This is a Validated Antibody Database (VAD) review about mouse Rapsn, based on 8 published articles (read how Labome selects the articles), using Rapsn antibody in all methods. It is aimed to help Labome visitors find the most suited Rapsn antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rapsn synonym: 43kDa; Nraps; Raps; rapsyn

Abcam
mouse monoclonal (1234)
  • western blot; mouse; 1:1000; loading ...; fig 1a
Abcam Rapsn antibody (Abcam, ab11423) was used in western blot on mouse samples at 1:1000 (fig 1a). elife (2019) ncbi
domestic rabbit monoclonal (EPR9759)
  • western blot; human; 1:250; loading ...; fig 2b
Abcam Rapsn antibody (Abcam, ab156002) was used in western blot on human samples at 1:250 (fig 2b). J Appl Physiol (1985) (2018) ncbi
mouse monoclonal (1234)
  • immunohistochemistry - frozen section; brown rat; fig 2
In order to discuss the age-related presence of denervated myofibers and accelerated muscle atrophy, Abcam Rapsn antibody (Abcam, Ab11423) was used in immunohistochemistry - frozen section on brown rat samples (fig 2). Skelet Muscle (2016) ncbi
domestic rabbit monoclonal (EPR9759)
  • western blot; mouse; 1:1000; fig 2
In order to show that Rspo2 and Lgr5 are Wnt-dependent and agrin-independent regulators of acetylcholine receptor clustering at the neuromuscular junction, Abcam Rapsn antibody (Abcam, ab156002) was used in western blot on mouse samples at 1:1000 (fig 2). Sci Rep (2016) ncbi
mouse monoclonal (1234)
  • immunohistochemistry; mouse; 1:200; fig 4
Abcam Rapsn antibody (abcam, ab11423) was used in immunohistochemistry on mouse samples at 1:200 (fig 4). Sci Rep (2016) ncbi
mouse monoclonal (1234)
  • immunohistochemistry; mouse; 1:200; fig 6
In order to utilize a system for neuromuscular junction development and maintenance to study mechanisms, Abcam Rapsn antibody (Abcam, ab11423) was used in immunohistochemistry on mouse samples at 1:200 (fig 6). Development (2016) ncbi
MilliporeSigma
mouse monoclonal (1234)
  • immunocytochemistry; mouse; 1:200
  • western blot; mouse; 1:5000
In order to show that rapsyn plays an AChR-independent role in lysosomes organization, MilliporeSigma Rapsn antibody (Sigma, R2029) was used in immunocytochemistry on mouse samples at 1:200 and in western blot on mouse samples at 1:5000. J Cell Sci (2015) ncbi
mouse monoclonal (1234)
  • western blot; mouse
MilliporeSigma Rapsn antibody (Sigma, 1234) was used in western blot on mouse samples . FEBS Lett (2012) ncbi
Articles Reviewed
  1. Xing G, Jing H, Zhang L, Cao Y, Li L, Zhao K, et al. A mechanism in agrin signaling revealed by a prevalent Rapsyn mutation in congenital myasthenic syndrome. elife. 2019;8: pubmed publisher
  2. Kelly N, Hammond K, Bickel C, Windham S, Tuggle S, Bamman M. Effects of aging and Parkinson's disease on motor unit remodeling: influence of resistance exercise training. J Appl Physiol (1985). 2018;124:888-898 pubmed publisher
  3. Aare S, Spendiff S, Vuda M, Elkrief D, Pérez A, Wu Q, et al. Failed reinnervation in aging skeletal muscle. Skelet Muscle. 2016;6:29 pubmed publisher
  4. Nakashima H, Ohkawara B, Ishigaki S, Fukudome T, Ito K, Tsushima M, et al. R-spondin 2 promotes acetylcholine receptor clustering at the neuromuscular junction via Lgr5. Sci Rep. 2016;6:28512 pubmed publisher
  5. Vilmont V, Cadot B, Vezin E, Le Grand F, Gomes E. Dynein disruption perturbs post-synaptic components and contributes to impaired MuSK clustering at the NMJ: implication in ALS. Sci Rep. 2016;6:27804 pubmed publisher
  6. Vilmont V, Cadot B, Ouanounou G, Gomes E. A system for studying mechanisms of neuromuscular junction development and maintenance. Development. 2016;143:2464-77 pubmed publisher
  7. Aittaleb M, Chen P, Akaaboune M. Failure of lysosome clustering and positioning in the juxtanuclear region in cells deficient in rapsyn. J Cell Sci. 2015;128:3744-56 pubmed publisher
  8. Chang Y, Chou H, Yen Y, Chang H, Hong Y, Huang H, et al. Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes. FEBS Lett. 2012;586:3111-6 pubmed publisher