This is a Validated Antibody Database (VAD) review about mouse Plp1, based on 13 published articles (read how Labome selects the articles), using Plp1 antibody in all methods. It is aimed to help Labome visitors find the most suited Plp1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Plp1 synonym: DM20; Plp; jimpy; jp; msd; rsh

Abcam
domestic rabbit monoclonal (EPR23504-106)
  • western blot; mouse; 1:1000; loading ...; fig 3a
Abcam Plp1 antibody (Abcam, ab254363) was used in western blot on mouse samples at 1:1000 (fig 3a). Proc Natl Acad Sci U S A (2022) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; pigs ; 1:500; loading ...; fig 3f, 3g, 3h
Abcam Plp1 antibody (Abcam, ab28486) was used in immunohistochemistry - paraffin section on pigs samples at 1:500 (fig 3f, 3g, 3h). PLoS ONE (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:2000; loading ...; fig 4c
Abcam Plp1 antibody (Abcam, ab28486) was used in western blot on mouse samples at 1:2000 (fig 4c). elife (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 1a
Abcam Plp1 antibody (Abcam, ab28486) was used in western blot on mouse samples (fig 1a). Sci Transl Med (2018) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; rat; 1:500; loading ...; tbl 2
  • western blot; rat; 1:500; loading ...; tbl 2
In order to test if interleukin-1b derived from microglia affects myelination and axon development in lipopolysaccharide-treated cells, Abcam Plp1 antibody (Abcam, ab28486) was used in immunohistochemistry on rat samples at 1:500 (tbl 2) and in western blot on rat samples at 1:500 (tbl 2). J Neuroinflammation (2017) ncbi
domestic rabbit monoclonal (EPR12675(2)(B))
  • immunohistochemistry - paraffin section; mouse; 1:2000; loading ...; fig st11
  • immunohistochemistry - paraffin section; rat; 1:2000; loading ...; fig st11
In order to outline the protocols for antibodies used for immunohistochemical studies, Abcam Plp1 antibody (Abcam, ab183493) was used in immunohistochemistry - paraffin section on mouse samples at 1:2000 (fig st11) and in immunohistochemistry - paraffin section on rat samples at 1:2000 (fig st11). J Toxicol Pathol (2017) ncbi
mouse monoclonal (plpc 1)
  • western blot; mouse; 1:1000
Abcam Plp1 antibody (Abcam, ab9311) was used in western blot on mouse samples at 1:1000. J Neurochem (2013) ncbi
mouse monoclonal (plpc 1)
  • western blot; mouse; 1:2000
Abcam Plp1 antibody (Abcam, ab9311) was used in western blot on mouse samples at 1:2000. Neurobiol Dis (2013) ncbi
Invitrogen
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; fig 2
  • western blot; human; 1:1000; fig 1
In order to examine the contribution of oligodendrocytes to chronic pain pathogenesis, Invitrogen Plp1 antibody (Thermo, PA3-150) was used in western blot on mouse samples at 1:1000 (fig 2) and in western blot on human samples at 1:1000 (fig 1). Mol Pain (2016) ncbi
domestic rabbit polyclonal
In order to elucidate the mechanism by which epsilon-toxin causes white matter damage, Invitrogen Plp1 antibody (Thermo Scientific, PA3151) was used . MBio (2015) ncbi
Santa Cruz Biotechnology
mouse monoclonal (plpc 1)
  • immunohistochemistry - paraffin section; crab eating macaque; 1:100
Santa Cruz Biotechnology Plp1 antibody (Santa Cruz, Sc-58571) was used in immunohistochemistry - paraffin section on crab eating macaque samples at 1:100. J Neuroimmune Pharmacol (2013) ncbi
Aves Labs
  • other; mouse; 1:100; fig 8f
Aves Labs Plp1 antibody (AVES, PLP) was used in other on mouse samples at 1:100 (fig 8f). elife (2016) ncbi
  • western blot; mouse; 1:1000; fig s4
Aves Labs Plp1 antibody (Aves Labs, PLP) was used in western blot on mouse samples at 1:1000 (fig s4). Nat Commun (2014) ncbi
Articles Reviewed
  1. Guo J, Guo Z, Huang Y, Ma S, Yan B, Pan C, et al. Blockage of MLKL prevents myelin damage in experimental diabetic neuropathy. Proc Natl Acad Sci U S A. 2022;119:e2121552119 pubmed publisher
  2. Swier V, White K, Meyerholz D, Chefdeville A, Khanna R, Sieren J, et al. Validating indicators of CNS disorders in a swine model of neurological disease. PLoS ONE. 2020;15:e0228222 pubmed publisher
  3. Zhou L, Shao C, Xie Y, Wang N, Xu S, Luo B, et al. Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination. elife. 2020;9: pubmed publisher
  4. Ou Yang M, Kurz J, Nomura T, Popovic J, Rajapaksha T, Dong H, et al. Axonal organization defects in the hippocampus of adult conditional BACE1 knockout mice. Sci Transl Med. 2018;10: pubmed publisher
  5. Han Q, Lin Q, Huang P, Chen M, Hu X, Fu H, et al. Microglia-derived IL-1? contributes to axon development disorders and synaptic deficit through p38-MAPK signal pathway in septic neonatal rats. J Neuroinflammation. 2017;14:52 pubmed publisher
  6. Furukawa S, Nagaike M, Ozaki K. Databases for technical aspects of immunohistochemistry. J Toxicol Pathol. 2017;30:79-107 pubmed publisher
  7. Micheva K, Wolman D, Mensh B, Pax E, Buchanan J, Smith S, et al. A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons. elife. 2016;5: pubmed publisher
  8. Shi Y, Shu J, Liang Z, Yuan S, Tang S. EXPRESS: Oligodendrocytes in HIV-associated pain pathogenesis. Mol Pain. 2016;12: pubmed publisher
  9. Linden J, Ma Y, Zhao B, Harris J, Rumah K, Schaeren Wiemers N, et al. Clostridium perfringens Epsilon Toxin Causes Selective Death of Mature Oligodendrocytes and Central Nervous System Demyelination. MBio. 2015;6:e02513 pubmed publisher
  10. Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
  11. Haanstra K, Jagessar S, Bauchet A, Doussau M, Fovet C, Heijmans N, et al. Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant in three non-human primate species. J Neuroimmune Pharmacol. 2013;8:1251-64 pubmed publisher
  12. Pereira G, Meng F, Kockara N, Yang B, Wight P. Targeted deletion of the antisilencer/enhancer (ASE) element from intron 1 of the myelin proteolipid protein gene (Plp1) in mouse reveals that the element is dispensable for Plp1 expression in brain during development and remyelination. J Neurochem. 2013;124:454-65 pubmed publisher
  13. Koch S, Scifo E, Rokka A, Trippner P, Lindfors M, Korhonen R, et al. Cathepsin D deficiency induces cytoskeletal changes and affects cell migration pathways in the brain. Neurobiol Dis. 2013;50:107-19 pubmed publisher