This is a Validated Antibody Database (VAD) review about mouse Siglec H, based on 28 published articles (read how Labome selects the articles), using Siglec H antibody in all methods. It is aimed to help Labome visitors find the most suited Siglec H antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Siglec H synonym: 6430529G09Rik; Siglec-H

BioLegend
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig e2b
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig e2b). Nature (2022) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; 1:500; loading ...; fig 6a, s2a, s2c
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples at 1:500 (fig 6a, s2a, s2c). Immunol Cell Biol (2022) ncbi
rat monoclonal (551)
  • flow cytometry; mouse
BioLegend Siglec H antibody (BioLegend, 129605) was used in flow cytometry on mouse samples . J Clin Invest (2020) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 2c
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig 2c). J Virol (2020) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 2d, s3a, s3b, s7c
BioLegend Siglec H antibody (Biolegend, 129605) was used in flow cytometry on mouse samples (fig 2d, s3a, s3b, s7c). Cell Rep (2019) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 5f
BioLegend Siglec H antibody (BioLegend, 129606) was used in flow cytometry on mouse samples (fig 5f). Cell (2019) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 1c
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig 1c). J Immunol (2019) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 6a
BioLegend Siglec H antibody (Biolegend, 551) was used in flow cytometry on mouse samples (fig 6a). Front Immunol (2018) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; fig 1a
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig 1a). Eur J Immunol (2017) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; loading ...; fig 1d
In order to show that Bhlhe40 expression marks encephalitogenic T helper cells and that the PTX-IL-1-Bhlhe40 pathway is active in mice with experimental autoimmune encephalomyelitis, BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig 1d). J Exp Med (2016) ncbi
rat monoclonal (551)
  • flow cytometry; mouse; fig s1
BioLegend Siglec H antibody (BioLegend, 551) was used in flow cytometry on mouse samples (fig s1). J Leukoc Biol (2015) ncbi
Invitrogen
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig 1d
Invitrogen Siglec H antibody (eBioscience, 12-0333-82) was used in flow cytometry on mouse samples (fig 1d). Immunity (2019) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig s1
Invitrogen Siglec H antibody (eBioscience, ebio440c) was used in flow cytometry on mouse samples (fig s1). Front Immunol (2018) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig 1d
Invitrogen Siglec H antibody (eBiosciences, eBio44c) was used in flow cytometry on mouse samples (fig 1d). J Clin Invest (2018) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig 2k
In order to investigate the role of type I interferons in diet-induced obesity and insulin resistance, Invitrogen Siglec H antibody (eBioscience, 440c) was used in flow cytometry on mouse samples (fig 2k). Diabetologia (2017) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; fig 1b
In order to explore how the different Fcgamma receptors expressed on dendritic cells affect the initiation of T cell responses, Invitrogen Siglec H antibody (ebioscience, eBio440C) was used in flow cytometry on mouse samples (fig 1b). J Exp Med (2017) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig 1b
In order to find a role for RAB43 in cross-presentation by classical dendritic cells, Invitrogen Siglec H antibody (eBiosciences, eBio440c) was used in flow cytometry on mouse samples (fig 1b). J Exp Med (2016) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig 5a
In order to describe an algorithm for constructing cell lineages from single-cell data, Invitrogen Siglec H antibody (eBioscience, 440c) was used in flow cytometry on mouse samples (fig 5a). Nat Commun (2016) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; loading ...; fig s3a
In order to explore the relationship between sphingosine 1-phosphate receptor 1 and interferon alpha receptor 1 signaling, Invitrogen Siglec H antibody (eBioscience, eBio440c) was used in flow cytometry on mouse samples (fig s3a). Proc Natl Acad Sci U S A (2016) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse
In order to show how early events during viral infection decide the immune response and facilitate either control, clearance, or persistence of the virus, Invitrogen Siglec H antibody (eBioscience, 440C) was used in flow cytometry on mouse samples . PLoS Pathog (2015) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse
In order to test if professional antigen-presenting cell subsets and MCMV-encoded evasins alter IFN-I responses, Invitrogen Siglec H antibody (eBioscience, eBio440c) was used in flow cytometry on mouse samples . J Virol (2014) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse
In order to identify CD11b(+) classical dendritic cells as the source of IL-23 in C. rodentium infected mice, Invitrogen Siglec H antibody (eBioscience, eBio440C) was used in flow cytometry on mouse samples . Nat Immunol (2013) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; fig 6b
In order to report the development of dendritic cells and other lineages in Bcl11a knockout mice, Invitrogen Siglec H antibody (eBioscience, eBio440C) was used in flow cytometry on mouse samples (fig 6b). PLoS ONE (2013) ncbi
rat monoclonal (eBio440c)
  • flow cytometry; mouse; fig 7
In order to test if upregulation of major histocompatibility complex class II and costimulatory molecules in the retina contributes to the regulation of CD4 T cells, Invitrogen Siglec H antibody (eBioscience, eBIO440C) was used in flow cytometry on mouse samples (fig 7). Infect Immun (2010) ncbi
Miltenyi Biotec
rat monoclonal (551.3D3)
  • flow cytometry; mouse; fig s1a
In order to investigate the impact of Siglec-H on type I IFN responses and virus infection, Miltenyi Biotec Siglec H antibody (Miltenyi Biotec, 551.3D3) was used in flow cytometry on mouse samples (fig s1a). J Exp Med (2016) ncbi
Bio X Cell
rat monoclonal (440c)
  • blocking or activating experiments; mouse; fig 6a
Bio X Cell Siglec H antibody (Bio X Cell, 440c) was used in blocking or activating experiments on mouse samples (fig 6a). Mucosal Immunol (2016) ncbi
Abcam
rat monoclonal (440c)
  • flow cytometry; mouse; 1:50; loading ...; fig 1c
Abcam Siglec H antibody (Abcam, 440C) was used in flow cytometry on mouse samples at 1:50 (fig 1c). elife (2018) ncbi
BD Biosciences
rat monoclonal (440c)
  • flow cytometry; mouse; loading ...; fig 6c
BD Biosciences Siglec H antibody (BD, 440c) was used in flow cytometry on mouse samples (fig 6c). Front Immunol (2019) ncbi
Articles Reviewed
  1. Brown G, Ca xf1 ete P, Wang H, Medhavy A, Bones J, Roco J, et al. TLR7 gain-of-function genetic variation causes human lupus. Nature. 2022;605:349-356 pubmed publisher
  2. Clayer E, Frank D, Anderton H, Zhang S, Kueh A, Heim V, et al. ZC3H12C expression in dendritic cells is necessary to prevent lymphadenopathy of skin-draining lymph nodes. Immunol Cell Biol. 2022;100:160-173 pubmed publisher
  3. Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher
  4. Forbester J, Clement M, Wellington D, Yeung A, Dimonte S, Marsden M, et al. IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models. J Virol. 2020;94: pubmed publisher
  5. Bell O, Copland D, Ward A, Nicholson L, Lange C, Chu C, et al. Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation. Front Immunol. 2019;10:3033 pubmed publisher
  6. Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed publisher
  7. Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
  8. McLaren J, Clement M, Marsden M, Miners K, Llewellyn Lacey S, Grant E, et al. IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine. J Immunol. 2019;202:943-955 pubmed publisher
  9. Chopin M, Lun A, Zhan Y, Schreuder J, Coughlan H, D Amico A, et al. Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT. Immunity. 2019;50:77-90.e5 pubmed publisher
  10. Hayashi T, Momota M, Kuroda E, Kusakabe T, Kobari S, Makisaka K, et al. DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination. Front Immunol. 2018;9:2619 pubmed publisher
  11. Ko Y, Chan Y, Liu C, Liang J, Chuang T, Hsueh Y, et al. Blimp-1-Mediated Pathway Promotes Type I IFN Production in Plasmacytoid Dendritic Cells by Targeting to Interleukin-1 Receptor-Associated Kinase M. Front Immunol. 2018;9:1828 pubmed publisher
  12. Webster B, Werneke S, Zafirova B, This S, Coléon S, Decembre E, et al. Plasmacytoid dendritic cells control dengue and Chikungunya virus infections via IRF7-regulated interferon responses. elife. 2018;7: pubmed publisher
  13. Panda S, Facchinetti V, Voynova E, Hanabuchi S, Karnell J, Hanna R, et al. Galectin-9 inhibits TLR7-mediated autoimmunity in murine lupus models. J Clin Invest. 2018;128:1873-1887 pubmed publisher
  14. Hannibal T, Schmidt Christensen A, Nilsson J, Fransén Pettersson N, Hansen L, Holmberg D. Deficiency in plasmacytoid dendritic cells and type I interferon signalling prevents diet-induced obesity and insulin resistance in mice. Diabetologia. 2017;60:2033-2041 pubmed publisher
  15. Anderson D, Grajales Reyes G, Satpathy A, Vasquez Hueichucura C, Murphy T, Murphy K. Revisiting the specificity of the MHC class?II transactivator CIITA in classical murine dendritic cells in vivo. Eur J Immunol. 2017;47:1317-1323 pubmed publisher
  16. Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed publisher
  17. Kretzer N, Theisen D, Tussiwand R, Briseño C, Grajales Reyes G, Wu X, et al. RAB43 facilitates cross-presentation of cell-associated antigens by CD8?+ dendritic cells. J Exp Med. 2016;213:2871-2883 pubmed
  18. Schmitt H, Sell S, Koch J, Seefried M, Sonnewald S, Daniel C, et al. Siglec-H protects from virus-triggered severe systemic autoimmunity. J Exp Med. 2016;213:1627-44 pubmed publisher
  19. Chen J, Schlitzer A, Chakarov S, Ginhoux F, Poidinger M. Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development. Nat Commun. 2016;7:11988 pubmed publisher
  20. Lin C, Bradstreet T, Schwarzkopf E, Jarjour N, Chou C, Archambault A, et al. IL-1-induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation. J Exp Med. 2016;213:251-71 pubmed publisher
  21. Teijaro J, Studer S, Leaf N, Kiosses W, Nguyen N, Matsuki K, et al. S1PR1-mediated IFNAR1 degradation modulates plasmacytoid dendritic cell interferon-α autoamplification. Proc Natl Acad Sci U S A. 2016;113:1351-6 pubmed publisher
  22. Wu V, Smith A, You H, Nguyen T, Ferguson R, Taylor M, et al. Plasmacytoid dendritic cell-derived IFNα modulates Th17 differentiation during early Bordetella pertussis infection in mice. Mucosal Immunol. 2016;9:777-86 pubmed publisher
  23. Sullivan B, Teijaro J, de la Torre J, Oldstone M. Early virus-host interactions dictate the course of a persistent infection. PLoS Pathog. 2015;11:e1004588 pubmed publisher
  24. Evrard M, Chong S, Devi S, Chew W, Lee B, Poidinger M, et al. Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy. J Leukoc Biol. 2015;97:611-9 pubmed publisher
  25. Döring M, Lessin I, Frenz T, Spanier J, Kessler A, Tegtmeyer P, et al. M27 expressed by cytomegalovirus counteracts effective type I interferon induction of myeloid cells but not of plasmacytoid dendritic cells. J Virol. 2014;88:13638-50 pubmed publisher
  26. Satpathy A, Briseño C, Lee J, Ng D, Manieri N, Kc W, et al. Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens. Nat Immunol. 2013;14:937-48 pubmed publisher
  27. Wu X, Satpathy A, Kc W, Liu P, Murphy T, Murphy K. Bcl11a controls Flt3 expression in early hematopoietic progenitors and is required for pDC development in vivo. PLoS ONE. 2013;8:e64800 pubmed publisher
  28. Charles E, Joshi S, Ash J, Fox B, Farris A, Bzik D, et al. CD4 T-cell suppression by cells from Toxoplasma gondii-infected retinas is mediated by surface protein PD-L1. Infect Immun. 2010;78:3484-92 pubmed publisher