This is a Validated Antibody Database (VAD) review about mouse Scgn, based on 7 published articles (read how Labome selects the articles), using Scgn antibody in all methods. It is aimed to help Labome visitors find the most suited Scgn antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Knockout validation
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • immunocytochemistry knockout validation; mouse; 1:50; loading ...; fig 3c
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3s1
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2c, 2e, 2f
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 2a
Santa Cruz Biotechnology Scgn antibody (Santa Cruz, sc-374355) was used in immunocytochemistry knockout validation on mouse samples at 1:50 (fig 3c), in western blot knockout validation on mouse samples at 1:1000 (fig 3s1), in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2c, 2e, 2f) and in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2a). elife (2019) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-9)
  • immunocytochemistry; mouse; 1:100; loading ...; fig 1b
  • western blot; mouse; 1:400; loading ...; fig 1a
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 2b
  • immunocytochemistry; human; 1:100; loading ...; fig 1b
  • western blot; human; 1:400; loading ...; fig 1a
Santa Cruz Biotechnology Scgn antibody (Santa Cruz, sc-374355) was used in immunocytochemistry on mouse samples at 1:100 (fig 1b), in western blot on mouse samples at 1:400 (fig 1a), in immunohistochemistry - paraffin section on human samples at 1:100 (fig 2b), in immunocytochemistry on human samples at 1:100 (fig 1b) and in western blot on human samples at 1:400 (fig 1a). Oncol Lett (2020) ncbi
mouse monoclonal (F-9)
  • immunocytochemistry knockout validation; mouse; 1:50; loading ...; fig 3c
  • western blot knockout validation; mouse; 1:1000; loading ...; fig 3s1
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 2c, 2e, 2f
  • immunohistochemistry - paraffin section; human; 1:50; loading ...; fig 2a
Santa Cruz Biotechnology Scgn antibody (Santa Cruz, sc-374355) was used in immunocytochemistry knockout validation on mouse samples at 1:50 (fig 3c), in western blot knockout validation on mouse samples at 1:1000 (fig 3s1), in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 2c, 2e, 2f) and in immunohistochemistry - paraffin section on human samples at 1:50 (fig 2a). elife (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (C26D12)
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig s6b
Cell Signaling Technology Scgn antibody (CST, 2173) was used in immunohistochemistry - paraffin section on mouse samples at 1:400 (fig s6b). Nat Commun (2019) ncbi
domestic rabbit monoclonal (C26D12)
  • immunohistochemistry - free floating section; mouse; loading ...; fig 5b
Cell Signaling Technology Scgn antibody (Cell Signaling, 2173) was used in immunohistochemistry - free floating section on mouse samples (fig 5b). Sci Transl Med (2018) ncbi
domestic rabbit monoclonal (C26D12)
  • immunohistochemistry - frozen section; mouse; 1:500
Cell Signaling Technology Scgn antibody (Cell Signaling, 2173) was used in immunohistochemistry - frozen section on mouse samples at 1:500. Brain Struct Funct (2015) ncbi
BioVendor-Laboratorni medicina a.s. CTPark Modrice
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig s5a
BioVendor-Laboratorni medicina a.s. CTPark Modrice Scgn antibody (BioVendor, RD181120100) was used in immunohistochemistry - frozen section on mouse samples (fig s5a). Cell Rep (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:1000; fig 2
In order to analyze the reduction of amplitudes in electroretinograms and altered sphinogolipid composition in retina and cornea by defective ceramide synthases in mice, BioVendor-Laboratorni medicina a.s. CTPark Modrice Scgn antibody (BioVendor, RD181120100) was used in immunohistochemistry - frozen section on mouse samples at 1:1000 (fig 2). Eur J Neurosci (2016) ncbi
Articles Reviewed
  1. Burger C, Albrecht N, Jiang D, Liang J, Poch xe9 R, Samuel M. LKB1 and AMPK instruct cone nuclear position to modify visual function. Cell Rep. 2021;34:108698 pubmed publisher
  2. Dong Y, Li Y, Liu R, Li Y, Zhang H, Liu H, et al. Secretagogin, a marker for neuroendocrine cells, is more sensitive and specific in large cell neuroendocrine carcinoma compared with the markers CD56, CgA, Syn and Napsin A. Oncol Lett. 2020;19:2223-2230 pubmed publisher
  3. Ocasio J, Babcock B, Malawsky D, Weir S, Loo L, Simon J, et al. scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy. Nat Commun. 2019;10:5829 pubmed publisher
  4. Sifuentes Dominguez L, Li H, Llano E, Liu Z, Singla A, Patel A, et al. SCGN deficiency results in colitis susceptibility. elife. 2019;8: pubmed publisher
  5. Ou Yang M, Kurz J, Nomura T, Popovic J, Rajapaksha T, Dong H, et al. Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Sci Transl Med. 2018;10: pubmed publisher
  6. Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed publisher
  7. Kao F, Su S, Carlson G, Liao W. MeCP2-mediated alterations of striatal features accompany psychomotor deficits in a mouse model of Rett syndrome. Brain Struct Funct. 2015;220:419-34 pubmed publisher