This is a Validated Antibody Database (VAD) review about mouse Psenen, based on 6 published articles (read how Labome selects the articles), using Psenen antibody in all methods. It is aimed to help Labome visitors find the most suited Psenen antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Psenen synonym: 1700023M09Rik; Pen-2

Abcam
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1b
Abcam Psenen antibody (Abcam, ab18189) was used in western blot on mouse samples at 1:1000 (fig 1b). elife (2020) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D6G8)
  • western blot; human; 1:1000; fig s7f
Cell Signaling Technology Psenen antibody (Cell Signaling, 8598) was used in western blot on human samples at 1:1000 (fig s7f). Signal Transduct Target Ther (2021) ncbi
domestic rabbit monoclonal (D2G6)
  • western blot; mouse; 1:1000; loading ...; fig s3g
Cell Signaling Technology Psenen antibody (Cell Signaling Technology, 8502) was used in western blot on mouse samples at 1:1000 (fig s3g). J Clin Invest (2019) ncbi
domestic rabbit monoclonal (D6G8)
  • western blot; human; fig s2
Cell Signaling Technology Psenen antibody (Cell Signaling Tech, 8598) was used in western blot on human samples (fig s2). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D2G6)
  • western blot; mouse; fig 3c
In order to assess the efficiency and potential safety of miRNA replacement therapy for Alzheimer's disease, Cell Signaling Technology Psenen antibody (Cell Signaling, 8502) was used in western blot on mouse samples (fig 3c). Mol Ther Nucleic Acids (2015) ncbi
domestic rabbit monoclonal (D2G6)
  • western blot; human
In order to investigate presenilin assembly and catalytic activity, Cell Signaling Technology Psenen antibody (Cell Signaling, D2G6) was used in western blot on human samples . J Biol Chem (2015) ncbi
Articles Reviewed
  1. Luo R, Fan Y, Yang J, Ye M, Zhang D, Guo K, et al. A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. Signal Transduct Target Ther. 2021;6:325 pubmed publisher
  2. Escamilla Ayala A, Sannerud R, Mondin M, Poersch K, Vermeire W, Paparelli L, et al. Super-resolution microscopy reveals majorly mono- and dimeric presenilin1/γ-secretase at the cell surface. elife. 2020;9: pubmed publisher
  3. Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. J Clin Invest. 2019;129:820-833 pubmed publisher
  4. Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher
  5. Parsi S, Smith P, Goupil C, Dorval V, Hébert S. Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease. Mol Ther Nucleic Acids. 2015;4:e256 pubmed publisher
  6. Marinangeli C, Tasiaux B, Opsomer R, Hage S, Sodero A, Dewachter I, et al. Presenilin transmembrane domain 8 conserved AXXXAXXXG motifs are required for the activity of the γ-secretase complex. J Biol Chem. 2015;290:7169-84 pubmed publisher