This is a Validated Antibody Database (VAD) review about mouse Rasgrp3, based on 3 published articles (read how Labome selects the articles), using Rasgrp3 antibody in all methods. It is aimed to help Labome visitors find the most suited Rasgrp3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rasgrp3 synonym: BC066069; Gm327; ras guanyl-releasing protein 3

Knockout validation
Cell Signaling Technology
rabbit monoclonal (C33A3)
  • western blot knockout validation; mouse; fig 1
Cell Signaling Technology Rasgrp3 antibody (Cell signaling, 3334) was used in western blot knockout validation on mouse samples (fig 1). Nat Commun (2014) ncbi
Abcam
rabbit monoclonal (EPNCIR148)
  • western blot; human; loading ...; fig 5g
In order to study the effect of GNAQ mutations and GNA11/MAPK pathway activation in uveal melanoma, Abcam Rasgrp3 antibody (Abcam, ab124823) was used in western blot on human samples (fig 5g). Cancer Cell (2017) ncbi
Cell Signaling Technology
rabbit monoclonal (C33A3)
  • western blot; human; loading ...; fig 5a
In order to study the effect of GNAQ mutations and GNA11/MAPK pathway activation in uveal melanoma, Cell Signaling Technology Rasgrp3 antibody (Cell Signaling, 3334) was used in western blot on human samples (fig 5a). Cancer Cell (2017) ncbi
rabbit monoclonal (C33A3)
  • western blot; human; fig 6
Cell Signaling Technology Rasgrp3 antibody (Cell Signaling, 3334) was used in western blot on human samples (fig 6). Sci Rep (2015) ncbi
rabbit monoclonal (C33A3)
  • western blot knockout validation; mouse; fig 1
Cell Signaling Technology Rasgrp3 antibody (Cell signaling, 3334) was used in western blot knockout validation on mouse samples (fig 1). Nat Commun (2014) ncbi
Articles Reviewed
  1. Chen X, Wu Q, Depeille P, Chen P, Thornton S, Kalirai H, et al. RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma. Cancer Cell. 2017;31:685-696.e6 pubmed publisher
  2. Yamagishi M, Katano H, Hishima T, Shimoyama T, Ota Y, Nakano K, et al. Coordinated loss of microRNA group causes defenseless signaling in malignant lymphoma. Sci Rep. 2015;5:17868 pubmed publisher
  3. Tang S, Chen T, Yu Z, Zhu X, Yang M, Xie B, et al. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase. Nat Commun. 2014;5:4657 pubmed publisher