This is a Validated Antibody Database (VAD) review about mouse Rabgef1, based on 4 published articles (read how Labome selects the articles), using Rabgef1 antibody in all methods. It is aimed to help Labome visitors find the most suited Rabgef1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Rabgef1 synonym: Rab5ef; Rabex5; Rin2; rab5 GDP/GTP exchange factor; Rab5 exchange factor; Ras negative regulator Rabex-5; Ras negative regulator Rabex-5/Rin2; rabex-5

Knockout validation
Cell Signaling Technology
rabbit monoclonal (D21F12)
  • western blot knockout validation; human; fig 5
Cell Signaling Technology Rabgef1 antibody (Cell Signaling, 7622) was used in western blot knockout validation on human samples (fig 5). Autophagy (2017) ncbi
Proteintech Group
rabbit polyclonal
  • proximity ligation assay; mouse; fig 2
Proteintech Group Rabgef1 antibody (Proteintech, 12735-1-AP) was used in proximity ligation assay on mouse samples (fig 2). Sci Rep (2016) ncbi
Cell Signaling Technology
rabbit monoclonal (D21F12)
  • western blot; mouse; fig 4F
In order to show that deletion of the gene encoding RAB guanine nucleotide exchange factor 1 in keratinocytes severely impairs epidermal barrier function in mice, Cell Signaling Technology Rabgef1 antibody (Cell signaling, D21F12) was used in western blot on mouse samples (fig 4F). J Clin Invest (2016) ncbi
rabbit monoclonal (D21F12)
  • western blot knockout validation; human; fig 5
Cell Signaling Technology Rabgef1 antibody (Cell Signaling, 7622) was used in western blot knockout validation on human samples (fig 5). Autophagy (2017) ncbi
Sigma-Aldrich
rabbit polyclonal
  • western blot; human; loading ...; fig s1b
  • immunocytochemistry; mouse; loading ...; fig s5a
In order to explore how cereblon modulates the efficacy of immunomodulatory drugs, Sigma-Aldrich Rabgef1 antibody (Sigma, 5405) was used in western blot on human samples (fig s1b) and in immunocytochemistry on mouse samples (fig s5a). Proc Natl Acad Sci U S A (2016) ncbi
Articles Reviewed
  1. Marichal T, Gaudenzio N, El Abbas S, Sibilano R, Zurek O, Starkl P, et al. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis. J Clin Invest. 2016;126:4497-4515 pubmed publisher
  2. Nozawa T, Minowa Nozawa A, Aikawa C, Nakagawa I. The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. Autophagy. 2017;13:57-69 pubmed publisher
  3. Millrine D, Tei M, Gemechu Y, Kishimoto T. Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production. Proc Natl Acad Sci U S A. 2016;113:10625-30 pubmed publisher
  4. Candiello E, Kratzke M, Wenzel D, Cassel D, Schu P. AP-1/?1A and AP-1/?1B adaptor-proteins differentially regulate neuronal early endosome maturation via the Rab5/Vps34-pathway. Sci Rep. 2016;6:29950 pubmed publisher