This is a Validated Antibody Database (VAD) review about mouse Smad4, based on 61 published articles (read how Labome selects the articles), using Smad4 antibody in all methods. It is aimed to help Labome visitors find the most suited Smad4 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Smad4 synonym: AW743858; D18Wsu70e; DPC4; Madh4

Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (B-8)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot knockout validation on human samples at 1:1000 (fig 1b). elife (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-8)
  • western blot knockout validation; mouse; fig 1
Santa Cruz Biotechnology Smad4 antibody (santa Cruz, sc-7966) was used in western blot knockout validation on mouse samples (fig 1). Cell Death Dis (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-8)
  • western blot knockout validation; human; fig 2
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, B8) was used in western blot knockout validation on human samples (fig 2). Nature (2015) ncbi
Abcam
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry knockout validation; mouse; 1:1000; loading ...; fig 4c
  • western blot knockout validation; mouse; 1:500; loading ...; fig 4a
Abcam Smad4 antibody (Abcam, 40759) was used in immunohistochemistry knockout validation on mouse samples at 1:1000 (fig 4c) and in western blot knockout validation on mouse samples at 1:500 (fig 4a). Am J Physiol Gastrointest Liver Physiol (2021) ncbi
Abcam
domestic rabbit monoclonal (EP618Y)
  • western blot knockout validation; mouse; loading ...; fig 2c
Abcam Smad4 antibody (Abcam, ab40759) was used in western blot knockout validation on mouse samples (fig 2c). J Biol Chem (2018) ncbi
Abcam
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 2d
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2d
Abcam Smad4 antibody (Abcam, ab40759) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 2d) and in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Int J Biol Sci (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 2a
  • immunocytochemistry; mouse; fig 1d
  • western blot; mouse; fig 1e
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc7966) was used in immunohistochemistry - paraffin section on mouse samples (fig 2a), in immunocytochemistry on mouse samples (fig 1d) and in western blot on mouse samples (fig 1e). Cancers (Basel) (2021) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1d
Santa Cruz Biotechnology Smad4 antibody (Santa, sc-7966) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig 1d). Nat Commun (2021) ncbi
mouse monoclonal (B-8)
  • western blot; human; 1:1000; loading ...; fig 6b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, 7966) was used in western blot on human samples at 1:1000 (fig 6b). Nat Commun (2021) ncbi
mouse monoclonal (B-8)
  • western blot knockout validation; human; 1:1000; loading ...; fig 1b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot knockout validation on human samples at 1:1000 (fig 1b). elife (2021) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; 1:1000; loading ...; fig 4e
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on mouse samples at 1:1000 (fig 4e). Nat Commun (2020) ncbi
mouse monoclonal (B-8)
  • proximity ligation assay; human; 1:200; loading ...; fig 3e
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in proximity ligation assay on human samples at 1:200 (fig 3e). elife (2020) ncbi
mouse monoclonal (B-8)
  • western blot; human; 1:1000; loading ...; fig 3e
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in western blot on human samples at 1:1000 (fig 3e). Nat Commun (2019) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 4c
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in western blot on human samples (fig 4c). Cell Adh Migr (2019) ncbi
mouse monoclonal (B-8)
  • western blot; human; 1:200; loading ...; fig 3b
Santa Cruz Biotechnology Smad4 antibody (Santa, sc7966) was used in western blot on human samples at 1:200 (fig 3b). Sci Rep (2019) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; loading ...; fig 5b
Santa Cruz Biotechnology Smad4 antibody (Santa, sc-7966) was used in western blot on mouse samples (fig 5b). Cancer Discov (2019) ncbi
mouse monoclonal (B-8)
  • other; human; loading ...; fig 4c
Santa Cruz Biotechnology Smad4 antibody (SantaCruz, sc-7966) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
mouse monoclonal (B-8)
  • western blot; human; 1:1000; loading ...; fig s3a
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on human samples at 1:1000 (fig s3a). Dev Cell (2017) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 4a
In order to investigate the effect off miR-509-5p and miR-1243 on gemcitabine efficacy in pancreatic cancer and its mechanism, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on human samples (fig 4a). Sci Rep (2017) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; fig s16
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, B-8) was used in western blot on mouse samples (fig s16). Cell Death Dis (2017) ncbi
mouse monoclonal
  • western blot; mouse; fig s16
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, B-8) was used in western blot on mouse samples (fig s16). Cell Death Dis (2017) ncbi
mouse monoclonal (B-8)
  • reverse phase protein lysate microarray; human; loading ...; fig st6
In order to characterize the molecular identity of uterine carcinosarcomas., Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in reverse phase protein lysate microarray on human samples (fig st6). Cancer Cell (2017) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig s1b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, B8) was used in western blot on human samples (fig s1b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig s1b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, B8) was used in western blot on human samples (fig s1b). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1a
Santa Cruz Biotechnology Smad4 antibody (Santa-Cruz, B-8) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1a). Biol Open (2017) ncbi
mouse monoclonal
  • immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig 1a
Santa Cruz Biotechnology Smad4 antibody (Santa-Cruz, B-8) was used in immunohistochemistry - frozen section on mouse samples at 1:50 (fig 1a). Biol Open (2017) ncbi
mouse monoclonal (B-8)
  • reverse phase protein lysate microarray; human; loading ...; fig 3a
In order to describe the features of 228 primary cervical cancers, Santa Cruz Biotechnology Smad4 antibody (SantaCruz, sc-7966) was used in reverse phase protein lysate microarray on human samples (fig 3a). Nature (2017) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry; human; loading ...; fig s1h
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in immunohistochemistry on human samples (fig s1h). Nature (2017) ncbi
mouse monoclonal (B-8)
  • chromatin immunoprecipitation; mouse; loading ...; fig 3h
Santa Cruz Biotechnology Smad4 antibody (SantaCruz, sc-7966X) was used in chromatin immunoprecipitation on mouse samples (fig 3h). J Immunol (2017) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; loading ...; fig 4b
In order to determine the effect of the Mstn(Cmpt-dl1Abc) mutation or the Compact genetic background on morphology, metabolism and signaling, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on mouse samples (fig 4b). Am J Physiol Endocrinol Metab (2017) ncbi
mouse monoclonal (B-8)
  • flow cytometry; mouse; fig 1a
In order to research the role of Smad4 during skeletal muscle regeneration, Santa Cruz Biotechnology Smad4 antibody (SantaCruz, sc-7966) was used in flow cytometry on mouse samples (fig 1a). elife (2016) ncbi
mouse monoclonal (B-8)
  • western blot; human; loading ...; fig 7e
In order to propose that DLX1 modulates FOXM1 signaling to promote cancer aggressiveness via TGF-beta/SMAD4 signaling in high-grade serous ovarian cancer cells, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on human samples (fig 7e). Oncogene (2017) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry; human; 1:1000; loading ...; fig 4a
  • western blot; human; 1:200; loading ...; fig 3a
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in immunohistochemistry on human samples at 1:1000 (fig 4a) and in western blot on human samples at 1:200 (fig 3a). Oncotarget (2016) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; human; 1:400; fig s1
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in immunohistochemistry - paraffin section on human samples at 1:400 (fig s1). EMBO Mol Med (2016) ncbi
mouse monoclonal (B-8)
  • western blot; human; 1:1000; fig 3
In order to study regulation by ADP-ribosylation of bone morphogenetic protein signaling, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on human samples at 1:1000 (fig 3). J Biol Chem (2016) ncbi
mouse monoclonal (B-8)
  • western blot; human; fig 2
In order to elucidate the contributions of Smad2 and Smad3 to TGFbeta signaling, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in western blot on human samples (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (B-8)
  • immunocytochemistry; human; fig 5
  • western blot; human; fig 4
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in immunocytochemistry on human samples (fig 5) and in western blot on human samples (fig 4). Nat Genet (2016) ncbi
mouse monoclonal
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Smad4 antibody (SCBT, B-8) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (B-8)
  • other; human; loading ...; fig st1
In order to use size exclusion chromatography-microsphere-based affinity proteomics to study clinical samples obtained from pediatric acute leukemia patients, Santa Cruz Biotechnology Smad4 antibody (SCBT, B-8) was used in other on human samples (fig st1). Mol Cell Proteomics (2016) ncbi
mouse monoclonal (B-8)
  • western blot knockout validation; mouse; fig 1
Santa Cruz Biotechnology Smad4 antibody (santa Cruz, sc-7966) was used in western blot knockout validation on mouse samples (fig 1). Cell Death Dis (2015) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; mouse
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in immunohistochemistry - paraffin section on mouse samples . Reprod Sci (2016) ncbi
mouse monoclonal (B-8)
  • proximity ligation assay; mouse; fig s12
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in proximity ligation assay on mouse samples (fig s12). Nat Commun (2015) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry; human; 1:250; loading ...; fig 1e
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, SC-7966) was used in immunohistochemistry on human samples at 1:250 (fig 1e). BMC Cancer (2015) ncbi
mouse monoclonal (B-8)
  • western blot knockout validation; human; fig 2
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, B8) was used in western blot knockout validation on human samples (fig 2). Nature (2015) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, SC-7966) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1). World J Surg Oncol (2015) ncbi
mouse monoclonal (B-8)
  • western blot; human
In order to evaluate the effect of aspirin in mesenchymal to epithelial transition, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnologies, sc-7966) was used in western blot on human samples . Lab Invest (2015) ncbi
mouse monoclonal (B-8)
  • western blot; human; fig s5b
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on human samples (fig s5b). Breast Cancer Res (2015) ncbi
mouse monoclonal (B-8)
  • western blot; human
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in western blot on human samples . Biochim Biophys Acta (2015) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry; human; 1:400
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in immunohistochemistry on human samples at 1:400. Br J Cancer (2015) ncbi
mouse monoclonal (B-8)
  • chromatin immunoprecipitation; mouse; 2.0 ug
In order to determine how TGF-beta1-induced FGF-2 expression is regulated in prostate stromal fibroblasts and mouse embryo fibroblasts null for Smad2 and Smad3, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, B8) was used in chromatin immunoprecipitation on mouse samples at 2.0 ug. Am J Clin Exp Urol (2014) ncbi
mouse monoclonal (B-8)
  • western blot; mouse; 1:1000; fig 1c
In order to show that Basonuclin-1 regulates TGF-beta1-induced epithelial dedifferentiation of mammary epithelial cells, Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in western blot on mouse samples at 1:1000 (fig 1c). Oncogene (2015) ncbi
mouse monoclonal (B-8)
  • immunohistochemistry - paraffin section; human; 1:200
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966) was used in immunohistochemistry - paraffin section on human samples at 1:200. Hum Pathol (2014) ncbi
mouse monoclonal (B-8)
  • immunocytochemistry; human
  • western blot; human
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz Biotechnology, sc-7966) was used in immunocytochemistry on human samples and in western blot on human samples . J Biol Chem (2014) ncbi
mouse monoclonal (B-8)
  • chromatin immunoprecipitation; human
  • immunoprecipitation; human
  • western blot; human
  • immunoprecipitation; mouse
  • western blot; mouse
Santa Cruz Biotechnology Smad4 antibody (Santa Cruz, sc-7966x) was used in chromatin immunoprecipitation on human samples , in immunoprecipitation on human samples , in western blot on human samples , in immunoprecipitation on mouse samples and in western blot on mouse samples . J Biol Chem (2013) ncbi
Abcam
domestic rabbit monoclonal (SP306)
  • western blot; human; loading ...; fig 3d
Abcam Smad4 antibody (Abcam, ab217267) was used in western blot on human samples (fig 3d). J Exp Clin Cancer Res (2021) ncbi
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry knockout validation; mouse; 1:1000; loading ...; fig 4c
  • western blot knockout validation; mouse; 1:500; loading ...; fig 4a
Abcam Smad4 antibody (Abcam, 40759) was used in immunohistochemistry knockout validation on mouse samples at 1:1000 (fig 4c) and in western blot knockout validation on mouse samples at 1:500 (fig 4a). Am J Physiol Gastrointest Liver Physiol (2021) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; human; 1:3000; loading ...; fig 3a
Abcam Smad4 antibody (Abcam, EP618Y) was used in western blot on human samples at 1:3000 (fig 3a). BMC Cancer (2019) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot knockout validation; mouse; loading ...; fig 2c
Abcam Smad4 antibody (Abcam, ab40759) was used in western blot knockout validation on mouse samples (fig 2c). J Biol Chem (2018) ncbi
domestic rabbit monoclonal (EP618Y)
  • chromatin immunoprecipitation; mouse; loading ...; fig 2g
Abcam Smad4 antibody (Abcam, EP618Y) was used in chromatin immunoprecipitation on mouse samples (fig 2g). Nature (2017) ncbi
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig s12e
Abcam Smad4 antibody (Abcam, AB40759) was used in immunohistochemistry - paraffin section on mouse samples (fig s12e). Nat Methods (2017) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; mouse; 1:2000; loading ...; fig 8d
In order to uncover the underlying molecular mechanism of radiation protection by MnTE-2-PyP in normal mouse prostate fibroblast cells, Abcam Smad4 antibody (Abcam, ab40759) was used in western blot on mouse samples at 1:2000 (fig 8d). Radiat Res (2017) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; human; 1:1000; loading ...; fig s5b
Abcam Smad4 antibody (Abcam, EP618Y) was used in western blot on human samples at 1:1000 (fig s5b). Gastroenterology (2016) ncbi
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry knockout validation; mouse; 1:100; fig 2d
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 2d
Abcam Smad4 antibody (Abcam, ab40759) was used in immunohistochemistry knockout validation on mouse samples at 1:100 (fig 2d) and in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 2d). Int J Biol Sci (2016) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; human; 1:2500; fig 5
In order to characterize the association with RASAL1 promoter hypermethylation in human coronary endothelial cells and hypoxia-induced endothelial-mesenchymal transition, Abcam Smad4 antibody (Abcam, Ab40759) was used in western blot on human samples at 1:2500 (fig 5). FEBS Lett (2016) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; human; fig s4
Abcam Smad4 antibody (Abcam, ab40759) was used in western blot on human samples (fig s4). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; fig 4
Abcam Smad4 antibody (abcam, ab110175) was used in immunocytochemistry on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EP618Y)
  • immunocytochemistry; rat; 1:100; fig 4
In order to examine the Act A signaling loop in a non-pathogenic state, Abcam Smad4 antibody (Abcam, ab40759) was used in immunocytochemistry on rat samples at 1:100 (fig 4). Neurochem Res (2016) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; mouse; fig 2
Abcam Smad4 antibody (Abcam, EP618Y) was used in western blot on mouse samples (fig 2). Cell (2015) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; human; fig 1
Abcam Smad4 antibody (Abcam, ab40759) was used in western blot on human samples (fig 1). World J Gastroenterol (2014) ncbi
domestic rabbit monoclonal (EP618Y)
  • immunohistochemistry - paraffin section; human; 1:100
Abcam Smad4 antibody (Abcam, ab40759) was used in immunohistochemistry - paraffin section on human samples at 1:100. Histopathology (2014) ncbi
domestic rabbit monoclonal (EP618Y)
  • western blot; mouse; 1:1000
In order to examine the functions of Smad proteins during cerebellum development, Abcam Smad4 antibody (Abcam, ab40759) was used in western blot on mouse samples at 1:1000. Mol Cell Biol (2013) ncbi
Invitrogen
mouse monoclonal (4G1C6)
  • immunohistochemistry - paraffin section; human; loading ...; fig s1
In order to report that SMAD4, FRAT1, and BCL2 are direct targets of miR-34a-3p and miR-34a-3p dysregulation modulates proliferation and apoptosis of meningioma cells, Invitrogen Smad4 antibody (Invitrogen, MA5-15682) was used in immunohistochemistry - paraffin section on human samples (fig s1). Aging (Albany NY) (2017) ncbi
Articles Reviewed
  1. Eritja N, Navaridas R, Ruiz Mitjana A, Vidal Sabanés M, Egea J, Encinas M, et al. Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation. Cancers (Basel). 2021;13: pubmed publisher
  2. Tan X, Tong L, Li L, Xu J, Xie S, Ji L, et al. Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation. Nat Commun. 2021;12:4853 pubmed publisher
  3. Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, et al. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression. J Exp Clin Cancer Res. 2021;40:214 pubmed publisher
  4. Niu B, Liu J, Lv B, Lin J, Li X, Wu C, et al. Interplay between transforming growth factor-β and Nur77 in dual regulations of inhibitor of differentiation 1 for colonic tumorigenesis. Nat Commun. 2021;12:2809 pubmed publisher
  5. Marincola Smith P, Choksi Y, Markham N, Hanna D, Zi J, Weaver C, et al. Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice. Am J Physiol Gastrointest Liver Physiol. 2021;320:G936-G957 pubmed publisher
  6. Gori I, George R, Purkiss A, Strohbuecker S, Randall R, Ogrodowicz R, et al. Mutations in SKI in Shprintzen-Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization. elife. 2021;10: pubmed publisher
  7. Beel S, Kolloch L, Apken L, Jürgens L, Bolle A, Sudhof N, et al. κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis. Nat Commun. 2020;11:3409 pubmed publisher
  8. Gibbs Z, Reza L, Cheng C, Westcott J, McGlynn K, Whitehurst A. The testis protein ZNF165 is a SMAD3 cofactor that coordinates oncogenic TGFβ signaling in triple-negative breast cancer. elife. 2020;9: pubmed publisher
  9. Wang Z, Li Y, Zhan S, Zhang L, Zhang S, Tang Q, et al. SMAD4 Y353C promotes the progression of PDAC. BMC Cancer. 2019;19:1037 pubmed publisher
  10. Matsumoto S, Yamamichi T, Shinzawa K, Kasahara Y, Nojima S, Kodama T, et al. GREB1 induced by Wnt signaling promotes development of hepatoblastoma by suppressing TGFβ signaling. Nat Commun. 2019;10:3882 pubmed publisher
  11. Jin H, Xue L, Mo L, Zhang D, Guo X, Xu J, et al. Downregulation of miR-200c stabilizes XIAP mRNA and contributes to invasion and lung metastasis of bladder cancer. Cell Adh Migr. 2019;13:236-248 pubmed publisher
  12. Tsai C, Tsai C, Yi J, Kao H, Huang Y, Wang C, et al. Activin A regulates the epidermal growth factor receptor promoter by activating the PI3K/SP1 pathway in oral squamous cell carcinoma cells. Sci Rep. 2019;9:5197 pubmed publisher
  13. Biffi G, Oni T, Spielman B, Hao Y, Elyada E, Park Y, et al. IL1-Induced JAK/STAT Signaling Is Antagonized by TGFβ to Shape CAF Heterogeneity in Pancreatic Ductal Adenocarcinoma. Cancer Discov. 2019;9:282-301 pubmed publisher
  14. Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed publisher
  15. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  16. Bajikar S, Wang C, Borten M, Pereira E, Atkins K, Janes K. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer. Dev Cell. 2017;43:418-435.e13 pubmed publisher
  17. Zhang S, Takaku M, Zou L, Gu A, Chou W, Zhang G, et al. Reversing SKI-SMAD4-mediated suppression is essential for TH17 cell differentiation. Nature. 2017;551:105-109 pubmed publisher
  18. Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, et al. miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017;7:4002 pubmed publisher
  19. Rogers Z, McFarland C, Winters I, Naranjo S, Chuang C, Petrov D, et al. A quantitative and multiplexed approach to uncover the fitness landscape of tumor suppression in vivo. Nat Methods. 2017;14:737-742 pubmed publisher
  20. Wassermann Dozorets R, Rubinstein M. C/EBPβ LIP augments cell death by inducing osteoglycin. Cell Death Dis. 2017;8:e2733 pubmed publisher
  21. Werner T, Hart M, Nickels R, Kim Y, Menger M, Bohle R, et al. MiR-34a-3p alters proliferation and apoptosis of meningioma cells in vitro and is directly targeting SMAD4, FRAT1 and BCL2. Aging (Albany NY). 2017;9:932-954 pubmed publisher
  22. Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
  23. Fumagalli A, Drost J, Suijkerbuijk S, van Boxtel R, de Ligt J, Offerhaus G, et al. Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proc Natl Acad Sci U S A. 2017;114:E2357-E2364 pubmed publisher
  24. Chatterjee A, Kosmacek E, Oberley Deegan R. MnTE-2-PyP Treatment, or NOX4 Inhibition, Protects against Radiation-Induced Damage in Mouse Primary Prostate Fibroblasts by Inhibiting the TGF-Beta 1 Signaling Pathway. Radiat Res. 2017;187:367-381 pubmed publisher
  25. Whitaker A, Berthet E, Cantu A, Laird D, Alliston T. Smad4 regulates growth plate matrix production and chondrocyte polarity. Biol Open. 2017;6:358-364 pubmed publisher
  26. . Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed publisher
  27. Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher
  28. Lyroni K, Patsalos A, Daskalaki M, Doxaki C, Soennichsen B, Helms M, et al. Epigenetic and Transcriptional Regulation of IRAK-M Expression in Macrophages. J Immunol. 2017;198:1297-1307 pubmed publisher
  29. Kocsis T, Trencsenyi G, Szabó K, Baán J, Müller G, Mendler L, et al. Myostatin propeptide mutation of the hypermuscular Compact mice decreases the formation of myostatin and improves insulin sensitivity. Am J Physiol Endocrinol Metab. 2017;312:E150-E160 pubmed publisher
  30. Paris N, Soroka A, Klose A, Liu W, Chakkalakal J. Smad4 restricts differentiation to promote expansion of satellite cell derived progenitors during skeletal muscle regeneration. elife. 2016;5: pubmed publisher
  31. Chan D, Hui W, Wang J, Yung M, Hui L, Qin Y, et al. DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling. Oncogene. 2017;36:1404-1416 pubmed publisher
  32. Yamaguchi J, Mino Kenudson M, Liss A, Chowdhury S, Wang T, Fernández Del Castillo C, et al. Loss of Trefoil Factor 2 From Pancreatic Duct Glands Promotes Formation of Intraductal Papillary Mucinous Neoplasms in Mice. Gastroenterology. 2016;151:1232-1244.e10 pubmed publisher
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