This is a Validated Antibody Database (VAD) review about mouse Stk11, based on 33 published articles (read how Labome selects the articles), using Stk11 antibody in all methods. It is aimed to help Labome visitors find the most suited Stk11 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Stk11 synonym: AA408040; Lkb1; Par-4; R75140

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (Ley 37D/G6)
  • western blot knockout validation; mouse; fig 4e
Santa Cruz Biotechnology Stk11 antibody (Santa, sc-32245) was used in western blot knockout validation on mouse samples (fig 4e). Diabetes (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (Ley 37D/G6)
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry; mouse; fig 7
Santa Cruz Biotechnology Stk11 antibody (Santa, Ley37 D/G6) was used in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry on mouse samples (fig 7). PLoS ONE (2011) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D60C5)
  • western blot; human; fig 1a
  • western blot knockout validation; mouse; fig s4b
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on human samples (fig 1a) and in western blot knockout validation on mouse samples (fig s4b). Nature (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D60C5)
  • western blot knockout validation; mouse; loading ...; fig 3e
In order to use transgenic mice to clarify the role of LKB1 in the maintenance of functional tight junction, Cell Signaling Technology Stk11 antibody (Cell Signaling, CST3047) was used in western blot knockout validation on mouse samples (fig 3e). Hepatology (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D60C5)
  • western blot knockout validation; mouse; 1:1000; fig 1
Cell Signaling Technology Stk11 antibody (Cell Signaling Technology, 3047) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Nat Commun (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (Ley 37D/G6)
  • immunohistochemistry; mouse; 1:50; loading ...; fig s3-1b
  • western blot; mouse; 1:500; loading ...; fig 1b
Santa Cruz Biotechnology Stk11 antibody (Sant Cruz Biotechnology, sc-32245) was used in immunohistochemistry on mouse samples at 1:50 (fig s3-1b) and in western blot on mouse samples at 1:500 (fig 1b). elife (2020) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; mouse; loading ...; fig 6b, 7a
Santa Cruz Biotechnology Stk11 antibody (Santa Cruz Biotechnology (Santa Cruz, CA), sc32245) was used in western blot on mouse samples (fig 6b, 7a). Pharmacol Res (2020) ncbi
mouse monoclonal (C-1)
  • western blot; mouse; loading ...; fig 6b, 7a
Santa Cruz Biotechnology Stk11 antibody (Santa Cruz Biotechnology (Santa Cruz, CA), sc-271924) was used in western blot on mouse samples (fig 6b, 7a). Pharmacol Res (2020) ncbi
mouse monoclonal (Ley 37D/G6)
  • immunocytochemistry; human; loading ...; fig 3a
  • western blot; human; loading ...; fig 3a
Santa Cruz Biotechnology Stk11 antibody (Santa, sc-32245) was used in immunocytochemistry on human samples (fig 3a) and in western blot on human samples (fig 3a). Theranostics (2018) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; rat; 1:2000
In order to show that NMDA receptors activate MARK/Par1 via protein kinase A in primary hippocampal neurons, Santa Cruz Biotechnology Stk11 antibody (Santa Cruz, sc32245) was used in western blot on rat samples at 1:2000. PLoS ONE (2015) ncbi
mouse monoclonal (Ley 37D/G6)
  • immunohistochemistry - paraffin section; human; 1:50
Santa Cruz Biotechnology Stk11 antibody (Santa Cruz, SC-32245) was used in immunohistochemistry - paraffin section on human samples at 1:50. J Exp Clin Cancer Res (2014) ncbi
mouse monoclonal (Ley 37D/G6)
  • immunohistochemistry - paraffin section; human; 1:100
  • immunoprecipitation; human
  • western blot; human; 1:1000
Santa Cruz Biotechnology Stk11 antibody (Santa Cruz, sc-32245) was used in immunohistochemistry - paraffin section on human samples at 1:100, in immunoprecipitation on human samples and in western blot on human samples at 1:1000. Int J Cancer (2014) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot knockout validation; mouse; fig 4e
Santa Cruz Biotechnology Stk11 antibody (Santa, sc-32245) was used in western blot knockout validation on mouse samples (fig 4e). Diabetes (2013) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry; mouse; fig 7
Santa Cruz Biotechnology Stk11 antibody (Santa, Ley37 D/G6) was used in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry on mouse samples (fig 7). PLoS ONE (2011) ncbi
Abcam
mouse monoclonal (Ley 37D/G6)
  • flow cytometry; human; 1:300; loading ...; fig 1c
  • western blot; human; loading ...; fig 2c
Abcam Stk11 antibody (Abcam, ab15095) was used in flow cytometry on human samples at 1:300 (fig 1c) and in western blot on human samples (fig 2c). J Biol Chem (2017) ncbi
mouse monoclonal (Ley 37D/G6)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Abcam Stk11 antibody (Abcam, ab15095) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal (Ley 37D/G6)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Abcam Stk11 antibody (Abcam, ab15095) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; mouse; loading ...; fig 3g
In order to test if LKB1 mutations contribute to cervical cancer initiation and progress, Abcam Stk11 antibody (Abcam, ab15095) was used in western blot on mouse samples (fig 3g). Oncogene (2017) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; human; 1:100; fig 4
Abcam Stk11 antibody (Abcam, ab15095) was used in western blot on human samples at 1:100 (fig 4). Chin J Cancer (2016) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; human; loading ...; fig 3a
Abcam Stk11 antibody (Abcam, ab15095) was used in western blot on human samples (fig 3a). Oncotarget (2015) ncbi
mouse monoclonal (Ley 37D/G6)
  • western blot; human; 1:1000
Abcam Stk11 antibody (Abcam, Ab15095) was used in western blot on human samples at 1:1000. Virology (2013) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D60C5)
  • western blot; human; 1:500-1:1000; loading ...; fig 3f
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on human samples at 1:500-1:1000 (fig 3f). J Biol Chem (2019) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; human; loading ...; fig 3a
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482) was used in western blot on human samples (fig 3a). Theranostics (2018) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; human; 1:1000; loading ...; fig s3d
In order to research the effect of methyl-beta-cyclodextrin on autophagy flux in Niemann-Pick C1-deficient cells, Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047s) was used in western blot on human samples at 1:1000 (fig s3d). Autophagy (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; human; 1:1000; loading ...; fig 8b
In order to research the roles of WIPI3 and WIPI4 in autophagy, Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on human samples at 1:1000 (fig 8b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; human; loading ...; fig 5a
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on human samples (fig 5a). Oncogene (2017) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; mouse; fig 5B
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482) was used in western blot on mouse samples (fig 5B). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; mouse; fig 5B
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on mouse samples (fig 5B). Sci Rep (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; human; loading ...; fig 5h
Cell Signaling Technology Stk11 antibody (Cell signaling, 3047) was used in western blot on human samples (fig 5h). Nat Commun (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; human; fig 1a
  • western blot knockout validation; mouse; fig s4b
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on human samples (fig 1a) and in western blot knockout validation on mouse samples (fig s4b). Nature (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • immunohistochemistry; mouse; loading ...; fig 1e
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in immunohistochemistry on mouse samples (fig 1e) and in western blot on mouse samples (fig 1c). PLoS Pathog (2017) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; mouse; loading ...; fig 1c
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482) was used in western blot on mouse samples (fig 1c). PLoS Pathog (2017) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot knockout validation; mouse; loading ...; fig 3e
In order to use transgenic mice to clarify the role of LKB1 in the maintenance of functional tight junction, Cell Signaling Technology Stk11 antibody (Cell Signaling, CST3047) was used in western blot knockout validation on mouse samples (fig 3e). Hepatology (2016) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; mouse; fig 4
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3047) was used in western blot on mouse samples (fig 4). Int J Mol Med (2016) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; mouse; fig 4
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482) was used in western blot on mouse samples (fig 4). Int J Mol Med (2016) ncbi
domestic rabbit monoclonal (D60C5)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
Cell Signaling Technology Stk11 antibody (Cell signaling, 3047) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Cell Rep (2015) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; rat; fig 5
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482S) was used in western blot on rat samples (fig 5). BMC Neurosci (2015) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; mouse; 1:1000; fig 5
Cell Signaling Technology Stk11 antibody (Cell Signaling, 3482) was used in western blot on mouse samples at 1:1000 (fig 5). Nat Cell Biol (2015) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; human; fig 3
Cell Signaling Technology Stk11 antibody (Cell signaling, 3482) was used in western blot on human samples (fig 3). Oncotarget (2015) ncbi
domestic rabbit monoclonal (C67A3)
  • western blot; human; fig 7
Cell Signaling Technology Stk11 antibody (Cell Signaling Technology, 3482) was used in western blot on human samples (fig 7). J Biol Chem (2015) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; rat
In order to test if Trp-His activates AMP-activated protein kinase to regulate the glucose transport system in skeletal muscle, Cell Signaling Technology Stk11 antibody (Cell Signaling Technology, 3047) was used in western blot on rat samples . FEBS Open Bio (2014) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot knockout validation; mouse; 1:1000; fig 1
Cell Signaling Technology Stk11 antibody (Cell Signaling Technology, 3047) was used in western blot knockout validation on mouse samples at 1:1000 (fig 1). Nat Commun (2014) ncbi
domestic rabbit monoclonal (D60C5)
  • western blot; rat; 1:1000
Cell Signaling Technology Stk11 antibody (Cell Signaling Technology, 3047S) was used in western blot on rat samples at 1:1000. PLoS ONE (2014) ncbi
Articles Reviewed
  1. Khayati K, Bhatt V, Hu Z, Fahumy S, Luo X, Guo J. Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival. elife. 2020;9: pubmed publisher
  2. Yang S, Ma C, Wu H, Zhang H, Yuan F, Yang G, et al. Tectorigenin attenuates diabetic nephropathy by improving vascular endothelium dysfunction through activating AdipoR1/2 pathway. Pharmacol Res. 2020;153:104678 pubmed publisher
  3. Wilson M, Jessen H, Saiardi A. The inositol hexakisphosphate kinases IP6K1 and -2 regulate human cellular phosphate homeostasis, including XPR1-mediated phosphate export. J Biol Chem. 2019;: pubmed publisher
  4. Zeng J, Liu W, Fan Y, He D, Li L. PrLZ increases prostate cancer docetaxel resistance by inhibiting LKB1/AMPK-mediated autophagy. Theranostics. 2018;8:109-123 pubmed publisher
  5. Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher
  6. Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed publisher
  7. Kumazoe M, Takai M, Hiroi S, Takeuchi C, Kadomatsu M, Nojiri T, et al. The FOXO3/PGC-1? signaling axis is essential for cancer stem cell properties of pancreatic ductal adenocarcinoma. J Biol Chem. 2017;292:10813-10823 pubmed publisher
  8. Choi E, Jung B, Lee S, Yoo H, Shin E, Ko H, et al. A clinical drug library screen identifies clobetasol propionate as an NRF2 inhibitor with potential therapeutic efficacy in KEAP1 mutant lung cancer. Oncogene. 2017;36:5285-5295 pubmed publisher
  9. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  10. Kemter E, Frohlich T, Arnold G, Wolf E, Wanke R. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970 pubmed publisher
  11. Li Z, Ivanov A, Su R, Gonzalez Pecchi V, Qi Q, Liu S, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nat Commun. 2017;8:14356 pubmed publisher
  12. Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
  13. Ganesan R, Hos N, Gutierrez S, Fischer J, Stepek J, Daglidu E, et al. Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy. PLoS Pathog. 2017;13:e1006227 pubmed publisher
  14. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  15. Zeng Q, Chen J, Li Y, Werle K, Zhao R, Quan C, et al. LKB1 inhibits HPV-associated cancer progression by targeting cellular metabolism. Oncogene. 2017;36:1245-1255 pubmed publisher
  16. Porat Shliom N, Tietgens A, Van Itallie C, Vitale Cross L, Jarnik M, Harding O, et al. Liver kinase B1 regulates hepatocellular tight junction distribution and function in vivo. Hepatology. 2016;64:1317-29 pubmed publisher
  17. Shinohara S, Gu Y, Yang Y, Furuta Y, Tanaka M, Yue X, et al. Ethanol extracts of chickpeas alter the total lipid content and expression levels of genes related to fatty acid metabolism in mouse 3T3-L1 adipocytes. Int J Mol Med. 2016;38:574-84 pubmed publisher
  18. Yao Y, Cui Y, Qiu X, Zhang L, Zhang W, Li H, et al. Attenuated LKB1-SIK1 signaling promotes epithelial-mesenchymal transition and radioresistance of non-small cell lung cancer cells. Chin J Cancer. 2016;35:50 pubmed publisher
  19. Ritho J, Arold S, Yeh E. A Critical SUMO1 Modification of LKB1 Regulates AMPK Activity during Energy Stress. Cell Rep. 2015;12:734-42 pubmed publisher
  20. Khan M, Dhammu T, Matsuda F, Singh A, Singh I. Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy. BMC Neurosci. 2015;16:42 pubmed publisher
  21. Yang S, Lin H, Chang V, Chen C, Liu Y, Wang J, et al. Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo. Oncotarget. 2015;6:23857-73 pubmed
  22. Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  23. Bernard L, Zhang H. MARK/Par1 Kinase Is Activated Downstream of NMDA Receptors through a PKA-Dependent Mechanism. PLoS ONE. 2015;10:e0124816 pubmed publisher
  24. Guo C, Hao C, Shao R, Fang B, Correa A, Hofstetter W, et al. RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer. Oncotarget. 2015;6:11114-24 pubmed
  25. Kemp M, Lindsey Boltz L, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem. 2015;290:12184-94 pubmed publisher
  26. Soga M, Ohashi A, Taniguchi M, Matsui T, Tsuda T. The di-peptide Trp-His activates AMP-activated protein kinase and enhances glucose uptake independently of insulin in L6 myotubes. FEBS Open Bio. 2014;4:898-904 pubmed publisher
  27. Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
  28. Kwon Y, Song P, Yoon J, Ghim J, Kim D, Kang B, et al. Xanthene derivatives increase glucose utilization through activation of LKB1-dependent AMP-activated protein kinase. PLoS ONE. 2014;9:e108771 pubmed publisher
  29. Li J, Liu J, Li P, Mao X, Li W, Yang J, et al. Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion. J Exp Clin Cancer Res. 2014;33:70 pubmed publisher
  30. Bouchekioua Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedER? is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed publisher
  31. Mack H, Munger K. The LKB1 tumor suppressor differentially affects anchorage independent growth of HPV positive cervical cancer cell lines. Virology. 2013;446:9-16 pubmed publisher
  32. Zhang W, Wang Q, Song P, Zou M. Liver kinase b1 is required for white adipose tissue growth and differentiation. Diabetes. 2013;62:2347-58 pubmed publisher
  33. Denison F, Smith L, Muckett P, O Hara L, Carling D, Woods A. LKB1 is an essential regulator of spermatozoa release during spermiation in the mammalian testis. PLoS ONE. 2011;6:e28306 pubmed publisher