This is a Validated Antibody Database (VAD) review about mouse Rraga, based on 15 published articles (read how Labome selects the articles), using Rraga antibody in all methods. It is aimed to help Labome visitors find the most suited Rraga antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rraga synonym: 1300010C19Rik; AI255374; FIP-1; RAGA

Knockout validation
Cell Signaling Technology
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology Rraga antibody (Cell Signaling Technology, 4357) was used in western blot knockout validation on human samples at 1:1000 (fig 3e). Nat Commun (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig s2c
Cell Signaling Technology Rraga antibody (CST, D8B5) was used in western blot knockout validation on human samples (fig s2c). Science (2019) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig 1d
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot knockout validation on human samples (fig 1d). Nature (2017) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; mouse; 1:1000; fig s1a
  • immunocytochemistry knockout validation; human; 1:100; fig s10c
  • western blot; human; fig s9e
Cell Signaling Technology Rraga antibody (Cell signaling, 4357) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a), in immunocytochemistry knockout validation on human samples at 1:100 (fig s10c) and in western blot on human samples (fig s9e). Science (2015) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; 1:1000; loading ...; fig 3e
Cell Signaling Technology Rraga antibody (Cell Signaling Technology, 4357) was used in western blot knockout validation on human samples at 1:1000 (fig 3e). Nat Commun (2021) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; mouse; loading ...; fig 4d
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot on mouse samples (fig 4d). Front Immunol (2020) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig s2c
Cell Signaling Technology Rraga antibody (CST, D8B5) was used in western blot knockout validation on human samples (fig s2c). Science (2019) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; 1:1000; loading ...; fig 1s1b
Cell Signaling Technology Rraga antibody (Cell signaling, 4357) was used in western blot on human samples at 1:1000 (fig 1s1b). elife (2019) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; 1:1000; loading ...; fig 4a
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot on human samples at 1:1000 (fig 4a). Nat Commun (2018) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; human; loading ...; fig 1d
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot knockout validation on human samples (fig 1d). Nature (2017) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; fig 6a
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot on human samples (fig 6a). Cell (2016) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; 1:1000; fig s2
In order to elucidate the mechanisms by which mutant IDH1/2 contributes to oncogenesis, Cell Signaling Technology Rraga antibody (Cell signaling, D8B5) was used in western blot on human samples at 1:1000 (fig s2). Nat Commun (2016) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; fig 3
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in western blot on human samples (fig 3). PLoS Genet (2016) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; rat; fig 3
Cell Signaling Technology Rraga antibody (Cell Signaling Technology, 4357) was used in western blot on rat samples (fig 3). J Nutr (2015) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot knockout validation; mouse; 1:1000; fig s1a
  • immunocytochemistry knockout validation; human; 1:100; fig s10c
  • western blot; human; fig s9e
Cell Signaling Technology Rraga antibody (Cell signaling, 4357) was used in western blot knockout validation on mouse samples at 1:1000 (fig s1a), in immunocytochemistry knockout validation on human samples at 1:100 (fig s10c) and in western blot on human samples (fig s9e). Science (2015) ncbi
domestic rabbit monoclonal (D8B5)
  • immunoprecipitation; human; fig 1
  • western blot; human; fig 1
Cell Signaling Technology Rraga antibody (Cell signaling, 4357) was used in immunoprecipitation on human samples (fig 1) and in western blot on human samples (fig 1). Nature (2015) ncbi
domestic rabbit monoclonal (D8B5)
  • immunoprecipitation; human; fig 5
  • western blot; human; fig s6
Cell Signaling Technology Rraga antibody (Cell Signaling, 4357) was used in immunoprecipitation on human samples (fig 5) and in western blot on human samples (fig s6). Cell (2014) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human
Cell Signaling Technology Rraga antibody (Cell Signaling Technology, 4357) was used in western blot on human samples . J Biol Chem (2014) ncbi
domestic rabbit monoclonal (D8B5)
  • western blot; human; 1:500
Cell Signaling Technology Rraga antibody (Cell Signaling Technology, 4357) was used in western blot on human samples at 1:500. J Virol (2013) ncbi
Articles Reviewed
  1. Zhang Y, Swanda R, Nie L, Liu X, Wang C, Lee H, et al. mTORC1 couples cyst(e)ine availability with GPX4 protein synthesis and ferroptosis regulation. Nat Commun. 2021;12:1589 pubmed publisher
  2. Ma C, Hunt J, Selenica M, Sanneh A, Sandusky Beltran L, Watler M, et al. Arginase 1 Insufficiency Precipitates Amyloid-β Deposition and Hastens Behavioral Impairment in a Mouse Model of Amyloidosis. Front Immunol. 2020;11:582998 pubmed publisher
  3. Rogala K, Gu X, Kedir J, Abu Remaileh M, Bianchi L, Bottino A, et al. Structural basis for the docking of mTORC1 on the lysosomal surface. Science. 2019;366:468-475 pubmed publisher
  4. Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher
  5. Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed publisher
  6. Peng M, Yin N, Li M. SZT2 dictates GATOR control of mTORC1 signalling. Nature. 2017;543:433-437 pubmed publisher
  7. Wu L, Zhou B, Oshiro Rapley N, Li M, Paulo J, Webster C, et al. An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer. Cell. 2016;167:1705-1718.e13 pubmed publisher
  8. Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
  9. Chen J, Huang C, Zhang B, Yin S, Liang J, Xu C, et al. Mutations of RagA GTPase in mTORC1 Pathway Are Associated with Autosomal Dominant Cataracts. PLoS Genet. 2016;12:e1006090 pubmed publisher
  10. Kimball S, Ravi S, Gordon B, Dennis M, Jefferson L. Amino Acid-Induced Activation of mTORC1 in Rat Liver Is Attenuated by Short-Term Consumption of a High-Fat Diet. J Nutr. 2015;145:2496-502 pubmed publisher
  11. Jewell J, Kim Y, Russell R, Yu F, Park H, Plouffe S, et al. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Science. 2015;347:194-8 pubmed publisher
  12. Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  13. Peng M, Yin N, Li M. Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling. Cell. 2014;159:122-133 pubmed publisher
  14. Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher
  15. McNulty S, Flint M, Nichol S, Spiropoulou C. Host mTORC1 signaling regulates andes virus replication. J Virol. 2013;87:912-22 pubmed publisher