This is a Validated Antibody Database (VAD) review about mouse Rpa2, based on 66 published articles (read how Labome selects the articles), using Rpa2 antibody in all methods. It is aimed to help Labome visitors find the most suited Rpa2 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rpa2 synonym: AA409079; AI325195; AU020965; RPA34; Rf-A2

Abcam
mouse monoclonal (9H8)
  • western blot; human; 1:1000; loading ...; fig s4a
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples at 1:1000 (fig s4a). EMBO Mol Med (2022) ncbi
domestic rabbit monoclonal (EPR2877Y)
  • western blot; human; 1:1000; loading ...
Abcam Rpa2 antibody (Abcam, ab76420) was used in western blot on human samples at 1:1000. elife (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:10,000; loading ...; fig 2d
Abcam Rpa2 antibody (Abcam, ab10359) was used in western blot on human samples at 1:10,000 (fig 2d). Nat Commun (2021) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 5h
Abcam Rpa2 antibody (Abcam, Ab2175) was used in western blot on human samples (fig 5h). Mol Cell (2020) ncbi
mouse monoclonal (9H8)
  • other; human; 1:250; loading ...; fig 5b
Abcam Rpa2 antibody (Abcam, ab2175) was used in other on human samples at 1:250 (fig 5b). elife (2020) ncbi
mouse monoclonal (9H8)
  • western blot; human; 1:1000; loading ...; fig 4a
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples at 1:1000 (fig 4a). EMBO Mol Med (2019) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; loading ...; fig 7g
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig 7g). Mol Cell (2019) ncbi
mouse monoclonal (9H8)
  • western blot; human; loading ...; fig 4g
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples (fig 4g). Cell (2019) ncbi
mouse monoclonal (9H8)
  • flow cytometry; human; 1:50; loading ...; fig s9a
Abcam Rpa2 antibody (Abcam, ab2175) was used in flow cytometry on human samples at 1:50 (fig s9a). Nature (2018) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:250; loading ...; fig 1a
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:250 (fig 1a). Nucleic Acids Res (2018) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:500; loading ...; fig s3b
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:500 (fig s3b). Science (2017) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; mouse; 1:300; loading ...; fig 4d
In order to test whether the attenuation of non-homologous end joining repair is sufficient to compromise homologous recombination in DEK knockout mice, Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on mouse samples at 1:300 (fig 4d). Sci Rep (2017) ncbi
mouse monoclonal (9H8)
  • western blot; human; loading ...; fig 2g
Abcam Rpa2 antibody (Abcam, Ab2175) was used in western blot on human samples (fig 2g). Genes Dev (2017) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; loading ...; fig s2b
In order to research the role of TOPBP1 in DNA homologous recombination, Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig s2b). J Cell Biol (2017) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig st1
In order to analyze the effect of CX-5461 as a G-quadruplex DNA stabilizer, Abcam Rpa2 antibody (Abcam, ab61065) was used in western blot on human samples at 1:1000 (fig st1). Nat Commun (2017) ncbi
mouse monoclonal (9H8)
  • western blot; human; loading ...; fig 1c
In order to identify interacting proteins of TTF-1 and their role in lung adenocarcinoma cell survival., Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples (fig 1c). Oncogene (2017) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; loading ...; fig 3a
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig 3a). Genes Dev (2017) ncbi
mouse monoclonal (9H8)
  • western blot; human; 1:2000; fig 3d
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples at 1:2000 (fig 3d). Nat Commun (2016) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples . Proc Natl Acad Sci U S A (2016) ncbi
mouse monoclonal (9H8)
  • western blot; mouse; 1:1000; loading ...; fig 5b
In order to investigate the link between NEAT1 paraspeckles, p53 biology, and tumorigenesis, Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on mouse samples at 1:1000 (fig 5b). Nat Med (2016) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 5
Abcam Rpa2 antibody (Abcam, 2175) was used in western blot on human samples (fig 5). Nucleic Acids Res (2016) ncbi
mouse monoclonal (9H8)
  • flow cytometry; human; fig 1
Abcam Rpa2 antibody (Abcam, ab2175) was used in flow cytometry on human samples (fig 1). Nucleic Acids Res (2016) ncbi
mouse monoclonal (9H8)
  • western blot; human; 1:1000; fig 3
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples at 1:1000 (fig 3). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Abcam Rpa2 antibody (Abcam, ab61065) was used in western blot on human samples (fig 1). J Cell Biol (2016) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; fig 3
  • western blot; human; fig 1
In order to investigate the role of topoisomerase IIbeta-binding protein 1 in DNA repair and its contribution to cancer, Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig 3) and in western blot on human samples (fig 1). J Cell Biol (2016) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; fig 5
In order to study how miR-622 promotes resistance to PARP inhibitors and platinum in BRCA1 mutant high-grade serous ovarian carcinomas, Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig 5). Cell Rep (2016) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:200; fig 3
  • western blot; human; 1:200; fig 3
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:200 (fig 3) and in western blot on human samples at 1:200 (fig 3). Nat Commun (2016) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 2d
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples (fig 2d). Nucleic Acids Res (2016) ncbi
domestic rabbit monoclonal (EPR2846(2))
  • immunocytochemistry; human; fig 3
Abcam Rpa2 antibody (Abcam, ab109394) was used in immunocytochemistry on human samples (fig 3). J Cell Biol (2016) ncbi
domestic rabbit monoclonal (EPR2877Y)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 3
Abcam Rpa2 antibody (Abcam, ab76420) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 3). J Cell Biol (2016) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 2
In order to report that inappropriate activation of CDK2 in S phase affects checkpoint kinase 1 inhibitor sensitivity in a subset of cell lines, Abcam Rpa2 antibody (abcam, ab-2175) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
domestic rabbit monoclonal (EPR2846(2))
  • western blot; human; 1:1000
Abcam Rpa2 antibody (Abcam, ab109394) was used in western blot on human samples at 1:1000. Nucleic Acids Res (2016) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:1000; fig 3
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:1000 (fig 3). Oncotarget (2015) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 4
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples (fig 4). Mol Cell Biol (2015) ncbi
mouse monoclonal (9H8)
  • flow cytometry; human; 1:200; fig 6
Abcam Rpa2 antibody (Abcam, ab2175) was used in flow cytometry on human samples at 1:200 (fig 6). PLoS Genet (2015) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:100; fig 1
Abcam Rpa2 antibody (Abcam, ab2175-500) was used in immunocytochemistry on human samples at 1:100 (fig 1). DNA Repair (Amst) (2015) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human
  • western blot; human
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples and in western blot on human samples . DNA Repair (Amst) (2015) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:100
Abcam Rpa2 antibody (Abcam, Ab2175) was used in immunocytochemistry on human samples at 1:100. Nucleic Acids Res (2014) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human
  • western blot; human
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples and in western blot on human samples . elife (2014) ncbi
mouse monoclonal (9H8)
  • western blot; human
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples . Genes Dev (2014) ncbi
mouse monoclonal (9H8)
  • western blot; human
Abcam Rpa2 antibody (Abcam, ab2175) was used in western blot on human samples . Cell Res (2014) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 3a
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples (fig 1) and in western blot on human samples (fig 3a). J Biol Chem (2014) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:200; fig 2b
  • western blot; human; 1:1000
In order to study the effect of ASF1 depletion on the alternative lengthening of telomeres, Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:200 (fig 2b) and in western blot on human samples at 1:1000. Nat Struct Mol Biol (2014) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:200
Abcam Rpa2 antibody (Abcam, ab2175) was used in immunocytochemistry on human samples at 1:200. PLoS ONE (2013) ncbi
mouse monoclonal (9H8)
  • immunocytochemistry; human; 1:500
Abcam Rpa2 antibody (Abcam, Ab2175) was used in immunocytochemistry on human samples at 1:500. Nucleic Acids Res (2013) ncbi
Santa Cruz Biotechnology
mouse monoclonal (9H8)
  • western blot; human; loading ...; fig 4s2b
Santa Cruz Biotechnology Rpa2 antibody (Santa Cruz, sc-56770) was used in western blot on human samples (fig 4s2b). elife (2020) ncbi
mouse monoclonal (9H8)
  • western blot; human; 1:1000; loading ...; fig 5d
Santa Cruz Biotechnology Rpa2 antibody (Santa Cruz, sc56770) was used in western blot on human samples at 1:1000 (fig 5d). Oncogene (2016) ncbi
mouse monoclonal (9H8)
  • western blot; human; fig 8
Santa Cruz Biotechnology Rpa2 antibody (Santa Cruz, sc-56770) was used in western blot on human samples (fig 8). Nucleic Acids Res (2016) ncbi
mouse monoclonal (9H8)
  • western blot; mouse; 1:100; fig 6
Santa Cruz Biotechnology Rpa2 antibody (Santa Cruz, sc-56770) was used in western blot on mouse samples at 1:100 (fig 6). Cell Cycle (2015) ncbi
Novus Biologicals
domestic rabbit polyclonal (H1beta234)
  • western blot; human; fig 2
In order to report that inappropriate activation of CDK2 in S phase affects checkpoint kinase 1 inhibitor sensitivity in a subset of cell lines, Novus Biologicals Rpa2 antibody (Novus, NBP 1-23017) was used in western blot on human samples (fig 2). Oncotarget (2016) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; human; fig s10
In order to investigate how the von Hippel-Lindau tumor suppressor gene regulates metabolism in renal cell carcinoma, Invitrogen Rpa2 antibody (Thermo Fisher Scientific, PA5-22256) was used in western blot on human samples (fig s10). J Clin Invest (2017) ncbi
Cell Signaling Technology
rat monoclonal (4E4)
  • immunocytochemistry; human; 1:1000; loading ...; fig 4b, 5b
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208S) was used in immunocytochemistry on human samples at 1:1000 (fig 4b, 5b). Sci Rep (2021) ncbi
rat monoclonal (4E4)
  • immunohistochemistry; mouse; 1:100; loading ...; fig s7-3b
Cell Signaling Technology Rpa2 antibody (Cell Signalling, 2208S) was used in immunohistochemistry on mouse samples at 1:100 (fig s7-3b). elife (2020) ncbi
rat monoclonal (4E4)
  • immunohistochemistry; mouse; loading ...; fig 5a
Cell Signaling Technology Rpa2 antibody (Cell signaling technology;, 2208) was used in immunohistochemistry on mouse samples (fig 5a). Nat Commun (2020) ncbi
rat monoclonal (4E4)
  • western blot; mouse; 1:1000; loading ...; fig s3d
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in western blot on mouse samples at 1:1000 (fig s3d). Nat Commun (2019) ncbi
rat monoclonal (4E4)
  • western blot; mouse; 1:500; loading ...; fig 3c
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208T) was used in western blot on mouse samples at 1:500 (fig 3c). Nat Commun (2019) ncbi
rat monoclonal (4E4)
  • immunocytochemistry; mouse; loading ...; fig 5c
Cell Signaling Technology Rpa2 antibody (Cell signaling, 2208S) was used in immunocytochemistry on mouse samples (fig 5c). Stem Cell Reports (2019) ncbi
rat monoclonal (4E4)
  • immunocytochemistry; mouse; 1:250; loading ...; fig 1b
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in immunocytochemistry on mouse samples at 1:250 (fig 1b). Sci Adv (2019) ncbi
rat monoclonal (4E4)
  • immunohistochemistry; mouse; 1:100; loading ...; fig 1i
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208T) was used in immunohistochemistry on mouse samples at 1:100 (fig 1i). Sci Adv (2019) ncbi
rat monoclonal (4E4)
  • other; human; loading ...; fig 4c
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in other on human samples (fig 4c). Cancer Cell (2018) ncbi
rat monoclonal (4E4)
  • western blot; mouse; loading ...; fig 5b
In order to engineer and characterize a second-generation, high-affinity AXL decoy receptor, Cell Signaling Technology Rpa2 antibody (CST, 2208) was used in western blot on mouse samples (fig 5b). J Clin Invest (2017) ncbi
rat monoclonal (4E4)
  • immunohistochemistry; mouse; 1:100; fig 1
  • western blot; mouse
Cell Signaling Technology Rpa2 antibody (Cell Signalling, 2208S) was used in immunohistochemistry on mouse samples at 1:100 (fig 1) and in western blot on mouse samples . Nat Commun (2016) ncbi
rat monoclonal (4E4)
  • western blot; human; fig 5
In order to study NPM-ALK-amplified cell lines resistant to ALK tyrosine kinase inhibitors, Cell Signaling Technology Rpa2 antibody (Cell Signaling Technology, 2208) was used in western blot on human samples (fig 5). Oncogene (2016) ncbi
rat monoclonal (4E4)
  • western blot; human; 1:1000; fig 8
In order to assess links between telomere-dysfunction and centrosome defects in early breast carcinogenesis, Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in western blot on human samples at 1:1000 (fig 8). Oncotarget (2015) ncbi
rat monoclonal (4E4)
  • immunocytochemistry; mouse
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 4E4) was used in immunocytochemistry on mouse samples . J Cell Sci (2015) ncbi
rat monoclonal (4E4)
  • western blot; human; 1:1000; fig s5
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in western blot on human samples at 1:1000 (fig s5). Nat Commun (2015) ncbi
rat monoclonal (4E4)
  • western blot; mouse; 1:1000; fig 3
Cell Signaling Technology Rpa2 antibody (cell Signaling Tech, 2208) was used in western blot on mouse samples at 1:1000 (fig 3). Cancer Cell (2015) ncbi
rat monoclonal (4E4)
  • western blot; human; fig 4
Cell Signaling Technology Rpa2 antibody (Cell Signaling, 2208) was used in western blot on human samples (fig 4). Mol Cancer Res (2014) ncbi
rat monoclonal (4E4)
  • immunocytochemistry; human; 1:1000
Cell Signaling Technology Rpa2 antibody (Cell Signaling Technologies, E4A) was used in immunocytochemistry on human samples at 1:1000. Nature (2014) ncbi
Articles Reviewed
  1. Groelly F, Porru M, Zimmer J, Benainous H, De Visser Y, Kosova A, et al. Anti-tumoural activity of the G-quadruplex ligand pyridostatin against BRCA1/2-deficient tumours. EMBO Mol Med. 2022;14:e14501 pubmed publisher
  2. Barger C, Chee L, Albahrani M, Munoz Trujillo C, Boghean L, Branick C, et al. Co-regulation and function of FOXM1/RHNO1 bidirectional genes in cancer. elife. 2021;10: pubmed publisher
  3. Ho K, Luo H, Zhu W, Tang Y. Critical role of SMG7 in activation of the ATR-CHK1 axis in response to genotoxic stress. Sci Rep. 2021;11:7502 pubmed publisher
  4. Shorrocks A, Jones S, Tsukada K, Morrow C, Belblidia Z, Shen J, et al. The Bloom syndrome complex senses RPA-coated single-stranded DNA to restart stalled replication forks. Nat Commun. 2021;12:585 pubmed publisher
  5. Hewitt G, Borel V, Segura Bayona S, Takaki T, Ruis P, Bellelli R, et al. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Mol Cell. 2020;: pubmed publisher
  6. Felipe Medina N, Caburet S, Sánchez Sáez F, Condezo Y, de Rooij D, Gómez H L, et al. A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. elife. 2020;9: pubmed publisher
  7. Brunner A, Suryo Rahmanto A, Johansson H, Franco M, Viiliäinen J, Gazi M, et al. PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. elife. 2020;9: pubmed publisher
  8. Zhang J, Gurusaran M, Fujiwara Y, Zhang K, Echbarthi M, Vorontsov E, et al. The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells. Nat Commun. 2020;11:2055 pubmed publisher
  9. Lo M, Damon L, Wei Tay J, Jia S, Palmer A. Single cell analysis reveals multiple requirements for zinc in the mammalian cell cycle. elife. 2020;9: pubmed publisher
  10. Matsuno Y, Atsumi Y, Shimizu A, Katayama K, Fujimori H, Hyodo M, et al. Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro. Nat Commun. 2019;10:3925 pubmed publisher
  11. Zhang Q, Ji S, Busayavalasa K, Shao J, Yu C. Meiosis I progression in spermatogenesis requires a type of testis-specific 20S core proteasome. Nat Commun. 2019;10:3387 pubmed publisher
  12. Tacconi E, Badie S, De Gregoriis G, Reisländer T, Lai X, Porru M, et al. Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. EMBO Mol Med. 2019;11:e9982 pubmed publisher
  13. Ogawa S, Yamada M, Nakamura A, Sugawara T, Nakamura A, Miyajima S, et al. Zscan5b Deficiency Impairs DNA Damage Response and Causes Chromosomal Aberrations during Mitosis. Stem Cell Reports. 2019;12:1366-1379 pubmed publisher
  14. Fouquerel E, Barnes R, Uttam S, Watkins S, Bruchez M, Opresko P. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Mol Cell. 2019;: pubmed publisher
  15. Aranda S, Alcaine Colet A, Blanco E, Borras E, Caillot C, Sabidó E, et al. Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation. Sci Adv. 2019;5:eaav2448 pubmed publisher
  16. Zhang Q, Ji S, Busayavalasa K, Yu C. SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. Sci Adv. 2019;5:eaau9780 pubmed publisher
  17. Mohni K, Wessel S, Zhao R, Wojciechowski A, Luzwick J, Layden H, et al. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell. 2019;176:144-153.e13 pubmed publisher
  18. Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed publisher
  19. Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  20. Haas K, Lee M, Esposito A, Venkitaraman A. Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites. Nucleic Acids Res. 2018;46:2398-2416 pubmed publisher
  21. Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed publisher
  22. Okazaki A, Gameiro P, Christodoulou D, Laviollette L, Schneider M, Chaves F, et al. Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers. J Clin Invest. 2017;127:1631-1645 pubmed publisher
  23. Smith E, Gole B, Willis N, Soria R, Starnes L, Krumpelbeck E, et al. DEK is required for homologous recombination repair of DNA breaks. Sci Rep. 2017;7:44662 pubmed publisher
  24. Leung J, Makharashvili N, Agarwal P, Chiu L, Pourpre R, Cammarata M, et al. ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair. Genes Dev. 2017;31:260-274 pubmed publisher
  25. Liu Y, Cussiol J, Dibitetto D, Sims J, Twayana S, Weiss R, et al. TOPBP1Dpb11 plays a conserved role in homologous recombination DNA repair through the coordinated recruitment of 53BP1Rad9. J Cell Biol. 2017;216:623-639 pubmed publisher
  26. Xu H, Di Antonio M, McKinney S, Mathew V, Ho B, O Neil N, et al. CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours. Nat Commun. 2017;8:14432 pubmed publisher
  27. Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed publisher
  28. Gong Y, Handa N, Kowalczykowski S, de Lange T. PHF11 promotes DSB resection, ATR signaling, and HR. Genes Dev. 2017;31:46-58 pubmed publisher
  29. Kariolis M, Miao Y, Diep A, Nash S, Olcina M, Jiang D, et al. Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies. J Clin Invest. 2017;127:183-198 pubmed publisher
  30. Kotsantis P, Silva L, Irmscher S, Jones R, Folkes L, Gromak N, et al. Increased global transcription activity as a mechanism of replication stress in cancer. Nat Commun. 2016;7:13087 pubmed publisher
  31. Moreno A, Carrington J, Albergante L, Al Mamun M, Haagensen E, Komseli E, et al. Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells. Proc Natl Acad Sci U S A. 2016;113:E5757-64 pubmed publisher
  32. Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al. p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med. 2016;22:861-8 pubmed publisher
  33. Ahrabi S, Sarkar S, Pfister S, Pirovano G, Higgins G, Porter A, et al. A role for human homologous recombination factors in suppressing microhomology-mediated end joining. Nucleic Acids Res. 2016;44:5743-57 pubmed publisher
  34. Onyango D, Howard S, Neherin K, Yanez D, Stark J. Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. Nucleic Acids Res. 2016;44:5702-16 pubmed publisher
  35. Passerini V, Ozeri Galai E, de Pagter M, Donnelly N, Schmalbrock S, Kloosterman W, et al. The presence of extra chromosomes leads to genomic instability. Nat Commun. 2016;7:10754 pubmed publisher
  36. Ahuja A, Jodkowska K, Teloni F, Bizard A, Zellweger R, Herrador R, et al. A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells. Nat Commun. 2016;7:10660 pubmed publisher
  37. Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed publisher
  38. Choi Y, Meghani K, Brault M, Leclerc L, He Y, Day T, et al. Platinum and PARP Inhibitor Resistance Due to Overexpression of MicroRNA-622 in BRCA1-Mutant Ovarian Cancer. Cell Rep. 2016;14:429-439 pubmed publisher
  39. Zhang H, Liu H, Chen Y, Yang X, Wang P, Liu T, et al. A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice. Nat Commun. 2016;7:10201 pubmed publisher
  40. Baude A, Aaes T, Zhai B, Al Nakouzi N, Oo H, Daugaard M, et al. Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination. Nucleic Acids Res. 2016;44:2214-26 pubmed publisher
  41. Hoffmann S, Smedegaard S, Nakamura K, Mortuza G, Räschle M, Ibañez de Opakua A, et al. TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J Cell Biol. 2016;212:63-75 pubmed publisher
  42. Ceccon M, Merlo M, Mologni L, Poggio T, Varesio L, Menotti M, et al. Excess of NPM-ALK oncogenic signaling promotes cellular apoptosis and drug dependency. Oncogene. 2016;35:3854-3865 pubmed publisher
  43. Sakurikar N, Thompson R, Montano R, Eastman A. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase. Oncotarget. 2016;7:1380-94 pubmed publisher
  44. Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed publisher
  45. Yu Z, Huang Y, Shieh S. Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation. Nucleic Acids Res. 2016;44:1133-50 pubmed publisher
  46. Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed publisher
  47. Xing M, Wang X, Palmai Pallag T, Shen H, Helleday T, Hickson I, et al. Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response. Oncotarget. 2015;6:37638-46 pubmed publisher
  48. Domínguez D, Feijoo P, Bernal A, Ercilla A, Agell N, Genescà A, et al. Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16INK4a deficiency and telomere-dependent genotoxic stress. Oncotarget. 2015;6:28238-56 pubmed publisher
  49. Bravo M, Nicolini F, Starowicz K, Barroso S, Calés C, Aguilera A, et al. Polycomb RING1A- and RING1B-dependent histone H2A monoubiquitylation at pericentromeric regions promotes S-phase progression. J Cell Sci. 2015;128:3660-71 pubmed publisher
  50. Specks J, Lecona E, Lopez Contreras A, Fernandez Capetillo O. A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development. Mol Cell Biol. 2015;35:2910-7 pubmed publisher
  51. Tomas Roca L, Tsaalbi Shtylik A, Jansen J, Singh M, Epstein J, Altunoglu U, et al. De novo mutations in PLXND1 and REV3L cause Möbius syndrome. Nat Commun. 2015;6:7199 pubmed publisher
  52. Selvaraj D, Gangadharan V, Michalski C, Kurejova M, Stösser S, Srivastava K, et al. A Functional Role for VEGFR1 Expressed in Peripheral Sensory Neurons in Cancer Pain. Cancer Cell. 2015;27:780-96 pubmed publisher
  53. Parameswaran B, Chiang H, Lu Y, Coates J, Deng C, Baer R, et al. Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection. Cell Cycle. 2015;14:437-48 pubmed publisher
  54. Howard S, Yanez D, Stark J. DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining. PLoS Genet. 2015;11:e1004943 pubmed publisher
  55. Bursomanno S, Beli P, Khan A, Minocherhomji S, Wagner S, Bekker Jensen S, et al. Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells. DNA Repair (Amst). 2015;25:84-96 pubmed publisher
  56. Xue L, Furusawa Y, Okayasu R, Miura M, Cui X, Liu C, et al. The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function. DNA Repair (Amst). 2015;25:72-83 pubmed publisher
  57. Moskwa P, Zinn P, Choi Y, Shukla S, Fendler W, Chen C, et al. A functional screen identifies miRs that induce radioresistance in glioblastomas. Mol Cancer Res. 2014;12:1767-78 pubmed publisher
  58. Vassileva I, Yanakieva I, Peycheva M, Gospodinov A, Anachkova B. The mammalian INO80 chromatin remodeling complex is required for replication stress recovery. Nucleic Acids Res. 2014;42:9074-86 pubmed publisher
  59. Carvalho S, Vítor A, Sridhara S, Martins F, Raposo A, Desterro J, et al. SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint. elife. 2014;3:e02482 pubmed publisher
  60. Sarbajna S, Davies D, West S. Roles of SLX1-SLX4, MUS81-EME1, and GEN1 in avoiding genome instability and mitotic catastrophe. Genes Dev. 2014;28:1124-36 pubmed publisher
  61. Gad H, Koolmeister T, Jemth A, Eshtad S, Jacques S, Ström C, et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature. 2014;508:215-21 pubmed publisher
  62. Gao M, Wei W, Li M, Wu Y, Ba Z, Jin K, et al. Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination. Cell Res. 2014;24:532-41 pubmed publisher
  63. Wan L, Huang J. The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR). J Biol Chem. 2014;289:6619-26 pubmed publisher
  64. O Sullivan R, Arnoult N, Lackner D, Oganesian L, Haggblom C, Corpet A, et al. Rapid induction of alternative lengthening of telomeres by depletion of the histone chaperone ASF1. Nat Struct Mol Biol. 2014;21:167-74 pubmed publisher
  65. Bee L, Fabris S, Cherubini R, Mognato M, Celotti L. The efficiency of homologous recombination and non-homologous end joining systems in repairing double-strand breaks during cell cycle progression. PLoS ONE. 2013;8:e69061 pubmed publisher
  66. Qin Z, Lu M, Xu X, Hanna M, Shiomi N, Xiao W. DNA-damage tolerance mediated by PCNA*Ub fusions in human cells is dependent on Rev1 but not Polη. Nucleic Acids Res. 2013;41:7356-69 pubmed publisher