This is a Validated Antibody Database (VAD) review about mouse Pkn1, based on 10 published articles (read how Labome selects the articles), using Pkn1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pkn1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pkn1 synonym: DBK; F730027O18Rik; PAK1; PRK1; Pkn; Prkcl1; Stk3

Knockout validation
BD Biosciences
mouse monoclonal (49/PRK1)
  • western blot knockout validation; mouse; loading ...; fig 2a
BD Biosciences Pkn1 antibody (BD Transduction, 610687) was used in western blot knockout validation on mouse samples (fig 2a). Front Synaptic Neurosci (2021) ncbi
Santa Cruz Biotechnology
mouse monoclonal (H-4)
  • western blot; mouse; loading ...; fig 2b
In order to develop and examine a mouse model of chronic di-n-butyl phthalate exposure, Santa Cruz Biotechnology Pkn1 antibody (SantaCruz, sc-393344) was used in western blot on mouse samples (fig 2b). Food Chem Toxicol (2017) ncbi
mouse monoclonal (49)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Pkn1 antibody (Santa Cruz Biotechnology, sc-136037) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
mouse monoclonal (H-4)
  • western blot; mouse; loading ...; fig 3b
Santa Cruz Biotechnology Pkn1 antibody (Santa Cruz, sc-393344) was used in western blot on mouse samples (fig 3b). Nat Immunol (2016) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:500; loading ...; fig 2
Abcam Pkn1 antibody (Abcam, ab231038) was used in western blot on human samples at 1:500 (fig 2). Exp Ther Med (2021) ncbi
BD Biosciences
mouse monoclonal (49/PRK1)
  • western blot knockout validation; mouse; loading ...; fig 2a
BD Biosciences Pkn1 antibody (BD Transduction, 610687) was used in western blot knockout validation on mouse samples (fig 2a). Front Synaptic Neurosci (2021) ncbi
mouse monoclonal (49/PRK1)
  • western blot; mouse; loading ...; fig 1f
BD Biosciences Pkn1 antibody (BD Transduction, 610687) was used in western blot on mouse samples (fig 1f). J Clin Invest (2018) ncbi
mouse monoclonal (49/PRK1)
  • chromatin immunoprecipitation; human; fig 4
BD Biosciences Pkn1 antibody (BD Transduction, 610687) was used in chromatin immunoprecipitation on human samples (fig 4). Mol Endocrinol (2016) ncbi
mouse monoclonal (49/PRK1)
  • western blot; mouse; fig s1
BD Biosciences Pkn1 antibody (BD biosciences, noca) was used in western blot on mouse samples (fig s1). Cell Rep (2016) ncbi
mouse monoclonal (49/PRK1)
  • western blot; human; 1:1000; fig 5
BD Biosciences Pkn1 antibody (BD Bioscience, 610687) was used in western blot on human samples at 1:1000 (fig 5). Nature (2015) ncbi
mouse monoclonal (49/PRK1)
  • western blot; rat
In order to investigate the role of NOS1AP in the nNOS-p38MAPK pathway, BD Biosciences Pkn1 antibody (BD Transduction, 49) was used in western blot on rat samples . J Neurosci (2013) ncbi
Articles Reviewed
  1. Wang X, Ge Y, Shi M, Dai H, Liu W, Wang P. Protein kinase N1 promotes proliferation and invasion of liver cancer. Exp Ther Med. 2021;21:651 pubmed publisher
  2. Safari M, Obexer D, Baier Bitterlich G, zur Nedden S. PKN1 Is a Novel Regulator of Hippocampal GluA1 Levels. Front Synaptic Neurosci. 2021;13:640495 pubmed publisher
  3. zur Nedden S, Eith R, Schwarzer C, Zanetti L, Seitter H, Fresser F, et al. Protein kinase N1 critically regulates cerebellar development and long-term function. J Clin Invest. 2018;128:2076-2088 pubmed publisher
  4. Ding Y, Lu L, Xuan C, Han J, Ye S, Cao T, et al. Di-n-butyl phthalate exposure negatively influences structural and functional neuroplasticity via Rho-GTPase signaling pathways. Food Chem Toxicol. 2017;105:34-43 pubmed publisher
  5. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  6. Park Y, Wood G, Kastner D, Chae J. Pyrin inflammasome activation and RhoA signaling in the autoinflammatory diseases FMF and HIDS. Nat Immunol. 2016;17:914-21 pubmed publisher
  7. Kim J, Yu J, Abdulkadir S, Chakravarti D. KAT8 Regulates Androgen Signaling in Prostate Cancer Cells. Mol Endocrinol. 2016;30:925-36 pubmed publisher
  8. Quétier I, Marshall J, Spencer Dene B, Lachmann S, Casamassima A, Franco C, et al. Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep. 2016;14:440-448 pubmed publisher
  9. Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  10. Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher