This is a Validated Antibody Database (VAD) review about mouse Pik3cg, based on 27 published articles (read how Labome selects the articles), using Pik3cg antibody in all methods. It is aimed to help Labome visitors find the most suited Pik3cg antibody. Please note the number of articles fluctuates since newly identified citations are added and citations for discontinued catalog numbers are removed regularly.
Pik3cg synonym: 5830428L06Rik; PI3Kgamma; p110gamma; p120-PI3K

Knockout validation
BD Biosciences
mouse monoclonal (17/PI3-Kinase p170)
  • western blot knockout validation; mouse; fig 1d
  • western blot; rat; fig 1d
BD Biosciences Pik3cg antibody (BD, 611046) was used in western blot knockout validation on mouse samples (fig 1d) and in western blot on rat samples (fig 1d). Mol Cell Biol (2011) ncbi
Santa Cruz Biotechnology
mouse monoclonal (D-12)
  • immunohistochemistry; human; loading ...; fig 2a
  • western blot; human; loading ...; fig 3b
Santa Cruz Biotechnology Pik3cg antibody (santa cruz, sc-166365) was used in immunohistochemistry on human samples (fig 2a) and in western blot on human samples (fig 3b). Oncotarget (2016) ncbi
Abcam
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 9c
  • western blot; mouse; 1:1000; loading ...; fig 9a
Abcam Pik3cg antibody (Abcam, ab154598) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 9c) and in western blot on mouse samples at 1:1000 (fig 9a). Front Pharmacol (2021) ncbi
Invitrogen
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 8a
Invitrogen Pik3cg antibody (Thermo-Fisher, PA5-28070) was used in immunohistochemistry - paraffin section on mouse samples at 1:100 (fig 8a). Int J Mol Sci (2021) ncbi
Cell Signaling Technology
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 7a
Cell Signaling Technology Pik3cg antibody (Cell Signaling, 3358) was used in western blot on human samples (fig 7a). Autophagy (2019) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; loading ...; fig s4b
Cell Signaling Technology Pik3cg antibody (Cell Signaling Technology, D55D5) was used in western blot on human samples (fig s4b). Mol Biol Cell (2018) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; fig 5a
Cell Signaling Technology Pik3cg antibody (Cell Signaling, 5405) was used in western blot on human samples (fig 5a). Inflammation (2018) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; mouse; 1:1000; loading ...; fig 3c
Cell Signaling Technology Pik3cg antibody (cell signaling, 5405) was used in western blot on mouse samples at 1:1000 (fig 3c). Oncogene (2017) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; rat; 1:1000; loading ...; fig 5f
Cell Signaling Technology Pik3cg antibody (Cell Signaling, 3358S) was used in western blot on rat samples at 1:1000 (fig 5f). Brain Behav Immun (2017) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 1s1f
Cell Signaling Technology Pik3cg antibody (CST, 3358) was used in western blot on human samples (fig 1s1f). elife (2017) ncbi
domestic rabbit polyclonal
  • immunohistochemistry - paraffin section; human
Cell Signaling Technology Pik3cg antibody (Cell Signalling, 4252) was used in immunohistochemistry - paraffin section on human samples . Respir Res (2016) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; loading ...; fig 6a
Cell Signaling Technology Pik3cg antibody (Cell Signaling, 3358) was used in western blot on human samples (fig 6a). Autophagy (2016) ncbi
domestic rabbit monoclonal (D55D5)
  • western blot; human; loading ...; fig 4
In order to find tumor types sensitive to phosphoinositide 3-kinase pathway inhibitors, Cell Signaling Technology Pik3cg antibody (Cell Signaling, 5405) was used in western blot on human samples (fig 4). Oncotarget (2016) ncbi
domestic rabbit monoclonal (D4E2)
  • immunocytochemistry; human; 1:500; fig 5
  • western blot; human; 1:500; fig 5
In order to investigate impairment of autophagy flux and induction of cell death independent of necroptosis and apoptosis by dual PI-3 kinase/mTOR inhibition, Cell Signaling Technology Pik3cg antibody (Cell Signaling, 3358) was used in immunocytochemistry on human samples at 1:500 (fig 5) and in western blot on human samples at 1:500 (fig 5). Oncotarget (2016) ncbi
domestic rabbit polyclonal
  • western blot; mouse; 1:200
In order to elucidate the role of IL-33/IL-33 receptor signaling in mouse models of neuropathic pain, Cell Signaling Technology Pik3cg antibody (Cell Signaling Technology, 4252) was used in western blot on mouse samples at 1:200. FASEB J (2016) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; rat; 1:1000
Cell Signaling Technology Pik3cg antibody (Cell Signaling, D4E2) was used in western blot on rat samples at 1:1000. PLoS ONE (2014) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; mouse; 1:500
Cell Signaling Technology Pik3cg antibody (Cell Signaling Technologies, 3358) was used in western blot on mouse samples at 1:500. Neurobiol Dis (2014) ncbi
domestic rabbit monoclonal (D4E2)
  • western blot; human; 1:1000
Cell Signaling Technology Pik3cg antibody (Cell Signaling, 3358) was used in western blot on human samples at 1:1000. Cell Death Dis (2013) ncbi
BD Biosciences
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; human; loading ...; fig s3a
BD Biosciences Pik3cg antibody (BD Bioscience, 611046) was used in western blot on human samples (fig s3a). Cell (2018) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; fig s10
BD Biosciences Pik3cg antibody (BD Biosciences, 610045) was used in western blot on human samples (fig s10). Nat Commun (2016) ncbi
mouse monoclonal (4/PI3-Kinase)
  • immunohistochemistry; human; 1:50; tbl 2
In order to evaluate the reliance on EBV or NF-kappaB signaling instead of B-cell receptor signaling in regards to complete phenotypic characterization of PTLD, BD Biosciences Pik3cg antibody (BD Laboratories, 610046) was used in immunohistochemistry on human samples at 1:50 (tbl 2). Hematol Oncol (2017) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; loading ...; fig 1c
BD Biosciences Pik3cg antibody (BD Biosciences, 610045) was used in western blot on human samples (fig 1c). Mar Drugs (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; 1:2500; loading ...; fig 5f
BD Biosciences Pik3cg antibody (BD Biosciences, 4/PI3-Kinase) was used in western blot on human samples at 1:2500 (fig 5f). Oncotarget (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • other; mouse; 1:2500; fig s1
In order to identify host signaling dynamics upon Burkholderia spp. infection by a reverse-phase protein microarray-based screen, BD Biosciences Pik3cg antibody (BD, 610045) was used in other on mouse samples at 1:2500 (fig s1). Front Microbiol (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; rat; fig 10
BD Biosciences Pik3cg antibody (BD Biosciences, 610045) was used in western blot on rat samples (fig 10). PLoS ONE (2015) ncbi
mouse monoclonal (17/PI3-Kinase p170)
  • western blot; human; fig 1
BD Biosciences Pik3cg antibody (BD Biosciences, 611046) was used in western blot on human samples (fig 1). J Biol Chem (2015) ncbi
mouse monoclonal (4/PI3-Kinase)
  • western blot; human; 1:5000
BD Biosciences Pik3cg antibody (BD Bioscience, 610045) was used in western blot on human samples at 1:5000. FASEB J (2013) ncbi
mouse monoclonal (17/PI3-Kinase p170)
  • western blot knockout validation; mouse; fig 1d
  • western blot; rat; fig 1d
BD Biosciences Pik3cg antibody (BD, 611046) was used in western blot knockout validation on mouse samples (fig 1d) and in western blot on rat samples (fig 1d). Mol Cell Biol (2011) ncbi
Articles Reviewed
  1. Sferra R, Pompili S, Cappariello A, Gaudio E, Latella G, Vetuschi A. Prolonged Chronic Consumption of a High Fat with Sucrose Diet Alters the Morphology of the Small Intestine. Int J Mol Sci. 2021;22: pubmed publisher
  2. Zhou H, Li G, Wang Y, Jiang R, Li Y, Wang H, et al. Microbial Metabolite Sodium Butyrate Attenuates Cartilage Degradation by Restoring Impaired Autophagy and Autophagic Flux in Osteoarthritis Development. Front Pharmacol. 2021;12:659597 pubmed publisher
  3. Birgisdottir A, Mouilleron S, Bhujabal Z, Wirth M, Sjøttem E, Evjen G, et al. Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs. Autophagy. 2019;15:1333-1355 pubmed publisher
  4. Almeida Souza L, Frank R, García Nafría J, Colussi A, Gunawardana N, Johnson C, et al. A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018;174:325-337.e14 pubmed publisher
  5. Redka D, Gutschow M, Grinstein S, Canton J. Differential ability of proinflammatory and anti-inflammatory macrophages to perform macropinocytosis. Mol Biol Cell. 2018;29:53-65 pubmed publisher
  6. Wang N, Li J, Zhao T, Li S, Shen C, Li D, et al. FGF-21 Plays a Crucial Role in the Glucose Uptake of Activated Monocytes. Inflammation. 2018;41:73-80 pubmed publisher
  7. Simond A, Rao T, Zuo D, Zhao J, Muller W. ErbB2-positive mammary tumors can escape PI3K-p110α loss through downregulation of the Pten tumor suppressor. Oncogene. 2017;36:6059-6066 pubmed publisher
  8. Rong H, Zhao Z, Feng J, Lei Y, Wu H, Sun R, et al. The effects of dexmedetomidine pretreatment on the pro- and anti-inflammation systems after spinal cord injury in rats. Brain Behav Immun. 2017;64:195-207 pubmed publisher
  9. Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
  10. Southworth T, Plumb J, Gupta V, Pearson J, Ramis I, Lehner M, et al. Anti-inflammatory potential of PI3K? and JAK inhibitors in asthma patients. Respir Res. 2016;17:124 pubmed
  11. Yuan W, Guo Y, Li X, Deng M, Shen Z, Bo C, et al. MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. Oncotarget. 2016;7:60230-60244 pubmed publisher
  12. Kaushik A, Shojaie A, Panzitt K, Sonavane R, Venghatakrishnan H, Manikkam M, et al. Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer. Nat Commun. 2016;7:11612 pubmed publisher
  13. Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher
  14. Lynch J, McEwen R, Crafter C, McDermott U, Garnett M, Barry S, et al. Identification of differential PI3K pathway target dependencies in T-cell acute lymphoblastic leukemia through a large cancer cell panel screen. Oncotarget. 2016;7:22128-39 pubmed publisher
  15. Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  16. Menter T, Dickenmann M, Juskevicius D, Steiger J, Dirnhofer S, Tzankov A. Comprehensive phenotypic characterization of PTLD reveals potential reliance on EBV or NF-κB signalling instead of B-cell receptor signalling. Hematol Oncol. 2017;35:187-197 pubmed publisher
  17. Ampofo E, Später T, Müller I, Eichler H, Menger M, Laschke M. The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity. Mar Drugs. 2015;13:6774-91 pubmed publisher
  18. Pavon M, Arroyo Solera I, Tellez Gabriel M, Leon X, Virós D, Lopez M, et al. Enhanced cell migration and apoptosis resistance may underlie the association between high SERPINE1 expression and poor outcome in head and neck carcinoma patients. Oncotarget. 2015;6:29016-33 pubmed publisher
  19. Zarpelon A, Rodrigues F, Lopes A, Souza G, Carvalho T, Pinto L, et al. Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain. FASEB J. 2016;30:54-65 pubmed publisher
  20. Chiang C, Uzoma I, Lane D, Memišević V, Alem F, Yao K, et al. A reverse-phase protein microarray-based screen identifies host signaling dynamics upon Burkholderia spp. infection. Front Microbiol. 2015;6:683 pubmed publisher
  21. Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed publisher
  22. Aki S, Yoshioka K, Okamoto Y, Takuwa N, Takuwa Y. Phosphatidylinositol 3-kinase class II α-isoform PI3K-C2α is required for transforming growth factor β-induced Smad signaling in endothelial cells. J Biol Chem. 2015;290:6086-105 pubmed publisher
  23. Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed publisher
  24. Morabito M, Berman D, Schneider R, Zhang Y, Leibel R, Small S. Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease. Neurobiol Dis. 2014;65:188-92 pubmed publisher
  25. Bauckman K, Haller E, Flores I, Nanjundan M. Iron modulates cell survival in a Ras- and MAPK-dependent manner in ovarian cells. Cell Death Dis. 2013;4:e592 pubmed publisher
  26. van der Vorst E, Vanags L, Dunn L, Prosser H, Rye K, Bursill C. High-density lipoproteins suppress chemokine expression and proliferation in human vascular smooth muscle cells. FASEB J. 2013;27:1413-25 pubmed publisher
  27. Harris D, Vogel P, Wims M, Moberg K, Humphries J, Jhaver K, et al. Requirement for class II phosphoinositide 3-kinase C2alpha in maintenance of glomerular structure and function. Mol Cell Biol. 2011;31:63-80 pubmed publisher