This is a Validated Antibody Database (VAD) review about mouse Pink1, based on 31 published articles (read how Labome selects the articles), using Pink1 antibody in all methods. It is aimed to help Labome visitors find the most suited Pink1 antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pink1 synonym: 1190006F07Rik; AU042772; AW557854; BRPK; mFLJ00387

Knockout validation
Novus Biologicals
domestic rabbit polyclonal (HH1/1784R)
  • western blot knockout validation; human; loading ...; fig s20c
Novus Biologicals Pink1 antibody (Novus, BC-100-494) was used in western blot knockout validation on human samples (fig s20c). Nucleic Acids Res (2017) ncbi
Novus Biologicals
domestic rabbit polyclonal (6C5cc)
  • western blot; mouse; 1:500-1:2000; loading ...; fig 5c
Novus Biologicals Pink1 antibody (Novus, NB100-493) was used in western blot on mouse samples at 1:500-1:2000 (fig 5c). Redox Biol (2021) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; mouse; 1:1000; loading ...; fig 5c
  • western blot; human; 1:1000; loading ...; fig 6f
Novus Biologicals Pink1 antibody (Novus, BC100-494) was used in western blot on mouse samples at 1:1000 (fig 5c) and in western blot on human samples at 1:1000 (fig 6f). JCI Insight (2021) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; rat; 1:50; loading ...; fig 3a
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494SS) was used in western blot on rat samples at 1:50 (fig 3a). Aging (Albany NY) (2020) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; mouse; loading ...; fig 4, 7
Novus Biologicals Pink1 antibody (Novus, CO,USA, BC100-494) was used in western blot on mouse samples (fig 4, 7). FASEB J (2020) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; mouse; 1:1000; loading ...; fig s2b
Novus Biologicals Pink1 antibody (NOVUS Biologicals, BC100-494) was used in western blot on mouse samples at 1:1000 (fig s2b). Sci Rep (2018) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; human; loading ...; fig 1a
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples (fig 1a). Cell Death Differ (2018) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; mouse; 1:1000; loading ...; fig 2a
Novus Biologicals Pink1 antibody (Novusbio, BC100-494) was used in western blot on mouse samples at 1:1000 (fig 2a). Endocrinology (2018) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; human; 1:1000; loading ...; fig 3e
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples at 1:1000 (fig 3e). J Biol Chem (2017) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; human; 1:1000; fig 4
Novus Biologicals Pink1 antibody (Novus, BC100-494) was used in western blot on human samples at 1:1000 (fig 4). Hum Mol Genet (2017) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • immunoprecipitation; human; loading ...; fig 3g
  • immunocytochemistry; human; loading ...; fig 3h
  • western blot; human; loading ...; fig 4a
Novus Biologicals Pink1 antibody (Novus, BC100-494) was used in immunoprecipitation on human samples (fig 3g), in immunocytochemistry on human samples (fig 3h) and in western blot on human samples (fig 4a). Oncotarget (2017) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot knockout validation; human; loading ...; fig s20c
Novus Biologicals Pink1 antibody (Novus, BC-100-494) was used in western blot knockout validation on human samples (fig s20c). Nucleic Acids Res (2017) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; human; loading ...; fig 4a
In order to investigate the contribution of PINK1 and PARKIN to cell death, Novus Biologicals Pink1 antibody (Novus, BC100-494) was used in western blot on human samples (fig 4a). J Biol Chem (2016) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • proximity ligation assay; human; fig 2
  • western blot; human; fig 1
In order to study how Parkin is responsible for polyubiquitination of apurinic/apyrimidinic endonuclease 1, Novus Biologicals Pink1 antibody (Novus, BC100-494) was used in proximity ligation assay on human samples (fig 2) and in western blot on human samples (fig 1). Mol Carcinog (2017) ncbi
domestic rabbit polyclonal (HH1/1784R)
  • western blot; human; loading ...; fig 3a
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used in western blot on human samples (fig 3a). J Neurochem (2016) ncbi
domestic rabbit polyclonal (HH1/1784R)
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used . Cell Signal (2015) ncbi
domestic rabbit polyclonal (HH1/1784R)
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used . J Biol Chem (2015) ncbi
domestic rabbit polyclonal (HH1/1784R)
In order to investigate how PINK1 recruits Parkin, Novus Biologicals Pink1 antibody (Santa Cruz Biotechnology, PN BC100-494) was used . J Cell Biol (2015) ncbi
domestic rabbit polyclonal (HH1/1784R)
Novus Biologicals Pink1 antibody (Novus, BC100-494) was used . EMBO Mol Med (2015) ncbi
domestic rabbit polyclonal (HH1/1784R)
Novus Biologicals Pink1 antibody (Novus Biological, BC100-494) was used . Autophagy (2015) ncbi
domestic rabbit polyclonal (HH1/1784R)
Novus Biologicals Pink1 antibody (Novus Biologicals, BC100-494) was used . Hum Mol Genet (2015) ncbi
Abcam
domestic rabbit polyclonal
  • western blot; human; 1:2500; loading ...; fig 1a
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on human samples at 1:2500 (fig 1a). Nat Commun (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 3h
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on mouse samples at 1:1000 (fig 3h). Front Cell Dev Biol (2021) ncbi
domestic rabbit polyclonal
  • western blot; rat; fig 7f
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on rat samples (fig 7f). Oxid Med Cell Longev (2021) ncbi
domestic rabbit polyclonal
  • western blot; mouse; loading ...; fig 6d
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on mouse samples (fig 6d). Oxid Med Cell Longev (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 6a
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on mouse samples at 1:1000 (fig 6a). Antioxidants (Basel) (2020) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:1000; loading ...; fig 5f
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on mouse samples at 1:1000 (fig 5f). J Neuroinflammation (2020) ncbi
domestic rabbit polyclonal
  • flow cytometry; mouse; 1:100-1:200; loading ...; fig s5e
  • flow cytometry; human; 1:100-1:200; loading ...; fig s5f
Abcam Pink1 antibody (Abcam, ab23707) was used in flow cytometry on mouse samples at 1:100-1:200 (fig s5e) and in flow cytometry on human samples at 1:100-1:200 (fig s5f). Cell Stem Cell (2018) ncbi
domestic rabbit polyclonal
  • western blot; human; loading ...; fig 1e
Abcam Pink1 antibody (Abcam, ab23707) was used in western blot on human samples (fig 1e). Cell Syst (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry; human; fig 2
  • western blot; human; fig 2
Abcam Pink1 antibody (Abcam, 23707) was used in immunohistochemistry on human samples (fig 2) and in western blot on human samples (fig 2). J Immunol (2016) ncbi
domestic rabbit polyclonal
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; 1:1000; fig 5
Abcam Pink1 antibody (Abcam, ab23707) was used in immunocytochemistry on human samples at 1:500 (fig 5) and in western blot on human samples at 1:1000 (fig 5). Sci Rep (2016) ncbi
Cayman Chemical
polyclonal
  • western blot; mouse; 1:500; loading ...; fig 3a
Cayman Chemical Pink1 antibody (Caymanchem, 10006283) was used in western blot on mouse samples at 1:500 (fig 3a). Nature (2019) ncbi
Articles Reviewed
  1. Chiang S, Braidy N, Maleki S, Lal S, Richardson D, Huang M. Mechanisms of impaired mitochondrial homeostasis and NAD+ metabolism in a model of mitochondrial heart disease exhibiting redox active iron accumulation. Redox Biol. 2021;46:102038 pubmed publisher
  2. Matsui H, Ito J, Matsui N, Uechi T, Onodera O, Kakita A. Cytosolic dsDNA of mitochondrial origin induces cytotoxicity and neurodegeneration in cellular and zebrafish models of Parkinson's disease. Nat Commun. 2021;12:3101 pubmed publisher
  3. Xu L, Humphries F, Delagic N, Wang B, Holland A, Edgar K, et al. ECSIT is a critical limiting factor for cardiac function. JCI Insight. 2021;6: pubmed publisher
  4. Tian F, Zhang Y. Overexpression of SERCA2a Alleviates Cardiac Microvascular Ischemic Injury by Suppressing Mfn2-Mediated ER/Mitochondrial Calcium Tethering. Front Cell Dev Biol. 2021;9:636553 pubmed publisher
  5. Huo S, Shi W, Ma H, Yan D, Luo P, Guo J, et al. Alleviation of Inflammation and Oxidative Stress in Pressure Overload-Induced Cardiac Remodeling and Heart Failure via IL-6/STAT3 Inhibition by Raloxifene. Oxid Med Cell Longev. 2021;2021:6699054 pubmed publisher
  6. Xu Y, Zhi F, Mao J, Peng Y, Shao N, Balboni G, et al. δ-opioid receptor activation protects against Parkinson's disease-related mitochondrial dysfunction by enhancing PINK1/Parkin-dependent mitophagy. Aging (Albany NY). 2020;12:25035-25059 pubmed publisher
  7. Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher
  8. Meza Torres C, Hernández Camacho J, Cortés Rodríguez A, Fang L, Bui Thanh T, Rodríguez Bies E, et al. Resveratrol Regulates the Expression of Genes Involved in CoQ Synthesis in Liver in Mice Fed with High Fat Diet. Antioxidants (Basel). 2020;9: pubmed publisher
  9. Zhang S, Hu L, Jiang J, Li H, Wu Q, Ooi K, et al. HMGB1/RAGE axis mediates stress-induced RVLM neuroinflammation in mice via impairing mitophagy flux in microglia. J Neuroinflammation. 2020;17:15 pubmed publisher
  10. Huang Y, Gu C, Wang Q, Xu L, Chen J, Zhou W, et al. The protective effort of GPCR kinase 2-interacting protein-1 in neurons via promoting Beclin1-Parkin induced mitophagy at the early stage of spinal cord ischemia-reperfusion injury. FASEB J. 2020;34:2055-2074 pubmed publisher
  11. Hoshino A, Wang W, Wada S, McDermott Roe C, Evans C, Gosis B, et al. The ADP/ATP translocase drives mitophagy independent of nucleotide exchange. Nature. 2019;575:375-379 pubmed publisher
  12. Walsh T, van den Bosch M, Lewis K, Williams C, Poole A. Loss of the mitochondrial kinase PINK1 does not alter platelet function. Sci Rep. 2018;8:14377 pubmed publisher
  13. Baumgartner C, Toifl S, Farlik M, Halbritter F, Scheicher R, Fischer I, et al. An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion. Cell Stem Cell. 2018;22:879-892.e6 pubmed publisher
  14. Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed publisher
  15. Malty R, Aoki H, Kumar A, Phanse S, Amin S, Zhang Q, et al. A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling. Cell Syst. 2017;5:564-577.e12 pubmed publisher
  16. Viana Huete V, Guillen C, García G, Fernandez S, García Aguilar A, Kahn C, et al. Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity. Endocrinology. 2018;159:323-340 pubmed publisher
  17. Xiao B, Goh J, Xiao L, Xian H, Lim K, Liou Y. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J Biol Chem. 2017;292:16697-16708 pubmed publisher
  18. Shiba Fukushima K, Ishikawa K, Inoshita T, Izawa N, Takanashi M, Sato S, et al. Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease. Hum Mol Genet. 2017;26:3172-3185 pubmed publisher
  19. Li G, Fu R, Shen H, Zhou J, Hu X, Liu Y, et al. Polyphyllin I induces mitophagic and apoptotic cell death in human breast cancer cells by increasing mitochondrial PINK1 levels. Oncotarget. 2017;8:10359-10374 pubmed publisher
  20. Wettengel J, Reautschnig P, Geisler S, Kahle P, Stafforst T. Harnessing human ADAR2 for RNA repair - Recoding a PINK1 mutation rescues mitophagy. Nucleic Acids Res. 2017;45:2797-2808 pubmed publisher
  21. Akabane S, Matsuzaki K, Yamashita S, Arai K, Okatsu K, Kanki T, et al. Constitutive Activation of PINK1 Protein Leads to Proteasome-mediated and Non-apoptotic Cell Death Independently of Mitochondrial Autophagy. J Biol Chem. 2016;291:16162-74 pubmed publisher
  22. Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher
  23. Scott T, Wicker C, Suganya R, Dhar B, Pittman T, Horbinski C, et al. Polyubiquitination of apurinic/apyrimidinic endonuclease 1 by Parkin. Mol Carcinog. 2017;56:325-336 pubmed publisher
  24. Qi Y, Qiu Q, Gu X, Tian Y, Zhang Y. ATM mediates spermidine-induced mitophagy via PINK1 and Parkin regulation in human fibroblasts. Sci Rep. 2016;6:24700 pubmed publisher
  25. Ivankovic D, Chau K, Schapira A, Gegg M. Mitochondrial and lysosomal biogenesis are activated following PINK1/parkin-mediated mitophagy. J Neurochem. 2016;136:388-402 pubmed publisher
  26. Park S, Choi S, Yoo S, Nah J, Jeong E, Kim H, et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell Signal. 2015;27:1824-30 pubmed publisher
  27. Lim G, Chua D, Basil A, Chan H, Chai C, Arumugam T, et al. Cytosolic PTEN-induced Putative Kinase 1 Is Stabilized by the NF-κB Pathway and Promotes Non-selective Mitophagy. J Biol Chem. 2015;290:16882-93 pubmed publisher
  28. Okatsu K, Koyano F, Kimura M, Kosako H, Saeki Y, Tanaka K, et al. Phosphorylated ubiquitin chain is the genuine Parkin receptor. J Cell Biol. 2015;209:111-28 pubmed publisher
  29. Seillier M, Pouyet L, N Guessan P, Nollet M, Capo F, Guillaumond F, et al. Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1. EMBO Mol Med. 2015;7:802-18 pubmed publisher
  30. Jabir M, Hopkins L, Ritchie N, Ullah I, Bayes H, Li D, et al. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy. 2015;11:166-82 pubmed publisher
  31. Choi H, Choi Y, Kang H, Lim E, Park S, Lee H, et al. PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death. Hum Mol Genet. 2015;24:1127-41 pubmed publisher