Kirjavainen A, af Hällström T, Laiho M, Pirvola U. DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells. Aging (Albany NY). 2014;6:496-510 pubmed
  26. Kassis H, Chopp M, Liu X, Shehadah A, Roberts C, Zhang Z. Histone deacetylase expression in white matter oligodendrocytes after stroke. Neurochem Int. 2014;77:17-23 pubmed publisher
  27. Eagleson K, Milner T, Xie Z, Levitt P. Synaptic and extrasynaptic location of the receptor tyrosine kinase met during postnatal development in the mouse neocortex and hippocampus. J Comp Neurol. 2013;521:3241-59 pubmed publisher
  28. Souza J, Vanzela E, Ribeiro R, Rezende L, de Oliveira C, Carneiro E, et al. Cholesterol reduction ameliorates glucose-induced calcium handling and insulin secretion in islets from low-density lipoprotein receptor knockout mice. Biochim Biophys Acta. 2013;1831:769-75 pubmed publisher