This is a Validated Antibody Database (VAD) review about mouse Prnp, based on 8 published articles (read how Labome selects the articles), using Prnp antibody in all methods. It is aimed to help Labome visitors find the most suited Prnp antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Prnp synonym: AA960666; AI325101; CD230; PrP; PrP; PrPC; PrPSc; Prn-i; Prn-p; Sinc; prP27-30; prP33-35C

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3a
Abcam Prnp antibody (Abcam, ab3531) was used in western blot on mouse samples (fig 3a). Int J Mol Sci (2020) ncbi
mouse monoclonal (8H4)
  • immunohistochemistry - free floating section; mouse; 1:1000; loading ...; fig 1e
Abcam Prnp antibody (Abcam, ab61409) was used in immunohistochemistry - free floating section on mouse samples at 1:1000 (fig 1e). J Neurosci (2017) ncbi
domestic rabbit monoclonal (EP1802Y)
  • western blot; human; 1:500; loading ...; fig 2e
Abcam Prnp antibody (Abcam, ab52604) was used in western blot on human samples at 1:500 (fig 2e). Sci Rep (2017) ncbi
domestic rabbit monoclonal (EP1802Y)
  • western blot; human; 1:5000
Abcam Prnp antibody (Abcam, ab52604) was used in western blot on human samples at 1:5000. Biochim Biophys Acta (2014) ncbi
Santa Cruz Biotechnology
mouse monoclonal (6D11)
  • immunohistochemistry - paraffin section; mouse; fig 5
  • western blot; mouse; fig 3
Santa Cruz Biotechnology Prnp antibody (Santa Cruz, sc-58581) was used in immunohistochemistry - paraffin section on mouse samples (fig 5) and in western blot on mouse samples (fig 3). Int J Mol Med (2016) ncbi
mouse monoclonal (6D11)
  • immunohistochemistry - paraffin section; mouse; 1:100
In order to investigate the spread of neuronal pathology, Santa Cruz Biotechnology Prnp antibody (Santa Cruz, 6D11) was used in immunohistochemistry - paraffin section on mouse samples at 1:100. Neuropathol Appl Neurobiol (2015) ncbi
mouse monoclonal (6D11)
  • other; mouse; 1:50; loading ...; fig 2a
Santa Cruz Biotechnology Prnp antibody (Santa Cruz, sc-58581) was used in other on mouse samples at 1:50 (fig 2a). Cell Death Differ (2015) ncbi
mouse monoclonal (6D11)
  • immunocytochemistry; hamsters; 1:100
  • western blot; hamsters
Santa Cruz Biotechnology Prnp antibody (SantaCruz, sc-58581) was used in immunocytochemistry on hamsters samples at 1:100 and in western blot on hamsters samples . J Mol Neurosci (2015) ncbi
Articles Reviewed
  1. Makarava N, Chang J, Baskakov I. Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism. Int J Mol Sci. 2020;21: pubmed publisher
  2. Salazar S, Gallardo C, Kaufman A, Herber C, Haas L, Robinson S, et al. Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. J Neurosci. 2017;37:9207-9221 pubmed publisher
  3. Déry M, LeBlanc A. Luman contributes to brefeldin A-induced prion protein gene expression by interacting with the ERSE26 element. Sci Rep. 2017;7:42285 pubmed publisher
  4. Xiao K, Zhang B, Zhang X, Wang J, Chen C, Chen L, et al. Re-infection of the prion from the scrapie‑infected cell line SMB-S15 in three strains of mice, CD1, C57BL/6 and Balb/c. Int J Mol Med. 2016;37:716-26 pubmed publisher
  5. Reis R, Hennessy E, Murray C, Griffin Ã, Cunningham C. At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei. Neuropathol Appl Neurobiol. 2015;41:780-97 pubmed publisher
  6. Woo J, Zhao X, Khan H, Penn C, Wang X, Joly Amado A, et al. Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ. 2015;22:921-34 pubmed publisher
  7. Wang J, Zhang J, Shi Q, Zhang B, Chen C, Chen L, et al. Scrapie infection in experimental rodents and SMB-S15 cells decreased the brain endogenous levels and activities of Sirt1. J Mol Neurosci. 2015;55:1022-30 pubmed publisher
  8. Feng B, Wang Z, Liu T, Jin R, Wang S, Wang W, et al. Methionine oxidation accelerates the aggregation and enhances the neurotoxicity of the D178N variant of the human prion protein. Biochim Biophys Acta. 2014;1842:2345-56 pubmed publisher