This is a Validated Antibody Database (VAD) review about mouse Spast, based on 5 published articles (read how Labome selects the articles), using Spast antibody in all methods. It is aimed to help Labome visitors find the most suited Spast antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Spast synonym: Spg4; mKIAA1083; spastin; spastic paraplegia 4 homolog

Santa Cruz Biotechnology
mouse monoclonal (Sp 3G11/1)
  • immunocytochemistry; human; 1:50; fig S2a
Santa Cruz Biotechnology Spast antibody (Santa Cruz, sc-53443) was used in immunocytochemistry on human samples at 1:50 (fig S2a). Oncotarget (2016) ncbi
mouse monoclonal (Sp 3G11/1)
  • immunocytochemistry; African green monkey; 1:50
In order to investigate the relationships among abnormal spindle orientations, ectopic progenitors, and severe heterotopia in mouse and human, Santa Cruz Biotechnology Spast antibody (Santa Cruz Biotechnology, Sp 3G11:1) was used in immunocytochemistry on African green monkey samples at 1:50. Nat Neurosci (2014) ncbi
Proteintech Group
rabbit polyclonal
  • western blot; rat; 1:500; loading ...; fig 3a
In order to explore how laminin2 in the basement membrane modulates the blood testis barrier dynamics during spermatogenesis, Proteintech Group Spast antibody (Proteintech, 22792-1-AP) was used in western blot on rat samples at 1:500 (fig 3a). FASEB J (2017) ncbi
Sigma-Aldrich
mouse monoclonal (Sp 6C6)
  • western blot; mouse; fig 1
Sigma-Aldrich Spast antibody (Sigma, S7074) was used in western blot on mouse samples (fig 1). Mol Psychiatry (2016) ncbi
mouse monoclonal (Sp 6C6)
  • immunocytochemistry; human; 1:1000; fig 1
Sigma-Aldrich Spast antibody (Sigma, Sp 6C6) was used in immunocytochemistry on human samples at 1:1000 (fig 1). PLoS ONE (2014) ncbi
Articles Reviewed
  1. Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed publisher
  2. Kamranvar S, Gupta D, Huang Y, Gupta R, Johansson S. Integrin signaling via FAK-Src controls cytokinetic abscission by decelerating PLK1 degradation and subsequent recruitment of CEP55 at the midbody. Oncotarget. 2016;7:30820-30 pubmed publisher
  3. Sharoar M, Shi Q, Ge Y, He W, Hu X, Perry G, et al. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016;21:1263-71 pubmed publisher
  4. Goyal U, Renvoisé B, Chang J, Blackstone C. Spastin-interacting protein NA14/SSNA1 functions in cytokinesis and axon development. PLoS ONE. 2014;9:e112428 pubmed publisher
  5. Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed publisher