This is a Validated Antibody Database (VAD) review about mouse Ripk3, based on 35 published articles (read how Labome selects the articles), using Ripk3 antibody in all methods. It is aimed to help Labome visitors find the most suited Ripk3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ripk3 synonym: 2610528K09Rik; AW107945; Rip3

Knockout validation
Abcam
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot knockout validation; mouse; loading ...; fig 3b
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot knockout validation on mouse samples (fig 3b). Cancer Cell (2018) ncbi
Abcam
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s5c
Abcam Ripk3 antibody (Abcam, ab62344) was used in western blot knockout validation on mouse samples (fig s5c). J Clin Invest (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:2000; fig 5
Novus Biologicals Ripk3 antibody (IMGENEX, IMG-5523) was used in western blot knockout validation on mouse samples at 1:2000 (fig 5). Nat Commun (2016) ncbi
ProSci
domestic rabbit polyclonal
  • western blot; human; fig 1
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
ProSci Ripk3 antibody (ProSci, 2283) was used in western blot on human samples (fig 1), in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry - paraffin section on mouse samples (fig 1). Oncotarget (2016) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c
  • western blot; human; loading ...; fig 1b
Abcam Ripk3 antibody (Abcam, ab62344) was used in immunohistochemistry - paraffin section on human samples at 1:100 (fig 1c) and in western blot on human samples (fig 1b). BMC Gastroenterol (2022) ncbi
domestic rabbit monoclonal (EPR23660-20)
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 6f
  • western blot; mouse; 1:1000; loading ...; fig 7c, 7e
  • immunocytochemistry; human; 1:100; loading ...; fig 4s2c
  • western blot; human; 1:1000; loading ...; fig 3b
Abcam Ripk3 antibody (Abcam, Ab255705) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 6f), in western blot on mouse samples at 1:1000 (fig 7c, 7e), in immunocytochemistry on human samples at 1:100 (fig 4s2c) and in western blot on human samples at 1:1000 (fig 3b). elife (2021) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot; mouse; 1:1000; loading ...; fig 4c
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot on mouse samples at 1:1000 (fig 4c). Stem Cell Reports (2021) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot; mouse; loading ...; fig s2a
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot on mouse samples (fig s2a). Cell Death Dis (2021) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot; human; 1:3000; loading ...
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot on human samples at 1:3000. Cell Death Dis (2020) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • immunohistochemistry - paraffin section; mouse; 1:300; loading ...; fig s3a
Abcam Ripk3 antibody (Abcam, ab195117) was used in immunohistochemistry - paraffin section on mouse samples at 1:300 (fig s3a). Cell Death Dis (2020) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • immunohistochemistry; mouse; 1:100; loading ...; fig s12c
  • western blot; mouse; 1:1000; loading ...; fig s12b
Abcam Ripk3 antibody (Abcam, ab195117) was used in immunohistochemistry on mouse samples at 1:100 (fig s12c) and in western blot on mouse samples at 1:1000 (fig s12b). Nat Commun (2020) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot knockout validation; mouse; loading ...; fig 3b
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot knockout validation on mouse samples (fig 3b). Cancer Cell (2018) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot; mouse; loading ...; fig 6a
Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot on mouse samples (fig 6a). J Cell Biol (2017) ncbi
domestic rabbit monoclonal (EPR9516(N)-25)
  • western blot; mouse; fig 4
In order to elucidate the mechanism by which RIPK1 counteracts RIPK3-MLKL-mediated necroptosis, Abcam Ripk3 antibody (Abcam, ab195117) was used in western blot on mouse samples (fig 4). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; loading ...; fig s5c
Abcam Ripk3 antibody (Abcam, ab62344) was used in western blot knockout validation on mouse samples (fig s5c). J Clin Invest (2016) ncbi
Santa Cruz Biotechnology
mouse monoclonal (B-2)
  • western blot; human; loading ...; fig 2c
Santa Cruz Biotechnology Ripk3 antibody (Santa, sc-374639) was used in western blot on human samples (fig 2c). NPJ Breast Cancer (2021) ncbi
mouse monoclonal (B-2)
  • flow cytometry; human; loading ...; fig 3
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz, sc-374639) was used in flow cytometry on human samples (fig 3). Apoptosis (2020) ncbi
mouse monoclonal (B-2)
  • immunohistochemistry; mouse; 1:50; loading ...; fig 4e
  • western blot; mouse; 1:50; loading ...; fig 6c
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz, sc-374639) was used in immunohistochemistry on mouse samples at 1:50 (fig 4e) and in western blot on mouse samples at 1:50 (fig 6c). Sci Rep (2020) ncbi
mouse monoclonal (B-2)
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 1a
  • western blot; human; 1:1500; loading ...; fig 1c, 2c
  • immunoprecipitation; mouse; 1:300; loading ...; fig s4a
  • western blot; mouse; 1:1500; loading ...; fig 3f
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz, sc-374639) was used in immunohistochemistry - paraffin section on human samples at 1:500 (fig 1a), in western blot on human samples at 1:1500 (fig 1c, 2c), in immunoprecipitation on mouse samples at 1:300 (fig s4a) and in western blot on mouse samples at 1:1500 (fig 3f). Cell Death Dis (2020) ncbi
mouse monoclonal (B-2)
  • western blot; mouse; loading ...; fig 5a
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz Biotechnology, SC?\374639) was used in western blot on mouse samples (fig 5a). Oral Dis (2020) ncbi
mouse monoclonal (B-2)
  • western blot; mouse; 1:1000; loading ...; fig 5b
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz Biotechnology, sc-374639) was used in western blot on mouse samples at 1:1000 (fig 5b). J Cell Sci (2019) ncbi
mouse monoclonal (B-2)
  • western blot; human; fig 1c
Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz, B-2) was used in western blot on human samples (fig 1c). Blood (2017) ncbi
mouse monoclonal (B-2)
  • western blot; human; fig 5
In order to investigate the consequences of genetic or pharmacological inhibition of BMI1, Santa Cruz Biotechnology Ripk3 antibody (Santa Cruz Biotechnology, 374639) was used in western blot on human samples (fig 5). Autophagy (2016) ncbi
mouse monoclonal (B-2)
  • western blot; human; fig 3
Santa Cruz Biotechnology Ripk3 antibody (santa Cruz, sc-374639) was used in western blot on human samples (fig 3). Cell Death Dis (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; loading ...; fig 3b
Novus Biologicals Ripk3 antibody (Novus, NBP1-77299) was used in immunohistochemistry - frozen section on mouse samples (fig 3b). iScience (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 5f
  • western blot; rat; 1:1000; loading ...; fig 2e
Novus Biologicals Ripk3 antibody (Novusbio, NBP1-77299) was used in immunohistochemistry - paraffin section on rat samples at 1:200 (fig 5f) and in western blot on rat samples at 1:1000 (fig 2e). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • proximity ligation assay; human; 1:50; loading ...; fig 1g
  • western blot; human; 1:1000; loading ...; fig 1c
Novus Biologicals Ripk3 antibody (Novus Biological, NBP2-24588) was used in proximity ligation assay on human samples at 1:50 (fig 1g) and in western blot on human samples at 1:1000 (fig 1c). Mol Cell (2019) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig s3g
Novus Biologicals Ripk3 antibody (Novus, NBP1-77299) was used in immunoprecipitation on mouse samples (fig s3g). Nature (2016) ncbi
domestic rabbit polyclonal
  • western blot knockout validation; mouse; 1:2000; fig 5
Novus Biologicals Ripk3 antibody (IMGENEX, IMG-5523) was used in western blot knockout validation on mouse samples at 1:2000 (fig 5). Nat Commun (2016) ncbi
Bio-Rad
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
Bio-Rad Ripk3 antibody (Biorad, AHP1797) was used in western blot on mouse samples (fig 2a). Proc Natl Acad Sci U S A (2017) ncbi
Cell Signaling Technology
domestic rabbit
  • western blot; mouse; loading ...; fig 4b
Cell Signaling Technology Ripk3 antibody (Cell Signaling Technology, 57220) was used in western blot on mouse samples (fig 4b). Front Med (Lausanne) (2021) ncbi
domestic rabbit
  • western blot; mouse; loading ...; fig 5a
Cell Signaling Technology Ripk3 antibody (Cell Signaling Technology, 57220) was used in western blot on mouse samples (fig 5a). Oral Dis (2020) ncbi
domestic rabbit
  • western blot; mouse; 1:1000; loading ...; fig 3a
Cell Signaling Technology Ripk3 antibody (Cell Signaling Technology, 57220) was used in western blot on mouse samples at 1:1000 (fig 3a). J Cell Sci (2019) ncbi
domestic rabbit
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 4e
Cell Signaling Technology Ripk3 antibody (Cell Signaling, 57220) was used in immunohistochemistry - paraffin section on mouse samples (fig 4e). Cell Death Differ (2019) ncbi
ProSci
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6b
ProSci Ripk3 antibody (Prosci, 2283) was used in western blot on mouse samples at 1:1000 (fig 6b). J Pathol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2b
ProSci Ripk3 antibody (ProSci, 2283) was used in western blot on mouse samples (fig 2b). Cell Res (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:6000; loading ...; fig 1a
ProSci Ripk3 antibody (ProSci, 2283) was used in western blot on mouse samples at 1:6000 (fig 1a). Cell Death Dis (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:3000; loading ...; fig 4a
ProSci Ripk3 antibody (ProSci, 2283) was used in western blot on mouse samples at 1:3000 (fig 4a). J Cell Sci (2019) ncbi
domestic rabbit polyclonal
  • proximity ligation assay; mouse; 1:50; loading ...; fig 1f
ProSci Ripk3 antibody (ProSci Inc, 2283) was used in proximity ligation assay on mouse samples at 1:50 (fig 1f). Mol Cell (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2a
ProSci Ripk3 antibody (ProSci Inc., 2283) was used in western blot on mouse samples (fig 2a). Cell Death Differ (2016) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; fig 1
  • western blot; mouse; fig 4
In order to analyze induction of efficient anti-tumor immunity by vaccination with necroptotic cancer cells, ProSci Ripk3 antibody (ProSci, 2283) was used in immunoprecipitation on mouse samples (fig 1) and in western blot on mouse samples (fig 4). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1c
ProSci Ripk3 antibody (Prosci, 2283) was used in western blot on mouse samples (fig 1c). J Biol Chem (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 1
  • western blot knockout validation; mouse; fig 1
  • immunohistochemistry - paraffin section; mouse; fig 1
ProSci Ripk3 antibody (ProSci, 2283) was used in western blot on human samples (fig 1), in western blot knockout validation on mouse samples (fig 1) and in immunohistochemistry - paraffin section on mouse samples (fig 1). Oncotarget (2016) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; 1:4000; loading ...; fig 4h
MilliporeSigma Ripk3 antibody (Sigma, R4277) was used in western blot on mouse samples at 1:4000 (fig 4h). Exp Eye Res (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3c
MilliporeSigma Ripk3 antibody (Sigma, R4277) was used in western blot on mouse samples (fig 3c). Cell Death Differ (2021) ncbi
Articles Reviewed
  1. Duan C, Xu X, Lu X, Wang L, Lu Z. RIP3 knockdown inhibits necroptosis of human intestinal epithelial cells via TLR4/MyD88/NF-κB signaling and ameliorates murine colitis. BMC Gastroenterol. 2022;22:137 pubmed publisher
  2. Sato K, Sato T, Ohno Oishi M, Ozawa M, Maekawa S, Shiga Y, et al. CHOP deletion and anti-neuroinflammation treatment with hesperidin synergistically attenuate NMDA retinal injury in mice. Exp Eye Res. 2021;213:108826 pubmed publisher
  3. Jiao L, Eickhoff R, Egners A, Jumpertz S, Roth J, Erdem M, et al. Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer. J Pathol. 2021;255:270-284 pubmed publisher
  4. Li Y, Li Z, Quan Y, Cheng H, Riquelme M, Li X, et al. Macrophage recruitment in immune-privileged lens during capsule repair, necrotic fiber removal, and fibrosis. iScience. 2021;24:102533 pubmed publisher
  5. Li D, Chen J, Guo J, Li L, Cai G, Chen S, et al. A phosphorylation of RIPK3 kinase initiates an intracellular apoptotic pathway that promotes prostaglandin2α-induced corpus luteum regression. elife. 2021;10: pubmed publisher
  6. Yin Z, Chen W, Yin J, Sun J, Xie Q, Wu M, et al. RIPK1 is a negative mediator in Aquaporin 1-driven triple-negative breast carcinoma progression and metastasis. NPJ Breast Cancer. 2021;7:53 pubmed publisher
  7. Cheng J, Duan X, Fu X, Jiang Y, Yang P, Cao C, et al. RIP1 Perturbation Induces Chondrocyte Necroptosis and Promotes Osteoarthritis Pathogenesis via Targeting BMP7. Front Cell Dev Biol. 2021;9:638382 pubmed publisher
  8. Wang S, Li S, Li Y, Jiang Q, Li X, Wang Y, et al. Non-muscle myosin heavy chain 9 maintains intestinal homeostasis by preventing epithelium necroptosis and colitis adenoma formation. Stem Cell Reports. 2021;16:1290-1301 pubmed publisher
  9. Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed publisher
  10. Moujalled D, Gangatirkar P, Kauppi M, Corbin J, Lebois M, Murphy J, et al. The necroptotic cell death pathway operates in megakaryocytes, but not in platelet synthesis. Cell Death Dis. 2021;12:133 pubmed publisher
  11. Zhou S, Zhang W, Cai G, Ding Y, Wei C, Li S, et al. Myofiber necroptosis promotes muscle stem cell proliferation via releasing Tenascin-C during regeneration. Cell Res. 2020;30:1063-1077 pubmed publisher
  12. Hu H, Wu X, Wu G, Nan N, Zhang J, Zhu X, et al. RIP3-mediated necroptosis is regulated by inter-filament assembly of RIP homotypic interaction motif. Cell Death Differ. 2021;28:251-266 pubmed publisher
  13. Warnes G. Flow cytometric detection of hyper-polarized mitochondria in regulated and accidental cell death processes. Apoptosis. 2020;25:548-557 pubmed publisher
  14. Wu Y, Chou T, Young L, Hsieh F, Pan H, Mo S, et al. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020;11:305 pubmed publisher
  15. Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed publisher
  16. Duan X, Liu X, Liu N, Huang Y, Jin Z, Zhang S, et al. Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation. Cell Death Dis. 2020;11:134 pubmed publisher
  17. Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, et al. YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology. Nat Commun. 2020;11:507 pubmed publisher
  18. Choi S, Shin S, Lee H, Sohn K, Yoon S, Kim J. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositis. Oral Dis. 2020;26:111-121 pubmed publisher
  19. Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
  20. Krishna Subramanian S, Singer S, Armaka M, Banales J, Hölzer K, Schirmacher P, et al. RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ. 2019;: pubmed publisher
  21. Liccardi G, Ramos Garcia L, Tenev T, Annibaldi A, Legrand A, Robertson D, et al. RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol Cell. 2019;73:413-428.e7 pubmed publisher
  22. Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher
  23. Wang H, Meng H, Li X, Zhu K, Dong K, Mookhtiar A, et al. PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP. Proc Natl Acad Sci U S A. 2017;114:11944-11949 pubmed publisher
  24. Hos N, Ganesan R, Gutierrez S, Hos D, Klimek J, Abdullah Z, et al. Type I interferon enhances necroptosis of Salmonella Typhimurium-infected macrophages by impairing antioxidative stress responses. J Cell Biol. 2017;216:4107-4121 pubmed publisher
  25. Greenlee Wacker M, Kremserová S, Nauseef W. Lysis of human neutrophils by community-associated methicillin-resistant Staphylococcus aureus. Blood. 2017;129:3237-3244 pubmed publisher
  26. Newton K, Wickliffe K, Maltzman A, Dugger D, Strasser A, Pham V, et al. RIPK1 inhibits ZBP1-driven necroptosis during development. Nature. 2016;540:129-133 pubmed publisher
  27. Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed publisher
  28. Günther C, He G, Kremer A, Murphy J, Petrie E, Amann K, et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis. J Clin Invest. 2016;126:4346-4360 pubmed publisher
  29. Gautheron J, Vucur M, Schneider A, Severi I, Roderburg C, Roy S, et al. The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance. Nat Commun. 2016;7:11869 pubmed publisher
  30. Shutinoski B, Alturki N, Rijal D, Bertin J, Gough P, Schlossmacher M, et al. K45A mutation of RIPK1 results in poor necroptosis and cytokine signaling in macrophages, which impacts inflammatory responses in vivo. Cell Death Differ. 2016;23:1628-37 pubmed publisher
  31. Aaes T, Kaczmarek A, Delvaeye T, De Craene B, De Koker S, Heyndrickx L, et al. Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity. Cell Rep. 2016;15:274-87 pubmed publisher
  32. Dey A, Mustafi S, Saha S, Kumar Dhar Dwivedi S, Mukherjee P, Bhattacharya R. Inhibition of BMI1 induces autophagy-mediated necroptosis. Autophagy. 2016;12:659-70 pubmed publisher
  33. Zhao X, Chen Z, Zhao J, Zhang P, Pu Y, Jiang S, et al. Hsp90 modulates the stability of MLKL and is required for TNF-induced necroptosis. Cell Death Dis. 2016;7:e2089 pubmed publisher
  34. Moriwaki K, Chan F. Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome. J Biol Chem. 2016;291:5948-59 pubmed publisher
  35. Wang S, Ni H, Dorko K, Kumer S, Schmitt T, Nawabi A, et al. Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury. Oncotarget. 2016;7:17681-98 pubmed publisher