This is a Validated Antibody Database (VAD) review about mouse Runx2, based on 84 published articles (read how Labome selects the articles), using Runx2 antibody in all methods. It is aimed to help Labome visitors find the most suited Runx2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Runx2 synonym: AML3; Cbf; Cbfa-1; Cbfa1; LS3; Osf2; PEBP2aA; Pebp2a1; Pebpa2a

Knockout validation
MBL International
monoclonal (8G5)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 3a
MBL International Runx2 antibody (MBL, D130-3) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 3a). J Cell Physiol (2019) ncbi
Abcam
mouse monoclonal
  • western blot; mouse; loading ...; fig 2d
  • EMSA; African green monkey; loading ...; fig 6h
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on mouse samples (fig 2d) and in EMSA on African green monkey samples (fig 6h). Cell Rep (2022) ncbi
domestic rabbit monoclonal (EPR3099)
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 1i
Abcam Runx2 antibody (Abcam, ab92336) was used in immunohistochemistry - paraffin section on mouse samples (fig 1i). Cell Rep (2021) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig s5c
Abcam Runx2 antibody (Abcam, ab76956) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig s5c). Bone Res (2021) ncbi
mouse monoclonal
  • western blot; mouse; loading ...; fig 4h
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on mouse samples (fig 4h). Mol Cells (2021) ncbi
mouse monoclonal
  • western blot; mouse; loading ...; fig 6a
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on mouse samples (fig 6a). Front Pharmacol (2021) ncbi
domestic rabbit monoclonal (EPR22858-106)
  • western blot; rat; 1:1000; loading ...; fig 2e
Abcam Runx2 antibody (Abcam, ab236639) was used in western blot on rat samples at 1:1000 (fig 2e). Aging (Albany NY) (2021) ncbi
mouse monoclonal
  • western blot; mouse; 1:1000; loading ...; fig 9b
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on mouse samples at 1:1000 (fig 9b). Int J Mol Med (2021) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3i
Abcam Runx2 antibody (Abcam, ab76956) was used in immunohistochemistry - paraffin section on mouse samples (fig 3i). Biomed Res Int (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4e
Abcam Runx2 antibody (Abcam, ab23981) was used in western blot on mouse samples (fig 4e). Cell Prolif (2021) ncbi
domestic rabbit monoclonal (EPR14334)
  • immunohistochemistry; mouse; 1:1000; loading ...; fig 6a
Abcam Runx2 antibody (Abcam, ab192256) was used in immunohistochemistry on mouse samples at 1:1000 (fig 6a). Genes Dev (2021) ncbi
domestic rabbit monoclonal (EPR14334)
  • immunohistochemistry; human; 1:1000; loading ...; fig s3e
Abcam Runx2 antibody (abcam, ab192256) was used in immunohistochemistry on human samples at 1:1000 (fig s3e). Genome Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Abcam Runx2 antibody (Abcam, Ab23981) was used in western blot on human samples (fig 4d). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4b
Abcam Runx2 antibody (Abcam, 23981) was used in western blot on mouse samples (fig 4b). Bioact Mater (2021) ncbi
domestic rabbit monoclonal (EPR14334)
  • immunohistochemistry - paraffin section; human; 1:200; fig 9
Abcam Runx2 antibody (Abcam, ab192256) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 9). Cells (2020) ncbi
mouse monoclonal
  • western blot; mouse; 1:2000; fig 4b
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on mouse samples at 1:2000 (fig 4b). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; mouse; loading ...; fig 3c
  • western blot; mouse; loading ...; fig 4c
Abcam Runx2 antibody (Abcam, ab23981) was used in immunohistochemistry on mouse samples (fig 3c) and in western blot on mouse samples (fig 4c). Int J Mol Sci (2020) ncbi
mouse monoclonal
  • western blot; human; loading ...; fig 6a
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples (fig 6a). Sci Rep (2020) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 2a
Abcam Runx2 antibody (Abcam, ab23981) was used in western blot on human samples at 1:1000 (fig 2a). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (EPR14334)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 4c
Abcam Runx2 antibody (Abcam, EPR14334) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 4c). Nat Commun (2019) ncbi
domestic rabbit monoclonal (EPR3099)
  • immunocytochemistry; human; loading ...; fig 3d
Abcam Runx2 antibody (abcam, ab92336) was used in immunocytochemistry on human samples (fig 3d). Cell (2019) ncbi
domestic rabbit monoclonal (EPR3099)
  • western blot; human; loading ...; fig 1d
Abcam Runx2 antibody (Abcam, ab92336) was used in western blot on human samples (fig 1d). Leukemia (2019) ncbi
mouse monoclonal
  • western blot; human; 1:1000; loading ...; fig 5c
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples at 1:1000 (fig 5c). Aging (Albany NY) (2019) ncbi
domestic rabbit monoclonal (EPR14334)
  • flow cytometry; mouse; 1:50; loading ...; fig s3a
Abcam Runx2 antibody (Abcam, ab192256) was used in flow cytometry on mouse samples at 1:50 (fig s3a). Bone Res (2018) ncbi
domestic rabbit monoclonal (EPR3099)
  • western blot; human; 1:1000; loading ...; fig 2a
Abcam Runx2 antibody (Abcam, 92336) was used in western blot on human samples at 1:1000 (fig 2a). Cell Rep (2018) ncbi
domestic rabbit monoclonal (EPR3099)
  • western blot; mouse; 1:500; loading ...; fig 5e
Abcam Runx2 antibody (Abcam, AB92336) was used in western blot on mouse samples at 1:500 (fig 5e). Mol Cell Biol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3e
Abcam Runx2 antibody (Abcam, ab23981) was used in western blot on human samples at 1:1000 (fig 3e). Biomed Res Int (2018) ncbi
mouse monoclonal
  • western blot; human; 1:10,000; loading ...; fig 4b
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples at 1:10,000 (fig 4b). Biosci Rep (2018) ncbi
domestic rabbit monoclonal (EPR3099)
  • western blot; mouse; loading ...; fig 2b
Abcam Runx2 antibody (Abcam, ab92336) was used in western blot on mouse samples (fig 2b). elife (2018) ncbi
domestic rabbit monoclonal (EPR3099)
  • western blot; mouse; loading ...; fig 5a
Abcam Runx2 antibody (Abcam, ab92336) was used in western blot on mouse samples (fig 5a). BMC Musculoskelet Disord (2017) ncbi
domestic rabbit monoclonal (EPR3099)
  • immunohistochemistry; mouse; loading ...; fig 2b
Abcam Runx2 antibody (Abcam, ab92336) was used in immunohistochemistry on mouse samples (fig 2b). Nat Commun (2017) ncbi
domestic rabbit monoclonal (EPR3099)
  • flow cytometry; mouse; loading ...; fig 3e
In order to show erythro-myeloid progenitors directly differentiate into endothelial cells, Abcam Runx2 antibody (Abcam, ab92336) was used in flow cytometry on mouse samples (fig 3e). Sci Rep (2017) ncbi
mouse monoclonal
  • western blot; human; fig 3a
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples (fig 3a). Int J Mol Med (2016) ncbi
mouse monoclonal
  • western blot; human; 1:500; fig 4
In order to study the role of kif3a in dental mesenchymal stem and precursor cell differentiation, Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples at 1:500 (fig 4). Mol Med Rep (2016) ncbi
domestic rabbit monoclonal (EPR3099)
  • immunohistochemistry; mouse; 1:200; loading ...; fig 7e
In order to report that neogenin signaling controls the balance of neurons and glial cells produced in the olfactory epithelium, Abcam Runx2 antibody (Abcam, ab92336) was used in immunohistochemistry on mouse samples at 1:200 (fig 7e). Development (2016) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:200; fig s4
  • western blot; mouse; 1:1000; fig 5
Abcam Runx2 antibody (abcam, ab23981) was used in immunohistochemistry - paraffin section on mouse samples at 1:200 (fig s4) and in western blot on mouse samples at 1:1000 (fig 5). Nat Commun (2016) ncbi
mouse monoclonal
  • western blot; human; 1:1000; fig 6
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples at 1:1000 (fig 6). Cancer Med (2015) ncbi
domestic rabbit monoclonal (EPR3099)
  • immunohistochemistry; mouse; fig 4a
Abcam Runx2 antibody (Abcam, 92336) was used in immunohistochemistry on mouse samples (fig 4a). Proc Natl Acad Sci U S A (2015) ncbi
mouse monoclonal
  • immunocytochemistry; human; 1:200; fig 4b
Abcam Runx2 antibody (Abcam, ab76956) was used in immunocytochemistry on human samples at 1:200 (fig 4b). Stem Cell Res Ther (2015) ncbi
domestic rabbit monoclonal (EPR3099)
  • chromatin immunoprecipitation; mouse; fig 6
  • western blot; mouse; fig 6
Abcam Runx2 antibody (Abcam, ab92336) was used in chromatin immunoprecipitation on mouse samples (fig 6) and in western blot on mouse samples (fig 6). elife (2014) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:1000
Abcam Runx2 antibody (Abcam, ab76956) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000. Int J Mol Sci (2014) ncbi
mouse monoclonal
  • western blot; human
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples . FEBS J (2014) ncbi
mouse monoclonal
  • western blot; rat; 1:1000
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on rat samples at 1:1000. Cell Prolif (2014) ncbi
mouse monoclonal
  • immunocytochemistry; mouse
  • western blot; mouse
Abcam Runx2 antibody (Abcam, ab76956) was used in immunocytochemistry on mouse samples and in western blot on mouse samples . PLoS ONE (2014) ncbi
mouse monoclonal
  • western blot; human
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples . Int J Biol Sci (2013) ncbi
mouse monoclonal
  • immunohistochemistry - paraffin section; mouse; 1:1000
Abcam Runx2 antibody (Abcam, ab76956) was used in immunohistochemistry - paraffin section on mouse samples at 1:1000. Cell Tissue Res (2014) ncbi
mouse monoclonal
  • western blot; human
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples . PLoS ONE (2013) ncbi
mouse monoclonal
  • western blot; human; 1:1000
Abcam Runx2 antibody (Abcam, ab76956) was used in western blot on human samples at 1:1000. Cell Prolif (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (F-2)
  • western blot; human; loading ...; fig 4b
Santa Cruz Biotechnology Runx2 antibody (Santa, sc-390351) was used in western blot on human samples (fig 4b). Int J Med Sci (2022) ncbi
mouse monoclonal (F-2)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 1b
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 1b). Front Physiol (2022) ncbi
mouse monoclonal (F-2)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5d
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 5d). Commun Biol (2022) ncbi
mouse monoclonal (F-2)
  • western blot; bovine; loading ...; fig 3e
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in western blot on bovine samples (fig 3e). J Orthop Translat (2021) ncbi
mouse monoclonal (F-2)
  • immunohistochemistry - paraffin section; rat; loading ...; fig 3d
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in immunohistochemistry - paraffin section on rat samples (fig 3d). PLoS ONE (2021) ncbi
mouse monoclonal (C-12)
  • western blot; rat; loading ...; fig 1g
Santa Cruz Biotechnology Runx2 antibody (Santa, sc-390715) was used in western blot on rat samples (fig 1g). Aging (Albany NY) (2020) ncbi
mouse monoclonal (F-2)
  • immunocytochemistry; mouse; fig s7d
  • immunohistochemistry; human; 1:50; loading ...; fig s1b
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in immunocytochemistry on mouse samples (fig s7d) and in immunohistochemistry on human samples at 1:50 (fig s1b). Nat Commun (2020) ncbi
mouse monoclonal (F-2)
  • western blot; human; 1:500; loading ...; fig 2b
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, SC-390351) was used in western blot on human samples at 1:500 (fig 2b). Arthritis Res Ther (2019) ncbi
mouse monoclonal (27-K)
  • immunocytochemistry; human; loading ...; fig 4h
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-101145) was used in immunocytochemistry on human samples (fig 4h). Proc Natl Acad Sci U S A (2017) ncbi
mouse monoclonal (27-K)
  • western blot; rat; 1:400; loading ...; fig 7a
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-101145) was used in western blot on rat samples at 1:400 (fig 7a). Exp Ther Med (2017) ncbi
mouse monoclonal (C-12)
  • chromatin immunoprecipitation; mouse; loading ...; fig 6d
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, SC-390715) was used in chromatin immunoprecipitation on mouse samples (fig 6d). Sci Rep (2016) ncbi
mouse monoclonal (F-2)
  • western blot; rat; 1:500; fig 6
Santa Cruz Biotechnology Runx2 antibody (santa Cruz, sc-390351) was used in western blot on rat samples at 1:500 (fig 6). Int J Med Sci (2016) ncbi
mouse monoclonal (27-K)
  • western blot; human; loading ...; fig 7c
Santa Cruz Biotechnology Runx2 antibody (SantaCruz, sc-101145) was used in western blot on human samples (fig 7c). Oncogene (2016) ncbi
mouse monoclonal (27-K)
  • immunohistochemistry - paraffin section; human; 1:50; fig 1
In order to elucidate the role of Runx2 during the early stages of breast cancer and metastasis, Santa Cruz Biotechnology Runx2 antibody (Santa Cruz Biotechnology, sc-101145) was used in immunohistochemistry - paraffin section on human samples at 1:50 (fig 1). Pathol Oncol Res (2016) ncbi
mouse monoclonal (F-2)
  • immunohistochemistry - paraffin section; mouse; 1:100; fig 6
  • western blot; mouse; 1:2000; fig 3
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz, sc-390351) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6) and in western blot on mouse samples at 1:2000 (fig 3). Drug Des Devel Ther (2015) ncbi
mouse monoclonal (27-K)
  • immunohistochemistry - paraffin section; human
Santa Cruz Biotechnology Runx2 antibody (Santa Cruz Biotechnology, 27-K) was used in immunohistochemistry - paraffin section on human samples . Am J Pathol (2013) ncbi
Novus Biologicals
domestic rabbit polyclonal (8D5)
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2c
  • western blot; mouse; 1:2000; loading ...; fig 1k
Novus Biologicals Runx2 antibody (Novusbio, NBP1-77461) was used in immunohistochemistry - frozen section on mouse samples at 1:100 (fig 2c) and in western blot on mouse samples at 1:2000 (fig 1k). Nat Commun (2021) ncbi
domestic rabbit polyclonal (8D5)
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1e, 4a
Novus Biologicals Runx2 antibody (Novus, NBP1-77461) was used in immunohistochemistry - paraffin section on human samples at 1:200 (fig 1e, 4a). J Clin Med (2019) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; fig 7b
In order to create curcumin-eluting tissue scaffolds and explore their potential in bone tissue regeneration, Invitrogen Runx2 antibody (ThermoFisher Scientific, PA1-41519) was used in western blot on mouse samples (fig 7b). Biomed Mater (2016) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; 1:1000; fig 3a
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in western blot on mouse samples at 1:1000 (fig 3a). elife (2022) ncbi
domestic rabbit monoclonal (D1H7)
  • chromatin immunoprecipitation; human; 2 ug/ml; loading ...; fig 2c
  • western blot; human; loading ...; fig 2a
  • western blot; mouse; loading ...; fig 3e
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in chromatin immunoprecipitation on human samples at 2 ug/ml (fig 2c), in western blot on human samples (fig 2a) and in western blot on mouse samples (fig 3e). Mol Ther Nucleic Acids (2022) ncbi
domestic rabbit monoclonal (D1H7)
  • immunocytochemistry; human; 1:250; loading ...; fig 3a
  • western blot; human; 1:2000; loading ...; fig 2e
Cell Signaling Technology Runx2 antibody (CST, 8486) was used in immunocytochemistry on human samples at 1:250 (fig 3a) and in western blot on human samples at 1:2000 (fig 2e). Stem Cell Res Ther (2021) ncbi
domestic rabbit monoclonal (D1H7)
  • immunohistochemistry - paraffin section; mouse; 1:50; loading ...; fig 3g
  • western blot; mouse; 1:1000; loading ...; fig 7a
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in immunohistochemistry - paraffin section on mouse samples at 1:50 (fig 3g) and in western blot on mouse samples at 1:1000 (fig 7a). Commun Biol (2021) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; loading ...; fig 5a, s5b
  • western blot; human; loading ...; fig 6i
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486s) was used in western blot on mouse samples (fig 5a, s5b) and in western blot on human samples (fig 6i). Cancers (Basel) (2021) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; 1:1000; loading ...; fig s1b
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486S) was used in western blot on mouse samples at 1:1000 (fig s1b). Sci Adv (2019) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; human; 1:1000; loading ...; fig 2c
Cell Signaling Technology Runx2 antibody (Cell Signaling Technology, 8486) was used in western blot on human samples at 1:1000 (fig 2c). Cell Death Differ (2019) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; loading ...; fig 3d
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in western blot on mouse samples (fig 3d). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in western blot on mouse samples (fig 5a). Bone (2018) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; mouse; loading ...; fig 9e
Cell Signaling Technology Runx2 antibody (Cell Signaling Technologies, 8486) was used in western blot on mouse samples (fig 9e). Mol Cell Biol (2017) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; human; 1:1000; fig 6
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in western blot on human samples at 1:1000 (fig 6). Stem Cell Reports (2016) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; human; fig 1
  • western blot; mouse; fig 2
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486) was used in western blot on human samples (fig 1) and in western blot on mouse samples (fig 2). PLoS Genet (2016) ncbi
domestic rabbit monoclonal (D1H7)
  • western blot; rat; 1:1000; fig 11
Cell Signaling Technology Runx2 antibody (Cell Signaling, 8486S) was used in western blot on rat samples at 1:1000 (fig 11). Mol Med Rep (2016) ncbi
MBL International
monoclonal (8G5)
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1a
MBL International Runx2 antibody (MBL, D130-3) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1a). Nat Commun (2020) ncbi
monoclonal (8G5)
  • immunohistochemistry knockout validation; mouse; 1:200; loading ...; fig 3a
MBL International Runx2 antibody (MBL, D130-3) was used in immunohistochemistry knockout validation on mouse samples at 1:200 (fig 3a). J Cell Physiol (2019) ncbi
monoclonal (8G5)
  • western blot; mouse; loading ...; fig 3e
MBL International Runx2 antibody (MBL International, 8G5) was used in western blot on mouse samples (fig 3e). J Biol Chem (2018) ncbi
monoclonal (8G5)
  • immunoprecipitation; mouse; fig 2i
  • immunocytochemistry; mouse; fig 2i
  • western blot; mouse; fig 2i
  • immunoprecipitation; human; loading ...; fig 2d
  • western blot; human; loading ...; fig 2b
MBL International Runx2 antibody (MBL, D-130-3) was used in immunoprecipitation on mouse samples (fig 2i), in immunocytochemistry on mouse samples (fig 2i), in western blot on mouse samples (fig 2i), in immunoprecipitation on human samples (fig 2d) and in western blot on human samples (fig 2b). J Clin Invest (2016) ncbi
monoclonal (8G5)
  • western blot; mouse; 1:100; loading ...; fig 5b
MBL International Runx2 antibody (MBL, D130-3) was used in western blot on mouse samples at 1:100 (fig 5b). PLoS ONE (2016) ncbi
monoclonal (8G5)
  • immunoprecipitation; human
  • ELISA; human; 1:5000
MBL International Runx2 antibody (MBL, D130-3) was used in immunoprecipitation on human samples and in ELISA on human samples at 1:5000. Microvasc Res (2015) ncbi
Articles Reviewed
  1. Hojo H, Saito T, He X, Guo Q, Onodera S, Azuma T, et al. Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages. Cell Rep. 2022;40:111315 pubmed publisher
  2. Mu R, Chen B, Bi B, Yu H, Liu J, Li J, et al. LIM Mineralization Protein-1 Enhances the Committed Differentiation of Dental Pulp Stem Cells through the ERK1/2 and p38 MAPK Pathways and BMP Signaling. Int J Med Sci. 2022;19:1307-1319 pubmed publisher
  3. Shen L, Yu Y, Zhou Y, Pruett Miller S, Zhang G, Karner C. SLC38A2 provides proline to fulfill unique synthetic demands arising during osteoblast differentiation and bone formation. elife. 2022;11: pubmed publisher
  4. Ha N, Sun J, Bian Q, Wu D, Wang X. Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Front Physiol. 2022;13:819619 pubmed publisher
  5. Liu N, Lin Y, Li L, Lu J, Geng D, Zhang J, et al. gp130/STAT3 signaling is required for homeostatic proliferation and anabolism in postnatal growth plate and articular chondrocytes. Commun Biol. 2022;5:64 pubmed publisher
  6. Tsai H, Wang J, Hsu Y, Chiu Y, Lin C, Lu C, et al. miR-424/322 protects against abdominal aortic aneurysm formation by modulating the Smad2/3/runt-related transcription factor 2 axis. Mol Ther Nucleic Acids. 2022;27:656-669 pubmed publisher
  7. Zhang Y, McGrath K, Ayoub E, Kingsley P, Yu H, Fegan K, et al. Mds1CreERT2, an inducible Cre allele specific to adult-repopulating hematopoietic stem cells. Cell Rep. 2021;36:109562 pubmed publisher
  8. Gan Y, He J, Zhu J, Xu Z, Wang Z, Yan J, et al. Spatially defined single-cell transcriptional profiling characterizes diverse chondrocyte subtypes and nucleus pulposus progenitors in human intervertebral discs. Bone Res. 2021;9:37 pubmed publisher
  9. Jiang L, Yang Q, Gao J, Yang J, He J, Xin H, et al. BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/β-Catenin Pathway. Mol Cells. 2021;44:557-568 pubmed publisher
  10. Kim J, Kim M, Hong S, Kim E, Lee H, Jung H, et al. Albiflorin Promotes Osteoblast Differentiation and Healing of Rat Femoral Fractures Through Enhancing BMP-2/Smad and Wnt/β-Catenin Signaling. Front Pharmacol. 2021;12:690113 pubmed publisher
  11. Han H, Tian T, Huang G, Li D, Yang S. The lncRNA H19/miR-541-3p/Wnt/β-catenin axis plays a vital role in melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells. Aging (Albany NY). 2021;13:18257-18273 pubmed publisher
  12. Shen J, Sun Y, Liu X, Zhu Y, Bao B, Gao T, et al. EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling. Stem Cell Res Ther. 2021;12:415 pubmed publisher
  13. Zhang D, Huang J, Sun X, Chen H, Huang S, Yang J, et al. Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway. Nat Commun. 2021;12:4391 pubmed publisher
  14. Lee B, Hong S, Kim M, Kim E, Park H, Jung H, et al. Lycii radicis cortex inhibits glucocorticoid‑induced bone loss by downregulating Runx2 and BMP‑2 expression. Int J Mol Med. 2021;48: pubmed publisher
  15. Qin H, Zhao X, Hu Y, Wang S, Ma Y, He S, et al. Inhibition of SDF-1/CXCR4 Axis to Alleviate Abnormal Bone Formation and Angiogenesis Could Improve the Subchondral Bone Microenvironment in Osteoarthritis. Biomed Res Int. 2021;2021:8852574 pubmed publisher
  16. Yen Y, Chien M, Wu P, Hung S. PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation. Commun Biol. 2021;4:658 pubmed publisher
  17. Zhang W, Dong Z, Li D, Li B, Liu Y, Zheng X, et al. Cathepsin K deficiency promotes alveolar bone regeneration by promoting jaw bone marrow mesenchymal stem cells proliferation and differentiation via glycolysis pathway. Cell Prolif. 2021;54:e13058 pubmed publisher
  18. Olsen R, Ireland A, Kastner D, Groves S, Spainhower K, Pozo K, et al. ASCL1 represses a SOX9+ neural crest stem-like state in small cell lung cancer. Genes Dev. 2021;35:847-869 pubmed publisher
  19. Yuan C, Chen H, Tu S, Huang H, Pan Y, Gui X, et al. A systematic dissection of the epigenomic heterogeneity of lung adenocarcinoma reveals two different subclasses with distinct prognosis and core regulatory networks. Genome Biol. 2021;22:156 pubmed publisher
  20. Chen Q, Liu X, Wang D, Zheng J, Chen L, Xie Q, et al. Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis. Front Cell Dev Biol. 2021;9:663037 pubmed publisher
  21. Huang J, Li R, Yang J, Cai M, Lee Y, Wang A, et al. Bioadaptation of implants to In vitro and In vivo oxidative stress pathological conditions via nanotopography-induced FoxO1 signaling pathways to enhance Osteoimmunal regeneration. Bioact Mater. 2021;6:3164-3176 pubmed publisher
  22. Xu G, Hu X, Han L, Zhao Y, Li Z. The construction of a novel xenograft bovine bone scaffold, (DSS)6-liposome/CKIP-1 siRNA/calcine bone and its osteogenesis evaluation on skull defect in rats. J Orthop Translat. 2021;28:74-82 pubmed publisher
  23. Brito V, Patrocinio M, Sousa M, Barreto A, Frasnelli S, Lara V, et al. Mast cells contribute to alveolar bone loss in Spontaneously Hypertensive Rats with periodontal disease regulating cytokines production. PLoS ONE. 2021;16:e0247372 pubmed publisher
  24. Feng Y, Liu S, Zha R, Sun X, Li K, ROBLING A, et al. Mechanical Loading-Driven Tumor Suppression Is Mediated by Lrp5-Dependent and Independent Mechanisms. Cancers (Basel). 2021;13: pubmed publisher
  25. Ofiteru A, Becheru D, Gharbia S, Baltă C, Herman H, Mladin B, et al. Qualifying Osteogenic Potency Assay Metrics for Human Multipotent Stromal Cells: TGF-β2 a Telling Eligible Biomarker. Cells. 2020;9: pubmed publisher
  26. Gu Z, Xie D, Ding R, Huang C, Qiu Y. GPR173 agonist phoenixin 20 promotes osteoblastic differentiation of MC3T3-E1 cells. Aging (Albany NY). 2020;13:4976-4985 pubmed publisher
  27. He F, Li L, Li P, Deng Y, Yang Y, Deng Y, et al. Cyclooxygenase-2/sclerostin mediates TGF-β1-induced calcification in vascular smooth muscle cells and rats undergoing renal failure. Aging (Albany NY). 2020;12:21220-21235 pubmed publisher
  28. Kim J, Yang Y, Park K, Ge X, Xu R, Li N, et al. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation. Nat Commun. 2020;11:2289 pubmed publisher
  29. Bhat O, Yuan X, Camus S, Salloum F, Li P. Abnormal Lysosomal Positioning and Small Extracellular Vesicle Secretion in Arterial Stiffening and Calcification of Mice Lacking Mucolipin 1 Gene. Int J Mol Sci. 2020;21: pubmed publisher
  30. Zhao W, Zhang W, Ma H, Yang M. NIPA2 regulates osteoblast function by modulating mitophagy in type 2 diabetes osteoporosis. Sci Rep. 2020;10:3078 pubmed publisher
  31. Yang X, Yang J, Lei P, Wen T. LncRNA MALAT1 shuttled by bone marrow-derived mesenchymal stem cells-secreted exosomes alleviates osteoporosis through mediating microRNA-34c/SATB2 axis. Aging (Albany NY). 2019;11:8777-8791 pubmed publisher
  32. Darrieutort Laffite C, Arnolfo P, Garraud T, Adrait A, Coute Y, Louarn G, et al. Rotator Cuff Tenocytes Differentiate into Hypertrophic Chondrocyte-Like Cells to Produce Calcium Deposits in an Alkaline Phosphatase-Dependent Manner. J Clin Med. 2019;8: pubmed publisher
  33. Iwayama T, Okada T, Ueda T, Tomita K, Matsumoto S, Takedachi M, et al. Osteoblastic lysosome plays a central role in mineralization. Sci Adv. 2019;5:eaax0672 pubmed publisher
  34. Mokuda S, Nakamichi R, Matsuzaki T, Ito Y, Sato T, Miyata K, et al. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. Nat Commun. 2019;10:2429 pubmed publisher
  35. Li J, Wang P, Xie Z, Wang S, Cen S, Li M, et al. TRAF4 positively regulates the osteogenic differentiation of mesenchymal stem cells by acting as an E3 ubiquitin ligase to degrade Smurf2. Cell Death Differ. 2019;: pubmed publisher
  36. Guo L, Wei X, Zhang Z, Wang X, Wang C, Li P, et al. Ipriflavone attenuates the degeneration of cartilage by blocking the Indian hedgehog pathway. Arthritis Res Ther. 2019;21:109 pubmed publisher
  37. Nakanishi M, Mitchell R, Benoit Y, Orlando L, Reid J, Shimada K, et al. Human Pluripotency Is Initiated and Preserved by a Unique Subset of Founder Cells. Cell. 2019;177:910-924.e22 pubmed publisher
  38. Zhou N, Gutierrez Uzquiza A, Zheng X, Chang R, Vogl D, Garfall A, et al. RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019;: pubmed publisher
  39. Lin X, Zhan J, Zhong J, Wang Y, Wang Y, Li S, et al. lncRNA-ES3/miR-34c-5p/BMF axis is involved in regulating high-glucose-induced calcification/senescence of VSMCs. Aging (Albany NY). 2019;11:523-535 pubmed publisher
  40. Chen X, Zhi X, Wang J, Su J. RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation. Bone Res. 2018;6:34 pubmed publisher
  41. Liao L, Zhang S, Zhou G, Ye L, Huang J, Zhao L, et al. Deletion of Runx2 in condylar chondrocytes disrupts TMJ tissue homeostasis. J Cell Physiol. 2019;234:3436-3444 pubmed publisher
  42. Godfrey T, Wildman B, Beloti M, Kemper A, Ferraz E, Roy B, et al. The microRNA-23a cluster regulates the developmental HoxA cluster function during osteoblast differentiation. J Biol Chem. 2018;293:17646-17660 pubmed publisher
  43. Tay L, Krishnan V, Sankar H, Chong Y, Chuang L, Tan T, et al. RUNX Poly(ADP-Ribosyl)ation and BLM Interaction Facilitate the Fanconi Anemia Pathway of DNA Repair. Cell Rep. 2018;24:1747-1755 pubmed publisher
  44. Ghanem L, Kromer A, Silverman I, Ji X, Gazzara M, Nguyen N, et al. Poly(C)-Binding Protein Pcbp2 Enables Differentiation of Definitive Erythropoiesis by Directing Functional Splicing of the Runx1 Transcript. Mol Cell Biol. 2018;38: pubmed publisher
  45. Yang R, Yu T, Kou X, Gao X, Chen C, Liu D, et al. Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter. Nat Commun. 2018;9:2143 pubmed publisher
  46. Liu L, Liu K, Yan Y, Chu Z, Tang Y, Tang C. Two Transcripts of FBXO5 Promote Migration and Osteogenic Differentiation of Human Periodontal Ligament Mesenchymal Stem Cells. Biomed Res Int. 2018;2018:7849294 pubmed publisher
  47. Pan B, Wu L, Pan L, Yang Y, Li H, Dai Y, et al. Up-regulation of microRNA-340 promotes osteosarcoma cell apoptosis while suppressing proliferation, migration, and invasion by inactivating the CTNNB1-mediated Notch signaling pathway. Biosci Rep. 2018;38: pubmed publisher
  48. Bergiers I, Andrews T, Vargel Bölükbaşı Ö, Buness A, Janosz E, Lopez Anguita N, et al. Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis. elife. 2018;7: pubmed publisher
  49. Chen X, Chen J, Xu D, Zhao S, Song H, Peng Y. Effects of Osteoglycin (OGN) on treating senile osteoporosis by regulating MSCs. BMC Musculoskelet Disord. 2017;18:423 pubmed publisher
  50. Fujita S, Mukai T, Mito T, Kodama S, Nagasu A, Kittaka M, et al. Pharmacological inhibition of tankyrase induces bone loss in mice by increasing osteoclastogenesis. Bone. 2018;106:156-166 pubmed publisher
  51. Jiang X, Hawkins J, Lee J, Lizama C, Bos F, Zape J, et al. Let-7 microRNA-dependent control of leukotriene signaling regulates the transition of hematopoietic niche in mice. Nat Commun. 2017;8:128 pubmed publisher
  52. Hadden W, Young J, Holle A, McFetridge M, Kim D, Wijesinghe P, et al. Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels. Proc Natl Acad Sci U S A. 2017;114:5647-5652 pubmed publisher
  53. Li S, Wang J. Salvianolic acid B prevents steroid-induced osteonecrosis of the femoral head via PPAR? expression in rats. Exp Ther Med. 2017;13:651-656 pubmed publisher
  54. Kasaai B, Caolo V, Peacock H, Lehoux S, Gomez Perdiguero E, Luttun A, et al. Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Sci Rep. 2017;7:43817 pubmed publisher
  55. Fitter S, Matthews M, Martin S, Xie J, Ooi S, Walkley C, et al. mTORC1 Plays an Important Role in Skeletal Development by Controlling Preosteoblast Differentiation. Mol Cell Biol. 2017;37: pubmed publisher
  56. Rimando M, Wu H, Liu Y, Lee C, Kuo S, Lo Y, et al. Glucocorticoid receptor and Histone deacetylase 6 mediate the differential effect of dexamethasone during osteogenesis of mesenchymal stromal cells (MSCs). Sci Rep. 2016;6:37371 pubmed publisher
  57. Matsumoto Y, La Rose J, Kent O, Wagner M, Narimatsu M, Levy A, et al. Reciprocal stabilization of ABL and TAZ regulates osteoblastogenesis through transcription factor RUNX2. J Clin Invest. 2016;126:4482-4496 pubmed publisher
  58. Jain S, Krishna Meka S, Chatterjee K. Curcumin eluting nanofibers augment osteogenesis toward phytochemical based bone tissue engineering. Biomed Mater. 2016;11:055007 pubmed
  59. Huang X, ZHu B, Wang X, Xiao R, Wang C. Three-dimensional co-culture of mesenchymal stromal cells and differentiated osteoblasts on human bio-derived bone scaffolds supports active multi-lineage hematopoiesis in vitro: Functional implication of the biomimetic HSC niche. Int J Mol Med. 2016;38:1141-51 pubmed publisher
  60. Li P, Xu Y, Gan Y, Song L, Zhang C, Wang L, et al. Role of the ERK1/2 Signaling Pathway in Osteogenesis of Rat Tendon-Derived Stem Cells in Normoxic and Hypoxic Cultures. Int J Med Sci. 2016;13:629-37 pubmed publisher
  61. Fan C, Jia L, Zheng Y, Jin C, Liu Y, Liu H, et al. MiR-34a Promotes Osteogenic Differentiation of Human Adipose-Derived Stem Cells via the RBP2/NOTCH1/CYCLIN D1 Coregulatory Network. Stem Cell Reports. 2016;7:236-48 pubmed publisher
  62. Jiang S, Chen G, Feng L, Jiang Z, Yu M, Bao J, et al. Disruption of kif3a results in defective osteoblastic differentiation in dental mesenchymal stem/precursor cells via the Wnt signaling pathway. Mol Med Rep. 2016;14:1891-900 pubmed publisher
  63. Kam J, Dumontier E, Baim C, Brignall A, Mendes da Silva D, Cowan M, et al. RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016;143:1534-46 pubmed publisher
  64. Caron M, Emans P, Sanen K, Surtel D, Cremers A, Ophelders D, et al. The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells. PLoS ONE. 2016;11:e0153162 pubmed publisher
  65. Yan B, Zhang Z, Jin D, Cai C, Jia C, Liu W, et al. mTORC1 regulates PTHrP to coordinate chondrocyte growth, proliferation and differentiation. Nat Commun. 2016;7:11151 pubmed publisher
  66. Shin M, He Y, Marrogi E, Piperdi S, Ren L, Khanna C, et al. A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells. PLoS Genet. 2016;12:e1005884 pubmed publisher
  67. Ying M, Zhang L, Zhou Q, Shao X, Cao J, Zhang N, et al. The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα. Oncogene. 2016;35:4358-67 pubmed publisher
  68. El Gendi S, Mostafa M. Runx2 Expression as a Potential Prognostic Marker in Invasive Ductal Breast Carcinoma. Pathol Oncol Res. 2016;22:461-70 pubmed publisher
  69. Wang Y, Zhu G, Wang J, Chen J. Irradiation alters the differentiation potential of bone marrow mesenchymal stem cells. Mol Med Rep. 2016;13:213-23 pubmed publisher
  70. Li S, TANG J, Chen J, Zhang P, Wang T, Chen T, et al. Regulation of bone formation by baicalein via the mTORC1 pathway. Drug Des Devel Ther. 2015;9:5169-83 pubmed publisher
  71. Uchiyama T, Kawabata H, Miura Y, Yoshioka S, Iwasa M, Yao H, et al. The role of growth differentiation factor 15 in the pathogenesis of primary myelofibrosis. Cancer Med. 2015;4:1558-72 pubmed publisher
  72. Koh F, Lizama C, Wong P, Hawkins J, Zovein A, Ramalho Santos M. Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proc Natl Acad Sci U S A. 2015;112:E1734-43 pubmed publisher
  73. Guan J, Zhang J, Zhu Z, Niu X, Guo S, Wang Y, et al. Bone morphogenetic protein 2 gene transduction enhances the osteogenic potential of human urine-derived stem cells. Stem Cell Res Ther. 2015;6:5 pubmed publisher
  74. Van Bragt M, Hu X, Xie Y, Li Z. RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells. elife. 2014;3:e03881 pubmed publisher
  75. Mochin M, Underwood K, Cooper B, McLenithan J, Pierce A, Nalvarte C, et al. Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells. Microvasc Res. 2015;97:55-64 pubmed publisher
  76. Li X, Liang W, Ye H, Weng X, Liu F, Liu X. Overexpression of Shox2 leads to congenital dysplasia of the temporomandibular joint in mice. Int J Mol Sci. 2014;15:13135-50 pubmed publisher
  77. Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed publisher
  78. Wang Y, Li J, Song W, Yu J. Mineral trioxide aggregate upregulates odonto/osteogenic capacity of bone marrow stromal cells from craniofacial bones via JNK and ERK MAPK signalling pathways. Cell Prolif. 2014;47:241-8 pubmed publisher
  79. Wang H, Sun W, Ma J, Pan Y, Wang L, Zhang W. Polycystin-1 mediates mechanical strain-induced osteoblastic mechanoresponses via potentiation of intracellular calcium and Akt/?-catenin pathway. PLoS ONE. 2014;9:e91730 pubmed publisher
  80. Dai J, Li Y, Zhou H, Chen J, Chen M, Xiao Z. Genistein promotion of osteogenic differentiation through BMP2/SMAD5/RUNX2 signaling. Int J Biol Sci. 2013;9:1089-98 pubmed publisher
  81. Li X, Liu H, Gu S, Liu C, Sun C, Zheng Y, et al. Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice. Cell Tissue Res. 2014;355:345-54 pubmed publisher
  82. Kazantseva J, Kivil A, Tints K, Kazantseva A, Neuman T, Palm K. Alternative splicing targeting the hTAF4-TAFH domain of TAF4 represses proliferation and accelerates chondrogenic differentiation of human mesenchymal stem cells. PLoS ONE. 2013;8:e74799 pubmed publisher
  83. Andersen T, Abdelgawad M, Kristensen H, Hauge E, Rolighed L, Bollerslev J, et al. Understanding coupling between bone resorption and formation: are reversal cells the missing link?. Am J Pathol. 2013;183:235-46 pubmed publisher
  84. Wang L, Yan M, Wang Y, Lei G, Yu Y, Zhao C, et al. Proliferation and osteo/odontoblastic differentiation of stem cells from dental apical papilla in mineralization-inducing medium containing additional KH(2)PO(4). Cell Prolif. 2013;46:214-22 pubmed publisher