This is a Validated Antibody Database (VAD) review about mouse Scn10a, based on 13 published articles (read how Labome selects the articles), using Scn10a antibody in all methods. It is aimed to help Labome visitors find the most suited Scn10a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Scn10a synonym: Nav1.8; PN3; SNS; sodium channel protein type 10 subunit alpha; peripheral nerve sodium channel 3; sensory neuron sodium channel; sodium channel protein type X subunit alpha; voltage gated sodium channel; voltage-gated sodium channel Nav1.8 variant a; voltage-gated sodium channel Nav1.8 variant b; voltage-gated sodium channel subunit alpha Nav1.8

Sigma-Aldrich
mouse monoclonal (K58/35)
  • western blot; rat; 1:200; loading ...; fig 8
In order to demonstrate that fibroblast growth factor 14 affects KCNQ channel function and localization, Sigma-Aldrich Scn10a antibody (Sigma, K58/35) was used in western blot on rat samples at 1:200 (fig 8). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (K58/35)
  • immunohistochemistry - frozen section; mouse; 1:250; loading ...; fig 4d
In order to examine the role of Opalin in mammalian myelination, Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in immunohistochemistry - frozen section on mouse samples at 1:250 (fig 4d). PLoS ONE (2016) ncbi
mouse monoclonal (K58/35)
  • western blot; mouse; fig 1
Sigma-Aldrich Scn10a antibody (Sigma Aldrich, K58/35) was used in western blot on mouse samples (fig 1). Nat Commun (2016) ncbi
mouse monoclonal (K58/35)
  • immunohistochemistry - frozen section; rat; 1:100; loading ...; fig 2a
Sigma-Aldrich Scn10a antibody (Sigma-Aldrich, S8809) was used in immunohistochemistry - frozen section on rat samples at 1:100 (fig 2a). J Comp Neurol (2017) ncbi
mouse monoclonal (K58/35)
  • immunohistochemistry - frozen section; mouse; 1:200; loading ...; fig 5a
  • immunoprecipitation; mouse; 1:200; loading ...; fig 4a
Sigma-Aldrich Scn10a antibody (Sigma-Aldrich, S8809) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 5a) and in immunoprecipitation on mouse samples at 1:200 (fig 4a). J Neurosci (2016) ncbi
mouse monoclonal (K58/35)
  • immunohistochemistry - frozen section; mouse; 1:300; fig s7
Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in immunohistochemistry - frozen section on mouse samples at 1:300 (fig s7). Front Cell Neurosci (2016) ncbi
mouse monoclonal (K58/35)
  • immunoprecipitation; mouse; fig 6
  • western blot; mouse; 1:1000; fig 1
In order to study native cerebellar iFGF14 complexes by proteomic analysis, Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in immunoprecipitation on mouse samples (fig 6) and in western blot on mouse samples at 1:1000 (fig 1). Channels (Austin) (2016) ncbi
mouse monoclonal (K58/35)
  • western blot; Domestic guinea pig; 1:800; fig 6
Sigma-Aldrich Scn10a antibody (Sigma-Aldrich, S8809) was used in western blot on Domestic guinea pig samples at 1:800 (fig 6). PLoS ONE (2016) ncbi
mouse monoclonal (K58/35)
  • western blot; mouse
In order to examine the effects of Kidins220 ablation on neuronal excitability, Sigma-Aldrich Scn10a antibody (Sigma Aldrich, S8809) was used in western blot on mouse samples . J Biol Chem (2015) ncbi
mouse monoclonal (K58/35)
  • western blot; human; fig s6
Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in western blot on human samples (fig s6). PLoS ONE (2015) ncbi
mouse monoclonal (K58/35)
  • immunocytochemistry; rat; loading ...; fig 2e
Sigma-Aldrich Scn10a antibody (Sigma-Aldrich, S8809) was used in immunocytochemistry on rat samples (fig 2e). J Cell Biol (2015) ncbi
mouse monoclonal (K58/35)
  • immunocytochemistry; rat; 1:100; fig 6
Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in immunocytochemistry on rat samples at 1:100 (fig 6). J Neurosci (2015) ncbi
mouse monoclonal (K58/35)
  • immunohistochemistry; mouse; 1:100
In order to use multicolor labeling technology to simultaneously individual oligodendrocytes in the postnatal mouse optic nerve, Sigma-Aldrich Scn10a antibody (Sigma, S8809) was used in immunohistochemistry on mouse samples at 1:100. Glia (2015) ncbi
Articles Reviewed
  1. Pablo J, Pitt G. FGF14 is a regulator of KCNQ2/3 channels. Proc Natl Acad Sci U S A. 2017;114:154-159 pubmed publisher
  2. Yoshikawa F, Sato Y, Tohyama K, Akagi T, Furuse T, Sadakata T, et al. Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments. PLoS ONE. 2016;11:e0166732 pubmed publisher
  3. Dover K, Marra C, Solinas S, Popovic M, Subramaniyam S, Zecevic D, et al. FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon. Nat Commun. 2016;7:12895 pubmed publisher
  4. Serwanski D, Jukkola P, Nishiyama A. Heterogeneity of astrocyte and NG2 cell insertion at the node of ranvier. J Comp Neurol. 2017;525:535-552 pubmed publisher
  5. Kruger L, O Malley H, Hull J, Kleeman A, Patino G, Isom L. ?1-C121W Is Down But Not Out: Epilepsy-Associated Scn1b-C121W Results in a Deleterious Gain-of-Function. J Neurosci. 2016;36:6213-24 pubmed publisher
  6. Alshammari M, Alshammari T, Laezza F. Improved Methods for Fluorescence Microscopy Detection of Macromolecules at the Axon Initial Segment. Front Cell Neurosci. 2016;10:5 pubmed publisher
  7. Bosch M, Nerbonne J, Townsend R, Miyazaki H, Nukina N, Ornitz D, et al. Proteomic analysis of native cerebellar iFGF14 complexes. Channels (Austin). 2016;10:297-312 pubmed publisher
  8. Nassal D, Wan X, Liu H, Deschênes I. Myocardial KChIP2 Expression in Guinea Pig Resolves an Expanded Electrophysiologic Role. PLoS ONE. 2016;11:e0146561 pubmed publisher
  9. Cesca F, Satapathy A, Ferrea E, Nieus T, Benfenati F, Scholz Starke J. Functional Interaction between the Scaffold Protein Kidins220/ARMS and Neuronal Voltage-Gated Na+ Channels. J Biol Chem. 2015;290:18045-55 pubmed publisher
  10. Koenig J, Werdehausen R, Linley J, Habib A, Vernon J, Lolignier S, et al. Regulation of Nav1.7: A Conserved SCN9A Natural Antisense Transcript Expressed in Dorsal Root Ganglia. PLoS ONE. 2015;10:e0128830 pubmed publisher
  11. Colombelli C, Palmisano M, Eshed Eisenbach Y, Zambroni D, Pavoni E, Ferri C, et al. Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin. J Cell Biol. 2015;208:313-29 pubmed publisher
  12. Chand A, Galliano E, Chesters R, Grubb M. A distinct subtype of dopaminergic interneuron displays inverted structural plasticity at the axon initial segment. J Neurosci. 2015;35:1573-90 pubmed publisher
  13. Dumas L, Heitz Marchaland C, Fouquet S, Suter U, Livet J, Moreau Fauvarque C, et al. Multicolor analysis of oligodendrocyte morphology, interactions, and development with Brainbow. Glia. 2015;63:699-717 pubmed publisher