This is a Validated Antibody Database (VAD) review about mouse Pitx3, based on 5 published articles (read how Labome selects the articles), using Pitx3 antibody in all methods. It is aimed to help Labome visitors find the most suited Pitx3 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pitx3 synonym: Ptx3; pituitary homeobox 3; Pituitary homeobox 3 (Homeobox protein PITX3); aphakia; homeobox protein PITX3

Invitrogen
rabbit polyclonal
  • immunohistochemistry; mouse; 1:250; fig 5
In order to characterize sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain by primary cilia, Invitrogen Pitx3 antibody (Thermo Fischer Scientific, 38-2850) was used in immunohistochemistry on mouse samples at 1:250 (fig 5). Dev Biol (2016) ncbi
rabbit polyclonal
  • immunocytochemistry; mouse; 1:400; fig 6
In order to identify regulators of neurogenesis and neuronal survival, Invitrogen Pitx3 antibody (Invitrogen, 38-2850) was used in immunocytochemistry on mouse samples at 1:400 (fig 6). Nat Chem Biol (2013) ncbi
rabbit polyclonal
  • immunohistochemistry; human; 1:100; fig 3
  • immunohistochemistry; mouse; 1:100; fig 3
In order to determine the localization of Pitx3, Otx2, and DCC in the human brain, Invitrogen Pitx3 antibody (Zymed, 38-2850) was used in immunohistochemistry on human samples at 1:100 (fig 3) and in immunohistochemistry on mouse samples at 1:100 (fig 3). Neurobiol Aging (2013) ncbi
rabbit polyclonal
  • immunohistochemistry - frozen section; mouse; 1:200; fig 4
In order to investigate the role of Mecp2 in central dopaminergic neurons using a Rett syndrome mouse model, Invitrogen Pitx3 antibody (Zymed, 38-2850) was used in immunohistochemistry - frozen section on mouse samples at 1:200 (fig 4). Neurobiol Dis (2011) ncbi
rabbit polyclonal
  • immunocytochemistry; rat; 1:200; fig 1
In order to elucidate how to induce controlled differentiation of neural stem cells, Invitrogen Pitx3 antibody (Zymed, 38-2850) was used in immunocytochemistry on rat samples at 1:200 (fig 1). J Neurosci (2008) ncbi
Articles Reviewed
  1. Gazea M, Tasouri E, Tolve M, Bosch V, Kabanova A, Gojak C, et al. Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain. Dev Biol. 2016;409:55-71 pubmed publisher
  2. Theofilopoulos S, Wang Y, Kitambi S, Sacchetti P, Sousa K, Bodin K, et al. Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nat Chem Biol. 2013;9:126-33 pubmed publisher
  3. Reyes S, Fu Y, Double K, Cottam V, Thompson L, Kirik D, et al. Trophic factors differentiate dopamine neurons vulnerable to Parkinson's disease. Neurobiol Aging. 2013;34:873-86 pubmed publisher
  4. Panayotis N, Pratte M, Borges Correia A, Ghata A, Villard L, Roux J. Morphological and functional alterations in the substantia nigra pars compacta of the Mecp2-null mouse. Neurobiol Dis. 2011;41:385-97 pubmed publisher
  5. Roybon L, Hjalt T, Christophersen N, Li J, Brundin P. Effects on differentiation of embryonic ventral midbrain progenitors by Lmx1a, Msx1, Ngn2, and Pitx3. J Neurosci. 2008;28:3644-56 pubmed publisher