This is a Validated Antibody Database (VAD) review about mouse Ppargc1a, based on 42 published articles (read how Labome selects the articles), using Ppargc1a antibody in all methods. It is aimed to help Labome visitors find the most suited Ppargc1a antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Ppargc1a synonym: A830037N07Rik; Gm11133; PGC-1; PPARGC-1-alpha; Pgc-1alpha; Pgc1; Pgco1; Ppargc1

Abcam
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4e, 4f, 4g
Abcam Ppargc1a antibody (Abcam, ab191838) was used in western blot on mouse samples (fig 4e, 4f, 4g). Nat Commun (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8a
  • western blot; mouse; 1:1000; loading ...; fig 8b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8a) and in western blot on mouse samples at 1:1000 (fig 8b). Mol Med Rep (2022) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:1000
Abcam Ppargc1a antibody (Abcam, ab54481) was used in immunocytochemistry on human samples at 1:1000. Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; 1:750; loading ...; fig 7b
Abcam Ppargc1a antibody (Abcam, ab191838) was used in immunohistochemistry - paraffin section on human samples at 1:750 (fig 7b). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • immunoprecipitation; mouse; loading ...; fig 3d
  • western blot; mouse; 1:500-1:2000; loading ...; fig 3b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in immunoprecipitation on mouse samples (fig 3d) and in western blot on mouse samples at 1:500-1:2000 (fig 3b). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000. BMC Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig s3b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig s3b). J Cachexia Sarcopenia Muscle (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 2b, 2g
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig 2b, 2g). Redox Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:100; loading ...; fig 4g
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:100 (fig 4g). J Exp Med (2021) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human; loading ...; fig s1f
Abcam Ppargc1a antibody (Abcam, ab54481) was used in immunohistochemistry - paraffin section on human samples (fig s1f). Sci Rep (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:50; loading ...; fig 3d
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:50 (fig 3d). J Endocrinol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3c
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig 3c). Aging Cell (2021) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 2k
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on human samples (fig 2k). Oncogene (2021) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:300
Abcam Ppargc1a antibody (Abcam, ab54481) was used in immunocytochemistry on human samples at 1:300. Acta Neuropathol (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1a
Abcam Ppargc1a antibody (Abcam, ab191838) was used in western blot on mouse samples at 1:1000 (fig 1a). J Transl Med (2020) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 3d
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on rat samples (fig 3d). J Cachexia Sarcopenia Muscle (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4d
Abcam Ppargc1a antibody (Abcam, Ab54481) was used in western blot on mouse samples (fig 4d). Sci Adv (2019) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig 3b). Sci Total Environ (2019) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 4d
Abcam Ppargc1a antibody (Abcam, Ab54481) was used in western blot on human samples (fig 4d). Br J Pharmacol (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on human samples at 1:1000 (fig 3b). PLoS ONE (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1a
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on human samples (fig 1a). Oncol Lett (2018) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 1f
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig 1f). Nat Commun (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; 1:1000; loading ...; fig 3b
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on human samples at 1:1000 (fig 3b). Stem Cells Int (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 4
Abcam Ppargc1a antibody (Abcam, Ab72230) was used in western blot on mouse samples (fig 4). Physiol Rep (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 2d
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples (fig 2d). J Inflamm (Lond) (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:10,000; loading ...; fig 6B
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:10,000 (fig 6B). PLoS ONE (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3g
Abcam Ppargc1a antibody (Abcam, ab72230) was used in western blot on mouse samples (fig 3g). Cell Death Dis (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5a
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples (fig 5a). Int J Mol Med (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; fig 6d
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:2000 (fig 6d). Nat Commun (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5f
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples (fig 5f). Stem Cells Int (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig S7
In order to research mitochondrial-targeted catalase good for the old mouse proteome but not the young which may function as a reverse antagonistic pleiotropy, Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples at 1:1000 (fig S7). Aging Cell (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2
Abcam Ppargc1a antibody (Abcam, ab72230) was used in western blot on mouse samples at 1:1000 (fig 2). Oxid Med Cell Longev (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 4
Abcam Ppargc1a antibody (abcam, ab54481) was used in western blot on rat samples (fig 4). Int J Mol Sci (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1000; fig 6a
In order to analyze FNDC5, produced in the stomach, and its role in body composition, Abcam Ppargc1a antibody (Abcam, ab191838) was used in western blot on rat samples at 1:1000 (fig 6a). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 5
Abcam Ppargc1a antibody (Abcam, ab72230) was used in western blot on mouse samples (fig 5). Mol Metab (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; fig 6
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on mouse samples (fig 6). Sci Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; human; fig 5
Abcam Ppargc1a antibody (Abcam, ab54481) was used in western blot on human samples (fig 5). Cell Rep (2016) ncbi
domestic rabbit polyclonal
  • western blot; rat; 1:1500; loading ...; fig 4b
Abcam Ppargc1a antibody (Abcam, ab-54481) was used in western blot on rat samples at 1:1500 (fig 4b). Mol Med Rep (2016) ncbi
Novus Biologicals
domestic rabbit polyclonal
  • immunohistochemistry; human; 1:1000; fig 4a
Novus Biologicals Ppargc1a antibody (Novus, NBP1-04676) was used in immunohistochemistry on human samples at 1:1000 (fig 4a). Oncogene (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:3000; loading ...; fig 7a
Novus Biologicals Ppargc1a antibody (Novus Biologicals, NBP1-04676) was used in western blot on mouse samples at 1:3000 (fig 7a). Nat Commun (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 3d
  • western blot; human; 1:1000; loading ...; fig 6d
Invitrogen Ppargc1a antibody (Thermo Fisher, PA5-72948) was used in western blot on mouse samples at 1:1000 (fig 3d) and in western blot on human samples at 1:1000 (fig 6d). Nat Metab (2021) ncbi
Abnova
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 3d
Abnova Ppargc1a antibody (Abnova, PAB12061) was used in western blot on mouse samples (fig 3d). Autophagy (2019) ncbi
MilliporeSigma
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5e
In order to explore the links between oxidative perturbations and plasma albumin modifications in the liver, MilliporeSigma Ppargc1a antibody (Sigma, AV40129) was used in western blot on mouse samples at 1:1000 (fig 5e). Free Radic Biol Med (2017) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 5d
MilliporeSigma Ppargc1a antibody (Sigma, SAB4200209) was used in western blot on mouse samples (fig 5d). Am J Physiol Endocrinol Metab (2016) ncbi
Articles Reviewed
  1. Moore T, Cheng L, Wolf D, Ngo J, Segawa M, Zhu X, et al. Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes. Nat Commun. 2022;13:6661 pubmed publisher
  2. Yeh C, Liu H, Lee M, Leu Y, Chiang W, Chang H, et al. Phytochemical‑rich herbal formula ATG‑125 protects against sucrose‑induced gastrocnemius muscle atrophy by rescuing Akt signaling and improving mitochondrial dysfunction in young adult mice. Mol Med Rep. 2022;25: pubmed publisher
  3. Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed publisher
  4. Chiang S, Braidy N, Maleki S, Lal S, Richardson D, Huang M. Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation. Redox Biol. 2021;46:102038 pubmed publisher
  5. Vieira Lara M, Dommerholt M, Zhang W, Blankestijn M, Wolters J, Abegaz F, et al. Age-related susceptibility to insulin resistance arises from a combination of CPT1B decline and lipid overload. BMC Biol. 2021;19:154 pubmed publisher
  6. Liu H, Zang P, Lee I, Anderson B, Christiani A, Strait Bodey L, et al. Growth hormone secretagogue receptor-1a mediates ghrelin's effects on attenuating tumour-induced loss of muscle strength but not muscle mass. J Cachexia Sarcopenia Muscle. 2021;12:1280-1295 pubmed publisher
  7. Mu W, Qian S, Song Y, Yang L, Song S, Yang Q, et al. BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021;43:101979 pubmed publisher
  8. Rupert J, Narasimhan A, Jengelley D, Jiang Y, Liu J, Au E, et al. Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia. J Exp Med. 2021;218: pubmed publisher
  9. Hsiao Y, Shimizu I, Wakasugi T, Yoshida Y, Ikegami R, Hayashi Y, et al. Cardiac mitofusin-1 is reduced in non-responding patients with idiopathic dilated cardiomyopathy. Sci Rep. 2021;11:6722 pubmed publisher
  10. Miao Y, Qin H, Zhong Y, Huang K, Rao C. Novel adipokine asprosin modulates browning and adipogenesis in white adipose tissue. J Endocrinol. 2021;249:83-93 pubmed publisher
  11. Habtemichael E, Li D, Camporez J, Westergaard X, Sales C, Liu X, et al. Insulin-stimulated endoproteolytic TUG cleavage links energy expenditure with glucose uptake. Nat Metab. 2021;3:378-393 pubmed publisher
  12. Wallace M, Aguirre N, Marcotte G, Marshall A, Baehr L, Hughes D, et al. The ketogenic diet preserves skeletal muscle with aging in mice. Aging Cell. 2021;20:e13322 pubmed publisher
  13. Galbraith L, Mui E, Nixon C, Hedley A, Strachan D, Mackay G, et al. PPAR-gamma induced AKT3 expression increases levels of mitochondrial biogenesis driving prostate cancer. Oncogene. 2021;40:2355-2366 pubmed publisher
  14. Choi G, Lee H, Chae C, Cho J, Jung Y, Kim J, et al. BNIP3L/NIX-mediated mitophagy protects against glucocorticoid-induced synapse defects. Nat Commun. 2021;12:487 pubmed publisher
  15. Mehta A, Gregory J, Dando O, Carter R, Burr K, Nanda J, et al. Mitochondrial bioenergetic deficits in C9orf72 amyotrophic lateral sclerosis motor neurons cause dysfunctional axonal homeostasis. Acta Neuropathol. 2021;141:257-279 pubmed publisher
  16. Gao Y, Dai X, Li Y, Li G, Lin X, Ai C, et al. Role of Parkin-mediated mitophagy in the protective effect of polydatin in sepsis-induced acute kidney injury. J Transl Med. 2020;18:114 pubmed publisher
  17. Shah D, Nisr R, Stretton C, Krasteva Christ G, Hundal H. Caveolin-3 deficiency associated with the dystrophy P104L mutation impairs skeletal muscle mitochondrial form and function. J Cachexia Sarcopenia Muscle. 2020;11:838-858 pubmed publisher
  18. Ghosh A, Bhattacharjee S, Chowdhuri S, Mallick A, Rehman I, Basu S, et al. SCAN1-TDP1 trapping on mitochondrial DNA promotes mitochondrial dysfunction and mitophagy. Sci Adv. 2019;5:eaax9778 pubmed publisher
  19. Wang S, Ni H, Chao X, Wang H, Bridges B, Kumer S, et al. Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis. Autophagy. 2019;15:1954-1969 pubmed publisher
  20. Zuo Z, Liu Z, Gao T, Yin Y, Wang Z, Hou Y, et al. Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice. Sci Total Environ. 2019;668:310-317 pubmed publisher
  21. Zhang C, Deng J, Liu D, Tuo X, Xiao L, Lai B, et al. Nuciferine ameliorates hepatic steatosis in high-fat diet/streptozocin-induced diabetic mice through a PPARα/PPARγ coactivator-1α pathway. Br J Pharmacol. 2018;175:4218-4228 pubmed publisher
  22. Vargas D, Lopez C, Acero E, Benítez E, Wintaco A, Camacho J, et al. Thermogenic capacity of human periaortic adipose tissue is transformed by body weight. PLoS ONE. 2018;13:e0194269 pubmed publisher
  23. Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, et al. Detachment from the primary site and suspension in ascites as the initial step in metabolic reprogramming and metastasis to the omentum in ovarian cancer. Oncol Lett. 2018;15:1357-1361 pubmed publisher
  24. Velázquez Villegas L, Perino A, Lemos V, Zietak M, Nomura M, Pols T, et al. TGR5 signalling promotes mitochondrial fission and beige remodelling of white adipose tissue. Nat Commun. 2018;9:245 pubmed publisher
  25. Lizcano F, Vargas D, Gomez A, Torrado A. Human ADMC-Derived Adipocyte Thermogenic Capacity Is Regulated by IL-4 Receptor. Stem Cells Int. 2017;2017:2767916 pubmed publisher
  26. Guilford B, Parson J, Grote C, Vick S, Ryals J, Wright D. Increased FNDC5 is associated with insulin resistance in high fat-fed mice. Physiol Rep. 2017;5: pubmed publisher
  27. Le N, Kim C, Tu T, Kim B, Park T, Park J, et al. Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle. J Inflamm (Lond). 2017;14:9 pubmed publisher
  28. Kodo K, Sugimoto S, Nakajima H, Mori J, Itoh I, Fukuhara S, et al. Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice. PLoS ONE. 2017;12:e0173661 pubmed publisher
  29. Patche J, Girard D, Catan A, Boyer F, Dobi A, Planesse C, et al. Diabetes-induced hepatic oxidative stress: a new pathogenic role for glycated albumin. Free Radic Biol Med. 2017;102:133-148 pubmed publisher
  30. Liu Z, Gan L, Wu T, Feng F, Luo D, Gu H, et al. Adiponectin reduces ER stress-induced apoptosis through PPARα transcriptional regulation of ATF2 in mouse adipose. Cell Death Dis. 2016;7:e2487 pubmed publisher
  31. Kong Q, Zhang H, Zhao T, Zhang W, Yan M, Dong X, et al. Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice. Int J Mol Med. 2016;38:1715-1726 pubmed publisher
  32. Doan K, Kinyua A, Yang D, Ko C, Moh S, Shong K, et al. FoxO1 in dopaminergic neurons regulates energy homeostasis and targets tyrosine hydroxylase. Nat Commun. 2016;7:12733 pubmed publisher
  33. Zhang C, Weng Y, Shi F, Jin W. The Engrailed-1 Gene Stimulates Brown Adipogenesis. Stem Cells Int. 2016;2016:7369491 pubmed publisher
  34. Stephenson E, Ragauskas A, Jaligama S, Redd J, Parvathareddy J, Peloquin M, et al. Exposure to environmentally persistent free radicals during gestation lowers energy expenditure and impairs skeletal muscle mitochondrial function in adult mice. Am J Physiol Endocrinol Metab. 2016;310:E1003-15 pubmed publisher
  35. Basisty N, Dai D, Gagnidze A, Gitari L, Fredrickson J, Maina Y, et al. Mitochondrial-targeted catalase is good for the old mouse proteome, but not for the young: 'reverse' antagonistic pleiotropy?. Aging Cell. 2016;15:634-45 pubmed publisher
  36. Chen Y, Pandiri I, Joe Y, Kim H, Kim S, Park J, et al. Synergistic Effects of Cilostazol and Probucol on ER Stress-Induced Hepatic Steatosis via Heme Oxygenase-1-Dependent Activation of Mitochondrial Biogenesis. Oxid Med Cell Longev. 2016;2016:3949813 pubmed publisher
  37. Huang Y, Chen C, Tang K, Sheen J, Tiao M, Tain Y, et al. Postnatal High-Fat Diet Increases Liver Steatosis and Apoptosis Threatened by Prenatal Dexamethasone through the Oxidative Effect. Int J Mol Sci. 2016;17:369 pubmed publisher
  38. Barja Fernández S, Folgueira C, Castelao C, Al Massadi O, Bravo S, Garcia Caballero T, et al. FNDC5 is produced in the stomach and associated to body composition. Sci Rep. 2016;6:23067 pubmed publisher
  39. Ost M, Coleman V, Voigt A, van Schothorst E, Keipert S, van der Stelt I, et al. Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action. Mol Metab. 2016;5:79-90 pubmed publisher
  40. Liu Z, Gan L, Chen Y, Luo D, Zhang Z, Cao W, et al. Mark4 promotes oxidative stress and inflammation via binding to PPARγ and activating NF-κB pathway in mice adipocytes. Sci Rep. 2016;6:21382 pubmed publisher
  41. Audet Walsh Ã, Papadopoli D, Gravel S, Yee T, Bridon G, Caron M, et al. The PGC-1α/ERRα Axis Represses One-Carbon Metabolism and Promotes Sensitivity to Anti-folate Therapy in Breast Cancer. Cell Rep. 2016;14:920-931 pubmed publisher
  42. Zhang H, Wang X, Wu Z, Liu H, Chen W, Zhang Z, et al. Beneficial effect of farnesoid X receptor activation on metabolism in a diabetic rat model. Mol Med Rep. 2016;13:2135-42 pubmed publisher